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female (357) 357
bone morphogenetic protein-15 (343) 343
animals (313) 313
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humans (213) 213
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reproductive biology (175) 175
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endocrinology & metabolism (98) 98
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granulosa-cells (83) 83
bmp15 (79) 79
gene expression (77) 77
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oocytes - metabolism (73) 73
oocyte (70) 70
oocytes (70) 70
bone morphogenetic protein 15 - genetics (69) 69
oocytes - physiology (68) 68
sheep (67) 67
mutation (65) 65
expression (63) 63
folliculogenesis (62) 62
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research (61) 61
ovarian follicle - metabolism (60) 60
bone morphogenetic protein 15 - metabolism (58) 58
oocytes - cytology (57) 57
growth differentiation factor 9 - metabolism (56) 56
ovarian follicle - physiology (56) 56
cells, cultured (55) 55
endocrine system (54) 54
intercellular signaling peptides and proteins - genetics (53) 53
biochemistry & molecular biology (51) 51
follicular development (51) 51
premature ovarian failure (51) 51
gdf9 (49) 49
granulosa cells - metabolism (49) 49
messenger-ribonucleic-acid (49) 49
rna, messenger - metabolism (49) 49
in-vitro (47) 47
ovarian follicle - growth & development (47) 47
anti-mullerian hormone (46) 46
adult (45) 45
growth factors (45) 45
ovarian follicle - cytology (45) 45
gene-expression (44) 44
genes (43) 43
ovary - metabolism (43) 43
primary ovarian insufficiency - genetics (43) 43
rats (43) 43
genetic aspects (42) 42
genetics & heredity (42) 42
agriculture, dairy & animal science (41) 41
analysis (41) 41
differentiation factor-9 (41) 41
growth (40) 40
male (40) 40
granulosa cells (38) 38
proteins (38) 38
oocyte maturation (37) 37
ovulation (37) 37
physiological aspects (37) 37
mutations (36) 36
gene (35) 35
signal transduction (35) 35
follicles (34) 34
oocytes - drug effects (34) 34
pregnancy (34) 34
growth-differentiation-factor-9 cooperate (32) 32
bmp15 gene (31) 31
in-vitro maturation (31) 31
intercellular signaling peptides and proteins - metabolism (31) 31
mouse oocytes (31) 31
ovulation rate (31) 31
transforming growth factors (31) 31
cattle (30) 30
cumulus cells (30) 30
granulosa cells - drug effects (30) 30
bmp-15 (29) 29
fertility (29) 29
follicle (29) 29
gene expression regulation, developmental (29) 29
genetic research (29) 29
ovarian follicular development (29) 29
reproduction (29) 29
synergistic roles (29) 29
infertility (28) 28
messenger-rna (28) 28
ovarian follicle - drug effects (28) 28
article (27) 27
differentiation (27) 27
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1. Full Text Bone morphogenetic protein-15: Identification of target cells and biological functions
by Otsuka, Fumio and Yao, Zuxu and Lee, Taek-Hoo and Yamamoto, Shin and Erickson, Gregory F and Shimasaki, Shunichi
Journal of Biological Chemistry, ISSN 0021-9258, 12/2000, Volume 275, Issue 50, pp. 39523 - 39528
In developing ovarian follicles, the regulation of cell proliferation and differentiation is tightly coordinated, Precisely how this coordination is achieved... 
GROWTH FACTOR-BETA | AROMATASE-ACTIVITY | INDUCED DIFFERENTIATION | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOLLICLE-STIMULATING-HORMONE | RAT GRANULOSA-CELLS | HOMOLOG GDF-9B | FOLLICULOGENESIS | BOVINE ACTIVIN | ESTROUS-CYCLE | Immunohistochemistry | Humans | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Dose-Response Relationship, Drug | In Situ Hybridization | Growth Differentiation Factor 9 | Cell Division | Female | Cell Differentiation | Ovarian Follicle - metabolism | Recombinant Proteins - metabolism | Cell Line | Follicle Stimulating Hormone - metabolism | Oocytes - metabolism | Electrophoresis, Polyacrylamide Gel | Intercellular Signaling Peptides and Proteins | Cells, Cultured | Glutathione Transferase - metabolism | Rats | Reverse Transcriptase Polymerase Chain Reaction | Plasmids - metabolism | Rats, Sprague-Dawley | Blotting, Western | Bone Morphogenetic Protein 15 | Animals | Mitosis - drug effects | Growth Substances - physiology | Progesterone - metabolism | Sheep | Granulosa Cells | Growth Substances - metabolism
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2. Full Text Molecular Basis of Bone Morphogenetic Protein-15 Signaling in Granulosa Cells
by R. Kelly Moore and Fumio Otsuka and Shunichi Shimasaki
Journal of Biological Chemistry, ISSN 0021-9258, 01/2003, Volume 278, Issue 1, pp. 304 - 310
Bone morphogenetic protein-15 (BMP-15), an oocyte growth factor belonging to the transforming growth factor-β superfamily, has recently been shown to be... 
