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American Journal of Surgical Pathology, ISSN 0147-5185, 03/2010, Volume 34, Issue 3, pp. 327 - 340
B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements, also known as "double-hit'' lymphomas (DHL), are rare neoplasms characterized by highly... 
BCL2 | Cytogenetics | High-grade B-cell lymphoma | MYC | Burkitt lymphoma | Diffuse large B-cell lymphoma | high-grade B-cell lymphoma | TRANSFORMATION | SURGERY | TRANSLOCATION | T(14/18) | T(14-18) | C-MYC | FOLLICULAR LYMPHOMA | diffuse large B-cell lymphoma | PATHOLOGY | cytogenetics | POLYMERASE-CHAIN-REACTION | ACUTE LYMPHOBLASTIC-LEUKEMIA | EXPRESSION | Predictive Value of Tests | Humans | Lymphoma, B-Cell - therapy | Middle Aged | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Male | Lymphoma, B-Cell - genetics | Burkitt Lymphoma - mortality | Burkitt Lymphoma - pathology | Genes, Immunoglobulin Heavy Chain | Young Adult | Lymphoma, Large B-Cell, Diffuse - therapy | Time Factors | Karyotyping | Polymerase Chain Reaction | Aged, 80 and over | Burkitt Lymphoma - genetics | Adult | Female | Retrospective Studies | Child | Burkitt Lymphoma - therapy | Lymphoma, B-Cell - mortality | World Health Organization | Burkitt Lymphoma - classification | Lymphoma, Large B-Cell, Diffuse - pathology | Risk Assessment | Kaplan-Meier Estimate | Proportional Hazards Models | Antineoplastic Combined Chemotherapy Protocols | Terminology as Topic | Immunophenotyping | In Situ Hybridization, Fluorescence | Treatment Outcome | Lymphoma, B-Cell - classification | Lymphoma, Large B-Cell, Diffuse - mortality | Gene Rearrangement, B-Lymphocyte, Heavy Chain | Lymphoma, Large B-Cell, Diffuse - classification | Adolescent | Lymphoma, B-Cell - pathology | Aged | Proto-Oncogene Proteins c-myc - genetics | Neoplasm Staging | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-2 - genetics
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7418, pp. 116 - 120
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 11, pp. 2273 - 2279
Journal Article
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9822, pp. 1234 - 1244
Summary Burkitt's lymphoma is a highly aggressive B-cell non-Hodgkin lymphoma and is the fastest growing human tumour. The disease is associated with... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | AFRICAN CHILDREN | PLASMODIUM-FALCIPARUM | ACUTE LYMPHOBLASTIC-LEUKEMIA | B-CELL LYMPHOMAS | ACTIVE ANTIRETROVIRAL THERAPY | C-MYC | NON-HODGKINS-LYMPHOMA | EPSTEIN-BARR-VIRUS | CHILDRENS ONCOLOGY GROUP | ACUTE MALARIA | Transcriptional Activation - genetics | Prognosis | HIV Infections - epidemiology | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Child, Preschool | Infant | Burkitt Lymphoma - epidemiology | Incidence | Endemic Diseases | Malaria - epidemiology | Burkitt Lymphoma - genetics | Epstein-Barr Virus Infections - genetics | Child | Burkitt Lymphoma - drug therapy | Epstein-Barr Virus Infections - epidemiology | Poverty - statistics & numerical data | Health Services Accessibility - statistics & numerical data | Burkitt Lymphoma - virology | Cross-Sectional Studies | Epstein-Barr Virus Infections - virology | Risk Factors | Rituximab | Epstein-Barr Virus Infections - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Proto-Oncogene Proteins c-myc - genetics | Translocation, Genetic - genetics | Care and treatment | Immunocompromised host | Patient outcomes | Genetic aspects | Risk factors | Burkitt's lymphoma | Diseases | Causes of | Practice guidelines (Medicine) | Diagnosis | Low income groups | Chemotherapy | Consolidation | Malaria | Human immunodeficiency virus--HIV | Cyclin-dependent kinases | Drug therapy | Epidemiology | Cancer therapies | Cancer | Apoptosis | Tumors
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2006, Volume 354, Issue 23, pp. 2431 - 2442
Journal Article
Haematologica, ISSN 0390-6078, 04/2014, Volume 99, Issue 4, pp. 726 - 735
Journal Article
Cancer, ISSN 0008-543X, 10/2012, Volume 118, Issue 19, pp. 4715 - 4724
Journal Article
The American Journal of Surgical Pathology, ISSN 0147-5185, 02/2018, Volume 42, Issue 2, pp. 269 - 276
Isolated MYC rearrangement without other recurrent genetic abnormalities is rare in B lymphoblastic leukemia/lymphoma (B-ALL/LBL), with most cases reported in... 
