2010, 1. Aufl., Contributions to nephrology, ISBN 380559478X, Volume 166., viii, 195
Acute organ damage and the ensuing multiple organ failure are the result of a pathophysiological process involving various cytokines. Once activated, these...
Acute Disease | Filtration | Treatment | methods | therapy | Renal Replacement Therapy | Critical Care | Critical care medicine | Blood | Acute renal failure | Renal Dialysis | Kidney Failure, Acute | Clinical & internal medicine | Japan
Acute Disease | Filtration | Treatment | methods | therapy | Renal Replacement Therapy | Critical Care | Critical care medicine | Blood | Acute renal failure | Renal Dialysis | Kidney Failure, Acute | Clinical & internal medicine | Japan
Book
Journal of Chromatography A, ISSN 0021-9673, 2006, Volume 1101, Issue 1, pp. 1 - 24
Affinity chromatography has the reputation of a more expensive and less robust than other types of liquid chromatography. Furthermore, the technique is...
Affinity ligand | Microprotein scaffold | Rational design | Enzyme purification | Affinity chromatography | Protein purification | Dye-ligand | Proteomics | Ligand design | Bioinformatics | Triazine scaffold | Combinatorial library | rational design | affinity chromatography | microprotein scaffold | CHEMISTRY, ANALYTICAL | NEUTROPHIL ELASTASE INHIBITORS | proteomics | BETA-GALACTOSE DEHYDROGENASE | BIOCHEMICAL RESEARCH METHODS | protein purification | DNA-BINDING PROTEINS | triazine scaffold | RAY CRYSTAL-STRUCTURE | BOIDINII FORMATE DEHYDROGENASE | dye-ligand | enzyme purification | BIOMIMETIC DYE-LIGANDS | CIBACRON BLUE F3GA | BACTERIAL RECEPTOR DOMAIN | affinity ligand | bioinformatics | MITOCHONDRIAL MALATE-DEHYDROGENASE | LIVER ALCOHOL-DEHYDROGENASE | ligand design | combinatorial library | Blood Coagulation Factors - isolation & purification | Peptide Library | Proteins - isolation & purification | Glucose Oxidase - isolation & purification | Kallikreins - isolation & purification | Galactose Dehydrogenases - isolation & purification | Glycoproteins - isolation & purification | Prions - isolation & purification | Triazines - chemistry | Pancreatic Elastase - isolation & purification | Chromatography, Affinity - methods | Protein Structure, Tertiary | alpha 1-Antitrypsin - isolation & purification | Computational Biology - methods | Staphylococcal Protein A - isolation & purification | L-Lactate Dehydrogenase - isolation & purification | Aldehyde Oxidoreductases - isolation & purification | DNA-Binding Proteins - isolation & purification | Combinatorial Chemistry Techniques | SELEX Aptamer Technique | Ligands | Antibodies - isolation & purification | Bacterial Proteins - isolation & purification | Proinsulin - isolation & purification | Coloring Agents - chemistry | Peptides | Enzymes | Liquid chromatography
