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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2012, Volume 109, Issue 37, pp. 14779 - 14784
Total chemical synthesis was used to prepare the mirror image (D-protein) form of the angiogenic protein vascular endothelial growth factor (VEGF-A). Phage... 
Proteins | Bacteriophages | Molecules | Molecular structure | Ligands | Libraries | Chemical synthesis | Crystallography | Molecular chains | Crystal structure | CRYSTALLIZATION | SITE | DESIGN | D-PEPTIDE LIGANDS | CRYSTAL-STRUCTURE | ENANTIOMERS | VEGF | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN-BINDING DOMAIN | RECEPTOR | IMAGE PHAGE DISPLAY | Surface Plasmon Resonance | Amino Acid Sequence | Epitope Mapping | Enzyme-Linked Immunosorbent Assay | Stereoisomerism | Vascular Endothelial Growth Factor A - chemical synthesis | Open Reading Frames | Bacterial Proteins - genetics | Models, Molecular | Molecular Sequence Data | Crystallography, X-Ray | Vascular Endothelial Growth Factor A - metabolism | Chromatography, High Pressure Liquid | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor A - chemistry | Multiprotein Complexes - metabolism | Multiprotein Complexes - chemistry | Mass Spectrometry | Circular Dichroism | Antagonists (Biochemistry) | Physiological aspects | Research | Vascular endothelial growth factor | Index Medicus | SPECIFICITY | BASIC BIOLOGICAL SCIENCES | RESOLUTION | STOICHIOMETRY | CRYSTALLOGRAPHY | 60 APPLIED LIFE SCIENCES | PLASMONS | MIRRORS | MIXTURES | GROWTH FACTORS | SURFACE AREA | RESONANCE | AFFINITY | SYNTHESIS | SCREENS | PROTEINS | Biological Sciences | Physical Sciences | protein engineering | mirror image proteins | chemical protein synthesis | racemic X-ray crystallography
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 9, pp. 3773 - 3778
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 9/2003, Volume 162, Issue 6, pp. 1079 - 1088
Cell migration occurs through the protrusion of the actin-enriched lamella. Here, we investigated the effects of RNAi depletion of ∼90 proteins implicated in... 
Cell motility | Scars | Delta cells | Microfilaments | Neurons | Drosophila | Cell lines | Actins | Actin depolymerizing factors | Cells | Polymerization | Lamella | Cytokinesis | Actin | SCAR | RNA INTERFERENCE | MIGRATION | polymerization | lamella | cytokinesis | ARP2/3 COMPLEX | HOMOLOG | MOTILITY DRIVEN | CELL BIOLOGY | YEAST | actin | FILAMENTS | CYCLASE-ASSOCIATED PROTEIN | DYNAMICS | NUCLEATION | Pseudopodia - ultrastructure | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | Actins - metabolism | rac GTP-Binding Proteins - metabolism | Eukaryotic Cells - metabolism | Drosophila Proteins - metabolism | Cell Movement - physiology | Actins - genetics | Cell Cycle Proteins - antagonists & inhibitors | Actins - deficiency | RNA Interference | Profilins | Cell Cycle Proteins - genetics | Cytoskeletal Proteins - metabolism | Destrin | Drosophila Proteins - antagonists & inhibitors | Microfilament Proteins - genetics | Cell Line | Actin Cytoskeleton - metabolism | Microfilament Proteins - deficiency | Carrier Proteins - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Actin Depolymerizing Factors | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Actins - antagonists & inhibitors | Animals | Carrier Proteins - metabolism | Microfilament Proteins - antagonists & inhibitors | Caenorhabditis elegans Proteins - antagonists & inhibitors | Pseudopodia - metabolism | Drosophila Proteins - deficiency | Actin-Related Protein 2 | Eukaryotic Cells - cytology | Drosophila Proteins - genetics | Actin Cytoskeleton - ultrastructure | Caenorhabditis elegans Proteins - genetics | Drosophila melanogaster | Contractile Proteins | RNA | Listeria | Bacterial proteins | Cytology | Physiological aspects | Genetic aspects | Research | Cell migration | Proteins | Cytoskeleton | Cellular biology | Insects | Cell adhesion & migration | Index Medicus | actin; lamella; polymerization; SCAR; cytokinesis
Journal Article
Science, ISSN 0036-8075, 1/2009, Volume 323, Issue 5911, pp. 269 - 272
The Vibrio parahaemolyticus type III effector VopS is implicated in cell rounding and the collapse of the actin cytoskeleton by inhibiting Rho guanosine... 