I RECEPTORS | PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | GROWTH-DIFFERENTIATION FACTOR-9 | OOCYTES | OSTEOGENIC PROTEIN-1 | BETA SUPERFAMILY | IDENTIFICATION | EXPRESSION | ACTIVIN | Presenilin-1 | Receptors, Transforming Growth Factor beta - genetics | Nitriles - pharmacology | Humans | Activins - metabolism | Recombinant Fusion Proteins - metabolism | Granulosa Cells - drug effects | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Growth Differentiation Factor 9 | Bone Morphogenetic Protein Receptors, Type I | Female | Membrane Proteins - metabolism | Genes, Reporter | Protein-Serine-Threonine Kinases - metabolism | Thymidine - metabolism | Protein Structure, Tertiary | Butadienes - pharmacology | Follicle Stimulating Hormone - metabolism | Granulosa Cells - physiology | Receptors, Growth Factor | Cells, Cultured | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Rats | Activin Receptors, Type I - metabolism | Activin Receptors, Type I - genetics | Bone Morphogenetic Protein Receptors, Type II | Rats, Sprague-Dawley | Bone Morphogenetic Protein 15 | Animals | Receptors, Transforming Growth Factor beta - metabolism | Smad1 Protein | Progesterone - metabolism | Smad Proteins | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Trans-Activators - metabolism | Mitogen-Activated Protein Kinases - metabolism
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3. Full Text Hypergonadotropic Ovarian Failure Associated with an Inherited Mutation of Human Bone Morphogenetic Protein-15 ( BMP15) Gene
by Di Pasquale, Elisa and Beck-Peccoz, Paolo and Persani, Luca
The American Journal of Human Genetics, ISSN 0002-9297, 2004, Volume 75, Issue 1, pp. 106 - 111
Hypergonadotropic ovarian failure is a common cause of female infertility. It is a heterogeneous disorder that, in the most severe forms, is a result of... 
WOMEN | CELLS | INCREASED OVULATION RATE | GENETICS & HEREDITY | INFERTILITY | SHEEP | GROWTH-DIFFERENTIATION FACTOR-9 | OOCYTES | SECRETION | REGION | Amino Acid Sequence | Genetic Predisposition to Disease | Chromosomes, Human, X - genetics | Humans | Intercellular Signaling Peptides and Proteins - genetics | Molecular Sequence Data | Amenorrhea - genetics | Mutation, Missense | Sequence Homology, Amino Acid | Bone Morphogenetic Protein 15 | Growth Differentiation Factor 9 | Pedigree | Karyotyping | Adolescent | Alleles | Ovary - abnormalities | Primary Ovarian Insufficiency - genetics | Adult | Female | Bone Morphogenetic Proteins - genetics | Granulosa Cells - pathology | Human genetics | Research | Report
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4. Full Text Effects of immunization against bone morphogenetic protein-15 and growth differentiation factor-9 on ovarian function in mares
by Davis, Kelli A and Klohonatz, Kristin M and Mora, Darcy S.O and Twenter, Hannah M and Graham, Peter E and Pinedo, Pablo and Eckery, Douglas C and Bruemmer, Jason E
Animal Reproduction Science, ISSN 0378-4320, 05/2018, Volume 192, pp. 69 - 77
Currently there is no contraceptive vaccine that can cause permanent sterility in mares. This study investigates the effect of vaccination against... 
