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ACS Chemical Biology, ISSN 1554-8929, 11/2018, Volume 13, Issue 11, pp. 3054 - 3058
3-Bromopyruvate (3BP) is a potential anticancer agent viewed as a glycolytic inhibitor that preferentially kills cancer cells through inhibition of... 
INACTIVATION | SITE | ACID | MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTICANCER AGENT | ESCHERICHIA-COLI | CYSTEINE | LABEL | DEATH | BROMOPYRUVATE | Index Medicus
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 03/2019, Volume 20, Issue 6, p. 1292
This study aimed to examine whether inhibition of hexokinase (HK)-II activity enhances the efficacy of sorafenib in in-vivo models of hepatocellular carcinoma... 
Hepatocellular carcinoma | Hexokinase inhibitor | Bromopyruvate | Sorafenib | CELLS | sorafenib | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | MECHANISMS | INDUCTION | bromopyruvate | CHEMISTRY, MULTIDISCIPLINARY | ENHANCEMENT | RESISTANCE | 3-BROMOPYRUVATE | hexokinase inhibitor | ENERGY-METABOLISM | EXPRESSION | hepatocellular carcinoma | Index Medicus
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/2017, Volume 54, Issue 1, pp. 743 - 748
An efficient and novel approach to the synthesis of 1,2,3‐trisubstituted indolizines has been achieved via the reaction of pyridines, dialkyl... 
ROUTE | ETHYL BROMOPYRUVATE | LIBRARY | CHEMISTRY, ORGANIC | ALDEHYDES | EFFICIENT ONE-POT | DERIVATIVES | ESTROGEN-RECEPTOR | Pyridine
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2008, Volume 49, Issue 5, pp. 844 - 846
An efficient synthesis of ethyl 2-(4-acetyl-5-benzoylamino-3-methyl-2-thienyl)-2-oxoacetates is described via reaction between benzoyl isothiocyanates and... 
Benzoyl isothiocyanate | Thiophene | Ethyl bromopyruvate | Enaminone | ethyl bromopyruvate | HETEROCYCLES | thiophene | enaminone | benzoyl isothiocyanate | CHEMISTRY, ORGANIC | ACETYLENEDICARBOXYLATES
Journal Article
Biochemical Journal, ISSN 0264-6021, 02/2009, Volume 417, Issue 3, pp. 717 - 726
Journal Article
Phosphorus, Sulfur, and Silicon and the Related Elements, ISSN 1042-6507, 11/2015, Volume 190, Issue 11, pp. 1814 - 1819
A mild, convenient, and practical one-pot procedure for the direct synthesis of (1,2-dihydro-2-oxoquinoxaline-3-yl)methyl carbamodithioate derivatives is... 
(1,2-dihydro-2-oxoquinoxaline-3-yl)methyl carbamodith-ioate | one-pot reaction | secondary amine | Ethyl bromopyruvate | benzene-1,2-diamines
Journal Article
Journal of Chemical Research, ISSN 1747-5198, 12/2017, Volume 41, Issue 12, pp. 712 - 714
Some hitherto unreported thiazolo[3,4-a]quinoxaline derivatives have been synthesised in excellent yields via a one-pot, three-component reaction of... 
1,2-diaminobenzenes | Aryl isothiocyanates | Ethyl bromopyruvate | Thiazolo[3,4-a]quinoxalines | thiazolo[3,4-a]quinoxalines | NITROSTYRENE DERIVATIVES | aryl isothiocyanates | ethyl bromopyruvate | CHEMISTRY, MULTIDISCIPLINARY | Diamines | Quinoxalines | Chemical synthesis | Aromatic compounds | Benzene
Journal Article
Journal Article
Journal Article
Journal of Sulfur Chemistry, ISSN 1741-5993, 07/2018, Volume 39, Issue 4, pp. 414 - 421
A green and efficient one-pot three-component synthesis of some novel ethyl 3-alkyl-2-thioxo-2,3-dihydrothiazole-4-carboxylates from the reaction of primary... 
carbon disulfide | Ethyl bromopyruvate | multicomponent reaction | primary amines | 2-thioxo-2,3-dihydrothiazole | EFFICIENT SYNTHESIS | CARBON-DISULFIDE | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Solvents | Amines | Carbon disulfide | Catalysts | Catalysis | Chemical synthesis | Carboxylates
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 19, pp. 5881 - 5891
Purpose: MUC1, an oncogene overexpressed in multiple solid tumors, including pancreatic cancer, reduces overall survival and imparts resistance to radiation... 
RADIATION-RESISTANCE | CELLS | MUC1 | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | ADENOCARCINOMA | MOUSE MODEL | DNA-DAMAGE | INHIBITOR | TUMOR-GROWTH | EXPRESSION | Cell Proliferation - genetics | Pancreatic Neoplasms - metabolism | Humans | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - radiotherapy | Radiation Tolerance - genetics | Pancreatic Neoplasms - genetics | Gene Knockdown Techniques | Xenograft Model Antitumor Assays | Animals | Glycolysis - radiation effects | Cell Line, Tumor | Glucose - metabolism | Gene Expression Regulation, Neoplastic - radiation effects | Mice | Signal Transduction - radiation effects | DNA Damage - radiation effects | Cell Proliferation - radiation effects | Mucin-1 - genetics | Phosphates | Cell culture | Toxicity | DNA damage | Radiation | Cytotoxicity | Biosynthesis | Alterations | Pentose | Biocompatibility | Inhibition | Pretreatment | Deoxyribonucleic acid--DNA | Pentose phosphate | Radiation effects | Damage assessment | Radiation therapy | Tumor cell lines | Metabolism | Pools | Gene expression | Studies | Experimental design | Pancreatic cancer | Cell lines | Pentose phosphate pathway | Radiation tolerance | Glycolysis | Solid tumors | Radiation damage | Tumors | Cancer | Index Medicus | cancer metabolism | pancreatic cancer | mucin | radiation resistance | nucleotide metabolism | bromopyruvate
Journal Article
Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 03/2013, Volume 9, Issue 1, pp. 510 - 515
Journal Article
Synthetic Communications, ISSN 0039-7911, 01/2014, Volume 44, Issue 1, pp. 76 - 81
The three-component reactions of phenanthridine, activated acetylenes, and ethyl bromopyruvate through both of simultaneous and stepwise process are surveyed.... 
three-component reactions | pyrrolo[1,2-f]phenanthridines | Ethyl bromopyruvate | phenanthridine | 2-f]phenanthridines | ANALOGS | AZOMETHINE YLIDES | CHEMISTRY, ORGANIC | pyrrolo | AGENTS | DIMETHYL ACETYLENEDICARBOXYLATE
Journal Article
BBA - Proteins and Proteomics, ISSN 1570-9639, 11/2016, Volume 1864, Issue 11, pp. 1506 - 1517
Journal Article
Journal Article