B lymphoblastic leukemia/lymphoma | MYC rearrangement | Gene (TdT) rearrangement | Terminal deoxynucleotidyl transferase | Burkitt lymphoma | TRANSFORMATION | SURGERY | TRANSLOCATION | lymphoma | FOLLICULAR LYMPHOMA | PATHOLOGY | LOCUS | gene (TdT) rearrangement | MOLECULAR ANALYSIS | terminal deoxynucleotidyl transferase | SURFACE | B lymphoblastic leukemia | CELL IMMUNOPHENOTYPE | LEUKEMIA | Immunohistochemistry | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Humans | Middle Aged | Male | Burkitt Lymphoma - pathology | Genes, Immunoglobulin Heavy Chain | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - immunology | Flow Cytometry | Burkitt Lymphoma - immunology | Burkitt Lymphoma - genetics | Adult | Immunophenotyping - methods | Cell Differentiation | Burkitt Lymphoma - therapy | Genetic Predisposition to Disease | Biomarkers, Tumor - analysis | In Situ Hybridization, Fluorescence | Treatment Outcome | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Phenotype | Gene Rearrangement, B-Lymphocyte, Heavy Chain | Aged | Biomarkers, Tumor - genetics | Proto-Oncogene Proteins c-myc - genetics | Care and treatment | Translocation (Genetics) | Oncology, Experimental | Development and progression | Genetic aspects | Research | Health aspects | Burkitt's lymphoma | Cancer
Journal Article
British Journal of Haematology, ISSN 0007-1048, 11/2014, Volume 167, Issue 3, pp. 394 - 401
Summary Children and adolescents with Burkitt Lymphoma (BL) and combined central nervous system (CNS) and bone marrow involvement still have a poor prognosis... 
Burkitt leukaemia | children | chemotherapy | rituximab | Burkitt lymphoma | Rituximab | Chemotherapy | Children | ACUTE-LYMPHOBLASTIC-LEUKEMIA | PLUS RITUXIMAB | PHASE-II | RISK | ADULT BURKITT | B-CELL LYMPHOMA | CODOX-M/IVAC | THERAPY | NON-HODGKINS-LYMPHOMA | INTERMEDIATE | HEMATOLOGY | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Consolidation Chemotherapy | Cytarabine - adverse effects | Genes, myc | Typhlitis - chemically induced | Lymphoma, B-Cell - genetics | Cyclophosphamide - adverse effects | Immunotherapy | Burkitt Lymphoma - genetics | Vincristine - administration & dosage | Female | Maintenance Chemotherapy | Child | Burkitt Lymphoma - drug therapy | Doxorubicin - administration & dosage | Lymphoma, B-Cell - drug therapy | Prednisone - administration & dosage | Etoposide - adverse effects | Prednisone - adverse effects | Drug Administration Schedule | Kaplan-Meier Estimate | Etoposide - administration & dosage | Remission Induction | Cytarabine - administration & dosage | Disease-Free Survival | Methotrexate - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Bone Marrow - pathology | Adolescent | Vincristine - adverse effects | Methotrexate - administration & dosage | Infusions, Intravenous | Antibodies, Monoclonal, Murine-Derived - adverse effects | Central Nervous System Neoplasms - drug therapy | Doxorubicin - adverse effects | Lymphomas | Leukemia | Central nervous system | Cancer
Journal Article