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Cell, ISSN 0092-8674, 09/2016, Volume 167, Issue 1, pp. 233 - 247.e17
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 36, pp. 14944 - 14949
The bacterial pathogen Helicobacter pylori chronically infects the human gastric mucosa and is the leading risk factor for the development of gastric cancer.... 
Helicobacter pylori | Epithelial cells | DNA damage | DNA | Cell nucleus | Cell lines | Bacteria | Cultured cells | Infections | Mice | Chromosome breaks | DNA damage signaling | Gastric tumorigenesis | Genomic instability | CYTOLETHAL DISTENDING TOXIN | MULTIDISCIPLINARY SCIENCES | RISK | MISMATCH REPAIR | COLONIZATION | GENETIC INSTABILITY | EPITHELIAL-CELLS | chromosome breaks | GASTRIC-CANCER | INFLAMMATION | INFECTION | MICE | genomic instability | gastric tumorigenesis | Phosphorylation | Epithelial Cells - metabolism | Humans | Stomach Neoplasms - metabolism | Helicobacter Infections - complications | Stomach Neoplasms - pathology | Intracellular Signaling Peptides and Proteins - metabolism | Antigens, Bacterial - genetics | DNA Breaks, Double-Stranded | Helicobacter Infections - pathology | DNA-Binding Proteins - metabolism | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Helicobacter Infections - metabolism | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Stomach Neoplasms - genetics | Tumor Suppressor Proteins - metabolism | Chromosomal Proteins, Non-Histone - metabolism | Bacterial Proteins - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Genomic Islands | Epithelial Cells - pathology | Nuclear Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | DNA-Binding Proteins - genetics | Chromosomal Proteins, Non-Histone - genetics | Bacterial Adhesion | Stomach Neoplasms - microbiology | Animals | Histones - genetics | Helicobacter pylori - metabolism | Epithelial Cells - microbiology | Chromosome Aberrations | Cell Line, Tumor | Bacterial Proteins - metabolism | Trans-Activators - metabolism | Histones - metabolism | Tumor Suppressor p53-Binding Protein 1 | Antigens, Bacterial - metabolism | Carcinogens | Cocarcinogens | Physiological aspects | Genetic aspects | Research | Health aspects | Cells | Pathogens | Gram-negative bacteria | Rodents | Index Medicus | Adhesins | Histone H2A | Mesenchyme | Gastric mucosa | Carcinogenesis | Risk factors | Mammalian cells | Metaphase | genomics | Blood groups | Chromosomes | Gastric cancer | Gel electrophoresis | virulence factors | Infection | Cytotoxins | gamma -Glutamyltransferase | Molecular modelling | Microscopy | pathogenicity islands | Ataxia telangiectasia mutated protein | Chromosome aberrations | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 23, pp. 8452 - 8457
Journal Article
Nature Biotechnology, ISSN 1087-0156, 2014, Volume 32, Issue 6, pp. 569 - 576
  Monomeric CRISPR-Cas9 nucleases are widely used for targeted genome editing but can induce unwanted off-target mutations with high frequencies. Here we... 
Genetic research | Nucleases | Genetic aspects | Genetic engineering | Zinc finger proteins | Research | Biotechnology | Enzymes | Mutation | Genomics | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2010, Volume 207, Issue 8, pp. 1745 - 1755
Intracellular pathogens and endogenous danger signals in the cytosol engage NOD-like receptors (NLRs), which assemble inflammasome complexes to activate... 
MEDICINE, RESEARCH & EXPERIMENTAL | ASC | CANDIDA-ALBICANS | PROTEIN | MURAMYL DIPEPTIDE | ENTERICA SEROVAR TYPHIMURIUM | INFECTION | SECRETION | IMMUNOLOGY | CASPASE-1 ACTIVATION | IPAF | CELL-DEATH | Cytoplasmic Structures - genetics | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Salmonella Infections - immunology | Caspase 1 - metabolism | Blood - microbiology | Cytoplasmic Structures - drug effects | Interleukin-1beta - blood | Animal Structures - microbiology | Protein Transport - immunology | Cytoplasmic Structures - immunology | Immunity, Innate - physiology | Interleukin-1beta - metabolism | Flagellin - genetics | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Macrophages - microbiology | Interleukin-1 - metabolism | Interleukin-18 - blood | Salmonella typhimurium - genetics | Salmonella typhimurium - immunology | Membrane Proteins - genetics | Bacterial Proteins - genetics | Mice, Inbred Strains | Caspase Inhibitors | Protein Transport - genetics | Mice, Knockout | Protein Precursors - metabolism | Carrier Proteins - genetics | Macrophages - metabolism | Models, Immunological | Animals | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Cysteine Proteinase Inhibitors - pharmacology | Salmonella Infections - microbiology | Mice | Interleukin-18 - metabolism | Calcium-Binding Proteins - genetics | Cytoplasmic Structures - metabolism | Index Medicus
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2012, Volume 31, Issue 20, pp. 4005 - 4019
The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐transcriptional regulators known to date. Most previously... 
