X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (282252) 282252
Publication (31128) 31128
Book Chapter (1922) 1922
Book Review (1746) 1746
Newspaper Article (1516) 1516
Newsletter (1009) 1009
Book / eBook (384) 384
Conference Proceeding (348) 348
Dissertation (155) 155
Magazine Article (59) 59
Government Document (35) 35
Data Set (29) 29
Reference (21) 21
Web Resource (9) 9
Paper (7) 7
Trade Publication Article (6) 6
Transcript (6) 6
Presentation (2) 2
Streaming Video (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (147061) 147061
humans (122678) 122678
index medicus (98874) 98874
mice (61209) 61209
male (59783) 59783
biochemistry & molecular biology (51319) 51319
female (48982) 48982
rats (48507) 48507
biosynthesis (37721) 37721
cells, cultured (35759) 35759
expression (35098) 35098
cell biology (31805) 31805
proteins (28248) 28248
gene expression (26629) 26629
cell line (24338) 24338
oncology (22095) 22095
immunology (21821) 21821
protein biosynthesis (21381) 21381
analysis (21288) 21288
physiological aspects (21166) 21166
pharmacology & pharmacy (20311) 20311
research (20221) 20221
apoptosis (19304) 19304
molecular sequence data (19269) 19269
cell line, tumor (18409) 18409
activation (17412) 17412
kinetics (17160) 17160
cells (17130) 17130
research article (16908) 16908
gene-expression (16746) 16746
signal transduction (16615) 16615
rna, messenger - biosynthesis (16291) 16291
enzymes (16265) 16265
neurosciences (15943) 15943
phosphorylation (15901) 15901
article (15246) 15246
cancer (15106) 15106
adult (14882) 14882
middle aged (14415) 14415
amino acid sequence (14186) 14186
enzyme inhibitors - pharmacology (14045) 14045
dose-response relationship, drug (13945) 13945
microbiology (13808) 13808
time factors (13519) 13519
immunohistochemistry (13149) 13149
multidisciplinary sciences (13048) 13048
genes (12991) 12991
inhibition (12881) 12881
rna, messenger - genetics (12755) 12755
blotting, western (12640) 12640
metabolism (12600) 12600
rats, sprague-dawley (12519) 12519
mice, inbred c57bl (12374) 12374
rna, messenger - metabolism (12371) 12371
base sequence (12356) 12356
biotechnology & applied microbiology (12101) 12101
protein (12036) 12036
genetic aspects (11671) 11671
mutation (11421) 11421
gene (11285) 11285
plant sciences (11258) 11258
reverse transcriptase polymerase chain reaction (10897) 10897
in-vitro (10783) 10783
transfection (10754) 10754
in vitro techniques (10725) 10725
life sciences (10701) 10701
inflammation (10678) 10678
growth (10359) 10359
endocrinology & metabolism (10354) 10354
tumor cells, cultured (10339) 10339
medicine (10328) 10328
aged (10190) 10190
identification (9889) 9889
rna (9825) 9825
physiology (9649) 9649
biophysics (9602) 9602
gene expression regulation (9401) 9401
biology (9306) 9306
oxidative stress (9266) 9266
health aspects (9158) 9158
messenger-rna (9106) 9106
biochemistry (8807) 8807
in-vivo (8676) 8676
apoptosis - drug effects (8494) 8494
rats, wistar (8396) 8396
protein binding (8194) 8194
nitric oxide - biosynthesis (8113) 8113
science (8103) 8103
medicine, research & experimental (8084) 8084
up-regulation (8078) 8078
dna - biosynthesis (8048) 8048
escherichia-coli (7890) 7890
nitric oxide (7788) 7788
transcription, genetic (7717) 7717
mice, inbred balb c (7715) 7715
kinases (7694) 7694
signal transduction - drug effects (7650) 7650
hematology (7646) 7646
rodents (7577) 7577
cytokines (7563) 7563
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (248) 248
UofT at Mississauga - Stacks (52) 52
UTL at Downsview - May be requested (24) 24
Earth Sciences (Noranda) - Stacks (16) 16
Chemistry (A D Allen) - Stacks (15) 15
Collection Dvlpm't (Acquisitions) - Closed Orders (14) 14
