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humans (280) 280
science & technology (278) 278
baculoviral iap repeat-containing 3 protein (265) 265
life sciences & biomedicine (260) 260
ubiquitin-protein ligases (185) 185
inhibitor of apoptosis proteins - metabolism (171) 171
inhibitor of apoptosis proteins - genetics (159) 159
apoptosis (155) 155
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baculoviral iap repeat-containing 3 protein - metabolism (33) 33
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health aspects (29) 29
x-linked inhibitor of apoptosis protein - genetics (29) 29
caspases - metabolism (28) 28
cell proliferation - drug effects (27) 27
inhibitor of apoptosis proteins (26) 26
inhibitor of apoptosis proteins - biosynthesis (26) 26
reverse transcriptase polymerase chain reaction (26) 26
tumor necrosis factor-alpha - pharmacology (26) 26
analysis (25) 25
baculoviral iap repeat-containing 3 protein - genetics (25) 25
mutation (24) 24
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caspase 3 - metabolism (21) 21
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ciap2 (21) 21
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leukemia, lymphocytic, chronic, b-cell - genetics (20) 20
proto-oncogene proteins c-bcl-2 - metabolism (20) 20
rna interference (20) 20
tumor necrosis factor-alpha - metabolism (20) 20
gene expression profiling (19) 19
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rats (19) 19
tnf receptor-associated factor 2 - metabolism (19) 19
ubiquitination (19) 19
up-regulation (19) 19
immunohistochemistry (18) 18
intracellular signaling peptides and proteins - metabolism (18) 18
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multidisciplinary sciences (18) 18
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gene expression regulation, neoplastic - drug effects (17) 17
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receptor-interacting protein serine-threonine kinases - metabolism (17) 17
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ubiquitin (17) 17
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aged, 80 and over (15) 15
fundamental and applied biological sciences. psychology (15) 15
iap protein (15) 15
neoplasm proteins - genetics (15) 15
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Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 05/2012, Volume 55, Issue 9, pp. 4101 - 4113
Journal Article
Journal Article
Acta pharmacologica Sinica, ISSN 1671-4083, 11/2019, Volume 40, Issue 11, pp. 1466 - 1479
Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Reactive Oxygen Species - metabolism | Dipeptides - pharmacology | Humans | Autophagy - drug effects | Baculoviral IAP Repeat-Containing 3 Protein - chemistry | Antineoplastic Agents - metabolism | Signal Transduction - drug effects | Forkhead Transcription Factors - metabolism | Baculoviral IAP Repeat-Containing 3 Protein - metabolism | Benzimidazoles - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | X-Linked Inhibitor of Apoptosis Protein - chemistry | X-Linked Inhibitor of Apoptosis Protein - metabolism | Cell Line, Tumor | Protein Binding | Protein Domains | Benzimidazoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Docking Simulation | Dipeptides - metabolism | Cell proliferation | Biotechnology | Reactive oxygen species | Fluorescence | XIAP protein | Antagonists | Autophagy | Molecular docking | Anticancer properties | Time dependence | Cell activation | Catalase | Forkhead protein | FOXO3 protein | Translocation | Fluorescence polarization | IAP protein | Tumor cells | Caspase | Tumor cell lines | Tumor necrosis factor-α | Gene expression | BNIP3 protein | Nuclear transport | Domains | Gene silencing | Anisotropy | Regulatory mechanisms (biology) | Phagocytosis | Apoptosis | Index Medicus | carcinoma cells | IAP antagonists | autophagy | GDC-0152 | ROS | apoptosis | Foxo3 | catalase | WX20120108
Journal Article
by He, W and Wang, Q and Srinivasan, B and Xu, J and Padilla, M.T and Li, Z and Wang, X and Liu, Y and Gou, X and Shen, H.-M and Xing, C and Lin, Y
Oncogene, ISSN 0950-9232, 06/2014, Volume 33, Issue 23, pp. 3004 - 3013
