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Journal Article
Nature (London), ISSN 1476-4687, 04/2010, Volume 464, Issue 7289, pp. 728 - 732
African sleeping sickness or human African trypanosomiasis, caused by Trypanosoma brucei spp., is responsible for approximately 30,000 deaths each year.... 
Acyltransferases - antagonists & inhibitors | Trypanosomiasis, African - drug therapy | Pyrazoles - therapeutic use | Humans | Antiparasitic Agents - metabolism | Aminopyridines - metabolism | Acyltransferases - metabolism | Trypanosoma brucei brucei - enzymology | Aminopyridines - chemistry | Pyrazoles - chemistry | Aminopyridines - therapeutic use | Time Factors | Enzyme Inhibitors - chemistry | Female | Molecular Structure | Trypanosoma brucei brucei - growth & development | Pyrazoles - pharmacology | Enzyme Inhibitors - metabolism | Sulfonamides - chemistry | Enzyme Inhibitors - pharmacology | Rats | Enzyme Assays | Pyrazoles - metabolism | Sulfonamides - pharmacology | Enzyme Inhibitors - therapeutic use | Trypanosoma brucei brucei - drug effects | Antiparasitic Agents - therapeutic use | Trypanosomiasis, African - parasitology | Animals | Sulfonamides - therapeutic use | Aminopyridines - pharmacology | Antiparasitic Agents - pharmacology | Sulfonamides - metabolism | Mice | Antiparasitic Agents - chemistry | Post-translational modification | Usage | Control | Care and treatment | Enzyme inhibitors | Transferases | Physiological aspects | Genetic aspects | Research | Health aspects | Trypanosomiasis | Proteins | Data collection | Enzymes | Human | Inhibitors | Peptides | Central nervous system | Sicknesses | Trypanosome | Index Medicus | PARASITES | TRYPANOSOMIASIS | BASIC BIOLOGICAL SCIENCES | SAFETY | SUBSTRATES | VALIDATION | CENTRAL NERVOUS SYSTEM | IN VIVO | 60 APPLIED LIFE SCIENCES | DISEASES | PEPTIDES | TRYPANOSOMA | ENZYMES | IN VITRO | DRUGS | TARGETS | MICE | PROTEINS | TRYPANOSOMES | LEAD COMPOUNDS
Journal Article