Affinity ligand | Microprotein scaffold | Rational design | Enzyme purification | Affinity chromatography | Protein purification | Dye-ligand | Proteomics | Ligand design | Bioinformatics | Triazine scaffold | Combinatorial library | rational design | affinity chromatography | microprotein scaffold | CHEMISTRY, ANALYTICAL | NEUTROPHIL ELASTASE INHIBITORS | proteomics | BETA-GALACTOSE DEHYDROGENASE | BIOCHEMICAL RESEARCH METHODS | protein purification | DNA-BINDING PROTEINS | triazine scaffold | RAY CRYSTAL-STRUCTURE | BOIDINII FORMATE DEHYDROGENASE | dye-ligand | enzyme purification | BIOMIMETIC DYE-LIGANDS | CIBACRON BLUE F3GA | BACTERIAL RECEPTOR DOMAIN | affinity ligand | bioinformatics | MITOCHONDRIAL MALATE-DEHYDROGENASE | LIVER ALCOHOL-DEHYDROGENASE | ligand design | combinatorial library | Blood Coagulation Factors - isolation & purification | Peptide Library | Proteins - isolation & purification | Glucose Oxidase - isolation & purification | Kallikreins - isolation & purification | Galactose Dehydrogenases - isolation & purification | Glycoproteins - isolation & purification | Prions - isolation & purification | Triazines - chemistry | Pancreatic Elastase - isolation & purification | Chromatography, Affinity - methods | Protein Structure, Tertiary | alpha 1-Antitrypsin - isolation & purification | Computational Biology - methods | Staphylococcal Protein A - isolation & purification | L-Lactate Dehydrogenase - isolation & purification | Aldehyde Oxidoreductases - isolation & purification | DNA-Binding Proteins - isolation & purification | Combinatorial Chemistry Techniques | SELEX Aptamer Technique | Ligands | Antibodies - isolation & purification | Bacterial Proteins - isolation & purification | Proinsulin - isolation & purification | Coloring Agents - chemistry | Peptides | Enzymes | Liquid chromatography
Journal Article
ACS Nano, ISSN 1936-0851, 03/2015, Volume 9, Issue 3, pp. 2321 - 2327
Microvesicles (MVs) are an increasingly important source for biomarker discovery and clinical diagnostics. The small size of MVs and their presence in complex...
nanotechnology | microvesicles | microfluidics | nanoparticle separation | acoustic wave | PARTICLES | VESICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | LARGE ONCOSOMES | MICROPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | WAVES | THERAPY | EXOSOMES | RED-BLOOD-CELLS | SEPARATION | Transducers | Humans | Cell Fractionation - methods | Cell Line, Tumor | Erythrocytes - cytology | Acoustics | Exosomes | Cell-Derived Microparticles | Cell Fractionation - instrumentation | Separation | Electronics | Tools | Nanostructure | Density | Ultrasound | Nanoparticle separation | Microvesicles | Acoustic wave | Nanotechnology | Microfluidics
nanotechnology | microvesicles | microfluidics | nanoparticle separation | acoustic wave | PARTICLES | VESICLES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | LARGE ONCOSOMES | MICROPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | WAVES | THERAPY | EXOSOMES | RED-BLOOD-CELLS | SEPARATION | Transducers | Humans | Cell Fractionation - methods | Cell Line, Tumor | Erythrocytes - cytology | Acoustics | Exosomes | Cell-Derived Microparticles | Cell Fractionation - instrumentation | Separation | Electronics | Tools | Nanostructure | Density | Ultrasound | Nanoparticle separation | Microvesicles | Acoustic wave | Nanotechnology | Microfluidics
Journal Article
Journal of Periodontal Research, ISSN 0022-3484, 02/2013, Volume 48, Issue 1, pp. 30 - 36
Background and Objective: There is a bidirectional relationship between periodontal disease and type‐2 diabetes mellitus (DM). Inflammatory mediators may...
