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1. Full Text Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose
by Garnett, James P and Baker, Emma H and Naik, Sonam and Lindsay, Jodi A and Knight, Gwenan M and Gill, Simren and Tregoning, John S and Baines, Deborah L
Thorax, ISSN 0040-6376, 09/2013, Volume 68, Issue 9, pp. 835 - 845
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Bronchoalveolar Lavage Fluid | Epithelial Cells - metabolism | Receptors, Leptin - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Epithelial Cells - drug effects | Pseudomonas aeruginosa - growth & development | Interleukin-1alpha - metabolism | Respiratory System - microbiology | Hyperglycemia - drug therapy | Bacterial Load - drug effects | Interleukin-6 - metabolism | Permeability - drug effects | Metformin - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Pseudomonas aeruginosa - drug effects | Blood Glucose - drug effects | Receptors, Leptin - deficiency | Animals | Hyperglycemia - blood | Respiratory System - metabolism | Chemokine CXCL9 - metabolism | Mice | Blood Glucose - metabolism | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Transforming Growth Factor beta - metabolism | Respiratory tract infections | Complications and side effects | Hyperglycemia | Causes of | Dosage and administration | Metformin | Drug therapy | Risk factors | Staphylococcus aureus | Index Medicus | Airway Epithelium | COPD Exacerbations | Respiratory Infection | 1506 | Bacterial Infection
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2. Long-term effects of inhaled corticosteroids on sputum bacterial and viral loads in COPD
by Contoli, Marco and Pauletti, Alessia and Rossi, Maria Rita and Spanevello, Antonio and Casolari, Paolo and Marcellini, Andrea and Forini, Giacomo and Gnesini, Giulia and Marku, Brunilda and Barnes, Neil and Rizzi, Andrea and Curradi, Giacomo and Caramori, Gaetano and Morelli, Paolo and Papi, Alberto
The European respiratory journal, ISSN 0903-1936, 10/2017, Volume 50, Issue 4, pp. 1700451 - 1700451
Life Sciences & Biomedicine | Respiratory System | Science & Technology | Sputum - microbiology | Glucocorticoids - administration & dosage | Bronchodilator Agents - administration & dosage | Pulmonary Disease, Chronic Obstructive - microbiology | Humans | Middle Aged | Male | Drug Monitoring - methods | Salmeterol Xinafoate - adverse effects | Bacterial Load - drug effects | Forced Expiratory Volume | Respiratory Tract Infections - microbiology | Long Term Adverse Effects - microbiology | Pulmonary Disease, Chronic Obstructive - blood | Bacterial Load - methods | Female | Eosinophils - pathology | Bronchodilator Agents - adverse effects | Fluticasone - adverse effects | Glucocorticoids - adverse effects | Pulmonary Disease, Chronic Obstructive - diagnosis | Administration, Inhalation | Treatment Outcome | Salmeterol Xinafoate - administration & dosage | Respiratory Tract Infections - diagnosis | Long Term Adverse Effects - diagnosis | Fluticasone - administration & dosage | Respiratory Function Tests | Viral Load - drug effects | Viral Load - methods | Pulmonary Disease, Chronic Obstructive - drug therapy | Respiratory therapy | Corticoids | Leukocytes (eosinophilic) | Propionic acid | Salmeterol | Microbiomes | Inflammation | Fluticasone | Inhalation | Respiratory tract | Sputum | Bacteria | Chronic obstructive pulmonary disease | Long-term effects
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3. Full Text Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations
by Singanayagam, Aran and Glanville, Nicholas and Girkin, Jason L and Ching, Yee Man and Marcellini, Andrea and Porter, James D and Toussaint, Marie and Walton, Ross P and Finney, Lydia J and Aniscenko, Julia and Zhu, Jie and Trujillo-Torralbo, Maria-Belen and Calderazzo, Maria Adelaide and Grainge, Chris and Loo, Su-Ling and Veerati, Punnam Chander and Pathinayake, Prabuddha S and Nichol, Kristy S and Reid, Andrew T and James, Phillip L and Solari, Roberto and Wark, Peter A. B and Knight, Darryl A and Moffatt, Miriam F and Cookson, William O and Edwards, Michael R and Mallia, Patrick and Bartlett, Nathan W and Johnston, Sebastian L
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2229 - 16
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung - microbiology | Fluticasone - pharmacology | Pulmonary Disease, Chronic Obstructive - microbiology | Humans | Mucus - virology | Pulmonary Disease, Chronic Obstructive - virology | Mucus - drug effects | Rhinovirus - physiology | Picornaviridae Infections - virology | Bacterial Load - drug effects | Lung - virology | Picornaviridae Infections - prevention & control | Fluticasone - immunology | Receptor, Interferon alpha-beta - genetics | Rhinovirus - immunology | Bacterial Infections - microbiology | Receptor, Interferon alpha-beta - metabolism | Rhinovirus - drug effects | Cell Line | Immunity, Innate - drug effects | Administration, Inhalation | Adrenal Cortex Hormones - pharmacology | Mice, Knockout | Mucus - microbiology | Bacterial Infections - prevention & control | Animals | Fluticasone - administration & dosage | Pulmonary Disease, Chronic Obstructive - prevention & control | Lung - drug effects | Adrenal Cortex Hormones - immunology | Adrenal Cortex Hormones - administration & dosage | Corticoids | Pneumonia | Immune response | Corticosteroids | Propionic acid | Lung diseases | Immune clearance | Health risks | Viruses | Mucus | Infections | Fluticasone | Disease control | Antiinfectives and antibacterials | Immunity | TLR3 protein | α-Interferon | Mucin | Obstructive lung disease | Toll-like receptors | Bacteria | Chronic obstructive pulmonary disease | Interferon | Index Medicus
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4. Full Text Effect of cadexomer iodine on the microbial load and diversity of chronic non-healing diabetic foot ulcers complicated by biofilm in vivo
by Malone, M and Johani, K and Jensen, S.O and Gosbell, I.B and Dickson, H.G and McLennan, S and Hu, H and Vickery, K
Journal of antimicrobial chemotherapy, ISSN 0305-7453, 07/2017, Volume 72, Issue 7, pp. 2093 - 2101
Pharmacology & Pharmacy | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Anti-Infective Agents, Local - therapeutic use | Humans | Middle Aged | Bacteria - drug effects | Male | Bacterial Load - drug effects | Iodophors - administration & dosage | Anti-Bacterial Agents - therapeutic use | Genetic Variation - drug effects | Aged, 80 and over | Female | Iodophors - therapeutic use | Wound Healing - drug effects | Biofilms - drug effects | Diabetic Foot - complications | Bacterial Load - genetics | In Situ Hybridization, Fluorescence | Diabetic Foot - microbiology | Bacteria - genetics | Pilot Projects | Anti-Infective Agents, Local - administration & dosage | Aged | High-Throughput Nucleotide Sequencing | Anti-Bacterial Agents - administration & dosage | Cohort Studies | Index Medicus | Original Research
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5. Full Text Antimicrobial Effects of Nisin, Essential Oil, and γ‐Irradiation Treatments against High Load of Salmonella typhimurium on Mini‐carrots
by Ndoti‐Nembe, Aude and Vu, Khanh Dang and Han, Jaejoon and Doucet, Nicolas and Lacroix, Monique
Journal of food science, ISSN 0022-1147, 07/2015, Volume 80, Issue 7, pp. M1544 - M1548