Contraceptive | Equine | Mare | BMP-15 | GDF-9 | INCREASED OVULATION RATE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | HEMORRHAGIC ANOVULATORY FOLLICLES | SHEEP | BMP15 | GDF9 | REPRODUCTIVE BIOLOGY | GENES | MUTATIONS | ESTROUS-CYCLE | Animals | Ovary - immunology | Vaccines, Contraceptive - immunology | Growth Differentiation Factor 9 - immunology | Female | Immunization Schedule | Ovary - physiology | Horses - physiology | Bone Morphogenetic Protein 15 - immunology | Ovulation - immunology | Phosphates | Bone morphogenetic proteins | Contraceptives | Growth | Analysis | Vaccination
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5. Effect of bone morphogenetic protein-15 on gonadotropin-stimulated synthesis of hyaluronan and progesterone in porcine ovarian follicle
by Nagyova, Eva and Nemcova, L and Mlynarcikova, A. Bujnakova and Blaha, M and Prochazka, R and Scsukova, S
Journal of Physiology and Pharmacology, ISSN 0867-5910, 10/2017, Volume 68, Issue 5, pp. 683 - 691
Bone morphogenetic protein-15 (BMP-15), an oocyte-derived growth factor, has been shown to play integral roles in regulation of ovarian follicular function in... 
Granulosa cells | Bone morphogenetic protein-15 | Progesterone | Cumulus extracellular matrix | Hyaluronic acid | Ovarian follicle | MAMMALIAN OVARY | ovarian follicle | PHYSIOLOGY | GRANULOSA-CELLS | PIG OOCYTES | progesterone | cumulus extracellular matrix | granulosa cells | bone morphogenetic protein-15 | hyaluronic acid | IN-VITRO MATURATION | MESSENGER-RNA | EXPANSION | GROWTH-DIFFERENTIATION FACTOR-9 | EXTRACELLULAR-MATRIX | RNA EXPRESSION | OOCYTE-CUMULUS COMPLEXES
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6. Full Text High bone morphogenetic protein-15 level in follicular fluid is associated with high quality oocyte and subsequent embryonic development
by Wu, Yan-Ting and Tang, Li and Cai, Jie and Lu, Xiu-E and Xu, Jian and Zhu, Xiao-Ming and Luo, Qiong and Huang, He-Feng
Human Reproduction, ISSN 0268-1161, 06/2007, Volume 22, Issue 6, pp. 1526 - 1531
BACKGROUND Bone morphogenetic protein-15 (BMP-15) has been shown to influence oocyte maturation and quality. However, no relationship has been established... 
IVF | Embryonic development | Bone morphogenetic protein-15 | Follicular fluid | Oocyte | STIMULATING-HORMONE | INCREASED OVULATION RATE | embryonic development | bone morphogenetic protein-15 | follicular fluid | BMP15 | OBSTETRICS & GYNECOLOGY | IN-VITRO | REPRODUCTIVE BIOLOGY | oocyte | GENE | CYTOPLASMIC MATURATION | GROWTH-DIFFERENTIATION FACTOR-9 | MUTATIONS | KIT-LIGAND | EXPRESSION | Intercellular Signaling Peptides and Proteins - analysis | Estradiol - analysis | Humans | Biomarkers - analysis | Male | Embryonic Development | Follicular Fluid - chemistry | Pregnancy | Sperm Injections, Intracytoplasmic | Bone Morphogenetic Protein 15 | Follicle Stimulating Hormone - analysis | Oocytes - physiology | Embryo, Mammalian - anatomy & histology | Growth Differentiation Factor 9 | Adult | Female | Cleavage Stage, Ovum - cytology
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7. Full Text Bone Morphogenetic Protein-15 Inhibits Follicle-stimulating Hormone (FSH) Action by Suppressing FSH Receptor Expression
by Fumio Otsuka and Shin Yamamoto and Gregory F. Erickson and Shunichi Shimasaki
Journal of Biological Chemistry, ISSN 0021-9258, 04/2001, Volume 276, Issue 14, pp. 11387 - 11392
We have recently reported that oocyte-derived bone morphogenetic protein-15 (BMP-15) can directly modulate follicle-stimulating hormone (FSH) action in rat... 