diabetes | periodontal microbiota | subgingival plaque | Subgingival plaque | Periodontal microbiota | Diabetes | GLYCEMIC CONTROL | PORPHYROMONAS-GINGIVALIS | ACTINOMYCETEMCOMITANS | PREVALENCE | EIKENELLA-CORRODENS | PLAQUE | INDIVIDUALS | DENTISTRY, ORAL SURGERY & MEDICINE | DISEASE | CAPNOCYTOPHAGA SPP | PATHOGENS | Neisseria - isolation & purification | Eubacterium - isolation & purification | Diabetes Mellitus, Type 2 - microbiology | Humans | RNA, Ribosomal, 16S - analysis | Male | Selenomonas - isolation & purification | Biodiversity | Eikenella - isolation & purification | Chronic Periodontitis - microbiology | Streptococcus - isolation & purification | Bacteria - classification | Adult | Female | Periodontal Pocket - microbiology | Porphyromonas - isolation & purification | Veillonella - isolation & purification | Actinomyces - isolation & purification | Gram-Negative Anaerobic Bacteria - isolation & purification | Treponema - isolation & purification | Capnocytophaga - isolation & purification | Gemella - isolation & purification | Chronic Periodontitis - classification | RNA, Bacterial - analysis | Bacteria - isolation & purification | Diabetes Mellitus, Type 2 - blood | Periodontal Attachment Loss - microbiology | Actinobacillus - isolation & purification | Biofilms - classification | Gingiva - microbiology | Bacteroides - isolation & purification | Fusobacterium - isolation & purification
diabetes | periodontal microbiota | subgingival plaque | Subgingival plaque | Periodontal microbiota | Diabetes | GLYCEMIC CONTROL | PORPHYROMONAS-GINGIVALIS | ACTINOMYCETEMCOMITANS | PREVALENCE | EIKENELLA-CORRODENS | PLAQUE | INDIVIDUALS | DENTISTRY, ORAL SURGERY & MEDICINE | DISEASE | CAPNOCYTOPHAGA SPP | PATHOGENS | Neisseria - isolation & purification | Eubacterium - isolation & purification | Diabetes Mellitus, Type 2 - microbiology | Humans | RNA, Ribosomal, 16S - analysis | Male | Selenomonas - isolation & purification | Biodiversity | Eikenella - isolation & purification | Chronic Periodontitis - microbiology | Streptococcus - isolation & purification | Bacteria - classification | Adult | Female | Periodontal Pocket - microbiology | Porphyromonas - isolation & purification | Veillonella - isolation & purification | Actinomyces - isolation & purification | Gram-Negative Anaerobic Bacteria - isolation & purification | Treponema - isolation & purification | Capnocytophaga - isolation & purification | Gemella - isolation & purification | Chronic Periodontitis - classification | RNA, Bacterial - analysis | Bacteria - isolation & purification | Diabetes Mellitus, Type 2 - blood | Periodontal Attachment Loss - microbiology | Actinobacillus - isolation & purification | Biofilms - classification | Gingiva - microbiology | Bacteroides - isolation & purification | Fusobacterium - isolation & purification
Journal Article
Critical Care, ISSN 1364-8535, 12/2018, Volume 22, Issue 1, pp. 357 - 3
Journal Article
Critical Care Medicine, ISSN 0090-3493, 09/2013, Volume 41, Issue 9, pp. 2209 - 2220
OBJECTIVES:Although blood purification improves outcomes in animal studies of sepsis, results of clinical trials have been mixed. We conducted a systematic...
blood purification | mortality | metaanalysis | cytokines | inflammation | sepsis | UNITED-STATES | ACUTE KIDNEY INJURY | B-IMMOBILIZED FIBER | CONTINUOUS HEMODIAFILTRATION | meta-analysis | ORGAN FAILURE | HEMOPERFUSION | SEPTIC PATIENTS | REMOVAL | HIGH-VOLUME HEMOFILTRATION | RENAL REPLACEMENT THERAPY | CRITICAL CARE MEDICINE | Sorption Detoxification - adverse effects | Humans | Sepsis - blood | Sorption Detoxification - methods | Cause of Death | Randomized Controlled Trials as Topic | Sepsis - mortality
blood purification | mortality | metaanalysis | cytokines | inflammation | sepsis | UNITED-STATES | ACUTE KIDNEY INJURY | B-IMMOBILIZED FIBER | CONTINUOUS HEMODIAFILTRATION | meta-analysis | ORGAN FAILURE | HEMOPERFUSION | SEPTIC PATIENTS | REMOVAL | HIGH-VOLUME HEMOFILTRATION | RENAL REPLACEMENT THERAPY | CRITICAL CARE MEDICINE | Sorption Detoxification - adverse effects | Humans | Sepsis - blood | Sorption Detoxification - methods | Cause of Death | Randomized Controlled Trials as Topic | Sepsis - mortality
Journal Article
Circulation, ISSN 0009-7322, 08/2017, Volume 136, Issue 7, pp. 618 - 627
BACKGROUND:Exposure to ambient particulate matter (PM) is associated with a number of adverse health outcomes, but potential mechanisms are largely unknown....
