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PLoS Pathogens, ISSN 1553-7366, 05/2011, Volume 7, Issue 5, p. e1002027
During infection Neisseria meningitidis (Nm) encounters multiple environments within the host, which makes rapid adaptation a crucial factor for meningococcal... 
HUMAN EPITHELIAL-CELLS | FACTOR-H-BINDING | MICROBIOLOGY | SEROGROUP-B MENINGOCOCCUS | GENOME | PATHOGENIC NEISSERIAE | VACCINE CANDIDATES | VIROLOGY | OUTER-MEMBRANE PROTEIN | GENE-EXPRESSION | STAPHYLOCOCCUS-AUREUS | SERINE-PROTEASE | PARASITOLOGY | Adaptation, Physiological | Sequence Deletion | Virulence Factors - genetics | Genes, Bacterial - genetics | Humans | Neisseria meningitidis, Serogroup B - physiology | Transcriptome | Male | Neisseria meningitidis, Serogroup B - genetics | Meningococcal Infections - microbiology | Antigens, Bacterial - genetics | Bacteremia - microbiology | Bacteremia - blood | RNA, Bacterial - genetics | Adult | Female | Neisseria meningitidis, Serogroup B - pathogenicity | Bacterial Proteins - genetics | Up-Regulation - genetics | Down-Regulation - genetics | Neisseria meningitidis, Serogroup B - growth & development | Genome, Bacterial - genetics | Gene Expression Regulation, Bacterial - genetics | Host-Pathogen Interactions - genetics | Models, Biological | Meningococcal Infections - blood | Cluster Analysis | Causes of | Sepsis | Neisseria meningitidis | Genetic aspects | Research | Health aspects | Microbiology | Pathogenesis | Mortality | Genomes | Gene expression | Blood | Proteins | Studies | Evolutionary biology | Mutagenesis | DNA methylation | Meningitis | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | DNA
Journal Article
PLoS genetics, ISSN 1553-7390, 10/2018, Volume 14, Issue 10, p. e1007667
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2017, Volume 127, Issue 12, pp. 4415 - 4420
Primary immunodeficiencies are often monogenic disorders characterized by vulnerability to specific infectious pathogens. Here, we performed whole-exome... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | ACTIVATOR | INTERFERON-GAMMA | MYCOBACTERIAL DISEASE | ALPHA/BETA | MENDELIAN SUSCEPTIBILITY | CLINICAL-FEATURES | DEFICIENCY | SIGNAL TRANSDUCER | INBORN-ERRORS | Bacteremia - immunology | Genetic Diseases, Inborn - microbiology | STAT2 Transcription Factor - immunology | Humans | Genetic Diseases, Inborn - genetics | Genetic Diseases, Inborn - virology | Male | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Bacteremia - microbiology | Streptococcal Infections - genetics | Phosphorylation - genetics | Female | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Fibroblasts - microbiology | Mycobacterium Infections, Nontuberculous - immunology | Immunologic Deficiency Syndromes - immunology | Receptors, Interferon - genetics | Fibroblasts - virology | Genetic Diseases, Inborn - immunology | Viremia - genetics | Viridans Streptococci - immunology | Bacteremia - genetics | Immunologic Deficiency Syndromes - virology | STAT1 Transcription Factor - genetics | Immunologic Deficiency Syndromes - microbiology | STAT1 Transcription Factor - immunology | Cytomegalovirus - immunology | Mycobacterium abscessus - immunology | Receptor, Interferon alpha-beta - immunology | Receptors, Interferon - immunology | Viremia - virology | STAT2 Transcription Factor - genetics | Immunologic Deficiency Syndromes - genetics | Fibroblasts - immunology | Viremia - immunology | Streptococcal Infections - immunology | Mutation | Mycobacterium Infections, Nontuberculous - genetics | Virus diseases | Usage | Immunotherapy | Genetic aspects | Disease susceptibility | Research | Mutation (Biology) | Stat2 protein | Cytomegalovirus | Phosphorylation | Viremia | Immunodeficiency | Stop codon | C-Terminus | Gene deletion | Bacteremia | Nuclear transport | α-Interferon | Clonal deletion | Fibroblasts | Interferon | Codons | Stat1 protein | Viral infections
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2010, Volume 6, Issue 9, p. e1001125
Although polymicrobial infections, caused by combinations of viruses, bacteria, fungi and parasites, are being recognised with increasing frequency, little is... 
