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blood-retina barrier (116) 116
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Experimental Eye Research, ISSN 0014-4835, 2009, Volume 89, Issue 1, pp. 4 - 15
Disruption of the blood–retina barrier (BRB) is an early phenomenon in preclinical diabetic retinopathy (PCDR). Two vascular permeability pathways may be... 
blood–brain barrier | streptozotocin | plasmalemma vesicle-associated protein | blood–retina barrier | tight junctions | real-time PCR | diabetic retinopathy | vascular permeability | diabetes | caveolae | blood-brain barrier | blood-retina barrier | DIFFERENTIAL EXPRESSION | VEGF-A | BETA-CATENIN | BRAIN-BARRIER | TIGHT JUNCTION STRANDS | ANTIGEN PAL-E | OPHTHALMOLOGY | CELL-ADHESION MOLECULES | GROWTH-FACTOR | ALDOSE REDUCTASE | VASCULAR ENDOTHELIAL-CADHERIN | Retina - metabolism | Rats, Wistar | Tight Junctions - genetics | Diabetes Mellitus, Experimental - genetics | Vesicular Transport Proteins - biosynthesis | Adherens Junctions - metabolism | Capillary Permeability - genetics | Cattle | Eye Proteins - genetics | Diabetes Mellitus, Experimental - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Adherens Junctions - genetics | Tight Junctions - metabolism | Blood-Retinal Barrier - physiology | Endothelial Cells - metabolism | Pericytes - metabolism | RNA, Messenger - genetics | Vesicular Transport Proteins - genetics | Cells, Cultured | Gene Expression Regulation - physiology | Rats | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Gene Expression Regulation - drug effects | Animals | Databases, Nucleic Acid | Eye Proteins - biosynthesis | Immunohistochemistry | Proteins | Diabetic retinopathy | Medical colleges | Messenger RNA | Genetic research | Ophthalmology | Permeability | Gene expression | Vascular endothelial growth factor | Endothelium | Retinopathy | Caveolae | Tight junctions | Transcription | Diabetes mellitus | pericytes | Retina | Endothelial cells | Eye | Polymerase chain reaction | caveolin-1 | Vesicles | Plasma membranes | Capillaries | Protein transport
Journal Article
Experimental Eye Research, ISSN 0014-4835, 2009, Volume 89, Issue 1, pp. 71 - 78
3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) are frequently used lipid-lowering drugs in type 2 diabetes. Recent emerging... 
blood–retina barrier | statin | diabetic retinopathy | inflammation | tight junction | blood-retina barrier | INTERCELLULAR-ADHESION MOLECULE-1 | EPITHELIUM-DERIVED FACTOR | MACULAR EDEMA | IN-VIVO | OPHTHALMOLOGY | RETINOPATHY | LEUKOCYTE ADHESION | TNF-ALPHA | MONOCYTE CHEMOTACTIC PROTEIN-1 | SIMVASTATIN | ENDOTHELIAL GROWTH-FACTOR | Tumor Necrosis Factor-alpha - metabolism | Retina - metabolism | Lovastatin - pharmacology | Male | NF-kappa B - metabolism | Diabetes Mellitus, Type 2 - metabolism | Blood-Retinal Barrier - drug effects | Diabetic Retinopathy - physiopathology | Lipids - blood | Inflammation Mediators - metabolism | Diabetes Mellitus, Experimental - metabolism | Diabetes Mellitus, Experimental - physiopathology | Retinal Pigment Epithelium - drug effects | Tight Junctions - drug effects | Lovastatin - therapeutic use | Drug Evaluation, Preclinical - methods | Mice, Inbred C57BL | Cells, Cultured | Diabetic Retinopathy - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Diabetic Retinopathy - prevention & control | Intercellular Adhesion Molecule-1 - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Mice | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Type 2 diabetes | Diabetic retinopathy | Inflammation | Ophthalmology | Permeability | Statins
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 04/2017, Volume 58, Issue 4, pp. 678 - 681
P-glycoprotein (ABCB1) is expressed at the blood-retina barrier (BRB), where it may control distribution of drugs from blood to the retina and thereby... 
eye | blood-brain barrier | P-glycoprotein | BRAIN-BARRIER | INHIBITION | blood-retina barrier | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | CARRIER
Journal Article
Neuron, ISSN 0896-6273, 12/2017, Volume 96, Issue 5, pp. 1055 - 1069.e6
Coordinating angiogenesis with acquisition of tissue-specific properties in endothelial cells is essential for vascular function. In the retina, endothelial... 
