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03/2008
The incidence of 5-fluorouracil (5-FU)-related cardiotoxicity seems to be dosage and schedule dependent. Although various other cardiac events have been... 
5-fluorouracil | Bradycardia
Web Resource
The New England Journal of Medicine, ISSN 0028-4793, 11/2009, Volume 361, Issue 22, pp. 2123 - 2134
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2013, Volume 123, Issue 4, pp. 1798 - 1808
Journal Article
Circulation Research, ISSN 0009-7330, 10/2017, Volume 121, Issue 9, pp. 1058 - 1068
RATIONALE:Downregulation of the pacemaking ion channel, HCN4 (hyperpolarization-activated cyclic nucleotide gated channel 4), and the corresponding ionic... 
sinoatrial node | ion channel remodeling | athletes | micro-RNAs | sinus bradycardia | exercise training | CARDIAC & CARDIOVASCULAR SYSTEMS | INTRONIC MICRORNAS | HEART-FAILURE | DOWN-REGULATION | O-GLCNAC TRANSFERASE | HIGH VAGAL TONE | ATRIAL-FIBRILLATION | HOST GENES | ENDURANCE EXERCISE | PERIPHERAL VASCULAR DISEASE | CARDIOMYOCYTE DIFFERENTIATION | HEMATOLOGY | Gene Targeting - methods | Bradycardia - genetics | Humans | Physical Conditioning, Animal - methods | Male | MicroRNAs - metabolism | Gene Knockdown Techniques - methods | Potassium Channels - metabolism | Young Adult | Bradycardia - metabolism | Muscle Proteins - metabolism | Adult | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism | Mice, Inbred C57BL | Sinoatrial Node - physiopathology | Bradycardia - physiopathology | Physical Conditioning, Animal - physiology | Potassium Channels - genetics | Muscle Proteins - genetics | Animals | Adolescent | Sinoatrial Node - metabolism | Exercise - physiology | Mice | MicroRNAs - genetics | Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - genetics | Bradycardia | Exercise | Physiological aspects | Ion channels | Research | Nucleotide sequencing | Athletes | Health aspects | Risk factors | DNA sequencing | Cardiac arrhythmia | Animal models | Physical training | MiRNA | Reverse transcription | Polymerase chain reaction | Heart rate | Sinuses | Sinus | Computer applications | Fitness training programs | Nkx2.5 protein | Hyperpolarization | Ion channels (cyclic nucleotide-gated) | Index Medicus | 10063 | 10032 | 10035 | Molecular Medicine | 10001 | 10003
Journal Article
Journal Article
Nature, ISSN 0028-0836, 02/2003, Volume 421, Issue 6923, pp. 634 - 639
Journal Article
Ultrasound in Obstetrics & Gynecology, ISSN 0960-7692, 09/2017, Volume 50, Issue S1, pp. 367 - 367
Journal Article
Journal Article
2009, Volume 1, 1
Reference
Journal of Applied Physiology, ISSN 8750-7587, 06/2015, Volume 118, Issue 11, pp. 1344 - 1355
Journal Article