Proteins | Phosphates | Enzymes | HeLa cells | Amino acids | Ions | Mass spectroscopy | Reports | Infections | Biochemistry | Post translational modification | ACTIVATION | PROTEIN | PARAHAEMOLYTICUS | MULTIDISCIPLINARY SCIENCES | III SECRETION SYSTEM | Phosphorylation | Threonine - chemistry | rho GTP-Binding Proteins - antagonists & inhibitors | Humans | Bacterial Proteins - chemistry | Molecular Sequence Data | rac GTP-Binding Proteins - metabolism | Vibrio parahaemolyticus - metabolism | cdc42 GTP-Binding Protein - metabolism | Threonine - metabolism | Recombinant Fusion Proteins - metabolism | rac GTP-Binding Proteins - antagonists & inhibitors | Cell Shape | cdc42 GTP-Binding Protein - antagonists & inhibitors | rho GTP-Binding Proteins - chemistry | Binding Sites | Protein Structure, Tertiary | Amino Acid Sequence | Signal Transduction | Adenosine Monophosphate - metabolism | Bacterial Proteins - genetics | Mutant Proteins - metabolism | Vibrio parahaemolyticus - pathogenicity | Amino Acid Motifs | Mutant Proteins - chemistry | rho GTP-Binding Proteins - metabolism | rac GTP-Binding Proteins - chemistry | Bacterial Proteins - metabolism | cdc42 GTP-Binding Protein - chemistry | Protein Processing, Post-Translational | HeLa Cells | Genetic aspects | Chemical properties | Guanosine triphosphatase | Vibrio | Signal transduction | Eukaryotes | Cellular biology | Molecular biology | Binding sites | Index Medicus
Journal Article
Science, ISSN 0036-8075, 10/2010, Volume 330, Issue 6001, pp. 219 - 222
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7460, pp. 102 - 106
The multidrug efflux transporter AcrB and its homologues are important in the multidrug resistance of Gram-negative pathogens(1,2). However, despite efforts to... 
GRAM-NEGATIVE BACTERIA | EFFLUX PUMP INHIBITORS | PSEUDOMONAS-AERUGINOSA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | RESISTANCE | TRANSPORTER ACRB | BINDING POCKET | SITE-DIRECTED MUTAGENESIS | STRATEGIES | Pyridines - chemistry | Protein Multimerization | Crystallography, X-Ray | Pyrimidinones - metabolism | Pyrimidines - chemistry | Pyrimidines - metabolism | Pyrimidinones - chemistry | Pseudomonas aeruginosa - metabolism | Anti-Bacterial Agents - chemistry | Membrane Transport Proteins - metabolism | Pyrimidinones - pharmacology | Escherichia coli Proteins - antagonists & inhibitors | Binding Sites | Bacterial Outer Membrane Proteins - antagonists & inhibitors | Multidrug Resistance-Associated Proteins - chemistry | Bacterial Outer Membrane Proteins - chemistry | Models, Molecular | Anti-Bacterial Agents - metabolism | Escherichia coli Proteins - metabolism | Multidrug Resistance-Associated Proteins - antagonists & inhibitors | Pyrimidines - pharmacology | Escherichia coli - chemistry | Rotation | Membrane Transport Proteins - chemistry | Pseudomonas aeruginosa - chemistry | Pyridines - metabolism | Bacterial Outer Membrane Proteins - metabolism | Hydrophobic and Hydrophilic Interactions | Anti-Bacterial Agents - pharmacology | Pyridines - pharmacology | Escherichia coli Proteins - chemistry | Multidrug Resistance-Associated Proteins - metabolism | Drug resistance in microorganisms | Pseudomonas aeruginosa | Research | Structure | Identification and classification | Crystals | Physiological aspects | Microbiological research | Biological transport | Proteins | Antibiotics | Bacteriology | Crystal structure | Index Medicus
Journal Article