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Journal of cancer research and clinical oncology, ISSN 0171-5216, 1/2016, Volume 142, Issue 1, pp. 89 - 100
BRAF V600E | Medicine & Public Health | Hematology | Glioma | IDH1 | Classification | KIAA1549 – BRAF | Oncology | Cancer Research | Internal Medicine | KIAA1549–BRAF | Life Sciences & Biomedicine | Science & Technology | Oncogene Proteins, Fusion - metabolism | Prognosis | Follow-Up Studies | Tissue Array Analysis | Humans | Middle Aged | Child, Preschool | Infant | Male | Immunoenzyme Techniques | Young Adult | Polymerase Chain Reaction | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Child | Infant, Newborn | Proto-Oncogene Proteins B-raf - metabolism | Central Nervous System Neoplasms - classification | Central Nervous System Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Mutation - genetics | Central Nervous System Neoplasms - pathology | Oncogene Proteins, Fusion - genetics | Proto-Oncogene Proteins B-raf - genetics | Adolescent | Isocitrate Dehydrogenase - metabolism | Aged | Biomarkers, Tumor - genetics | Neoplasm Staging | Immunohistochemistry | Pediatrics | Genetic aspects | Gene mutations | Gliomas | Analysis | Index Medicus
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Annals of oncology, ISSN 0923-7534, 07/2017, Volume 28, Issue 7, pp. 1631 - 1639
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Cancer, ISSN 0008-543X, 08/2013, Volume 119, Issue 15, pp. 2765 - 2770
microsatellite instability | immunohistochemistry | BRAFV600E mutation | BRAFV600E protein | colon cancer | mutation | BRAF | protein | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Colonic Neoplasms - genetics | Microsatellite Instability | Prognosis | Prospective Studies | Antibodies - chemistry | Humans | Middle Aged | Male | Immunohistochemistry - methods | Point Mutation | Proto-Oncogene Proteins B-raf - biosynthesis | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Antibodies - genetics | Female | Aged | Biomarkers, Tumor - genetics | Colonic Neoplasms - enzymology | Neoplasm Staging | Biomarkers, Tumor - biosynthesis | Care and treatment | Colon cancer | Gene mutations | Patient outcomes | Physiological aspects | Genetic aspects | Research | Diagnosis | Gene expression | Index Medicus | Abridged Index Medicus | MSI
Journal Article
Clinical endocrinology (Oxford), ISSN 0300-0664, 11/2017, Volume 87, Issue 5, pp. 411 - 417
BRAF V600E | meta‐analysis | papillary thyroid carcinoma | review | BRAF mutation | TERT promoter | meta-analysis | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Risk Assessment - methods | Thyroid Neoplasms - diagnosis | Thyroid Neoplasms - genetics | Carcinoma, Papillary - genetics | Prognosis | Telomerase - genetics | Proto-Oncogene Proteins B-raf - genetics | Humans | Mutation | Promoter Regions, Genetic - genetics | Carcinoma, Papillary - diagnosis | Thyroid Cancer, Papillary | Medical research | Carcinoma | Gene mutations | Analysis | Thyroid diseases | Medicine, Experimental | Genetic aspects | Cancer | Thyroid cancer | Risk groups | Papillary thyroid carcinoma | Genotypes | Tumors | Thyroid | Index Medicus
Journal Article
Acta neuropathologica, ISSN 0001-6322, 7/2011, Volume 122, Issue 1, pp. 11 - 19
V600E | Immunohistochemistry | Pathology | Neurosciences | Biomarker | Medicine & Public Health | Melanoma | BRAF | Mutation | Monoclonal antibody | Papillary thyroid carcinoma | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Predictive Value of Tests | Thyroid Neoplasms - diagnosis | Melanoma - diagnosis | Prognosis | Humans | Brain Neoplasms - metabolism | Carcinoma, Papillary - metabolism | Brain Neoplasms - secondary | Biomarkers, Tumor - metabolism | Female | Proto-Oncogene Proteins B-raf - metabolism | Melanoma - metabolism | Brain Neoplasms - diagnosis | Mice, Inbred C57BL | Mutation - genetics | Carcinoma, Papillary - pathology | Melanoma - secondary | Immunohistochemistry - methods | Antibodies, Monoclonal - genetics | Animals | Proto-Oncogene Proteins B-raf - genetics | Biomarkers, Tumor - genetics | Mice | Carcinoma, Papillary - diagnosis | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Medical colleges | Sarcoma | Oncology, Experimental | Thyroid diseases | Amino acids | Metastasis | Research | Gene mutations | Analysis | Monoclonal antibodies | Genetic aspects | Cancer | Index Medicus
