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Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 11/2012, Volume 22, Issue 21, pp. 6688 - 6693
A series of dual CCR3/H antagonists based on a bispiperidine scaffold were discovered. Introduction of an acidic group overcame hERG liability. Bioavailability... 
Chemokine | hERG | Antagonist | CC-CHEMOKINE RECEPTOR-3 | SELECTIVE ANTAGONIST | CHEMISTRY, MEDICINAL | CHEMISTRY, ORGANIC | IDENTIFICATION | BIPIPERIDINE AMIDE COMPOUNDS | RIGID CYCLIC TEMPLATES | POTENT | ASTHMA | PART 1 | STABILIZED ACYCLIC SCAFFOLDS | DERIVATIVES
Journal Article
CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, ISSN 1367-6733, 07/2006, Volume 9, Issue 4, pp. 516 - 524
Journal Article
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