Metabolomics | Stress, oxidative | Hormones | Randomized controlled trial | Particulate matter | stress | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | ASSOCIATIONS | hormones | LONG-TERM EXPOSURE | BLOOD-PRESSURE | randomized controlled trial | SYSTEMIC INFLAMMATION | particulate matter | POLLUTION | metabolomics | LYSOPHOSPHATIDYLCHOLINE | HEART-RATE-VARIABILITY | PM2.5 | oxidative | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | Particulate Matter - toxicity | Gas Chromatography-Mass Spectrometry | Double-Blind Method | Humans | Cortisone - blood | Male | Biomarkers - blood | Chromatography, High Pressure Liquid | Environmental Exposure | Hypertension - etiology | Cross-Over Studies | Young Adult | Particulate Matter - analysis | China | Epinephrine - blood | Lipid Metabolism - drug effects | Female | Oxidative Stress - drug effects | Air Filters | Hormones - blood | Hydrocortisone - blood
Metabolomics | Stress, oxidative | Hormones | Randomized controlled trial | Particulate matter | stress | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | ASSOCIATIONS | hormones | LONG-TERM EXPOSURE | BLOOD-PRESSURE | randomized controlled trial | SYSTEMIC INFLAMMATION | particulate matter | POLLUTION | metabolomics | LYSOPHOSPHATIDYLCHOLINE | HEART-RATE-VARIABILITY | PM2.5 | oxidative | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | Particulate Matter - toxicity | Gas Chromatography-Mass Spectrometry | Double-Blind Method | Humans | Cortisone - blood | Male | Biomarkers - blood | Chromatography, High Pressure Liquid | Environmental Exposure | Hypertension - etiology | Cross-Over Studies | Young Adult | Particulate Matter - analysis | China | Epinephrine - blood | Lipid Metabolism - drug effects | Female | Oxidative Stress - drug effects | Air Filters | Hormones - blood | Hydrocortisone - blood
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 09/2017, Volume 1063, pp. 50 - 59
MK-1293 is a newly approved follow-on/biosimilar insulin glargine for the treatment of Type 1 and Type 2 diabetics. To support pivotal clinical studies during...
Insulin glargine and its active metabolites M1 and M2 | Biosimilar clinical studies | Hybrid method | LC–MS/MS | Immunoaffinity purification (IAP) | Insulin Glargine - blood | Reproducibility of Results | Insulin Glargine - metabolism | Drug Stability | Humans | Sensitivity and Specificity | Least-Squares Analysis | Diabetes Mellitus, Type 1 | Insulin Glargine - chemistry | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Medicine, Experimental | Clinical trials | Medical research | Metabolites | Insulin | Biological products | Ionization | Liquid chromatography | Mass spectrometry
Insulin glargine and its active metabolites M1 and M2 | Biosimilar clinical studies | Hybrid method | LC–MS/MS | Immunoaffinity purification (IAP) | Insulin Glargine - blood | Reproducibility of Results | Insulin Glargine - metabolism | Drug Stability | Humans | Sensitivity and Specificity | Least-Squares Analysis | Diabetes Mellitus, Type 1 | Insulin Glargine - chemistry | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Medicine, Experimental | Clinical trials | Medical research | Metabolites | Insulin | Biological products | Ionization | Liquid chromatography | Mass spectrometry
Journal Article
Biotechnology Advances, ISSN 0734-9750, 11/2011, Volume 29, Issue 6, pp. 940 - 948
Lactulose a “bifidus factor” is composed of galactose and fructose, which can be produced by the isomerization of lactose. It is a prebiotic carbohydrate which...
