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Nature (London), ISSN 0028-0836, 2018, Volume 559, Issue 7713, pp. 259 - 263
...). Drug combinations can help to fight multi-drug-resistant bacterial infections, yet they are largely unexplored and rarely used in clinics... 
OUTER-MEMBRANE | AMINOGLYCOSIDES | BACTERIA | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | ANTIBIOTIC-RESISTANCE | INTERACTION NETWORKS | AZITHROMYCIN | ACCUMULATION | DISCOVERY | Moths - microbiology | Species Specificity | Escherichia coli - drug effects | Phylogeny | Microbial Sensitivity Tests | Colistin - pharmacology | Drug Interactions | Larva - drug effects | Salmonella typhimurium - classification | Salmonella typhimurium - drug effects | Drug Resistance, Microbial - drug effects | Benzaldehydes - pharmacology | Pseudomonas aeruginosa - drug effects | Food Additives - pharmacology | Drug Synergism | Gram-Negative Bacteria - drug effects | Moths - growth & development | Animals | Anti-Bacterial Agents - pharmacology | Larva - microbiology | Pseudomonas aeruginosa - classification | Drug Resistance, Multiple, Bacterial - drug effects | Drug Combinations | Escherichia coli - classification | Gram-Negative Bacteria - classification | Pharmaceutical research | Drug resistance in microorganisms | Research | Antibiosis | Drug interactions | Drugs | Larvae | Salmonella | Additives | Colistin | Clinical isolates | Infections | Drug resistance | Experiments | Proteins | E coli | Food additives | Bacteria | Pseudomonas aeruginosa | Drug dosages | Species | Public health | Food | Integrated approach | Bacterial infections | Antimicrobial agents | Gene expression | Antibiotics | Antimicrobial resistance | Vanillin | Drug additives | Life Sciences | Microbiology and Parasitology | Salmonella typhimurium/classification | Escherichia coli/drug effects | Anti-Bacterial Agents/pharmacology | Pseudomonas aeruginosa/drug effects | Pseudomonas aeruginosa/classification
Journal Article
Acta biomaterialia, ISSN 1742-7061, 2017, Volume 49, pp. 590 - 603
Journal Article
Nature (London), ISSN 1476-4687, 2018, Volume 555, Issue 7698, pp. 623 - 628
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 505, Issue 7484, pp. 559 - 563
Journal Article
by Meng, S and Zhang, L and Tang, Y and Tu, Q and Zheng, L and Yu, L and Murray, D and Cheng, J and Kim, S.H and Zhou, X and Chen, J
Journal of dental research, ISSN 1544-0591, 2014, Volume 93, Issue 7, pp. 657 - 662
...) inhibitor, JQ1, was proved to suppress oncogene transcription and inflammatory responses. The present study was aimed to investigate the effects of JQ1 on inflammatory response and bone destruction in experimental periodontitis... 
Epigenetics | Osteoclasts | BRD4 protein | Experimental animal models | Periodontitis | Anti-inflammatory agents | SELECTIVE-INHIBITION | HOMEOSTASIS | PROTEIN | CHROMATIN | experimental animal models | C-MYC | BRD4 INHIBITION | epigenetics | RESPONSES | DISRUPTION | DENTISTRY, ORAL SURGERY & MEDICINE | periodontitis | osteoclasts | BROMODOMAIN INHIBITION | anti-inflammatory agents | Interleukin-1beta - drug effects | Transcription Factor AP-1 - drug effects | Toll-Like Receptor 2 - antagonists & inhibitors | Alveolar Bone Loss - prevention & control | Cathepsin K - drug effects | Tartrate-Resistant Acid Phosphatase | Promoter Regions, Genetic - drug effects | Lipopolysaccharides - adverse effects | RANK Ligand - drug effects | Proto-Oncogene Proteins c-ets - drug effects | Cell Differentiation | Toll-Like Receptor 4 - antagonists & inhibitors | Acid Phosphatase - drug effects | Transcription Factors - therapeutic use | Cell Line | Proto-Oncogene Proteins c-fos - drug effects | Nuclear Proteins - therapeutic use | Periodontitis - prevention & control | NFATC Transcription Factors - drug effects | Animals | Tumor Necrosis Factor-alpha - drug effects | Isoenzymes - drug effects | Mice | Osteoclasts - drug effects | NF-kappa B - drug effects | Research Reports
Journal Article
PLoS genetics, ISSN 1553-7404, 2013, Volume 9, Issue 1, pp. e1003144 - e1003144
...]. Biofilm-associated antibiotic tolerance is mainly attributed to two distinct processes: persistence and drug indifference, which both characteristically disappear... 
