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Gill tissues of the mussel Mytilus edulis chilensis   : A new source for antimicrobial peptides, 12/2005
Antimicrobial peptides are small-sized, cationic and amphipathic molecules able to neutralize pathogenic microorganisms. Their antimicrobial effects tie them... 
antimicrobial peptides, biochemical characterization, gill tissues, in vitro activity, mussels
Journal
Protein Expression and Purification, ISSN 1046-5928, 09/2019, Volume 161, pp. 17 - 27
A new alginate lyase gene of was cloned from an alginate-degrading marine bacterium sp. ALW1. The gene contained 2220 bp and encoded a 739-amino acid protein... 
Biochemical characterization | Microbulbifer | Cloning | Exo-oligoalginate lyase
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 03/2016, Volume 57, Issue 3, pp. 367 - 371
In prostate cancer (PC) patients, the differentiation between lung metastases and lesions of different origin, for example, primary lung cancer, is a common... 
lung cancer | prostate cancer | DESIGN | MEMBRANE ANTIGEN-EXPRESSION | pulmonary metastasis | BIOCHEMICAL-CHARACTERIZATION | PATTERNS | RECURRENCE | INHIBITOR | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Ga-68-PSMA
Journal Article
Journal of Pure and Applied Microbiology, ISSN 0973-7510, 03/2017, Volume 11, Issue 1, pp. 379 - 385
Journal Article
DRUG DISCOVERY TODAY, ISSN 1359-6446, 04/2012, Volume 17, Issue 7-8, pp. 359 - 366
The A(3) adenosine receptor (A(3)AR) coupled to G(i) (inhibitory regulative guanine nucleotide-binding protein) mediates anti-inflammatory, anticancer and... 
RHEUMATOID-ARTHRITIS | CELLS | ACTIVATION | COLON-CARCINOMA GROWTH | MYOCARDIAL-ISCHEMIA | BIOCHEMICAL-CHARACTERIZATION | PHARMACOLOGY & PHARMACY | FACTOR-KAPPA-B | UP-REGULATION | IB-MECA | CANCER-THERAPY
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 08/2017, Volume 13, Issue 8, pp. 867 - 867
Humans express at least two distinct beta-glucuronidase enzymes that are involved in disease: exo-acting beta-glucuronidase (GUSB), whose deficiency gives rise... 
SYSTEM | ACTIVATION | ENZYME | CATHEPSIN-L | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL-CHARACTERIZATION | STRUCTURAL-CHARACTERIZATION | HEPARAN-SULFATE | INHIBITORS | EXPRESSION | IN-SITU
Journal Article
NATURE STRUCTURAL & MOLECULAR BIOLOGY, ISSN 1545-9993, 12/2015, Volume 22, Issue 12, pp. 1016 - 1022
Heparan sulfate (HS) is a glycosaminoglycan that forms a key component of the extracellular matrix (ECM). Breakdown of HS is carried out by heparanase (HPSE),... 
ANGIOGENESIS | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SOLUTION CONFORMATION | BIOCHEMICAL-CHARACTERIZATION | FIBROBLAST-GROWTH-FACTOR | HEPARIN | CELL BIOLOGY | BIOPHYSICS | CANCER METASTASIS | SULFATE | EXTRACELLULAR-MATRIX | GLYCOSYL HYDROLASES
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 12/2016, Volume 59, Issue 23, pp. 10564 - 10576
In this study, we describe the design and synthesis of new N-5-substituted-2-(2-furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamines (2-18) and their pharmacological... 
NEUROPATHIC PAIN | CHEMISTRY, MEDICINAL | BIOCHEMICAL-CHARACTERIZATION | SIMPLIFIED ANALOGS | HYPERALGESIA | STRUCTURE-AFFINITY RELATIONSHIPS | BLOCKADE | BINDING | ANTAGONISTS. SYNTHESIS | DELETION | SKELETON
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 09/2018, Volume 46, Issue 16, pp. 8347 - 8356
Replication of damaged DNA is challenging because lesions in the replication template frequently interfere with an orderly progression of the replisome. In... 