UofT at Scarborough - Stacks (13) 13
Collection Dvlpm't (Acquisitions) - Vendor file (11) 11
Engineering & Comp. Sci. - Stacks (11) 11
Online Resources - Online (10) 10
UofT at Scarborough - Withdrawn (4) 4
Chemistry (A D Allen) - May be requested in 6-10 wks (2) 2
Collection Dvlpm't (Acquisitions) - Cancelled Order (2) 2
Physics - Stacks (2) 2
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
Trinity College (John W Graham) - Stacks (2) 2
UofT at Scarborough - May be requested in 6-10 wks (2) 2
Earth Sciences (Noranda) - Circulation Desk (1) 1
Earth Sciences (Noranda) - Oversize (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reserve desk (1) 1
Gerstein Science - Theses (1) 1
Holland Bloorview Kids Rehabilitation - Stacks (1) 1
Robarts - Stacks (1) 1
St. Michael's College (John M. Kelly) - Circulation Desk (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
Trinity College (John W Graham) - Oversize (1) 1
University Archives - Archives (1) 1
UofT at Mississauga - Circulation Desk (1) 1
UofT at Mississauga - Missing (1) 1
UofT at Mississauga - Periodical Stacks (1) 1
UofT at Mississauga - Reference (1) 1
Victoria University E.J. Pratt - Circulation Desk (1) 1
Victoria University E.J. Pratt - Oversize (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (282875) 282875
Japanese (3009) 3009
Russian (1187) 1187
Chinese (1083) 1083
French (415) 415
German (266) 266
Spanish (121) 121
Polish (83) 83
Ukrainian (63) 63
Italian (47) 47
Portuguese (38) 38
Dutch (31) 31
Czech (21) 21
Hungarian (20) 20
Korean (20) 20
Danish (9) 9
Slovak (9) 9
Bulgarian (7) 7
Swedish (7) 7
Turkish (7) 7
Finnish (6) 6
Norwegian (6) 6
Hebrew (5) 5
Croatian (4) 4
Serbian (4) 4
Romanian (3) 3
Slovenian (3) 3
Lithuanian (2) 2
Persian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Clinical Oncology, ISSN 0732-183X, 07/2017, Volume 35, Issue 19, pp. 2193 - 2202
Purpose Data suggest that DNA damage by poly (ADP-ribose) polymerase inhibition and/or reduced vascular endothelial growth factor signaling by vascular... 
SENSITIVE OVARIAN-CANCER | MULTICENTER | ANTI-PD-1 | ONCOLOGY | ANTITUMOR-ACTIVITY | NIVOLUMAB | Piperazines - administration & dosage | Vascular Endothelial Growth Factor Receptor-1 - antagonists & inhibitors | Phthalazines - pharmacokinetics | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Quinazolines - pharmacokinetics | Protein Kinase Inhibitors - adverse effects | Dose-Response Relationship, Drug | Genital Neoplasms, Female - drug therapy | Adult | Female | Quinazolines - administration & dosage | Piperazines - pharmacokinetics | Phthalazines - administration & dosage | Antibodies, Monoclonal - pharmacokinetics | Genital Neoplasms, Female - immunology | B7-H1 Antigen - immunology | Piperazines - adverse effects | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Genital Neoplasms, Female - metabolism | Protein Kinase Inhibitors - administration & dosage | B7-H1 Antigen - antagonists & inhibitors | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | B7-H1 Antigen - biosynthesis | Quinazolines - adverse effects | Aged | Genital Neoplasms, Female - pathology | Phthalazines - adverse effects | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus | Phase I and Clinical Pharmacology | Combined Modality | Breast Cancer | ORIGINAL REPORTS
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 09/2011, Volume 118, Issue 6, pp. 1032 - 1042
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2004, Volume 172, Issue 1, pp. 567 - 576
The signaling mechanism by which the anti-inflammatory cytokine IL-10 mediates suppression of proinflammatory cytokine synthesis remains largely unknown.... 