MAMMALIAN OVARY | CHAIN CLEAVAGE CYTOCHROME-P-450 | MESSENGER-RIBONUCLEIC-ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE OOCYTES | GROWTH-DIFFERENTIATION FACTOR-9 | CUMULUS CELLS | RAT GRANULOSA-CELLS | INDEPENDENT REGULATION | OVULATION RATE | HOMOLOG GDF-9B | Follicle Stimulating Hormone - metabolism | Intercellular Signaling Peptides and Proteins | Cells, Cultured | Rats | Rats, Sprague-Dawley | Receptors, FSH - antagonists & inhibitors | Granulosa Cells - metabolism | Bone Morphogenetic Protein 15 | Animals | Signal Transduction - drug effects | Growth Differentiation Factor 9 | Growth Substances - pharmacology | Female | Growth Substances - metabolism | Receptors, FSH - metabolism
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8. Full Text Effect of intracellular interactions on the processing and secretion of bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9: Implication of the aberrant ovarian phenotype of BMP-15 mutant sheep
by Liao, Wu Xiang and Moore, R. Kelly and Otsuka, Fumio and Shimasaki, Shunichi
Journal of Biological Chemistry, ISSN 0021-9258, 02/2003, Volume 278, Issue 6, pp. 3713 - 3719
Bone morphogenetic protein-15 (BMP-15) and growth and differentiation factor-9 (GDF-9) are members of the transforming growth factor-beta superfamily. Both... 
Cell Line | Electrophoresis, Polyacrylamide Gel | Humans | Intercellular Signaling Peptides and Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Intercellular Signaling Peptides and Proteins - physiology | Bone Morphogenetic Protein 15 | Phenotype | Animals | Growth Differentiation Factor 9 | Female | Sheep | Intercellular Signaling Peptides and Proteins - secretion | Mutation | Ovary - metabolism
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9. Full Text A Covalently Dimerized Recombinant Human Bone Morphogenetic Protein-15 Variant Identifies Bone Morphogenetic Protein Receptor Type 1B as a Key Cell Surface Receptor on Ovarian Granulosa Cells
by Pulkki, Minna M and Mottershead, David G and Pasternack, Arja H and Muggalla, Pranuthi and Ludlow, Helen and van Dinther, Maarten and Myllymaa, Samu and Koli, Katri and ten Dijke, Peter and Laitinen, Mika and Ritvos, Olli
Endocrinology, ISSN 0013-7227, 03/2012, Volume 153, Issue 3, pp. 1509 - 1518
Genetic studies have identified bone morphogenetic protein-15 (BMP15) as an essential regulator of female fertility in humans and in sheep. Oocyte-derived... 
INCREASED OVULATION RATE | SMAD PROTEINS | BMP15 GENE | TRANSFORMING GROWTH-FACTOR-BETA-2 | I RECEPTOR | MUTATION | ENDOCRINOLOGY & METABOLISM | GROWTH-DIFFERENTIATION FACTOR-9 | INHIBIN-B PRODUCTION | FACTOR-BETA SUPERFAMILY | LUTEAL CELLS | Protein Structure, Tertiary | Humans | Gene Expression Regulation | Bone Morphogenetic Protein 15 - metabolism | Cercopithecus aethiops | Recombinant Fusion Proteins - chemistry | Bone Morphogenetic Protein Receptors, Type I - metabolism | Granulosa Cells - metabolism | Homozygote | Animals | Female | Cell Membrane - metabolism | COS Cells | Dimerization | Genes, Reporter | Granulosa Cells - cytology | Ovary - metabolism
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10. Full Text Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary syndrome
by Zhao, Shu-Yun, M.D and Qiao, Jie, M.D and Chen, Yong-Jian, Ph.D and Liu, Ping, Ph.D and Li, Jian, M.Sc and Yan, Jie, M.Sc
Fertility and Sterility, ISSN 0015-0282, 2010, Volume 94, Issue 1, pp. 261 - 267
Objective To evaluate the effect of growth differentiation factor-9 (GDF-9) and bone morphogenetic protein-15 (BMP-15) on the development of follicles among... 