POLYCLONAL BACTEREMIA | MULTICELLULAR BEHAVIOR | SINGLE ORGANISM | MICROBIOLOGY | FRAGMENT-LENGTH-POLYMORPHISM | GENETIC DIVERSITY | STATIONARY-PHASE | VIROLOGY | PSEUDOMONAS-AERUGINOSA | CYSTIC-FIBROSIS | GROWTH-PHASE | PARASITOLOGY | RNA-POLYMERASE | Sigma Factor - metabolism | Oxidants - pharmacology | Virulence Factors - genetics | Humans | Electrophoresis, Gel, Two-Dimensional | Immunoblotting | Genetic Variation | Microbial Sensitivity Tests | Escherichia coli Infections - genetics | Virulence - genetics | Escherichia coli - pathogenicity | Polymerase Chain Reaction | Adult | Female | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Drug Resistance, Bacterial - genetics | Sigma Factor - genetics | Models, Theoretical | Genome, Bacterial | Bacterial Proteins - genetics | Hydrogen Peroxide - pharmacology | Escherichia coli Infections - microbiology | Genotype | Mutation - genetics | Biological Evolution | Escherichia coli Infections - epidemiology | Animals | DNA, Bacterial - genetics | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Mice | Cell Movement | Escherichia coli - classification | Molecular evolution | Bacterial infections | Gastrointestinal diseases | Escherichia coli | Colorectal diseases | Genetic aspects | Research | Bacterial genetics | Health aspects | Escherichia coli/classification | Hydrogen Peroxide/pharmacology | Escherichia coli/pathogenicity | Escherichia coli Infections/genetics | Anti-Bacterial Agents/pharmacology | Virulence Factors/genetics | Virulence/genetics | Life Sciences | Sigma Factor/metabolism | Escherichia coli Proteins/genetics | Oxidants/pharmacology | Mutation/genetics | Escherichia coli/genetics | Escherichia coli Infections/epidemiology | Bacteriology | Microbiology and Parasitology | Bacterial Proteins/metabolism | Bacterial Proteins/genetics | Drug Resistance, Bacterial/genetics | Sigma Factor/genetics | Escherichia coli Infections/microbiology | DNA, Bacterial/genetics | Microbiology | Cloning | Infections | Experiments | Patients | Molecular weight | Antibiotics | E coli | Bacteria | Evolution | Mathematical models | Mutation
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2007, Volume 39, Issue 4, pp. 523 - 528
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4693 - 4700
Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive... 
INFECTIOUS DISEASES | PATHOGENIC LEPTOSPIRA | LETHAL INFECTION | IN-VIVO | DISEASE | HOST | IMMUNOLOGY | SEROVAR ICTEROHAEMORRHAGIAE | RENAL COLONIZATION | C3H/HEJ MICE | T-CELLS | BRAZIL | Mice - immunology | Bacteremia - immunology | Kidney - pathology | Tumor Necrosis Factor-alpha - genetics | Bacteriuria - microbiology | Hypothermia - immunology | Interleukin-1beta - genetics | Immunoglobulin G - biosynthesis | Tumor Necrosis Factor-alpha - immunology | Hypothermia - microbiology | Leptospirosis - immunology | Chemokines - immunology | Disease Models, Animal | Mice - genetics | Interleukin-6 - genetics | Signal Transduction | Chemokines - genetics | Leptospira interrogans - immunology | Host-Pathogen Interactions | Bacteriuria - pathology | Kidney - microbiology | Chemokine CXCL2 - immunology | Leptospirosis - pathology | Chemokine CCL5 - genetics | Interleukin-6 - immunology | Bacteremia - pathology | Chronic Disease | Hypothermia - genetics | Bacteriuria - genetics | Kidney - immunology | Hypothermia - pathology | Bacteremia - microbiology | Nitric Oxide Synthase Type II - immunology | Weight Loss - immunology | Chemokine CXCL2 - genetics | Female | CD4-Positive T-Lymphocytes | Interferon-gamma - genetics | Leptospirosis - microbiology | Mice - microbiology | Bacteriuria - immunology | Gene Expression Regulation | Interleukin-1beta - immunology | Bacteremia - genetics | Mice, Inbred C3H | Leptospirosis - genetics | Animals | Nitric Oxide Synthase Type II - genetics | Interferon-gamma - immunology | Chemokine CCL5 - immunology | Bacterial Infections
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 3, p. e1003979
Journal Article
Infection and Immunity, ISSN 0019-9567, 2017, Volume 85, Issue 11
Alcohol abuse impairs immune defense. To study the effect of chronicplus-binge alcohol exposure on the granulopoietic response, acute alcohol intoxication... 