RRM3 | COMPLEX | REPAIR | GENOME INSTABILITY | SGS1 | TOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPLICATION FORK | CHECKPOINT CLAMP | BIOCHEMICAL-CHARACTERIZATION | SACCHAROMYCES-CEREVISIAE
Journal Article
Biocatalysis and Agricultural Biotechnology, ISSN 1878-8181, 07/2014, Volume 3, Issue 3, pp. 20 - 25
This study reports the production optimization and the biochemical characterization of a partially purified protease obtained from LBA 01 under solid state... 
Biochemical characterization | Wastes | Protease | Solid state fermentation
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2019, Volume 512, Issue 1, pp. 7 - 13
Fibrosis is a serious health problem often leading to accompanying organ failure. During the manifestation of the disease, an accumulation of different... 
Extracellular matrix | Proteoglycans | Uridine-diphosphate | Xylosyltransferase | Fibrosis | BIOPHYSICS | MARKER | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL-CHARACTERIZATION | ANIMAL-MODEL | URIDINE
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 04/2019, Volume 476, Issue 7, pp. 1109 - 1119
The biologically important carnitine biosynthesis pathway in humans proceeds via four enzymatic steps. The first step in carnitine biosynthesis is catalyzed by... 
CARNITINE BIOSYNTHESIS | ENZYME | VARIANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | N6-TRIMETHYL-LYSINE | GAMMA-BUTYROBETAINE | BIOCHEMICAL-CHARACTERIZATION | BINDING | DEFICIENCY
Journal Article
JOURNAL OF BIOCHEMISTRY, ISSN 0021-924X, 02/2015, Volume 157, Issue 2, pp. 81 - 89
Lysophosphatidic acid (LPA) is one of the simplest glycerophospholipids with one fatty acid chain and a phosphate group as a polar head. Although LPA had been... 
G protein-coupled receptor | PA-PLA | autotaxin | LYSOPHOSPHOLIPASE-D ACTIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipid mediator | BIOCHEMICAL-CHARACTERIZATION | LUNG INJURY | LPA-PRODUCING ENZYME | NEUROPATHIC PAIN | IN-VITRO | lysophosphatidic acid | PROTEIN-COUPLED RECEPTOR | HUMAN HAIR-GROWTH | EDG-FAMILY | MOUSE UTERUS
Journal Article
Journal of Pure and Applied Microbiology, ISSN 0973-7510, 12/2017, Volume 11, Issue 4, pp. 1973 - 1982
Journal Article
PLOS ONE, ISSN 1932-6203, 06/2015, Volume 10, Issue 6
Background Autotaxin (ATX) is a secreted enzyme that converts lysophosphatidylcholine to lysophosphatidic acid, a potent bioactive lipid mediator, through its... 
LYSOPHOSPHOLIPASE-D | ACTIVATION | PROTEIN | LYSOPHOSPHATIDIC ACID | MULTIDISCIPLINARY SCIENCES | BIOCHEMICAL-CHARACTERIZATION | DIFFERENTIATION | IDENTIFICATION | EXPRESSION | CANCER | MOTILITY
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 02/2019, Volume 662, pp. 169 - 176
A new mucin-binding lectin (AFL) was isolated from the marine sponge . AFL was purified by affinity chromatography on Sepharose™ matrix. Its hemagglutinating... 
Lectin | Marine sponge | Antibiofilm | BIOPHYSICS | PROTEIN SECONDARY STRUCTURE | ACL-I | BIOCHEMISTRY & MOLECULAR BIOLOGY | PURIFICATION | BIOCHEMICAL-CHARACTERIZATION | GALACTOSE-SPECIFIC LECTIN
Journal Article
International Dairy Journal, ISSN 0958-6946, 10/2019, Volume 97, pp. 201 - 208
Antioxidant and angiotensin-I converting enzyme inhibitory (ACE-I) activities of bioactive peptide fractions from camel milk fermented by PTCC 1899 were... 
BIOACTIVE PEPTIDES | PROTEIN | ASSAY | BOVINE-MILK | FOOD SCIENCE & TECHNOLOGY | PURIFICATION | BIOCHEMICAL-CHARACTERIZATION | ANGIOTENSIN-CONVERTING ENZYME | WHEY | HYDROLYSATE | LACTOBACILLUS-RHAMNOSUS
Journal Article
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