Internal Medicine | Obstetrics and Gynecology | PCOS | follicular development | GDF-9 | BMP-15 | SMAD2 | SHEEP | FAILURE | HAMSTER | BMP15 | OBSTETRICS & GYNECOLOGY | WOMEN | REPRODUCTIVE BIOLOGY | GENES | FOLLICLE-STIMULATING-HORMONE | MUTATIONS | OVULATION RATE | Cumulus Cells - pathology | Polycystic Ovary Syndrome - metabolism | Oocytes - metabolism | Humans | Gene Expression Regulation | Sperm Injections, Intracytoplasmic - methods | Case-Control Studies | Growth Differentiation Factor 9 - biosynthesis | Cumulus Cells - metabolism | Growth Differentiation Factor 9 - antagonists & inhibitors | Bone Morphogenetic Protein 15 - genetics | Adult | Female | Bone Morphogenetic Protein 15 - biosynthesis | Polycystic Ovary Syndrome - pathology | Growth Differentiation Factor 9 - genetics
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11. Expression and biological effects of bone morphogenetic protein-15 in the hen ovary
by Elis, S and Dupont, J and Couty, I and Persani, L and Govoroun, M and Blesbois, E and Batellier, F and Monget, P
Journal of Endocrinology, ISSN 0022-0795, 09/2007, Volume 194, Issue 3, pp. 485 - 497
The bone morphogenetic protein 15 (Bmp15) and growth differentiation factor 9 (Gdf9) genes are two members of the transforming growth factor-beta superfamily.... 
INCREASED OVULATION RATE | SYNERGISTIC ROLES | MESSENGER-RNA | PROGESTERONE SECRETION | FOLLICULAR DEVELOPMENT | CHICKEN GRANULOSA | ENDOCRINOLOGY & METABOLISM | GERMINAL DISC REGION | GROWTH-DIFFERENTIATION FACTOR-9 | BETA SUPERFAMILY | GRANULOSA-CELL PROLIFERATION | Intercellular Signaling Peptides and Proteins - analysis | Ovary - chemistry | Humans | Granulosa Cells - secretion | Molecular Sequence Data | RNA, Messenger - analysis | Phosphoproteins - metabolism | Granulosa Cells - drug effects | Granulosa Cells - metabolism | Chickens - metabolism | Cattle | Growth Differentiation Factor 9 | Base Sequence | Female | Ovary - metabolism | Follicular Phase | Amino Acid Sequence | Progesterone - secretion | Gene Expression | Oocytes - metabolism | Oocytes - chemistry | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Rats | Zebrafish | Reverse Transcriptase Polymerase Chain Reaction | Bone Morphogenetic Protein 15 | Sequence Alignment | Animals | Signal Transduction - drug effects | Cell Differentiation - drug effects | Smad1 Protein - metabolism | Mice
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12. Full Text Oocyte-Specific Overexpression of Mouse Bone Morphogenetic Protein-15 Leads to Accelerated Folliculogenesis and an Early Onset of Acyclicity in Transgenic Mice
by McMahon, Heather E and Hashimoto, Osamu and Mellon, Pamela L and Shimasaki, Shunichi
Endocrinology, ISSN 0013-7227, 06/2008, Volume 149, Issue 6, pp. 2807 - 2815
Whereas mutations in the bmp15 gene cause infertility in ewes and women due to defects in folliculogenesis, most defects in female mice lacking bone... 
INCREASED OVULATION RATE | GRANULOSA-CELLS | BMP15 GENE | ENDOCRINOLOGY & METABOLISM | FOLLICLE-STIMULATING-HORMONE | GROWTH-DIFFERENTIATION FACTOR-9 | SEQUENCE VARIANTS | VAGINAL CYTOLOGY | PREMATURE OVARIAN FAILURE | MUTATIONS | BMP-15 | Ovulation - genetics | Estrus | Humans | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | Bone Morphogenetic Protein 15 | Fertility - genetics | Animals | Oocytes - physiology | Growth Differentiation Factor 9 | Ovarian Follicle - physiology | Polymerase Chain Reaction | Female | Mice | Ovulation - physiology
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13. Full Text Bone morphogenetic protein-15 in follicle fluid combined with age may differentiate between successful and unsuccessful poor ovarian responders
by Wu, Yan-Ting and Wang, Ting-Ting and Chen, Xi-Jing and Zhu, Xiao-Ming and Dong, Min-Yue and Sheng, Jian-Zhong and Xu, Chen-Ming and Huang, He-Feng
Reproductive Biology and Endocrinology, ISSN 1477-7827, 12/2012, Volume 10, Issue 1, pp. 116 - 116
Background: The counselling of poor ovarian responders about the probability of pregnancy remains a puzzle for gynaecologists. The aim of this study was to... 
