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Infection and Immunity, ISSN 0019-9567, 2017, Volume 85, Issue 11
Alcohol abuse impairs immune defense. To study the effect of chronicplus-binge alcohol exposure on the granulopoietic response, acute alcohol intoxication... 
Alcohol | Granulopoietic response | Granulocytes | Bacteremia | Cell signaling | Stem cells | granulocytes | PROGENITOR CELLS | MORTALITY | stem cells | INFECTIOUS DISEASES | ESCHERICHIA-COLI BACTEREMIA | BONE-MARROW | granulopoietic response | NEUTROPHILS | IMMUNOLOGY | STEM | DEPENDENCE | LIVER-INJURY | cell signaling | INFECTION | EXPRESSION | bacteremia | Bacteremia - immunology | Binge Drinking - pathology | Male | Proto-Oncogene Proteins c-kit - immunology | Hematopoiesis - drug effects | Escherichia coli Infections - genetics | Nucleotidyltransferases - deficiency | Bone Marrow Cells - immunology | Mitogen-Activated Protein Kinase 1 - genetics | Granulocytes - pathology | Disease Models, Animal | Mitogen-Activated Protein Kinase 1 - immunology | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Bone Marrow Cells - pathology | Toll-Like Receptor 4 - genetics | Hematopoiesis - genetics | Toll-Like Receptor 4 - immunology | Hematopoiesis - immunology | Cyclin D1 - immunology | Cyclin D1 - genetics | Escherichia coli Infections - pathology | Signal Transduction - drug effects | CCAAT-Enhancer-Binding Protein-beta - immunology | Escherichia coli Infections - immunology | Mice | Mice, Inbred BALB C | Bacteremia - pathology | Antigens, Ly - genetics | Binge Drinking - immunology | Signal Transduction - immunology | Granulocytes - drug effects | Bone Marrow Cells - drug effects | Proto-Oncogene Proteins c-kit - genetics | Escherichia coli - growth & development | Mitogen-Activated Protein Kinase 3 - immunology | Gene Expression Regulation - immunology | Escherichia coli - immunology | Membrane Proteins - immunology | Bacteremia - genetics | Binge Drinking - genetics | Gene Expression Regulation - drug effects | Ethanol - pharmacology | Animals | Antigens, Ly - immunology | Nucleotidyltransferases - genetics | Nucleotidyltransferases - immunology | Granulocytes - immunology | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2017, Volume 127, Issue 12, pp. 4415 - 4420
Primary immunodeficiencies are often monogenic disorders characterized by vulnerability to specific infectious pathogens. Here, we performed whole-exome... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | ACTIVATOR | INTERFERON-GAMMA | MYCOBACTERIAL DISEASE | ALPHA/BETA | MENDELIAN SUSCEPTIBILITY | CLINICAL-FEATURES | DEFICIENCY | SIGNAL TRANSDUCER | INBORN-ERRORS | Bacteremia - immunology | Genetic Diseases, Inborn - microbiology | STAT2 Transcription Factor - immunology | Humans | Genetic Diseases, Inborn - genetics | Genetic Diseases, Inborn - virology | Male | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - genetics | Bacteremia - microbiology | Streptococcal Infections - genetics | Phosphorylation - genetics | Female | Phosphorylation - immunology | Receptor, Interferon alpha-beta - genetics | Fibroblasts - microbiology | Mycobacterium Infections, Nontuberculous - immunology | Immunologic Deficiency Syndromes - immunology | Receptors, Interferon - genetics | Fibroblasts - virology | Genetic Diseases, Inborn - immunology | Viremia - genetics | Viridans Streptococci - immunology | Bacteremia - genetics | Immunologic Deficiency Syndromes - virology | STAT1 Transcription Factor - genetics | Immunologic Deficiency Syndromes - microbiology | STAT1 Transcription Factor - immunology | Cytomegalovirus - immunology | Mycobacterium abscessus - immunology | Receptor, Interferon alpha-beta - immunology | Receptors, Interferon - immunology | Viremia - virology | STAT2 Transcription Factor - genetics | Immunologic Deficiency Syndromes - genetics | Fibroblasts - immunology | Viremia - immunology | Streptococcal Infections - immunology | Mutation | Mycobacterium Infections, Nontuberculous - genetics | Virus diseases | Usage | Immunotherapy | Genetic aspects | Disease susceptibility | Research | Mutation (Biology) | Stat2 protein | Cytomegalovirus | Phosphorylation | Viremia | Immunodeficiency | Stop codon | C-Terminus | Gene deletion | Bacteremia | Nuclear transport | α-Interferon | Clonal deletion | Fibroblasts | Interferon | Codons | Stat1 protein | Viral infections | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2016, Volume 196, Issue 8, pp. 3364 - 3374
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4693 - 4700
Although Leptospira can infect a wide range of mammalian species, most studies have been conducted in golden Syrian hamsters, a species particularly sensitive... 