RHEUMATOID-ARTHRITIS | TUMOR-NECROSIS-FACTOR | DNA-BINDING | HUMAN NEUTROPHILS | TYROSINE PHOSPHORYLATION | INTERLEUKIN-10 RECEPTOR | GENE-EXPRESSION | KAPPA-B-ALPHA | IMMUNOLOGY | HUMAN MONOCYTES | MONONUCLEAR PHAGOCYTES | Protein Binding - genetics | Protein Biosynthesis | Interleukin-6 - antagonists & inhibitors | Humans | Tumor Necrosis Factor-alpha - genetics | Immunoglobulins - genetics | Lipopolysaccharides - antagonists & inhibitors | RNA, Messenger - metabolism | Suppressor of Cytokine Signaling Proteins | Repressor Proteins - antagonists & inhibitors | Antigens, CD - metabolism | Trans-Activators - physiology | Protein Tyrosine Phosphatases - antagonists & inhibitors | RNA, Messenger - biosynthesis | Protein Tyrosine Phosphatases - genetics | Inflammation Mediators - physiology | Glycoproteins - genetics | DNA-Binding Proteins - physiology | Protein Tyrosine Phosphatases - biosynthesis | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction - genetics | DNA - metabolism | Down-Regulation - genetics | Macrophages - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 2 | Repressor Proteins - biosynthesis | Up-Regulation - immunology | Interleukin-10 - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Adenoviruses, Human - genetics | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Antigens, CD - biosynthesis | Receptors, Cell Surface | Receptors, IgG - biosynthesis | Receptors, IgG - antagonists & inhibitors | Interleukin-10 - physiology | Signal Transduction - immunology | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Signaling Lymphocytic Activation Molecule Family Member 1 | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | RNA, Messenger - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type II | Trans-Activators - genetics | Inflammation Mediators - antagonists & inhibitors | Trans-Activators - biosynthesis | Immunoglobulins - biosynthesis | Macrophages - immunology | Inflammation Mediators - immunology | Receptors, Tumor Necrosis Factor - metabolism | Immune Sera - pharmacology | Proteins - physiology | Cells, Cultured | Glycoproteins - antagonists & inhibitors | Histocompatibility Antigens Class II - biosynthesis | Tissue Inhibitor of Metalloproteinase-1 - antagonists & inhibitors | Transcription Factors - antagonists & inhibitors | Transcription Factors - biosynthesis | Up-Regulation - genetics | DNA-Binding Proteins - genetics | DNA - antagonists & inhibitors | Glycoproteins - biosynthesis | Suppressor of Cytokine Signaling 3 Protein | Down-Regulation - immunology | Interleukin-6 - biosynthesis | Receptors, Tumor Necrosis Factor - biosynthesis | STAT3 Transcription Factor | Trans-Activators - antagonists & inhibitors | Genetic Vectors | DNA-Binding Proteins - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Expert Opinion on Drug Discovery, ISSN 1746-0441, 09/2013, Volume 8, Issue 9, pp. 1095 - 1116
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) have been on the increase during the past decade, due to the steady growth of the elderly and... 
acyl t-RNA synthase inhibitor | Clp protease inhibitor | methicillin-resistant Staphylococcus aureus | two-component system inhibitor | elongation factor G inhibitor | linezolid | antibacterial agents | combination therapy | daptomycin | vancomycin | β-lactamase inhibitor | antibacterial vaccine | dihydropteroate synthase inhibitor | peptidoglycan biosynthesis inhibitor | Pol IIIC inhibitor | electron transport inhibitor | RNA-polymerase inhibitor | phage therapy | peptide deformylase inhibitor | menaquinone biosynthesis inhibitor | Gram-positive pathogens | antibiotics | antimicrobial peptides | dihydrofolate reductase inhibitor | FAS II inhibitor | Linezolid | Peptide deformylase inhibitor | Daptomycin | Dihydropteroate synthase inhibitor | Vancomycin | Combination therapy | Antimicrobial peptides | Menaquinone biosynthesis inhibitor | Antibacterial vaccine | Dihydrofolate reductase inhibitor | Acyl t-RNA synthase inhibitor | Elongation factor G inhibitor | Antibacterial agents | Electron transport inhibitor | Peptidoglycan biosynthesis inhibitor | Antibiotics | Methicillin-resistant Staphylococcus aureus | Phage therapy | Two-component system inhibitor | SOFT-TISSUE INFECTIONS | INTENSIVE-CARE UNITS | beta-lactamase inhibitor | RESISTANT STAPHYLOCOCCUS-AUREUS | PHARMACOLOGY & PHARMACY | IN-VITRO ACTIVITY | TOREZOLID PHOSPHATE TR-701 | BRIDGED BICYCLIC MACROLIDE | DIHYDROFOLATE-REDUCTASE INHIBITOR | QUALITY-CONTROL RANGES | Anti-Bacterial Agents - therapeutic use | Animals | Bacterial Infections - drug therapy | Drug Resistance, Multiple, Bacterial | Humans | Drug Discovery | Methicillin-Resistant Staphylococcus aureus | elongation factor G (EF-G) inhibitor | peptide deformylase (PDF) inhibitor | methicillin-resistant Staphylococcus aureus (MRSA) | PolIIC inhibitor | β5 -lactamase inhibitor
Journal Article
Genes and Development, ISSN 0890-9369, 05/2013, Volume 27, Issue 10, pp. 1101 - 1114
Tumorigenesis results from dysregulation of oncogenes and tumor suppressors that influence cellular proliferation, differentiation, apoptosis, and/or... 
