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Journal of Natural Products, ISSN 0163-3864, 01/2012, Volume 75, Issue 1, pp. 72 - 81
While natural products or their derivatives and mimics have contributed around 50% of current drugs, there has been no approach allowing front-loading of... 
IMPACT | CHEMISTRY, MEDICINAL | PERSPECTIVE | THERAPEUTIC TARGETS | PHARMACOLOGY & PHARMACY | BIOSYNTHETIC-ENZYMES | DISCOVERY | ALKALOIDS | PLANT SCIENCES
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 45, pp. 12616 - 12618
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 02/2012, Volume 53, Issue 2, pp. 311 - 320
Sterol 14α-demethylase (CYP51) that catalyzes the removal of the 14α-methyl group from the sterol nucleus is an essential enzyme in sterol biosynthesis, a... 
Sterol biosynthesis | Cytochrome P450 | Sterol biosynthetic enzymes | Inhibition | Trypanosoma brucei | Suicide substrates | Crystal structure | Trypanosoma cruzi | suicide substrates | sterol biosynthetic enzymes | crystal structure | inhibition | cytochrome P450 | sterol biosynthesis
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 07/2015, Volume 123, Issue 7, pp. 679 - 688
Journal Article
Plant Physiology, ISSN 0032-0889, 01/2018, Volume 176, Issue 1, pp. 582 - 595
Rice (Oryza sativa) endosperm is mainly occupied by homogeneous polygonal starch from inside to outside. However, morphologically different (heterogeneous)... 
ORYZA-SATIVA L | EXTENDER MUTATION | RESISTANT STARCH | MOLECULAR-STRUCTURES | PROTEIN-PROTEIN INTERACTIONS | STORAGE PROTEIN | SYNTHASE-I | HIGH-AMYLOSE RICE | BIOSYNTHETIC-ENZYMES | IMPROVES INDEXES | PLANT SCIENCES | Enzymes | Botanical research | Starch | Physiological aspects | Genetic aspects | Research | Gene expression | Rice | Analysis | Index Medicus
Journal Article
Plant Physiology, ISSN 0032-0889, 01/2018, Volume 176, Issue 1, pp. 566 - 581
The formation of normal starch granules in Arabidopsis (Arabidopsis thaliana) leaf chloroplasts requires STARCH SYNTHASE 4 (SS4). In plants lacking SS4,... 
GLYCOGEN-SYNTHASE | AMYLOSE SYNTHESIS | ARABIDOPSIS-THALIANA | MUTANTS | AMYLOPECTIN | METABOLISM | INITIATION | AMYLOPLASTS | COMPLEXES | BIOSYNTHETIC-ENZYMES | PLANT SCIENCES | Physiological aspects | Chloroplasts | Properties | Starch | Arabidopsis thaliana | Evaluation | Synthesis | Glycogen | Protein-protein interactions | Index Medicus
Journal Article
Crop Science, ISSN 0011-183X, 05/2018, Volume 58, Issue 3, pp. 1181 - 1191
Starch phosphorylase (Pho), especially the plastidial type, plays an important role in starch biosynthesis. The availability of a complete cassava (Manihot... 
ARABIDOPSIS LEAVES | AGRONOMY | ALPHA-GLUCAN PHOSPHORYLASE | CHLAMYDOMONAS-REINHARDTII | SUBCELLULAR-LOCALIZATION | PROTEIN-PROTEIN INTERACTIONS | SWEET-POTATO ROOTS | PISUM-SATIVUM-L | BIOCHEMICAL-CHARACTERIZATION | MOLECULAR-CLONING | BIOSYNTHETIC-ENZYMES
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 05/2014, Volume 62, Issue 19, pp. 4443 - 4453
Journal Article
Neuroscience, ISSN 0306-4522, 2013, Volume 236, pp. 298 - 312
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2013, Volume 69, Issue 38, pp. 8199 - 8204
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2017, Volume 114, Issue 27, pp. 7025 - 7030
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 11/2017, Volume 1863, Issue 11, pp. 2882 - 2890
Parkinson's disease (PD) is a degenerative disorder characterized by several motor symptoms including shaking, rigidity, slow movement and difficult walking,... 
Dopaminergic neurons | Dopamine transporter | Parkinson's disease | Biosynthetic enzymes | Drosophila | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | MUTANTS | PINK1 | BIOPHYSICS | NEUROTROPHIC FACTOR EXPRESSION | NEURONS | DYSFUNCTION | RECEPTORS | DOPA | MELANOGASTER | BRAIN | Tyrosine | Enzymes | Models | Analysis | Index Medicus
Journal Article
The Plant Cell, ISSN 1040-4651, 8/2009, Volume 21, Issue 8, pp. 2443 - 2457
Journal Article