HETEROGENEITY | CHROMOSOME | REPLICATION | PSEUDOMONAS-AERUGINOSA | ESCHERICHIA-COLI | SUSCEPTIBILITY | GENETICS & HEREDITY | GENE-EXPRESSION | RESISTANCE | BETA-LACTAM ANTIBIOTICS | INDUCTION | Biofilms - drug effects | Plankton - drug effects | Starvation | Drug Tolerance - genetics | Biofilms - growth & development | Amino Acids - genetics | Ofloxacin - pharmacology | Mutagenesis | Escherichia coli - genetics | Fluoroquinolones - pharmacology | SOS Response (Genetics) | DNA Transposable Elements - genetics | Plankton - genetics | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - drug effects | Escherichia coli - growth & development | Drug Resistance, Bacterial - genetics | Transposons | Antibiotics | Gene mutations | Physiological aspects | Genetic aspects | Dosage and administration | Research | Drug resistance | Health aspects | Biofilms | Microbiology | E coli | Bacteria | Mutation | Carbon | Index Medicus | Ofloxacin/pharmacology | DNA Transposable Elements/genetics | Bacterial/drug effects/genetics | Anti-Bacterial Agents/pharmacology | Plankton/drug effects/genetics | Escherichia coli/genetics/growth & development | Bacteriology | Fluoroquinolones/pharmacology | Life Sciences | Microbiology and Parasitology | Biofilms/drug effects/growth & development | Drug Tolerance/genetics | Amino Acids/genetics | Drug Resistance
Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64010
...) and inhibited the transmission of HIV captured by DC-SIGN(+)-cells to uninfected CD4(+) T cells (EC50:4.1 mu M). Time-of-drug... 
TARGET | HERPES-SIMPLEX-VIRUS | IN-VITRO | ENTRY | MULTIDISCIPLINARY SCIENCES | GRIFFITHSIN | INFECTION | SYNERGISTIC ACTIVITY | SEXUAL TRANSMISSION | TENOFOVIR | GEL | Anti-HIV Agents - pharmacology | Leukocytes, Mononuclear - metabolism | Lactobacillus - growth & development | Simplexvirus - physiology | Bacteriocins - chemistry | Epithelial Cells - drug effects | Giant Cells - drug effects | Humans | Virus Internalization - drug effects | HIV Envelope Protein gp120 - metabolism | Leukocytes, Mononuclear - virology | Lectins, C-Type - metabolism | HIV-1 - physiology | HIV Infections - pathology | HIV-1 - isolation & purification | Lactobacillus - drug effects | Protein Binding - drug effects | Female | Vagina - pathology | Simplexvirus - drug effects | Virus Replication - drug effects | Leukocytes, Mononuclear - drug effects | Receptors, CXCR5 - metabolism | HIV-1 - drug effects | HIV Infections - virology | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Nisin - metabolism | Cell Adhesion Molecules - metabolism | Receptors, CXCR4 - metabolism | Leukocytes, Mononuclear - pathology | Nisin - pharmacology | Epithelial Cells - microbiology | Bacteriocins - pharmacology | Drug Resistance, Viral - drug effects | Vagina - microbiology | Kinetics | CD4 Antigens - metabolism | Prevention | Technology application | Disease transmission | Peptides | T cells | HIV (Viruses) | Acyclovir | Antibacterial agents | Drugs | Sexually transmitted diseases--STD | Toxicity | Amino acids | Viruses | Lymphocytes T | Infections | Lantibiotics | Drug resistance | Proteins | Tenofovir | Synergistic effects | Saquinavir | CD69 antigen | Receptors | Microbicides | Enfuvirtide | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Antiviral activity | Lead | CD25 antigen | Bacteria | Inhibition | Pretreatment | Heparan sulfate | Medical research | Enzymes | Cytokines | Lactobacilli | Vagina | Envelope protein | Inflammation | Virology | CD4 antigen | DC-SIGN protein | Studies | Glycoprotein gp120 | Chemokines | STD | Sexually transmitted diseases | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
Journal Article
Journal Article