2002, International review of neurobiology, ISBN 0123668522, Volume 51., xiv, 555 p., [10] p. of plates
Regulation of glucose at the biochemical level affects every area of the brain, and has impact from cellular to behavioral brain function. It plays an...
Brain | Pathophysiology | Depression, Mental | Physiology | Glucose | Diabetes | Metabolism
Brain | Pathophysiology | Depression, Mental | Physiology | Glucose | Diabetes | Metabolism
Book
Journal of Comparative Physiology B, ISSN 0174-1578, 12/2012, Volume 182, Issue 8, pp. 1015 - 1045
Teleost fishes represent a highly diverse group consisting of more than 20,000 species living across all aquatic environments. This group has significant...
Biochemistry, general | Brain | Human Physiology | Zoology | Liver | Dietary carbohydrate | Biomedicine general | Life Sciences | Animal Physiology | Glucose metabolism | Fish | Muscle | Glucosensing | BASS DICENTRARCHUS-LABRAX | PHYSIOLOGY | JUVENILE RAINBOW-TROUT | HIGH-CARBOHYDRATE-DIET | BREAM SPARUS-AURATA | ZOOLOGY | GLUCAGON-LIKE PEPTIDE-1 | INSULIN-INDUCED HYPOGLYCEMIA | SALMON SALMO-SALAR | EEL ANGUILLA-ROSTRATA | TROUT ONCORHYNCHUS-MYKISS | GROWTH-FACTOR-I | Brain - metabolism | Dietary Carbohydrates - administration & dosage | Animals | Digestive System - metabolism | Glucose - metabolism | Homeostasis | Dietary Carbohydrates - metabolism | Fishes - physiology | Animal behavior | Analysis | Fishes | Physiological aspects | Carbohydrate metabolism | Glucose | Dextrose
Biochemistry, general | Brain | Human Physiology | Zoology | Liver | Dietary carbohydrate | Biomedicine general | Life Sciences | Animal Physiology | Glucose metabolism | Fish | Muscle | Glucosensing | BASS DICENTRARCHUS-LABRAX | PHYSIOLOGY | JUVENILE RAINBOW-TROUT | HIGH-CARBOHYDRATE-DIET | BREAM SPARUS-AURATA | ZOOLOGY | GLUCAGON-LIKE PEPTIDE-1 | INSULIN-INDUCED HYPOGLYCEMIA | SALMON SALMO-SALAR | EEL ANGUILLA-ROSTRATA | TROUT ONCORHYNCHUS-MYKISS | GROWTH-FACTOR-I | Brain - metabolism | Dietary Carbohydrates - administration & dosage | Animals | Digestive System - metabolism | Glucose - metabolism | Homeostasis | Dietary Carbohydrates - metabolism | Fishes - physiology | Animal behavior | Analysis | Fishes | Physiological aspects | Carbohydrate metabolism | Glucose | Dextrose
Journal Article
Current Opinion in Neurobiology, ISSN 0959-4388, 2017, Volume 45, pp. 156 - 161
Highlights • Neuronal activity upregulates glycolysis at nerve terminals. • Glycolysis is essential for synaptic function. • The availability of the cofactor...
Neurology | Psychiatry | ENERGY | SYNAPTIC FUNCTION | STIMULATION | AXON DEGENERATION | GLYCOLYTIC-ENZYMES | NEURONS | GLUT4 | KETOGENIC DIET | NEUROSCIENCES | BRAIN | SHUTTLE | Glycolysis - physiology | Animals | Synapses - metabolism | Synaptic Transmission - physiology | Energy Metabolism | Humans | Glucose - metabolism | Physiological aspects | Glucose metabolism | Glucose | Dextrose
Neurology | Psychiatry | ENERGY | SYNAPTIC FUNCTION | STIMULATION | AXON DEGENERATION | GLYCOLYTIC-ENZYMES | NEURONS | GLUT4 | KETOGENIC DIET | NEUROSCIENCES | BRAIN | SHUTTLE | Glycolysis - physiology | Animals | Synapses - metabolism | Synaptic Transmission - physiology | Energy Metabolism | Humans | Glucose - metabolism | Physiological aspects | Glucose metabolism | Glucose | Dextrose
Journal Article
Progress in Neurobiology, ISSN 0301-0082, 09/2013, Volume 108, pp. 21 - 43
Alzheimer's disease (AD) is an age-related devastating neurodegenerative disorder, which severely impacts on the global economic development and healthcare...
