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Nature cell biology, ISSN 1476-4679, 2010, Volume 12, Issue 3, pp. 299 - 305
For most types of cancers, the cell at the origin of tumour initiation is still unknown. Here, we used mouse genetics to identify cells at the origin of basal... 
POPULATION | STEM-CELLS | SONIC HEDGEHOG | EPIDERMIS | HAIR FOLLICLE BULGE | KERATINOCYTES | CANCER | EXPRESSION | HUMAN HOMOLOG | MOUSE SKIN | CELL BIOLOGY | Epithelial Cells - metabolism | Cadherins - metabolism | Receptors, G-Protein-Coupled - metabolism | Skin - metabolism | Cell Count | Ear, External - pathology | Integrin beta4 - metabolism | Tail - pathology | Hair Follicle - pathology | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Kruppel-Like Transcription Factors - metabolism | Smoothened Receptor | Neoplastic Stem Cells - pathology | Cell Differentiation | Patched Receptors | Skin - pathology | Keratin-10 - metabolism | Epidermis - metabolism | Epidermis - pathology | RNA, Untranslated | Bacterial Proteins - genetics | Receptors, Cell Surface - metabolism | Epithelial Cells - pathology | Genes, Reporter - genetics | Mice, Transgenic | Carcinoma, Basal Cell - pathology | Mice, Inbred Strains | Clone Cells - metabolism | Keratin-14 - genetics | Carcinoma, Basal Cell - metabolism | Keratin-15 - metabolism | Keratin-19 - genetics | Proteins - genetics | Cell Lineage | Animals | Clone Cells - pathology | Proteins - metabolism | Models, Biological | Hair Follicle - metabolism | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Receptors, G-Protein-Coupled - genetics | Integrases - genetics | Keratin-15 - genetics | Luminescent Proteins - metabolism | Basal cell carcinoma | Stem cells | Genetic aspects | Cellular signal transduction | Research | Health aspects | Risk factors
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2008, Volume 40, Issue 2, pp. 170 - 180
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2015, Volume 290, Issue 17, pp. 10840 - 10849
Journal Article
Clinical & Experimental Ophthalmology, ISSN 1442-6404, 01/2006, Volume 34, Issue 1, pp. 64 - 73
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 2012, Volume 53, Issue 10, pp. 1857 - 1867
Huntington’s disease (HD) is a CAG repeat disorder affecting the HD gene, which encodes for huntingtin (Htt) and is characterized by prominent cell death in... 
Striatal cells | Oxidative stress | Reactive oxygen species | Huntingtin | Huntington disease | MRP1 | PROTEIN | INCREASED OXIDATIVE DAMAGE | BASAL GANGLIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTANT HUNTINGTIN | GENE | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | MITOCHONDRIAL DYSFUNCTION | STRESS | BRAIN | Reactive Oxygen Species - metabolism | Oxidative Stress | Glutathione - metabolism | Glutathione Reductase - metabolism | Huntington Disease - pathology | Caspase 3 - metabolism | RNA, Messenger - metabolism | Corpus Striatum - cytology | Corpus Striatum - metabolism | Glutathione - pharmacology | Biological Transport | Multidrug Resistance-Associated Proteins - genetics | Neostriatum - metabolism | Glutamate-Cysteine Ligase - metabolism | Glutathione Synthase - metabolism | Nuclear Proteins - genetics | Glutathione Peroxidase - metabolism | Glutathione - analogs & derivatives | Oxidation-Reduction | RNA, Messenger - genetics | Cells, Cultured | Glutathione Transferase - metabolism | Nuclear Proteins - metabolism | gamma-Glutamyltransferase - metabolism | Huntington Disease - metabolism | Nerve Tissue Proteins - genetics | Gene Knock-In Techniques | Nerve Tissue Proteins - metabolism | Huntingtin Protein | Animals | Huntington Disease - genetics | Mice | Mutation | Multidrug Resistance-Associated Proteins - metabolism | Antioxidants | Drug resistance in microorganisms | Messenger RNA | Thiols | Huntington's chorea | Ligases | Glutathione transferase | Cell death | Analysis | Peroxidase | Cells
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 8, p. e43962
The function of small intestinal monoacylglycerol lipase (MGL) is unknown. Its expression in this tissue is surprising because one of the primary functions of... 
DIACYLGLYCEROL ACYLTRANSFERASE | ENZYME | METABOLISM | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | MONOGLYCERIDE LIPASE | MICE | PLASMA LEPTIN | TRIGLYCERIDE SYNTHESIS | DIETARY-FAT INTAKE | RAT ADIPOSE-TISSUE | Endocannabinoids - metabolism | Basal Metabolism - physiology | Mice, Transgenic | Glycerides - metabolism | Polyunsaturated Alkamides - metabolism | Agouti-Related Protein - metabolism | Obesity - genetics | Monoacylglycerol Lipases - genetics | Eating - physiology | Obesity - metabolism | Triglycerides - metabolism | Brain - metabolism | Neuropeptide Y - metabolism | Pro-Opiomelanocortin - metabolism | Monoacylglycerol Lipases - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Arachidonic Acids - metabolism | Animals | Adiposity - physiology | Appetite - physiology | Mice | Intestine, Small - metabolism | Energy Metabolism - physiology | Obesity | Physiological aspects | Genetic aspects | Research | Lipase | Endocannabinoids | Risk factors | Metabolic rate | Adipose tissue | Body fat | Mucosa | Body weight | Lipids | Genomes | Small intestine | Proteins | Cannabinoids | Energy | Transgenic animals | Rodents | Lean body mass | Enzymes | Phenotypes | Transgenic mice | Glycerol | Energy expenditure | Triglycerides | Metabolism | Gene expression | Fatty acids | Body weight gain | Energy balance | Overexpression | Diet | Body mass | Food intake | Insulin resistance | Diabetes
Journal Article
Journal Article
The European journal of neuroscience, ISSN 1460-9568, 2008, Volume 27, Issue 3, pp. 654 - 670
Journal Article
Journal Article
Journal of cellular physiology, ISSN 0021-9541, 2010, Volume 225, Issue 3, pp. 682 - 691