Journal Article
The American journal of surgical pathology, ISSN 0147-5185, 09/2014, Volume 38, Issue 9, pp. 1235 - 1241
BRAF V600 allele-specific PCR | BRAF V600E | BRAF V600 qPCR | the Cobas 4800 BRAF V600 mutation test | colon cancer | immunohistochemistry | Sanger sequencing | Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Immunohistochemistry | Predictive Value of Tests | ras Proteins - genetics | Colonic Neoplasms - genetics | Proto-Oncogene Proteins p21(ras) | United States | Humans | Middle Aged | Male | DNA Mutational Analysis | DNA Mismatch Repair | Polymerase Chain Reaction | Poland | Adult | Female | Adenocarcinoma - genetics | Genetic Predisposition to Disease | Reproducibility of Results | Membrane Proteins - genetics | Adenocarcinoma - enzymology | Proto-Oncogene Proteins - genetics | Adenocarcinoma - secondary | Automation, Laboratory | Phenotype | Biopsy | GTP Phosphohydrolases - genetics | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Aged | Biomarkers, Tumor - genetics | Colonic Neoplasms - enzymology | Mutation | Index Medicus | the cobas® 4800 BRAF V600 Mutation Test
Journal Article
Gynecologic oncology, ISSN 0090-8258, 2014, Volume 134, Issue 1, pp. 10 - 14
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | MAPK pathway | Vaginal melanoma | NRAS | BRAF | Urogenital tract melanoma | KIT | Oncology | Life Sciences & Biomedicine | Obstetrics & Gynecology | Science & Technology | Melanoma - epidemiology | Exons | Humans | Middle Aged | Netherlands - epidemiology | Melanoma - enzymology | Genital Neoplasms, Female - epidemiology | Formaldehyde | MAP Kinase Signaling System | Paraffin Embedding | Melanoma - genetics | Aged, 80 and over | Adult | Female | Proto-Oncogene Proteins c-kit - genetics | Genital Neoplasms, Female - enzymology | Retrospective Studies | Tissue Fixation | Genital Neoplasms, Female - genetics | Membrane Proteins - genetics | Ureteral Neoplasms - genetics | Molecular Epidemiology | GTP Phosphohydrolases - genetics | Proto-Oncogene Proteins B-raf - genetics | Aged | Mutation | Genetic aspects | Melanoma | Index Medicus
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Full Text
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF -mutant melanoma
Nature (London), ISSN 0028-0836, 09/2010, Volume 467, Issue 7315, pp. 596 - 599
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Macaca fascicularis | Melanoma - enzymology | Substrate Specificity | Positron-Emission Tomography | Extracellular Signal-Regulated MAP Kinases - metabolism | Indoles - administration & dosage | Neoplasm Metastasis | Melanoma - genetics | Phosphorylation - drug effects | Mutant Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Sulfonamides - chemistry | Mutant Proteins - genetics | Models, Molecular | Rats | Mutant Proteins - metabolism | Melanoma - pathology | Mutation - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Indoles - adverse effects | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Mutant Proteins - chemistry | Alleles | Dogs | Sulfonamides - adverse effects | Indoles - therapeutic use | Indoles - chemistry | Sulfonamides - administration & dosage | Control | Gene mutations | Melanoma | Development and progression | Genetic aspects | Research | Health aspects | Protein kinases | Cancer | Proteins | Mutation | Kinases | Rodents | Index Medicus | targeted therapy | melanoma | BRAF | PLX4032 | biomarker | oncogene
Journal Article
Genes & development, ISSN 0890-9369, 06/2012, Volume 26, Issue 11, pp. 1131 - 1155
MITF pathway | BRAF | Melanoma | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Melanoma - diagnosis | Animals | Microphthalmia-Associated Transcription Factor - metabolism | Cell Cycle | Signal Transduction | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Humans | Melanoma - drug therapy | Melanoma - pathology | Microphthalmia-Associated Transcription Factor - genetics | Proto-Oncogene Proteins B-raf - metabolism | Care and treatment | Cancer patients | Usage | Gene mutations | Medical care | Research | Genetic transcription | Health aspects | Cancer | Index Medicus | melanoma | Review
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