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Nature structural & molecular biology, ISSN 1545-9985, 05/2010, Volume 17, Issue 6, pp. 688 - 695
Journal Article
Nature communications, ISSN 2041-1723, 06/2018, Volume 9, Issue 1, pp. 1 - 14
...). Here, we identify the deubiquitylating enzyme USP48 as synthetic viable for FA-gene deficiencies by performing genome-wide loss-of-function screens across a panel of human haploid isogenic FA-defective cells... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phenotypes | Stability | Deactivation | BRCA1 protein | Anemia | Abnormalities | DNA damage | Genotoxicity | Health risks | Crosslinking | Breast cancer | Genomes | Inactivation | Fanconi syndrome | DNA repair | Screens | Genomic instability | FANCC protein | Bone cancer | Bone marrow | Repair | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
Journal Article
Breast cancer research and treatment, ISSN 1573-7217, 12/2017, Volume 168, Issue 3, pp. 625 - 630
Journal Article
Oncogene, ISSN 1476-5594, 11/2007, Volume 27, Issue 17, pp. 2501 - 2506
... mutation carriers, sporadic cases and familial non- BRCA1/ 2 patients. Our results show that ATM protein expression is aberrantly reduced more frequently among BRCA1 ( 33%; P 0.0003) and BRCA2 ( 30%; P 0.0009... 
Genetic instability | DNA damage response | ATM defects | BRCA1/BRCA2 familial cancer | Triple-negative breast cancer | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein-Serine-Threonine Kinases - deficiency | Receptors, Estrogen - metabolism | Tumor Suppressor Proteins - metabolism | Signal Transduction | Humans | Cell Cycle Proteins - metabolism | Receptor, ErbB-2 - metabolism | Tumor Suppressor Protein p53 - metabolism | Ataxia Telangiectasia Mutated Proteins | Receptors, Estrogen - deficiency | DNA-Binding Proteins - deficiency | Breast Neoplasms - metabolism | Receptors, Progesterone - metabolism | DNA-Binding Proteins - metabolism | Receptors, Progesterone - deficiency | BRCA2 Protein - metabolism | Breast Neoplasms - genetics | Tumor Suppressor Proteins - deficiency | BRCA1 Protein - metabolism | DNA Damage - genetics | BRCA2 Protein - deficiency | BRCA1 Protein - deficiency | Receptor, ErbB-2 - deficiency | Protein-Serine-Threonine Kinases - metabolism | Complications and side effects | Control | BRCA mutations | Ataxia telangiectasia | Genetic aspects | Breast cancer | Research | Health aspects | Risk factors | Signal transduction | Cellular biology | DNA damage | Kinases | Gene expression | Index Medicus
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 06/2014, Volume 211, Issue 6, pp. 1027 - 1036
Journal Article