Retrospective study | Poor response | BMP-15 | IVF-ET | Age | Oocyte | CELLS | QUALITY | BMP15 | REPRODUCTIVE BIOLOGY | HORMONE | RESERVE | ENDOCRINOLOGY & METABOLISM | FSH | IN-VITRO FERTILIZATION | EXPRESSION | Age Factors | Ovarian Follicle - anatomy & histology | Ovulation Induction | Humans | Treatment Outcome | Oocyte Retrieval | Follicular Fluid - chemistry | Pregnancy | Infertility, Female - physiopathology | Sperm Injections, Intracytoplasmic | Fertilization in Vitro | Embryo Transfer | Ovarian Follicle - physiology | Bone Morphogenetic Protein 15 - analysis | Adult | Female | Ovary - drug effects | Infertility, Female - therapy | Ovary - physiopathology | Fertilization in vitro, Human | Bone morphogenetic proteins | Maternal age | Embryo transplantation | Reproductive health | Medicine | Ultrasonic imaging | Womens health | Infertility | Reproductive technologies | Patients | Embryos
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14. Full Text Steady-state level of bone morphogenetic protein-15 in goat ovaries and its influence on in vitro development and survival of preantral follicles
by Celestino, J.J.H and Lima-Verde, I.B and Bruno, J.B and Matos, M.H.T and Chaves, R.N and Saraiva, M.V.A and Silva, J.R.V and Silva, C.M.G and Faustino, L.R and Rossetto, R and Lopes, C.A.P and Donato, M.A.M and Peixoto, C.A and Campello, C.C and Figueiredo, J.R
Molecular and Cellular Endocrinology, ISSN 0303-7207, 2011, Volume 338, Issue 1, pp. 1 - 9
This study investigates steady-state level of bone morphogenetic protein-15 (BMP-15) mRNA in caprine follicles, and the effects of BMP-15 on development of... 
Preantral follicles | Activation | Growth | BMP-15 | Caprine | STIMULATING-HORMONE | PRIMORDIAL FOLLICLES | BONE-MORPHOGENETIC-PROTEIN-15 BMP15 | HOMOLOG GDF-9B | CELL BIOLOGY | BETA SUPERFAMILY MEMBERS | MESSENGER-RNA | FOLLICULAR DEVELOPMENT | ENDOCRINOLOGY & METABOLISM | GROWTH-DIFFERENTIATION FACTOR-9 | GRANULOSA-CELL FUNCTION | GROWTH-DIFFERENTIATION-FACTOR-9 COOPERATE | Cell Survival - drug effects | Microscopy, Electron, Transmission | Oocytes - growth & development | Ovarian Follicle - anatomy & histology | Ovarian Follicle - growth & development | Tissue Culture Techniques | Bone Morphogenetic Protein 15 - metabolism | Goats - growth & development | Ovarian Follicle - drug effects | Animals | Bone Morphogenetic Protein 15 - genetics | Oocytes - drug effects | Female | Transcription, Genetic | Bone Morphogenetic Protein 15 - pharmacology | Ovarian Follicle - metabolism | Bone morphogenetic proteins | Messenger RNA | Universities and colleges
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15. Full Text A Novel Function of Bone Morphogenetic Protein-15 in the Pituitary: Selective Synthesis and Secretion of FSH by Gonadotropes
by Otsuka, Fumio and Shimasaki, Shunichi
Endocrinology, ISSN 0013-7227, 12/2002, Volume 143, Issue 12, pp. 4938 - 4941
Bone morphogenetic protein-15 (BMP-15) has been known to be an oocyte-specific factor and regulate granulosa cell functions. Here, we report that BMP-15 is... 
