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Journal of Basic and Applied Genetics, ISSN 1666-0390, 01/2017, Volume 28, p. 118
El cáncer de mama hereditario (CMH) representa un 5-10% de los casos de CM y está principalmente asociado a mutaciones en los genes BRCA1y BRCA2. Los pacientes... 
BRCA2 protein | BRCA1 protein
Journal Article
肿瘤防治研究, ISSN 1000-8578, 2017, Volume 44, Issue 9, pp. 622 - 626
Journal Article
07/2011
Background : Cell adhesion plays a pivotal role in diverse biological processes that occur in oncogenesis. BRCA1 was the first breast cancer susceptibility... 
BRCA1 | ligand binding
Web Resource
Bulletin du Cancer, ISSN 0007-4551, 11/2017, Volume 104, Issue 11, pp. 958 - 961
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2018, Volume 110, Issue 10, pp. 1133 - 1134
Journal Article
Gynécologie Obstétrique & Fertilité, ISSN 1297-9589, 12/2015, Volume 43, Issue 12, pp. 800 - 805
Les femmes indemnes porteuses de mutation des gènes  ou  peuvent-elles être considérées comme à risque d’altération prématurée de leur fertilité, et donc... 
Préservation de la fertilité | Fertility preservation | Menopause | Mutation BRCA1/2 | BRCA1/2 mutation | Réserve ovarienne | Ovarian reserve | Ménopause
Journal Article
肿瘤防治研究, ISSN 1000-8578, 2017, Volume 44, Issue 1, pp. 75 - 78
乳腺癌是女性最常见的恶性肿瘤,BRCA1/BRCA2是乳腺癌重要的易感基因,与遗传性乳腺癌的发生密切相关,目前BRCA基因突变型乳腺癌的靶向药物治疗是研究的热点。本文主要介绍BRCA基因在乳腺癌中的发生发展关系,并对其相关靶向治疗作一综述。 
乳腺癌 | 靶向治疗 | BRCA1 | BRCA2
Journal Article
膵臓, ISSN 0913-0071, 2018, Volume 33, Issue 6, pp. 944 - 948
Journal Article
by Tao, T and Yang, J X and Shen, K and Cao, D Y
Zhonghua fu chan ke za zhi, ISSN 0529-567X, 01/2017, Volume 52, Issue 1, p. 20
To compare the clinical and histological features and prognosis of patients with ovarian cancer from different genetic background, and to make further... 
Genetic Testing | Prognosis | Exons | Humans | Middle Aged | Male | Mutation - genetics | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Breast Neoplasms - genetics | Pedigree | Genes, BRCA2 | Adult | Female | Genes, BRCA1
Journal Article
BMB Reports, ISSN 1976-6696, 2013, Volume 46, Issue 2, p. 92
The breast cancer susceptibility gene BRCA1 encodes a nuclear protein, which functions as a tumor suppressor and is involved in gene transcription and DNA... 
DNA damage | Egr-1 | Etoposide | BRCA1 | Promoter activation
Journal Article
Journal of Gynecologic Oncology (JGO), ISSN 2005-0380, 2017, Volume 28, Issue 4, p. 1
Objective: To define genetic profiling of homologous recombination (HR) deficiency in Chinese ovarian cancer patients. Methods: We have applied next-generation... 
BRCA1; BRCA2; Homologous Recombination; Next-generation Sequencing; Epithelial Ovarian Cancer
Journal Article
Cancer / Radiothérapie, ISSN 1278-3218, 12/2014, Volume 18, Issue 8, pp. 790 - 798
La poly-ADP-ribosylation, assurée par les protéines de la famille des poly(ADP-ribose)polymérases (PARP), correspond à une modification post-traductionnelle de... 
Létalité synthétique | Chemotherapy | Radiothérapie | BRCA1/2 mutations | Mutations BRCA1/2 | PARP inhibitor | Chimiothérapie | Synthetic lethality | Radiotherapy | Inhibiteur de PARP
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 06/2011, Volume 127, Issue 2, pp. 417 - 427
Journal Article
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, ISSN 1436-9990, 3/2014, Volume 57, Issue 3, pp. 307 - 311
Die für Frauen der Allgemeinbevölkerung ohne ein familiär erhöhtes Brustkrebsrisiko zur Verfügung stehenden Brustkrebsfrüherkennungsuntersuchungen sind für die... 
Public Health | Familiäres Mammakarzinom | Medicine & Public Health | Surveillance | BRCA2 gene | General Practice / Family Medicine | Hereditary breast cancer | BRCA1 | BRCA2 | BRCA1 gene | Früherkennung
Journal Article
by Li, LL and Lu, MX and Lu, K and Liu, GB and Peng, L
CHINESE JOURNAL OF ORGANIC CHEMISTRY, ISSN 0253-2786, 01/2018, Volume 38, Issue 1, pp. 246 - 252
Peptide breast cancer susceptibility gene BRCA1 plays an active role in inhibiting female breast cancer. The interaction between BRCA1 and breast cancer... 
OLIGO-PEPTIDES | TEMPERATURE | BRCA1 peptide | fluorescence | DS simulation | DOCKING | CHEMISTRY, ORGANIC | RAD51 peptide | BINDING | CD spectroscopy
Journal Article
复旦学报:医学版, ISSN 1672-8467, 2017, Volume 44, Issue 3, pp. 312 - 318
目的 分析乳腺癌患者血亲亲属对遗传咨询和基因检测的了解和接受意愿。方法... 
基因检测 | 乳腺癌 | 遗传咨询 | BRCA1/2基因 | 血亲亲属
Journal Article
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