INFECTIOUS DISEASES | PATHOGENIC LEPTOSPIRA | LETHAL INFECTION | IN-VIVO | DISEASE | HOST | IMMUNOLOGY | SEROVAR ICTEROHAEMORRHAGIAE | RENAL COLONIZATION | C3H/HEJ MICE | T-CELLS | BRAZIL | Mice - immunology | Bacteremia - immunology | Kidney - pathology | Tumor Necrosis Factor-alpha - genetics | Bacteriuria - microbiology | Hypothermia - immunology | Interleukin-1beta - genetics | Immunoglobulin G - biosynthesis | Tumor Necrosis Factor-alpha - immunology | Hypothermia - microbiology | Leptospirosis - immunology | Chemokines - immunology | Disease Models, Animal | Mice - genetics | Interleukin-6 - genetics | Signal Transduction | Chemokines - genetics | Leptospira interrogans - immunology | Host-Pathogen Interactions | Bacteriuria - pathology | Kidney - microbiology | Chemokine CXCL2 - immunology | Leptospirosis - pathology | Chemokine CCL5 - genetics | Interleukin-6 - immunology | Bacteremia - pathology | Chronic Disease | Hypothermia - genetics | Bacteriuria - genetics | Kidney - immunology | Hypothermia - pathology | Bacteremia - microbiology | Nitric Oxide Synthase Type II - immunology | Weight Loss - immunology | Chemokine CXCL2 - genetics | Female | CD4-Positive T-Lymphocytes | Interferon-gamma - genetics | Leptospirosis - microbiology | Mice - microbiology | Bacteriuria - immunology | Gene Expression Regulation | Interleukin-1beta - immunology | Bacteremia - genetics | Mice, Inbred C3H | Leptospirosis - genetics | Animals | Nitric Oxide Synthase Type II - genetics | Interferon-gamma - immunology | Chemokine CCL5 - immunology | Index Medicus | Bacterial Infections
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 12, pp. 2331 - 2339
Journal Article
Immunity, ISSN 1074-7613, 2009, Volume 31, Issue 6, pp. 974 - 985
Immunity to in humans and in mice requires interferon gamma (IFN-γ). Whereas IFN-γ has been studied extensively for its effects on macrophages in tuberculosis,... 
MOLIMMUNO | CELLIMMUNO | MACROPHAGE RESPONSES | HUMAN-FIBROBLASTS | DENDRITIC CELLS | TRYPTOPHAN-METABOLITES | NITRIC-OXIDE SYNTHASE | LUNG EPITHELIAL-CELLS | IFN-GAMMA | INDOLEAMINE 2,3-DIOXYGENASE | ENDOTHELIAL-CELLS | TOXOPLASMA-GONDII | IMMUNOLOGY | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | T-Lymphocytes, Helper-Inducer - microbiology | Bacteremia - immunology | Lung - microbiology | Oligonucleotide Array Sequence Analysis | Mycobacterium tuberculosis - immunology | Gene Expression Profiling | Interferon-gamma - metabolism | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Bacteremia - microbiology | Endothelial Cells - microbiology | Respiratory Mucosa - pathology | Respiratory Mucosa - microbiology | Interleukin-23 - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Respiratory Mucosa - immunology | Female | Tuberculosis, Pulmonary - enzymology | Kynurenine - metabolism | Receptors, Interferon - genetics | Neutrophil Infiltration - immunology | Lung - pathology | Mice, Inbred C57BL | Pneumonia, Bacterial - enzymology | Cells, Cultured | Interleukin-23 - immunology | Mice, Knockout | Endothelial Cells - immunology | Interleukin-17 - metabolism | Tuberculosis, Pulmonary - immunology | Animals | Pneumonia, Bacterial - immunology | Mice | Endothelial Cells - pathology | Kynurenine - immunology | Lung - immunology | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 11/2014, Volume 41, Issue 5, pp. 789 - 801
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2007, Volume 178, Issue 5, pp. 3126 - 3133
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2014, Volume 192, Issue 8, pp. 3740 - 3752
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 05/2012, Volume 302, Issue 10, pp. 1003 - 1013
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