Oxidative stress | Mitochondrial dysfunction | Glycogen synthase kinase 3 | Tau | Autophagy | Advanced glycation endproducts | Glucagon-like peptide-1 | Excitotoxicity | Insulin resistance | Peroxisome proliferator-activated receptors | Alzheimer's disease | Positron emission tomography | Thiamine | Cerebral hypometabolism | Apoptosis | KETOGLUTARATE DEHYDROGENASE COMPLEX | THIAMINE-DEPENDENT ENZYMES | INSULIN IMPROVES COGNITION | INTESTINAL ALKALINE-PHOSPHATASE | CENTRAL-NERVOUS-SYSTEM | GLYCATION END-PRODUCTS | AMYLOID PRECURSOR PROTEIN | MILD COGNITIVE IMPAIRMENT | CHARACTERISTIC TRANSKETOLASE ALTERATIONS | NEUROSCIENCES | A beta | POSITRON-EMISSION-TOMOGRAPHY | Glucose Transport Proteins, Facilitative - metabolism | Thiamine - metabolism | Humans | Oxidative Stress - physiology | Alzheimer Disease - metabolism | Alzheimer Disease - therapy | Biomarkers | Glucose - metabolism | Alzheimer Disease - chemically induced | Diabetes Mellitus, Type 2 - complications | Brain Chemistry - physiology | Glucose metabolism | Amyloid beta-protein | Physiological aspects | Glucose | Diagnosis | Health aspects | Dextrose | Age
Oxidative stress | Mitochondrial dysfunction | Glycogen synthase kinase 3 | Tau | Autophagy | Advanced glycation endproducts | Glucagon-like peptide-1 | Excitotoxicity | Insulin resistance | Peroxisome proliferator-activated receptors | Alzheimer's disease | Positron emission tomography | Thiamine | Cerebral hypometabolism | Apoptosis | KETOGLUTARATE DEHYDROGENASE COMPLEX | THIAMINE-DEPENDENT ENZYMES | INSULIN IMPROVES COGNITION | INTESTINAL ALKALINE-PHOSPHATASE | CENTRAL-NERVOUS-SYSTEM | GLYCATION END-PRODUCTS | AMYLOID PRECURSOR PROTEIN | MILD COGNITIVE IMPAIRMENT | CHARACTERISTIC TRANSKETOLASE ALTERATIONS | NEUROSCIENCES | A beta | POSITRON-EMISSION-TOMOGRAPHY | Glucose Transport Proteins, Facilitative - metabolism | Thiamine - metabolism | Humans | Oxidative Stress - physiology | Alzheimer Disease - metabolism | Alzheimer Disease - therapy | Biomarkers | Glucose - metabolism | Alzheimer Disease - chemically induced | Diabetes Mellitus, Type 2 - complications | Brain Chemistry - physiology | Glucose metabolism | Amyloid beta-protein | Physiological aspects | Glucose | Diagnosis | Health aspects | Dextrose | Age
Journal Article
Nature Reviews Neuroscience, ISSN 1471-003X, 03/2019, Volume 20, Issue 3, pp. 148 - 160
Alzheimer disease (AD) is a major cause of age-related dementia. We do not fully understand AD aetiology and pathogenesis, but oxidative damage is a key...
