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JAMA, ISSN 0098-7484, 04/2013, Volume 309, Issue 14, pp. 1493 - 1501
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 7/2011, Volume 122, Issue 1, pp. 11 - 19
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2017, Volume 23, Issue 1, pp. 104 - 115
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 09/2014, Volume 38, Issue 9, pp. 1235 - 1241
Journal Article
Journal Article
THYROID, ISSN 1050-7256, 10/2013, Volume 23, Issue 10, pp. 1277 - 1283
Background: Clinical benefit from cytotoxic chemotherapy for metastatic papillary thyroid carcinoma (PTC) is disappointing, and effective therapeutic... 
CELLS | PHASE-II TRIAL | MELANOMA | SIGNALING PATHWAY GENES | GROWTH | ENDOCRINOLOGY & METABOLISM | BRAF V600E MUTATION | KINASE INHIBITORS | EXPERIENCE | SORAFENIB | CARCINOMA | Lung Neoplasms - drug therapy | Carcinoma, Papillary - genetics | Follow-Up Studies | Humans | Middle Aged | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Male | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Carcinoma, Papillary - secondary | Indoles - administration & dosage | Dose-Response Relationship, Drug | Lung Neoplasms - secondary | Antineoplastic Agents - adverse effects | Female | Carcinoma - pathology | Proto-Oncogene Proteins B-raf - metabolism | Carcinoma - drug therapy | Lung Neoplasms - genetics | Molecular Targeted Therapy - adverse effects | Carcinoma, Papillary - drug therapy | Cancer Care Facilities | Carcinoma, Papillary - pathology | Thyroid Cancer, Papillary | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Thyroid Neoplasms - genetics | Vemurafenib | Indoles - adverse effects | Sulfonamides - therapeutic use | Thyroid Neoplasms - drug therapy | Tumor Burden - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Survival Analysis | Sulfonamides - adverse effects | Carcinoma - genetics | Indoles - therapeutic use | Carcinoma - metabolism | Mutation | Sulfonamides - administration & dosage | Amino Acid Substitution | Cohort Studies | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology
Journal Article
Lancet Oncology, ISSN 1470-2045, 07/2016, Volume 17, Issue 7, pp. 984 - 993
Journal Article
BLOOD, ISSN 0006-4971, 08/2014, Volume 124, Issue 7, pp. 1119 - 1126
Histiocytoses are a group of heterogeneous diseases that mostly comprise Langerhans cell histiocytosis (LCH) and non-LCH. The association of LCH with non-LCH... 
CARDIAC INVOLVEMENT | INTERFERON-ALPHA | EOSINOPHILIC GRANULOMA | PULMONARY INVOLVEMENT | DENDRITIC CELLS | BRAF MUTATIONS | FOLLOW-UP | PATIENT | SKIN | OF-THE-LITERATURE | HEMATOLOGY
Journal Article
Lancet Oncology, ISSN 1470-2045, 10/2017, Volume 18, Issue 10, pp. 1307 - 1316
Background: BRAF(V600E) mutation occurs in 1-2% of lung adenocarcinomas and acts as an oncogenic driver. Dabrafenib, alone or combined with trametinib, has... 
SURVIVAL | HARBORING BRAF MUTATIONS | 1ST-LINE TREATMENT | MULTICENTER | MELANOMA | PEMBROLIZUMAB | ONCOLOGY | CRIZOTINIB | MULTICOHORT | CHEMOTHERAPY | EGFR
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2011, Volume 121, Issue 3, pp. 397 - 405
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine sarcoma viral oncogene homolog B1... 
Brain tumor | Pathology | Neurosciences | Ganglioglioma | V600E mutation | Medicine & Public Health | BRAF | Pleomorphic xanthoastrocytoma | GLIOMAS | B-RAF GENE | PATHOLOGY | CANCER | NEUROSCIENCES | CLINICAL NEUROLOGY | PATHWAY ACTIVATION | ATYPICAL TERATOID/RHABDOID TUMOR | COMPONENT | DUPLICATION | INHIBITOR | MAPK PATHWAY | EXPRESSION | Astrocytoma - genetics | Gene Frequency - genetics | World Health Organization | Signal Transduction | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Exons - genetics | Mutation, Missense - genetics | Young Adult | Ganglioglioma - genetics | Astrocytoma - pathology | Proto-Oncogene Proteins B-raf - genetics | Ganglioglioma - pathology | Adolescent | Adult | Nervous System Neoplasms - genetics | Retrospective Studies | Child | Nervous System Neoplasms - pathology | Medical colleges | Molecular genetics | Sarcoma | Neurons | Brain tumors | Oncology, Experimental | Melanoma | Thyroid diseases | Research | Codon | Gene mutations | Gliomas | Analysis | Genetic research | Genetic aspects | Cancer | meningioma | Pediatrics | Exons | Glioblastoma | Clinical trials | Insertion | Adenoma | Neuronal-glial interactions | Missense mutation | Sheaths | Colon | Astrocytoma | Oncogenes | Peripheral nervous system | Astrocytes | Base pairs | Central nervous system diseases | Glioma | Pituitary | Codons | papillary thyroid carcinoma | Tumors
Journal Article
by Kim, TH and Park, YJ and Lim, JA and Ahn, HY and Lee, EK and Lee, YJ and Kim, KW and Hahn, SK and Youn, YK and Kim, KH and Cho, BY and Park, DJ
CANCER, ISSN 0008-543X, 04/2012, Volume 118, Issue 7, pp. 1764 - 1773
BACKGROUND: The effects of the BRAF(V600E) mutation on prognostic factors and poor clinical outcomes in papillary thyroid cancer (PTC) have not been fully... 
POPULATION | METAANALYSIS | meta-analysis | BRAF V600E MUTATION | BRAF | thyroid cancer | V600E | papillary | ONCOLOGY | HIGH-RISK | GROWTH-FACTOR | papillary thyroid carcinoma | HIGH PREVALENCE | CARCINOMA | PROGRESSION | CLINICOPATHOLOGICAL FEATURES | GENETIC ALTERATIONS
Journal Article