Wnt/β-catenin signaling | Caveolin-1 | angiogenesis | blood-retina barrier | Frizzled-4 | transcytosis | vascular pruning | Claudin-5 | Norrin | Apcdd1 | tight junction | Occludin | BRAIN-BARRIER | FENESTRATED ENDOTHELIA | ANGIOGENESIS | ENDOTHELIAL-CELLS | CNS | CENTRAL-NERVOUS-SYSTEM | DIFFERENTIATION | NEUROSCIENCES | NORRIN | BREAKDOWN | INFILTRATION | SOXF Transcription Factors - metabolism | Pericytes - physiology | Retinal Vessels - physiology | Membrane Proteins - physiology | Extracellular Matrix - physiology | Neurons - physiology | HMGB Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Endothelial Cells - physiology | Tight Junction Proteins - metabolism | Blood-Retinal Barrier - physiology | Endothelial Cells - metabolism | Membrane Proteins - genetics | Neuroglia - physiology | Mice, Transgenic | Intracellular Signaling Peptides and Proteins - biosynthesis | Mutation - genetics | Mice, Knockout | Extracellular Matrix - ultrastructure | Membrane Proteins - biosynthesis | Animals | Wnt Signaling Pathway - drug effects | Endothelium - metabolism | Mice | Intracellular Signaling Peptides and Proteins - physiology | Endothelium - physiology | Neurosciences | Permeability | Cells | Endothelium | Wnt protein | Maturation | Tight junctions | Blood vessels | Retina | Nervous system | Hybridization | Remodeling | Endothelial cells | Angiogenesis | β-catenin | Signaling | Blood-brain barrier | Cellular biology | Pruning | LRP5 protein | Ligands
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 04/2017, Volume 58, Issue 4, pp. 678 - 681
P-glycoprotein (ABCB1) is expressed at the blood-retina barrier (BRB), where it may control distribution of drugs from blood to the retina and thereby... 
Eye | P-glycoprotein | Blood-retina barrier | Blood-brain barrier | PET | Index Medicus
Journal Article
Journal of Drug Targeting, ISSN 1061-186X, 03/2019, Volume 27, Issue 3, pp. 338 - 346
Because the blood-brain barrier (BBB) is an obstacle for drug-delivery, carrier systems such as polybutylcyanoacrylate (PBCA) nanoparticles (NPs) have been... 
polybutylcyanoacrylate nanoparticles | particle size | in vivo imaging | surfactants | Blood-brain barrier | blood-retina barrier | ICON | pharmacokinetic of nanoparticles | zeta-potential | DRUG | VIVO | DOXORUBICIN | CNS | RESTORATION | BRAIN-BARRIER | IN-VITRO | TRANSPORT | CONFOCAL NEUROIMAGING ICON | GANGLION-CELLS | PHARMACOLOGY & PHARMACY
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 2015, Volume 56, Issue 5, pp. 2971 - 2979
Journal Article
Expert Opinion on Drug Delivery, ISSN 1742-5247, 05/2008, Volume 5, Issue 5, pp. 567 - 581
Journal Article
Diabetes & Vascular Disease Research, ISSN 1479-1641, 5/2017, Volume 14, Issue 3, pp. 200 - 213
Using a porcine model of diabetes mellitus and hypercholesterolaemia, we previously showed that diabetes mellitus and hypercholesterolaemia is associated with... 
blood-brain barrier | endothelium | Blood-retina barrier | occludin | retina | blood vessels | cholesterol | tight junctions | diabetes | claudin-5 | lipoprotein-associated phospholipase-A
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 11/2012, Volume 32, Issue 11, pp. 1989 - 2001
Uptake1 and uptake2 transporters are involved in the extracellular clearance of biogenic amine neurotransmitters at synaptic clefts. We looked for them at the... 
blood-brain barrier | organic cation transporters | uptake transporters | dopamine | blood-retina barrier | neurovascular unit | LOCALIZATION | SEROTONIN TRANSPORTER | MICROVESSEL ENDOTHELIAL-CELLS | DRUG-METABOLIZING-ENZYMES | NEUROSCIENCES | MEMBRANE MONOAMINE TRANSPORTER | ENDOCRINOLOGY & METABOLISM | SENSITIVE NOREPINEPHRINE TRANSPORTER | RAT-BRAIN | HEMATOLOGY | EXPRESSION | Immunohistochemistry | Retina - metabolism | Cerebral Cortex - blood supply | Neurotransmitter Agents - metabolism | Male | Immunochemistry | Cerebral Cortex - metabolism | Blood-Brain Barrier - metabolism | Tissue Distribution | Microscopy, Confocal | RNA - biosynthesis | Kidney - metabolism | Algorithms | Animals | Carrier Proteins - metabolism | Serotonin - metabolism | Polymerase Chain Reaction | Biogenic Amines - metabolism | Membrane Transport Proteins - metabolism | Mice | Neurons - metabolism | Capillaries - metabolism | Dopamine - metabolism | Neuroimaging | Polymerase chain reaction | Brain | Neurotransmitters | Serotonin transporter | Blood-brain barrier | Cerebral blood flow | Perfusion | Retina | Xenobiotics | Biogenic amines | Synaptic cleft | RNA | Genomics | Cerebral Cortex | Kidney | Life Sciences | Biogenic Amines | Capillaries | Carrier Proteins | Dopamine | Serotonin | Neurons | Biochemistry, Molecular Biology | Neurotransmitter Agents | Membrane Transport Proteins | Blood-Brain Barrier | blood–brain barrier | blood–retina barrier | Original
Journal Article