X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (10246) 10246
Book Review (1921) 1921
Publication (1256) 1256
Book Chapter (71) 71
Conference Proceeding (50) 50
Dissertation (27) 27
Archival Material (1) 1
Government Document (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (7221) 7221
humans (6587) 6587
braf (5193) 5193
oncology (3983) 3983
mutation (3889) 3889
cancer (3268) 3268
female (3200) 3200
proto-oncogene proteins b-raf - genetics (3033) 3033
melanoma (3014) 3014
male (2988) 2988
middle aged (2516) 2516
aged (2063) 2063
braf mutation (2058) 2058
adult (2029) 2029
tumors (1686) 1686
pathology (1625) 1625
genetic aspects (1503) 1503
braf mutations (1445) 1445
prognosis (1346) 1346
colorectal cancer (1290) 1290
metastasis (1230) 1230
gene mutations (1215) 1215
melanoma - genetics (1202) 1202
mutations (1184) 1184
carcinoma (1114) 1114
vemurafenib (1089) 1089
metastatic melanoma (1074) 1074
kras (1054) 1054
analysis (1044) 1044
research (1042) 1042
animals (1040) 1040
cell biology (1032) 1032
aged, 80 and over (1020) 1020
survival (996) 996
melanoma - pathology (986) 986
expression (973) 973
thyroid neoplasms - genetics (961) 961
neoplasms (944) 944
care and treatment (932) 932
immunohistochemistry (928) 928
microsatellite instability (918) 918
melanoma - drug therapy (914) 914
colorectal neoplasms - genetics (909) 909
thyroid cancer (908) 908
cell line, tumor (906) 906
article (846) 846
thyroid neoplasms - pathology (822) 822
dna mutational analysis (801) 801
dermatology (767) 767
proto-oncogene proteins b-raf - metabolism (735) 735
diagnosis (724) 724
kinases (721) 721
chemotherapy (715) 715
surgery (695) 695
activation (686) 686
braf v600e mutation (678) 678
proto-oncogene proteins b-raf - antagonists & inhibitors (670) 670
antineoplastic agents - therapeutic use (663) 663
colorectal neoplasms - pathology (662) 662
young adult (659) 659
health aspects (657) 657
endocrinology & metabolism (655) 655
gene (651) 651
biomarkers, tumor - genetics (639) 639
medicine & public health (629) 629
skin neoplasms - pathology (622) 622
skin neoplasms - genetics (618) 618
ras proteins - genetics (602) 602
pathway (596) 596
resistance (588) 588
digestive system diseases (586) 586
b-raf (585) 585
mutation - genetics (582) 582
therapy (580) 580
adolescent (578) 578
mice (570) 570
malignant-melanoma (567) 567
open-label (563) 563
colon-cancer (557) 557
retrospective studies (557) 557
biochemistry & molecular biology (542) 542
signal transduction (540) 540
abridged index medicus (530) 530
development and progression (527) 527
gene expression (524) 524
patients (519) 519
proteins (519) 519
neoplasm staging (511) 511
dna methylation (506) 506
treatment outcome (503) 503
genes (499) 499
proto-oncogene proteins - genetics (498) 498
medicine, research & experimental (492) 492
acquired-resistance (490) 490
targeted therapy (487) 487
immunotherapy (486) 486
papillary thyroid carcinoma (483) 483
inhibition (471) 471
phenotype (471) 471
melanoma - metabolism (465) 465
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (10028) 10028
French (95) 95
German (95) 95
Spanish (34) 34
Korean (27) 27
Russian (22) 22
Chinese (10) 10
Polish (10) 10
Japanese (8) 8
Czech (5) 5
Portuguese (5) 5
Hungarian (4) 4
Italian (2) 2
Turkish (2) 2
Croatian (1) 1
Persian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Gynecologic Oncology, ISSN 0090-8258, 2014, Volume 134, Issue 1, pp. 10 - 14
Journal Article
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 1/2016, Volume 142, Issue 1, pp. 89 - 100
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 7/2011, Volume 122, Issue 1, pp. 11 - 19
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 09/2014, Volume 38, Issue 9, pp. 1235 - 1241
Journal Article
Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7315, pp. 596 - 599
B-RAF is the most frequently mutated protein kinase in human cancers. The finding that oncogenic mutations in BRAF are common in melanoma, followed by the... 
ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | MUTATION | KERATOACANTHOMAS | SENSITIVITY | SENESCENCE | SORAFENIB | HUMAN CANCER | PROGRESSION | BRAF(V600E) | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Macaca fascicularis | Melanoma - enzymology | Substrate Specificity | Positron-Emission Tomography | Extracellular Signal-Regulated MAP Kinases - metabolism | Indoles - administration & dosage | Neoplasm Metastasis | Melanoma - genetics | Phosphorylation - drug effects | Mutant Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Sulfonamides - chemistry | Mutant Proteins - genetics | Models, Molecular | Rats | Mutant Proteins - metabolism | Melanoma - pathology | Mutation - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Indoles - adverse effects | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Mutant Proteins - chemistry | Alleles | Dogs | Sulfonamides - adverse effects | Indoles - therapeutic use | Indoles - chemistry | Sulfonamides - administration & dosage | Control | Gene mutations | Melanoma | Development and progression | Genetic aspects | Research | Health aspects | Protein kinases | Cancer | Proteins | Mutation | Kinases | Rodents | Index Medicus | targeted therapy | melanoma | BRAF | PLX4032 | biomarker | oncogene
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 4, pp. 435 - 445
Journal Article
CLINICAL ENDOCRINOLOGY, ISSN 0300-0664, 06/2014, Volume 80, Issue 6, pp. 899 - 904
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2012, Volume 367, Issue 17, pp. 1596 - 1606
In this study, mortality from colorectal cancer was reduced by about 80% in a subgroup of patients with tumors that expressed a mutated, activated form of... 
ISLAND METHYLATOR PHENOTYPE | COLON-CANCER | MEDICINE, GENERAL & INTERNAL | METASTASIS | INHIBITION | RANDOMIZED-TRIALS | BRAF MUTATION | MICROSATELLITE INSTABILITY | RISK | PERSONALIZED MEDICINE | MOLECULAR PATHOLOGICAL EPIDEMIOLOGY | Colorectal Neoplasms - mortality | Cyclooxygenase 2 Inhibitors - pharmacology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Proportional Hazards Models | Male | Phosphatidylinositol 3-Kinases - genetics | Class I Phosphatidylinositol 3-Kinases | Signal Transduction - drug effects | Colorectal Neoplasms - drug therapy | Cyclooxygenase 2 Inhibitors - therapeutic use | Survival Analysis | Female | Aged | Aspirin - therapeutic use | Biomarkers, Tumor - genetics | Aspirin - pharmacology | Mutation | Drugs | Dose-response relationship (Biochemistry) | Aspirin | Gene mutations | Analysis | Colorectal cancer | Dosage and administration | Genetic aspects | Product/Service Evaluations | Research | Drug therapy | Oncogenes | Phenotypes | Tumor markers | Colorectal carcinoma | AKT protein | Microsatellite instability | Long interspersed nucleotide elements | Survival | Epidemiology | 1-Phosphatidylinositol 3-kinase | Prostaglandin endoperoxide synthase | Colon cancer | Rectum | DNA methylation | Death | Cyclooxygenase-2 | Diagnosis | Colon | Methylation | CpG islands | Apoptosis | Index Medicus | Abridged Index Medicus
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2011, Volume 121, Issue 3, pp. 397 - 405
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine sarcoma viral oncogene homolog B1... 
Brain tumor | Pathology | Neurosciences | Ganglioglioma | V600E mutation | Medicine & Public Health | BRAF | Pleomorphic xanthoastrocytoma | GLIOMAS | B-RAF GENE | PATHOLOGY | CANCER | NEUROSCIENCES | CLINICAL NEUROLOGY | PATHWAY ACTIVATION | ATYPICAL TERATOID/RHABDOID TUMOR | COMPONENT | DUPLICATION | INHIBITOR | MAPK PATHWAY | EXPRESSION | Astrocytoma - genetics | Gene Frequency - genetics | World Health Organization | Signal Transduction | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Exons - genetics | Mutation, Missense - genetics | Young Adult | Ganglioglioma - genetics | Astrocytoma - pathology | Proto-Oncogene Proteins B-raf - genetics | Ganglioglioma - pathology | Adolescent | Adult | Nervous System Neoplasms - genetics | Retrospective Studies | Child | Nervous System Neoplasms - pathology | Medical colleges | Molecular genetics | Sarcoma | Neurons | Brain tumors | Oncology, Experimental | Melanoma | Thyroid diseases | Research | Codon | Gene mutations | Gliomas | Analysis | Genetic research | Genetic aspects | Cancer | Index Medicus | meningioma | Pediatrics | Exons | Glioblastoma | Clinical trials | Insertion | Adenoma | Neuronal-glial interactions | Missense mutation | Sheaths | Colon | Astrocytoma | Oncogenes | Peripheral nervous system | Astrocytes | Base pairs | Central nervous system diseases | Glioma | Pituitary | Codons | papillary thyroid carcinoma | Tumors
Journal Article