Purification | Applications | Mechanism of action | Lactulose | Analysis | Production | CHROMATOGRAPHIC DETERMINATION | OBSTRUCTIVE-JAUNDICE | SPECTROPHOTOMETRIC METHOD | QUANTITATIVE-DETERMINATION | YEAST-CELLS | LIQUID-CHROMATOGRAPHY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SPECTROMETRY METHOD | LACTOSE ISOMERIZATION | AMPEROMETRIC DETECTION | INTESTINAL PERMEABILITY | Biotechnology - methods | Lactulose - chemistry | Lactulose - metabolism | Lactulose - isolation & purification | Usage | Galactose | Blood sugar | Production processes | Fructose
Purification | Applications | Mechanism of action | Lactulose | Analysis | Production | CHROMATOGRAPHIC DETERMINATION | OBSTRUCTIVE-JAUNDICE | SPECTROPHOTOMETRIC METHOD | QUANTITATIVE-DETERMINATION | YEAST-CELLS | LIQUID-CHROMATOGRAPHY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SPECTROMETRY METHOD | LACTOSE ISOMERIZATION | AMPEROMETRIC DETECTION | INTESTINAL PERMEABILITY | Biotechnology - methods | Lactulose - chemistry | Lactulose - metabolism | Lactulose - isolation & purification | Usage | Galactose | Blood sugar | Production processes | Fructose
Journal Article
Critical Care, ISSN 1364-8535, 02/2011, Volume 15, Issue 1, pp. 205 - 205
Sepsis is the primary cause of death in the intensive care unit. Extracorporeal blood purification therapies have been proposed for patients with sepsis in...
HYPERDYNAMIC SEPTIC SHOCK | INFLAMMATORY RESPONSE SYNDROME | CONTINUOUS VENOVENOUS HEMOFILTRATION | HIGH-VOLUME HEMOFILTRATION | COUPLED PLASMA FILTRATION | ACUTE-RENAL-FAILURE | RANDOMIZED CONTROLLED-TRIAL | SHORT-TERM SURVIVAL | AUREUS-INDUCED SEPTICEMIA | HIGH CUTOFF | CRITICAL CARE MEDICINE | Hemofiltration - instrumentation | Animals | Humans | Sepsis - therapy | Hemofiltration - methods | Sepsis - blood | Biomarkers - blood | Sepsis - physiopathology | Review
HYPERDYNAMIC SEPTIC SHOCK | INFLAMMATORY RESPONSE SYNDROME | CONTINUOUS VENOVENOUS HEMOFILTRATION | HIGH-VOLUME HEMOFILTRATION | COUPLED PLASMA FILTRATION | ACUTE-RENAL-FAILURE | RANDOMIZED CONTROLLED-TRIAL | SHORT-TERM SURVIVAL | AUREUS-INDUCED SEPTICEMIA | HIGH CUTOFF | CRITICAL CARE MEDICINE | Hemofiltration - instrumentation | Animals | Humans | Sepsis - therapy | Hemofiltration - methods | Sepsis - blood | Biomarkers - blood | Sepsis - physiopathology | Review
Journal Article
Medicine, ISSN 0025-7974, 03/2019, Volume 98, Issue 12, p. e14873
Background: The incidence of acute pancreatitis (AP) is rising around the world, thus further increasing the burden on healthcare services. Approximately 20%...
MEDICINE, GENERAL & INTERNAL | MANAGEMENT | severe acute pancreatitis | continuous blood purification | organ failure | GUIDELINES | meta-analysis | HIGH-VOLUME HEMOFILTRATION | IMPROVEMENT | NUTRITION | DYSFUNCTION | Usage | Care and treatment | Analysis | Pancreatitis | Research | Detoxification therapy (Alternative medicine) | Prevalence studies (Epidemiology) | Meta-analysis
MEDICINE, GENERAL & INTERNAL | MANAGEMENT | severe acute pancreatitis | continuous blood purification | organ failure | GUIDELINES | meta-analysis | HIGH-VOLUME HEMOFILTRATION | IMPROVEMENT | NUTRITION | DYSFUNCTION | Usage | Care and treatment | Analysis | Pancreatitis | Research | Detoxification therapy (Alternative medicine) | Prevalence studies (Epidemiology) | Meta-analysis
Journal Article
Vox Sanguinis, ISSN 0042-9007, 07/2014, Volume 107, Issue 1, pp. 26 - 36
Background and objectives Activated clotting factor FXI (FXIa) has been postulated to play a significant role in thromboembolic events potentially associated...