apoptosis | autophagy | RIP3 | c-IAP | RIP1 | necroptosis | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | RNA, Small Interfering - genetics | Apoptosis - drug effects | Humans | Gene Expression Regulation, Neoplastic | Baculoviral IAP Repeat-Containing 3 Protein | Autophagy - drug effects | Gene Knockdown Techniques | MAP Kinase Kinase 4 - metabolism | MAP Kinase Signaling System - genetics | Chalcones - pharmacology | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Inhibitor of Apoptosis Proteins - metabolism | Membrane Proteins - metabolism | Beclin-1 | Nuclear Pore Complex Proteins - metabolism | RNA, Small Interfering - pharmacology | Imidazoles - pharmacology | Ubiquitin-Activating Enzymes - metabolism | Apoptosis Regulatory Proteins - metabolism | Ubiquitin-Protein Ligases | Autophagy-Related Protein 7 | Drug Resistance, Neoplasm - genetics | MAP Kinase Signaling System - drug effects | Membrane Proteins - antagonists & inhibitors | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cell Line, Tumor | MAP Kinase Kinase 4 - genetics | RNA-Binding Proteins - metabolism | Autophagy (Cytology) | Chemotherapy | Physiological aspects | Health aspects | c-Jun N-terminal kinases | Apoptosis | Cancer | Biodegradation | Autophagy | Index Medicus
Journal Article
European journal of immunology, ISSN 0014-2980, 09/2015, Volume 45, Issue 9, pp. 2672 - 2682
CD8+ memory T cell | Signal transduction | Ubiquitination | lymphocytic choriomeningitis virus | T‐cell memory | 4‐1BB | CD8 + memory T cell | 4-1BB | Lymphocytic choriomeningitis virus | T-cell memory | Life Sciences & Biomedicine | Immunology | Science & Technology | Lymphocytic choriomeningitis virus - immunology | CD8-Positive T-Lymphocytes - pathology | CD8-Positive T-Lymphocytes - transplantation | Inhibitor of Apoptosis Proteins - genetics | NF-kappa B - immunology | Cell Survival - genetics | Apoptosis - genetics | Baculoviral IAP Repeat-Containing 3 Protein | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | Adoptive Transfer | Lymphocytic Choriomeningitis - immunology | Ubiquitin-Protein Ligases - immunology | Female | Inhibitor of Apoptosis Proteins - metabolism | Immunologic Memory - genetics | Lymphocytic Choriomeningitis - genetics | Lymphocytic Choriomeningitis - virology | Signal Transduction | Lymphocytic Choriomeningitis - pathology | Antibodies, Monoclonal - pharmacology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Cells, Cultured | Gene Expression Regulation | Ubiquitin-Protein Ligases - metabolism | Mice, Transgenic | Cell Survival - immunology | Animals | Apoptosis - immunology | NF-kappa B - genetics | CD8-Positive T-Lymphocytes - virology | Lymphocyte Activation - drug effects | Tumor Necrosis Factor Receptor Superfamily, Member 9 - antagonists & inhibitors | Lymphocyte Count | Inhibitor of Apoptosis Proteins - immunology | Mice | Mutation | CD8-Positive T-Lymphocytes - immunology | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Cellular signal transduction | Memory (Computers) | T cells | Ligases | Lymphocytes | Rodents | T cell receptors | Index Medicus | LCMV | signal transduction | ubiquitination
Journal Article
Oncotarget, ISSN 1949-2553, 06/2016, Volume 7, Issue 23, pp. 33866 - 33886
IAP | Bone cancer | Smac | Osteosarcoma | RIP1 | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Osteosarcoma - drug therapy | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Cyclohexanes - pharmacology | Humans | Baculoviral IAP Repeat-Containing 3 Protein - antagonists & inhibitors | Ubiquitin-Protein Ligases - antagonists & inhibitors | Bone Neoplasms - pathology | Tumor Suppressor Protein p53 - genetics | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Bone Neoplasms - metabolism | Dose-Response Relationship, Drug | Bridged Bicyclo Compounds, Heterocyclic - toxicity | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Transfection | Triazoles - toxicity | Baculoviral IAP Repeat-Containing 3 Protein - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | HEK293 Cells | Bone Neoplasms - genetics | Inhibitor of Apoptosis Proteins - metabolism | Bone Neoplasms - drug therapy | Cyclohexanes - toxicity | Osteosarcoma - metabolism | Cell Survival - drug effects | Genetic Predisposition to Disease | Ubiquitin-Protein Ligases - metabolism | Retinoblastoma Protein - deficiency | Tumor Suppressor Protein p53 - deficiency | Mice, Knockout | Triazoles - pharmacology | Thiazoles - toxicity | Tumor Necrosis Factor-alpha - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Phenotype | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Pyrroles - toxicity | Retinoblastoma Protein - genetics | Cell Line, Tumor | Thiazoles - pharmacology | Osteosarcoma - genetics | Osteosarcoma - secondary | Index Medicus
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 215 - 227
Journal Article