VITAMIN-E | LIPID-PEROXIDATION | AMYLOID-BETA-PEPTIDE | BRAIN INSULIN-RESISTANCE | DOWN-SYNDROME | MODIFIED PROTEINS | BILIVERDIN REDUCTASE-A | SOLUBLE OLIGOMERS | MILD COGNITIVE IMPAIRMENT | PROTEOMIC IDENTIFICATION | NEUROSCIENCES | Oxidative stress | Glucose metabolism | Care and treatment | Development and progression | Genetic aspects | Health aspects | Alzheimer's disease | Tricarboxylic acid cycle | Neurodegenerative diseases | Oxidative metabolism | Cognitive ability | Glucose | Metabolism | Glycolysis | Dementia disorders | Oxidation | Age
VITAMIN-E | LIPID-PEROXIDATION | AMYLOID-BETA-PEPTIDE | BRAIN INSULIN-RESISTANCE | DOWN-SYNDROME | MODIFIED PROTEINS | BILIVERDIN REDUCTASE-A | SOLUBLE OLIGOMERS | MILD COGNITIVE IMPAIRMENT | PROTEOMIC IDENTIFICATION | NEUROSCIENCES | Oxidative stress | Glucose metabolism | Care and treatment | Development and progression | Genetic aspects | Health aspects | Alzheimer's disease | Tricarboxylic acid cycle | Neurodegenerative diseases | Oxidative metabolism | Cognitive ability | Glucose | Metabolism | Glycolysis | Dementia disorders | Oxidation | Age
Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 06/2004, Volume 161, Issue 6, pp. 1038 - 1048
OBJECTIVE: Compulsive hoarding and saving symptoms, found in many patients with obsessive-compulsive disorder (OCD), are part of a discrete clinical syndrome...
BEHAVIOR-THERAPY | ANTERIOR CINGULATE CORTEX | FUNCTIONAL-ANATOMY | LA-TOURETTE-SYNDROME | PSYCHIATRY | POSITRON EMISSION TOMOGRAPHY | MEDIAL PREFRONTAL CORTEX | TREATMENT RESPONSE | CLINICAL-FEATURES | MAJOR DEPRESSION | SYMPTOM PROVOCATION | Severity of Illness Index | Brain - diagnostic imaging | Diagnosis, Differential | Humans | Middle Aged | Gyrus Cinguli - diagnostic imaging | Obsessive-Compulsive Disorder - metabolism | Gyrus Cinguli - metabolism | Brain - metabolism | Magnetic Resonance Imaging | Obsessive-Compulsive Disorder - diagnosis | Psychiatric Status Rating Scales | Obsessive-Compulsive Disorder - diagnostic imaging | Glucose - metabolism | Adult | Fluorodeoxyglucose F18 | Tomography, Emission-Computed | Glucose metabolism | Obsessive-compulsive disorder | Neuropsychology | Research
BEHAVIOR-THERAPY | ANTERIOR CINGULATE CORTEX | FUNCTIONAL-ANATOMY | LA-TOURETTE-SYNDROME | PSYCHIATRY | POSITRON EMISSION TOMOGRAPHY | MEDIAL PREFRONTAL CORTEX | TREATMENT RESPONSE | CLINICAL-FEATURES | MAJOR DEPRESSION | SYMPTOM PROVOCATION | Severity of Illness Index | Brain - diagnostic imaging | Diagnosis, Differential | Humans | Middle Aged | Gyrus Cinguli - diagnostic imaging | Obsessive-Compulsive Disorder - metabolism | Gyrus Cinguli - metabolism | Brain - metabolism | Magnetic Resonance Imaging | Obsessive-Compulsive Disorder - diagnosis | Psychiatric Status Rating Scales | Obsessive-Compulsive Disorder - diagnostic imaging | Glucose - metabolism | Adult | Fluorodeoxyglucose F18 | Tomography, Emission-Computed | Glucose metabolism | Obsessive-compulsive disorder | Neuropsychology | Research
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 2014, Volume 34, Issue 23, pp. 7862 - 7870
Dietary habits such as caloric restriction or nutrients that mimic these effects may exert beneficial effects on brain aging. The plant-derived polyphenol...