nisin | mountain savory essential oil | carvacrol | γ irradiation | Salmonella Typhimurium | Nisin | Carvacrol | Mountain savory essential oil | Bacterial Load - radiation effects | Food Contamination - prevention & control | Gamma Rays | Monoterpenes - pharmacology | Salmonella typhimurium - radiation effects | Nisin - pharmacology | Oils, Volatile - pharmacology | Anti-Bacterial Agents - pharmacology | Daucus carota - microbiology | Salmonella typhimurium - drug effects | Food Microbiology | Bacterial Load - drug effects | Index Medicus | Mountains | Salmonella | Microorganisms | Irradiation | Food processing | Coating | Antiinfectives and antibacterials
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6. Full Text Topical effects of frog “Rana ridibunda” skin secretions on wound healing and reduction of wound microbial load
by Mashreghi, Mohammad and Rezazade Bazaz, Mahere and Mahdavi Shahri, Nasser and Asoodeh, Ahmad and Mashreghi, Mansour and Behnam Rassouli, Morteza and Golmohammadzadeh, Shiva
Journal of ethnopharmacology, ISSN 0378-8741, 02/2013, Volume 145, Issue 3, pp. 793 - 797
Wound microbial load | Rana ridibunda | Wound healing | Amphibian skin secretions | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Neovascularization, Physiologic - drug effects | Complex Mixtures - therapeutic use | Skin - secretion | Male | Bacterial Load - drug effects | Skin - blood supply | Animals | Mice | Administration, Topical | Ointments | Wound Healing - drug effects | Skin - drug effects | Skin - pathology | Frogs | Skin | Universities and colleges | Amphibians | Analysis | Index Medicus
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7. Full Text Antibiotic Resistance in Human Chronic Periodontitis Microbiota
by Rams, Thomas E and Degener, John E and van Winkelhoff, Arie J
Journal of periodontology (1970), ISSN 0022-3492, 01/2014, Volume 85, Issue 1, pp. 160 - 169
AGGRESSIVE PERIODONTITIS | periodontal pocket | chronic periodontitis | SYSTEMIC AMOXICILLIN/METRONIDAZOLE | RANDOMIZED CLINICAL-TRIAL | SUSCEPTIBILITY | ANTIMICROBIAL AGENTS | ADULT PERIODONTITIS | ACTINOBACILLUS-ACTINOMYCETEMCOMITANS | REFRACTORY PERIODONTITIS | in vitro | Anti-infective agents | drug resistance | ADJUNCTIVE THERAPY | METRONIDAZOLE | Anti‐infective agents | Chronic periodontitis | Drug resistance | In vitro | Periodontal pocket | Life Sciences & Biomedicine | Dentistry, Oral Surgery & Medicine | Science & Technology | Enterococcus faecalis - drug effects | Prevotella intermedia - drug effects | Humans | Middle Aged | Drug Resistance, Bacterial | Male | Fusobacterium nucleatum - drug effects | Clindamycin - pharmacology | Dental Plaque - microbiology | Chronic Periodontitis - microbiology | Adult | Female | Periodontal Pocket - microbiology | Aggregatibacter actinomycetemcomitans - drug effects | Prevotella nigrescens - drug effects | Ciprofloxacin - pharmacology | Bacterial Load | Metronidazole - pharmacology | Amoxicillin - pharmacology | Doxycycline - pharmacology | Aged | Anti-Bacterial Agents - pharmacology | Candida - drug effects | Staphylococcus aureus - drug effects | Streptococcus constellatus - drug effects | Index Medicus | Dentistry
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8. Full Text Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity
by Murphy, Eileen F and Cotter, Paul D and Hogan, Aileen and O'Sullivan, Orla and Joyce, Andy and Fouhy, Fiona and Clarke, Siobhan F and Marques, Tatiana M and O'Toole, Paul W and Stanton, Catherine and Quigley, Eamonn M M and Daly, Charlie and Ross, Paul R and O'Doherty, Robert M and Shanahan, Fergus
Gut, ISSN 0017-5749, 02/2013, Volume 62, Issue 2, pp. 220 - 226
