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The New England journal of medicine, ISSN 1533-4406, 01/2010, Volume 362, Issue 3, pp. 197 - 205
Journal Article
PloS one, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, pp. e0166477 - e0166477
Journal Article
ChemMedChem, ISSN 1860-7179, 04/2018, Volume 13, Issue 7, pp. 754 - 761
Cytotoxic necrotizing factor 1 (CNF1) is a toxin produced by pathogenic strains of Escherichia coli responsible for extra... 
inhibitors | CNF1 | screening | Rac1 | drug discovery | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Human Umbilical Vein Endothelial Cells | Immunoassay | Small Molecule Libraries - pharmacology | Humans | Monensin - pharmacology | Escherichia coli Proteins - metabolism | Drug Repositioning | Escherichia coli - chemistry | Lasalocid - pharmacology | Bacterial Toxins - adverse effects | Escherichia coli Proteins - adverse effects | Bacterial Toxins - antagonists & inhibitors | rac1 GTP-Binding Protein - immunology | Amodiaquine - pharmacology | Bacterial Toxins - metabolism | Diphtheria Toxin - adverse effects | Escherichia coli Proteins - antagonists & inhibitors | HeLa Cells | rac1 GTP-Binding Protein - chemistry | rac1 GTP-Binding Protein - metabolism | Bepridil - pharmacology | Drugs | Bacterial infections | Drug discovery | Drug approval | Gastrointestinal diseases | Escherichia coli | Biodegradation | Lasalocid | Monensin | Cytotoxic necrotizing factor | Fluorescence | Cytotoxicity | Rac1 protein | Inflammation | Infections | Diphtheria | Degradation | Inhibitors | E coli | Intestine | Cytotoxic necrotizing factor 1 | Proteasomes | Necrotizing factor 1 | Amodiaquine | Intoxication | Diphtheria toxin | Index Medicus | Bacterial Toxins/adverse effects | rac1 GTP-Binding Protein/immunology | Diphtheria Toxin/adverse effects | Lasalocid/pharmacology | Cellular Biology | Bacterial Toxins/antagonists & inhibitors | Life Sciences | Bepridil/pharmacology | Monensin/pharmacology | Small Molecule Libraries/pharmacology | Bacterial Toxins/metabolism | Subcellular Processes | rac1 GTP-Binding Protein/chemistry | Cell Behavior | Amodiaquine/pharmacology | Escherichia coli Proteins/antagonists & inhibitors | Bacteriology | Microbiology and Parasitology | Escherichia coli Proteins/adverse effects | Escherichia coli Proteins/metabolism | Escherichia coli/chemistry | rac1 GTP-Binding Protein/metabolism
Journal Article
Toxins, ISSN 2072-6651, 02/2017, Volume 9, Issue 2, p. 44
Journal Article
The Journal of infectious diseases, ISSN 0022-1899, 12/2015, Volume 212, Issue 11, pp. 1806 - 1815
BACKGROUND: Many enterotoxigenic Escherichia coli strains produce the heat-stable toxin, STa, which, by activation of the intestinal receptor-enzyme guanylyl cyclase (GC... 
Enzyme Inhibitors | Signal Transduction | Enterotoxins | Adenylyl Cyclases | Humans | Diarrhea | Cystic Fibrosis Transmembrane Conductance Regulator | Journal Article | Receptors, Guanylate Cyclase-Coupled | Young Adult | Animals | Escherichia coli Proteins | Jejunum | Bacterial Toxins | Models, Biological | Swine | Research Support, Non-U.S. Gov't | Piperidines | Receptors, Peptide | Adult | HeLa Cells | Enterotoxigenic Escherichia coli | Secretory diarrhea | CFTR | Guanylyl cyclase C | Enterotoxigenic E. coli (ETEC) | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Receptors, Guanylate Cyclase-Coupled - metabolism | Bacterial Toxins - antagonists & inhibitors | Jejunum - drug effects | Piperidines - pharmacology | Jejunum - cytology | Jejunum - secretion | Escherichia coli Proteins - antagonists & inhibitors | Cystic Fibrosis Transmembrane Conductance Regulator - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Escherichia coli Proteins - metabolism | Receptors, Peptide - antagonists & inhibitors | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Adenylyl Cyclases - metabolism | Receptors, Enterotoxin | Bacterial Toxins - metabolism | Signal Transduction - drug effects | Enterotoxins - antagonists & inhibitors | Enterotoxins - metabolism | Receptors, Guanylate Cyclase-Coupled - antagonists & inhibitors | Receptors, Peptide - metabolism | Care and treatment | Research | Guanylate cyclase | Escherichia coli | Index Medicus | Abridged Index Medicus
Journal Article
Antimicrobial agents and chemotherapy, ISSN 1098-6596, 02/2014, Volume 58, Issue 2, pp. 1108 - 1117
Journal Article