CR-mimetic | Aging | Resting-state fMRI | Microstructure | HbA1c | microstructure | BRAINS DEFAULT NETWORK | ALZHEIMERS-DISEASE | RATS | MILD COGNITIVE IMPAIRMENT | MRI MEASURES | NEUROSCIENCES | SUPPLEMENTATION | EPISODIC MEMORY | RESTING-STATE NETWORKS | MICE | resting-state fMRI | CALORIE RESTRICTION | Memory - drug effects | Stilbenes - administration & dosage | Follow-Up Studies | Glycated Hemoglobin A - metabolism | Humans | Leptin - metabolism | Middle Aged | Male | Hippocampus - drug effects | Cognition - drug effects | Case-Control Studies | Blood Glucose - drug effects | Neuropsychological Tests | Fasting - blood | Antioxidants - administration & dosage | Resveratrol | Aged, 80 and over | Quercetin - administration & dosage | Female | Aged
CR-mimetic | Aging | Resting-state fMRI | Microstructure | HbA1c | microstructure | BRAINS DEFAULT NETWORK | ALZHEIMERS-DISEASE | RATS | MILD COGNITIVE IMPAIRMENT | MRI MEASURES | NEUROSCIENCES | SUPPLEMENTATION | EPISODIC MEMORY | RESTING-STATE NETWORKS | MICE | resting-state fMRI | CALORIE RESTRICTION | Memory - drug effects | Stilbenes - administration & dosage | Follow-Up Studies | Glycated Hemoglobin A - metabolism | Humans | Leptin - metabolism | Middle Aged | Male | Hippocampus - drug effects | Cognition - drug effects | Case-Control Studies | Blood Glucose - drug effects | Neuropsychological Tests | Fasting - blood | Antioxidants - administration & dosage | Resveratrol | Aged, 80 and over | Quercetin - administration & dosage | Female | Aged
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2012, Volume 33, Issue 2, pp. 215 - 225
Abstract The authors investigated relationships between glucose metabolism, amyloid load, and measures of cognitive and functional impairment in Alzheimer's...
Neurology | Internal Medicine | Glucose metabolism | Dementia severity | Fluorodeoxyglucose | Pittsburgh Compound-B | Amyloidosis | Cognition | Alzheimer's disease | Amyloid plaques | NEUROFIBRILLARY TANGLES | LAYER III | PRECURSOR PROTEIN GENE | BETA-PEPTIDE | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | NEURITIC PLAQUES | POSITRON-EMISSION-TOMOGRAPHY | III PYRAMIDAL NEURONS | MACAQUE MONKEY | Alzheimer Disease - physiopathology | Cognition Disorders - physiopathology | Alzheimer Disease - complications | Brain - physiopathology | Humans | Male | Tissue Distribution | Cognition Disorders - etiology | Amyloid beta-Peptides - metabolism | Glucose - metabolism | Female | Aged | Neurosciences | PET imaging | Physiological aspects | Glucose | Dextrose
Neurology | Internal Medicine | Glucose metabolism | Dementia severity | Fluorodeoxyglucose | Pittsburgh Compound-B | Amyloidosis | Cognition | Alzheimer's disease | Amyloid plaques | NEUROFIBRILLARY TANGLES | LAYER III | PRECURSOR PROTEIN GENE | BETA-PEPTIDE | NEUROSCIENCES | GERIATRICS & GERONTOLOGY | NEURITIC PLAQUES | POSITRON-EMISSION-TOMOGRAPHY | III PYRAMIDAL NEURONS | MACAQUE MONKEY | Alzheimer Disease - physiopathology | Cognition Disorders - physiopathology | Alzheimer Disease - complications | Brain - physiopathology | Humans | Male | Tissue Distribution | Cognition Disorders - etiology | Amyloid beta-Peptides - metabolism | Glucose - metabolism | Female | Aged | Neurosciences | PET imaging | Physiological aspects | Glucose | Dextrose
Journal Article