Huwe1 | c-Myc | Mule | Ras | p21 | Miz1 | DNA-DAMAGE | KERATINOCYTE GROWTH | DEVELOPMENTAL BIOLOGY | CELL BIOLOGY | BASE EXCISION-REPAIR | HUWE1 UBIQUITIN LIGASE | NEGATIVE REGULATION | GENETICS & HEREDITY | ARF TUMOR-SUPPRESSOR | DIFFERENTIATION | MIZ-1 | HUMAN CANCER | Protein Inhibitors of Activated STAT - deficiency | Tetradecanoylphorbol Acetate - pharmacology | 9,10-Dimethyl-1,2-benzanthracene - pharmacology | Male | Protein Inhibitors of Activated STAT - metabolism | Cyclin-Dependent Kinase Inhibitor p15 - biosynthesis | Oncogene Protein p21(ras) - metabolism | Cyclin-Dependent Kinase Inhibitor p16 | Oncogene Protein p21(ras) - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cell Transformation, Neoplastic - genetics | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Nuclear Proteins - deficiency | Protein Inhibitors of Activated STAT - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Nuclear Proteins - genetics | Protein Inhibitors of Activated STAT - antagonists & inhibitors | Skin Neoplasms - pathology | Cyclin-Dependent Kinase Inhibitor p21 - biosynthesis | Signal Transduction | Down-Regulation | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Skin Neoplasms - chemically induced | Proto-Oncogene Proteins c-myc - metabolism | Mice, Knockout | Skin Neoplasms - metabolism | Keratinocytes - pathology | Animals | Tumor Suppressor Protein p53 | Keratinocytes - drug effects | Keratinocytes - metabolism | Nuclear Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-myc - deficiency | Skin Neoplasms - genetics | Proto-Oncogene Proteins c-myc - antagonists & inhibitors | Ubiquitin-Protein Ligases - deficiency | Mice | Proto-Oncogene Proteins c-myc - genetics | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | Genes, ras | Ubiquitin-Protein Ligases - genetics | Oncogene Protein p21(ras) - genetics | Carcinogenesis | Ras genes | Analysis | Research Paper
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 1, pp. 41 - 51
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1591 - 1602
The mechanistic target of rapamycin (mTOR) is hyperactivated in many types of cancer, rendering it a compelling drug-target; however, the impact of mTOR... 
RAPAMYCIN | MEDICINE, RESEARCH & EXPERIMENTAL | PATHWAY | MUTATION | KINASE INHIBITORS | PROLIFERATION | CELL-GROWTH | PTEN-DEFICIENT | CANCER | CONTRIBUTES | Gas Chromatography-Mass Spectrometry | Humans | Glutamine - metabolism | Male | Neoplasm Proteins - antagonists & inhibitors | Purines - administration & dosage | Indoles - administration & dosage | Benzophenanthridines - therapeutic use | Glioblastoma - metabolism | Purines - therapeutic use | Neoplasm Proteins - genetics | Glutaminase - biosynthesis | Magnetic Resonance Spectroscopy | Benzophenanthridines - administration & dosage | Brain Neoplasms - drug therapy | Benzophenanthridines - pharmacology | Drug Synergism | Energy Metabolism | Signal Transduction - drug effects | Mice, Nude | Glioblastoma - pathology | Cell Line, Tumor | Indoles - therapeutic use | Mice | Mice, Inbred BALB C | Glioblastoma - drug therapy | Glutaminase - physiology | Neoplasm Proteins - physiology | Brain Neoplasms - pathology | Molecular Targeted Therapy | Brain Neoplasms - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Ketoglutaric Acids - metabolism | Neoplasm Proteins - biosynthesis | Purines - pharmacology | RNA, Small Interfering - pharmacology | Temporal Lobe - metabolism | Glutaminase - antagonists & inhibitors | Citric Acid Cycle | Xenograft Model Antitumor Assays | Rotarod Performance Test | Animals | Metabolome - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Glycolysis | Signal Transduction - physiology | Aged | Glutamic Acid - metabolism | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - physiology | Glutaminase - genetics | Pharmacology, Experimental | Oncology, Experimental | Glutamine metabolism | Research | Drug therapy | Drug resistance | Health aspects | Glioblastoma multiforme | Cancer | Medical research | Enzymes | Brain cancer | Neurosurgery | Glucose | Kinases | Metabolism | Carbon | Cancer therapies | Medicine | Cell growth | Brain research | Laboratory animals | Tumors | University graduates | Oncology
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7091, pp. 358 - 361
Journal Article