CELLS | RAT | DISCRETE STAGES | ENDOCRINOLOGY & METABOLISM | FOLLICLE-STIMULATING-HORMONE | FOLLISTATIN | EXPRESSION | BINDING | ACTIVIN | BETA | Transcription, Genetic - drug effects | Receptors, LHRH - genetics | Receptors, FSH - genetics | Ovary - chemistry | RNA, Messenger - analysis | Male | Pituitary Gland - chemistry | Pituitary Gland, Anterior - metabolism | Intercellular Signaling Peptides and Proteins - physiology | Growth Differentiation Factor 9 | Female | Bone Morphogenetic Proteins - pharmacology | Luteinizing Hormone - biosynthesis | Transforming Growth Factor beta | Luteinizing Hormone - secretion | Bone Morphogenetic Protein 6 | Cell Line | Gene Expression | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Rats | Follicle Stimulating Hormone - biosynthesis | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | Bone Morphogenetic Protein 15 | Inhibin-beta Subunits - pharmacology | Animals | Follicle Stimulating Hormone - secretion | Activins - pharmacology | Intercellular Signaling Peptides and Proteins - pharmacology | Luteinizing Hormone, beta Subunit - genetics | Follicle Stimulating Hormone, beta Subunit - genetics | Mice | Bone Morphogenetic Protein 7 | Pituitary Gland - physiology
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16. Full Text Potential role of bone morphogenetic protein-15 in zebrafish follicle development and oocyte maturation
by Peng, Chun and Clelland, Eric and Tan, Qian
Comparative Biochemistry and Physiology, Part A, ISSN 1095-6433, 2009, Volume 153, Issue 1, pp. 83 - 87
Bone morphogenetic protein (BMP)-15 is a member of the transforming growth factor β (TGF-β) superfamily and is closely related to growth and differentiation... 
Ovary | Zebrafish | BMP-15 | Oocyte maturation | INCREASED OVULATION RATE | PHYSIOLOGY | TGF-BETA | BMP15 GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH-DIFFERENTIATION-FACTOR-9 GDF9 | BONE-MORPHOGENETIC-PROTEIN-15 BMP15 | PREMATURE OVARIAN FAILURE | SPATIOTEMPORAL EXPRESSION | ZOOLOGY | MESSENGER-RNA | GROWTH-DIFFERENTIATION FACTOR-9 | MEMBRANE PROGESTIN RECEPTOR | Oogenesis | Animals | Bone Morphogenetic Protein 15 - chemistry | Oocytes - growth & development | Ovarian Follicle - growth & development | Zebrafish - metabolism | Bone Morphogenetic Protein 15 - metabolism | Female | Ovarian Follicle - metabolism | Zebrafish - growth & development
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17. Full Text The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: Characterization of the purified untagged processed mature region
by Pulkki, Minna M and Myllymaa, Samu and Pasternack, Arja and Lun, Stanley and Ludlow, Helen and Al-Qahtani, Ahmed and Korchynskyi, Olexandr and Groome, Nigel and Juengel, Jennifer L and Kalkkinen, Nisse and Laitinen, Mika and Ritvos, Olli and Mottershead, David G
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2011, Volume 332, Issue 1-2, pp. 106 - 115
Oocyte-derived bone morphogenetic protein-15 (BMP15) is critical for the regulation of mammalian fertility. Previously we have found that a C-terminal His -tag... 
Human | Granulosa cell | Bone morphogenetic protein | BMP15 | GRANULOSA-LUTEAL CELLS | PREMATURE OVARIAN FAILURE | INDIAN WOMEN | CELL BIOLOGY | MESSENGER-RNA | TRANSFORMING GROWTH-FACTOR-BETA-2 | ENDOCRINOLOGY & METABOLISM | GROWTH-DIFFERENTIATION FACTOR-9 | INHIBIN-B PRODUCTION | FACTOR-BETA SUPERFAMILY | OVULATION RATE | GROWTH-DIFFERENTIATION-FACTOR-9 COOPERATE | Luteal Cells - metabolism | Bone Morphogenetic Protein 15 - chemistry | Humans | Bone Morphogenetic Protein 15 - metabolism | Rats | Luteal Cells - cytology | Animals | Oocytes - physiology | Growth Differentiation Factor 9 - metabolism | Growth Differentiation Factor 9 - chemistry | Bone Morphogenetic Protein 15 - genetics | HEK293 Cells | Female | Growth Differentiation Factor 9 - genetics | Transforming Growth Factor beta - metabolism | Genes, Reporter | Stimulators | Control | Fertility | Rodents | Bones | Biochemistry | Flags | Recombinant
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