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Journal of the American Society of Nephrology, ISSN 1046-6673, 02/2018, Volume 29, Issue 2, pp. 355 - 356
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 2014, Volume 29, Issue 1, pp. i19 - i24
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2015, Volume 88, pp. 93 - 100
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 05/2019, Volume 62, Issue 9, pp. 4683 - 4702
The KEAP1-NRF2-mediated cytoprotective response plays a key role in cellular homoeostasis. Insufficient NRF2 signaling during chronic oxidative stress may be... 
CHEMISTRY, MEDICINAL | NRF2 | MOLECULAR RECOGNITION | BARDOXOLONE METHYL | DLG MOTIFS | FRAGMENT | INDUCTION | STRESS | BINDING | DISCOVERY | LIGASE
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 07/2019, Volume 138, pp. 33 - 42
Transforming growth factor-β (TGF-β) is a potent pathogenic factor of renal injury through the upregulation of extracellular matrix (ECM) expression and... 
Bardoxolone methyl (BARD) | TGF-β | Glomerular mesangial cells | Renal fibrosis | Nfe2l2/Nrf2 | Smad7
Journal Article
FREE RADICAL BIOLOGY AND MEDICINE, ISSN 0891-5849, 07/2017, Volume 108, pp. 585 - 594
Journal Article
NATURE REVIEWS NEPHROLOGY, ISSN 1759-5061, 02/2015, Volume 11, Issue 2, pp. 68 - 69
In 2014, key studies in the field of diabetic nephropathy highlighted the importance of albuminuria as a predictor of cardiovascular risk and showed that the... 
MORTALITY | ALBUMINURIA | BARDOXOLONE METHYL | UROLOGY & NEPHROLOGY | TYPE-2
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 1901, Volume 17, Issue 3, pp. 794 - 805
Methyl 2-trifluoromethyl-3,11-dioxo-18b-olean-1,12dien- 3-oate (CF(3)DODA-Me) is derived synthetically from glycyrrhetinic acid, a major component of licorice,... 
ALVEOLAR | SPECIFICITY PROTEIN-1 | PAX3-FOXO1 | ONCOLOGY | PANCREATIC-CANCER CELL | BARDOXOLONE METHYL | GENES | UPDATE | BLADDER | IDENTIFICATION | EXPRESSION | CELL BIOLOGY
Journal Article
Kidney International, ISSN 0085-2538, 06/2013, Volume 83, Issue 6, pp. 1029 - 1041
Oxidative stress and inflammation are mediators in the development and progression of chronic kidney disease (CKD) and its complications, and they are... 
ESRD | cardiovascular disease | CKD progression | inflammation | antioxidant therapy | oxidative stress | Oxidative stress | Cardiovascular disease | Antioxidant therapy | Inflammation | CYTOPROTECTIVE GENES | GLUTATHIONE SYNTHESIS | CARBON-MONOXIDE | AORTIC COARCTATION | REVERSE CHOLESTEROL TRANSPORT | BARDOXOLONE METHYL | CYCLOPENTENONE PROSTAGLANDINS | DENSITY-LIPOPROTEIN | UROLOGY & NEPHROLOGY | HEME OXYGENASE-1 | RENAL INJURY | Humans | Oleanolic Acid - analogs & derivatives | Kidney - immunology | NF-E2-Related Factor 2 - agonists | Renal Insufficiency, Chronic - drug therapy | Renal Insufficiency, Chronic - metabolism | Inflammation - metabolism | Kidney - metabolism | Time Factors | Inflammation - drug therapy | Renal Insufficiency, Chronic - diagnosis | Acute Kidney Injury - immunology | Inflammation - diagnosis | Oleanolic Acid - therapeutic use | Kidney Failure, Chronic - immunology | Kidney - drug effects | Renal Insufficiency, Chronic - immunology | Acute Kidney Injury - drug therapy | Kidney Failure, Chronic - drug therapy | Anti-Infective Agents - therapeutic use | Treatment Outcome | Inflammation - immunology | Disease Progression | Kidney Failure, Chronic - metabolism | Antioxidants - therapeutic use | Animals | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Acute Kidney Injury - metabolism | bardoxolone methyl
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 2018, Volume 42, Issue 20, pp. 16782 - 16794
A practical and novel approach has been developed for the synthesis of oleanolic acid based chromene analogues. Different ,-unsaturated carbonyl and chromene... 
POTENTIAL ANTICANCER AGENTS | URSOLIC ACID | APOPTOSIS | TRITERPENOIDS | BARDOXOLONE METHYL | INFLAMMATION | BIOLOGICAL EVALUATION | INHIBITORS | DERIVATIVES | CANCER | CHEMISTRY, MULTIDISCIPLINARY
Journal Article