Alcohol | Granulopoietic response | Granulocytes | Bacteremia | Cell signaling | Stem cells | granulocytes | PROGENITOR CELLS | MORTALITY | stem cells | INFECTIOUS DISEASES | ESCHERICHIA-COLI BACTEREMIA | BONE-MARROW | granulopoietic response | NEUTROPHILS | IMMUNOLOGY | STEM | DEPENDENCE | LIVER-INJURY | cell signaling | INFECTION | EXPRESSION | bacteremia | Bacteremia - immunology | Binge Drinking - pathology | Male | Proto-Oncogene Proteins c-kit - immunology | Hematopoiesis - drug effects | Escherichia coli Infections - genetics | Nucleotidyltransferases - deficiency | Bone Marrow Cells - immunology | Mitogen-Activated Protein Kinase 1 - genetics | Granulocytes - pathology | Disease Models, Animal | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Bone Marrow Cells - pathology | Toll-Like Receptor 4 - genetics | Hematopoiesis - genetics | Toll-Like Receptor 4 - immunology | Hematopoiesis - immunology | Cyclin D1 - immunology | Cyclin D1 - genetics | Escherichia coli Infections - pathology | Signal Transduction - drug effects | CCAAT-Enhancer-Binding Protein-beta - immunology | Escherichia coli Infections - immunology | Mice | Mice, Inbred BALB C | Bacteremia - pathology | Antigens, Ly - genetics | Binge Drinking - immunology | Signal Transduction - immunology | Granulocytes - drug effects | Bone Marrow Cells - drug effects | Proto-Oncogene Proteins c-kit - genetics | Escherichia coli - growth & development | Mitogen-Activated Protein Kinase 3 - immunology | Gene Expression Regulation - immunology | Escherichia coli - immunology | Membrane Proteins - immunology | Bacteremia - genetics | Binge Drinking - genetics | Gene Expression Regulation - drug effects | Ethanol - pharmacology | Animals | Antigens, Ly - immunology | Nucleotidyltransferases - genetics | Nucleotidyltransferases - immunology | Granulocytes - immunology | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0135579 - e0135579
Staphylococcus aureus is an important pathogen manifesting virulence through diverse disease forms, ranging from acute skin infections to life-threatening... 
SIGNAL-TRANSDUCTION | PATHOGENICITY ISLANDS | FIBRONECTIN-BINDING PROTEINS | ALPHA-HEMOLYSIN | MULTIDISCIPLINARY SCIENCES | NASAL COLONIZATION | GLOBAL REGULATION | GENE-EXPRESSION | 2-COMPONENT SYSTEM | VIRULENCE-DETERMINANT EXPRESSION | ENVIRONMENTAL-FACTORS | Sigma Factor - metabolism | Genomic Islands - genetics | Bacterial Proteins - genetics | Repressor Proteins - genetics | DNA-Binding Proteins - genetics | Promoter Regions, Genetic - genetics | Superantigens - metabolism | DNA-Binding Proteins - metabolism | Bacterial Toxins - metabolism | Enterotoxins - genetics | Gene Expression Regulation, Bacterial - genetics | Superantigens - genetics | Trans-Activators - genetics | Enterotoxins - metabolism | Bacterial Proteins - metabolism | Bacterial Toxins - genetics | Trans-Activators - metabolism | Sigma Factor - genetics | Repressor Proteins - metabolism | Staphylococcus aureus - metabolism | Septic shock | Virulence (Microbiology) | Health aspects | Staphylococcus aureus | Regulations | Regulators | Phosphorylation | Transcription | Gene regulation | Virulence | Sigma factor | Kinases | Drug resistance | Medical schools | Toxic shock syndrome | Clonal deletion | Deletion | Pathogens | Metabolism | Gene expression | Environmental impact | Bacteremia | Environmental effects | Strain | Pathogenicity | Medicine | Infectious diseases | Hospitals | Antibiotics | Rot | Staphylococcal enterotoxin F | Index Medicus
Journal Article