thromboembolic events | procoagulant activity | Factor XIa | intravenous immunoglobulin | Privigen | Intravenous immunoglobulin | Procoagulant activity | Thromboembolic events | SAFETY | PRODUCT | IMMUNOGLOBULIN | IGG | Privigen (R) | HEMATOLOGY | Thrombin - biosynthesis | Enzyme-Linked Immunosorbent Assay | Thromboembolism - prevention & control | Humans | Plasma - chemistry | Factor XIa - isolation & purification | Immunoglobulins, Intravenous - adverse effects | Blood Coagulation Tests | Thromboembolism - etiology | Thrombin | Thromboembolism | Fatty acids | Analysis | Production processes | Plasma | Immunoglobulins | Hematology | Coagulation
thromboembolic events | procoagulant activity | Factor XIa | intravenous immunoglobulin | Privigen | Intravenous immunoglobulin | Procoagulant activity | Thromboembolic events | SAFETY | PRODUCT | IMMUNOGLOBULIN | IGG | Privigen (R) | HEMATOLOGY | Thrombin - biosynthesis | Enzyme-Linked Immunosorbent Assay | Thromboembolism - prevention & control | Humans | Plasma - chemistry | Factor XIa - isolation & purification | Immunoglobulins, Intravenous - adverse effects | Blood Coagulation Tests | Thromboembolism - etiology | Thrombin | Thromboembolism | Fatty acids | Analysis | Production processes | Plasma | Immunoglobulins | Hematology | Coagulation
Journal Article
Diabetes, ISSN 0012-1797, 12/2010, Volume 59, Issue 12, pp. 3049 - 3057
OBJECTIVE Obesity alters gut microbiota ecology and associates with low-grade inflammation in humans. Roux-en-Y gastric bypass (RYGB) surgery is one of the...
LEPTIN | MICROFLORA | GASTRIC BYPASS-SURGERY | PEPTIDE-YY | OBESITY | ENERGY | DIET | ENDOCRINOLOGY & METABOLISM | ENDOTOXEMIA | RESTRICTION | INSULIN SENSITIVITY | Adaptation, Physiological | Pediococcus - isolation & purification | Humans | Male | Thinness - microbiology | Bifidobacterium - isolation & purification | Clostridium - isolation & purification | Obesity - microbiology | Leuconostoc - isolation & purification | Feces - microbiology | Polymerase Chain Reaction | Female | Starvation - microbiology | Bariatric Surgery | Inflammation - microbiology | Bifidobacterium - genetics | Clostridium - genetics | DNA Primers | Inflammation - etiology | Bacteroides - genetics | Escherichia coli - isolation & purification | Weight Loss - physiology | Blood Glucose - metabolism | Bacteroides - isolation & purification | Lactobacillus - isolation & purification | Inflammation - physiopathology | Obesity | Care and treatment | Microbiota (Symbiotic organisms) | Leptin | Analysis | Surgery | Patient outcomes | Weight loss | Physiological aspects | Inflammation | Research | Obesity Studies
LEPTIN | MICROFLORA | GASTRIC BYPASS-SURGERY | PEPTIDE-YY | OBESITY | ENERGY | DIET | ENDOCRINOLOGY & METABOLISM | ENDOTOXEMIA | RESTRICTION | INSULIN SENSITIVITY | Adaptation, Physiological | Pediococcus - isolation & purification | Humans | Male | Thinness - microbiology | Bifidobacterium - isolation & purification | Clostridium - isolation & purification | Obesity - microbiology | Leuconostoc - isolation & purification | Feces - microbiology | Polymerase Chain Reaction | Female | Starvation - microbiology | Bariatric Surgery | Inflammation - microbiology | Bifidobacterium - genetics | Clostridium - genetics | DNA Primers | Inflammation - etiology | Bacteroides - genetics | Escherichia coli - isolation & purification | Weight Loss - physiology | Blood Glucose - metabolism | Bacteroides - isolation & purification | Lactobacillus - isolation & purification | Inflammation - physiopathology | Obesity | Care and treatment | Microbiota (Symbiotic organisms) | Leptin | Analysis | Surgery | Patient outcomes | Weight loss | Physiological aspects | Inflammation | Research | Obesity Studies
Journal Article