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Obesity | Biological and medical sciences | Metabolic diseases | Medical sciences | Intestines - drug effects | Probiotics - administration & dosage | Obesity - drug therapy | Bacteriocins - administration & dosage | Tumor Necrosis Factor-alpha - blood | Tumor Necrosis Factor-alpha - genetics | Bacteria - drug effects | Diet, High-Fat - adverse effects | Male | Obesity - microbiology | Inflammation - blood | Intestinal Mucosa - drug effects | Drug Delivery Systems | Vancomycin - pharmacology | Obesity - etiology | Weight Gain - drug effects | Gene Expression | Metagenome - drug effects | Vancomycin - administration & dosage | Mice, Inbred C57BL | Intestinal Mucosa - microbiology | Probiotics - pharmacology | Obesity - metabolism | Blood Glucose - drug effects | Animals | Intestines - microbiology | Tumor Necrosis Factor-alpha - drug effects | Triglycerides - blood | Bacteriocins - pharmacology | Anti-Bacterial Agents - pharmacology | Lactobacillus - physiology | Mice | Anti-Bacterial Agents - administration & dosage | Probiotics | Care and treatment | Microbiota (Symbiotic organisms) | Dosage and administration | Research | Vancomycin | Bacteriocins | Studies | Load | Diet | Rodents | Antimicrobial agents | Diabetes | Gene expression | Metabolic disorders | Index Medicus | Abridged Index Medicus
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9. Full Text Glycyrrhizin reduces HMGB1 and bacterial load in Pseudomonas aeruginosa keratitis
by Ekanayaka, Sandamali A and McClellan, Sharon A and Barrett, Ronald P and Kharotia, Shikhil and Hazlett, Linda D
Investigative ophthalmology & visual science, ISSN 0146-0404, 10/2016, Volume 57, Issue 13, pp. 5799 - 5809
Bacterial keratitis | Mice | Treatment | Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Pseudomonas aeruginosa - isolation & purification | Eye Infections, Bacterial - drug therapy | HMGB1 Protein - genetics | Bacterial Load - drug effects | HMGB1 Protein - metabolism | Anti-Inflammatory Agents - therapeutic use | Female | Cornea - pathology | Eye Infections, Bacterial - metabolism | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Cornea - microbiology | Keratitis - genetics | Enzyme-Linked Immunosorbent Assay | Eye Infections, Bacterial - genetics | Pseudomonas Infections - drug therapy | Mice, Inbred C57BL | RNA, Messenger - genetics | Gene Expression Regulation | Pseudomonas Infections - microbiology | Pseudomonas Infections - genetics | Glycyrrhizic Acid - therapeutic use | Animals | Keratitis - metabolism | Keratitis - drug therapy | Index Medicus | bacterial keratitis | treatment | mice | Immunology and Microbiology
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10. Full Text Effect on total microbial load and community composition with two vs six‐week topical Cadexomer Iodine for treating chronic biofilm infections in diabetic foot ulcers
by Malone, Matthew and Schwarzer, Saskia and Radzieta, Michael and Jeffries, Thomas and Walsh, Annie and Dickson, Hugh G and Micali, Grace and Jensen, Slade O
International wound journal, ISSN 1742-4801, 12/2019, Volume 16, Issue 6, pp. 1477 - 1486
diabetic foot ulcer | biofilms | Cadexomer Iodine | microbiome | Life Sciences & Biomedicine | Dermatology | Surgery | Science & Technology | Biofilms - drug effects | Microscopy, Electron, Scanning | Drug Administration Schedule | Humans | Middle Aged | Diabetic Foot - drug therapy | Male | Wound Healing | Bacteria - genetics | Bacterial Load - drug effects | DNA, Bacterial | Iodophors - administration & dosage | Bacteria - isolation & purification | Pilot Projects | Anti-Infective Agents, Local - administration & dosage | Female | High-Throughput Nucleotide Sequencing | Wound Infection - drug therapy | Administration, Topical | Cohort Studies | Index Medicus
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