GcvB | Hfq | 3′ UTR | ABC transporter | DapZ | 30 UTR | 3 ' UTR | ENTERICA SEROVAR TYPHIMURIUM | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI GENOME | CELL BIOLOGY | BACTERIAL SMALL RNA | BINDING SMALL RNAS | SMALL NONCODING RNA | MESSENGER-RNA | PSEUDOMONAS-AERUGINOSA | SOLUBLE-RNA | DEPENDENT SMALL RNA | III SECRETION SYSTEM | Protein Biosynthesis | Immunoprecipitation | Lipoproteins - genetics | Salmonella typhimurium - growth & development | 3' Untranslated Regions - genetics | Molecular Sequence Data | Genes, Overlapping | RNA, Messenger - metabolism | Host Factor 1 Protein - metabolism | Salmonella typhimurium - metabolism | Virulence - genetics | Base Sequence | RNA, Bacterial - genetics | RNA, Small Untranslated - genetics | Transcription, Genetic | Nucleic Acid Conformation | RNA, Bacterial - metabolism | Protein Structure, Tertiary | Genes, Bacterial | Transcription Factors - physiology | Salmonella typhimurium - genetics | Salmonella typhimurium - pathogenicity | Carrier Proteins - biosynthesis | RNA, Messenger - genetics | Bacterial Proteins - genetics | Bacterial Proteins - physiology | Sequence Homology, Amino Acid | Carrier Proteins - genetics | Lipoproteins - biosynthesis | Gene Expression Regulation, Bacterial - genetics | Sequence Alignment | RNA Processing, Post-Transcriptional - genetics | Sequence Analysis, RNA | Bacterial Proteins - metabolism | Bacterial Proteins - biosynthesis | Proteins | Bacteria | Ribonucleic acid--RNA | Molecular biology | Genomics | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2011, Volume 333, Issue 6048, pp. 1445 - 1449
Bacterial chromosomes are confined in submicrometer-sized nucleoids. Chromosome organization is facilitated by nucleoid-associated proteins (NAPs), but the... 
Proteins | Molecules | DNA | Genes | Imaging | REPORTS | Cell lines | Genetic loci | Gene expression regulation | Genomes | Chromosomes | CELLS | STRUCTURING PROTEIN | CAULOBACTER-CRESCENTUS | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | GENE-EXPRESSION | OPTICAL RECONSTRUCTION MICROSCOPY | H-NS PROTEIN | BINDING | GENOME | Molecular Chaperones - metabolism | DNA, Bacterial - metabolism | Factor For Inversion Stimulation Protein - metabolism | Fimbriae Proteins - metabolism | Protein Multimerization | DNA, Bacterial - chemistry | Genetic Loci | Recombinant Fusion Proteins - metabolism | Escherichia coli K12 - ultrastructure | DNA-Binding Proteins - metabolism | Integration Host Factors - metabolism | Chromosomes, Bacterial - metabolism | Escherichia coli K12 - metabolism | Cell Division | Nucleic Acid Conformation | Binding Sites | Repressor Proteins - metabolism | Protein Structure, Tertiary | Genome, Bacterial | Repressor Proteins - chemistry | Operon | Repressor Proteins - genetics | Escherichia coli Proteins - metabolism | Chromosomes, Bacterial - ultrastructure | Fimbriae Proteins - genetics | Escherichia coli Proteins - genetics | Fimbriae Proteins - chemistry | Escherichia coli K12 - genetics | Escherichia coli Proteins - chemistry | Gene Expression Regulation, Bacterial | Cellular proteins | Research | Properties | Bacterial genetics | E coli | Microbiology | Bacterial proteins | Index Medicus
Journal Article