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Journal of Experimental Medicine, ISSN 0022-1007, 05/2007, Volume 204, Issue 5, pp. 1119 - 1130
Journal Article
Immunity, ISSN 1074-7613, 06/2014, Volume 40, Issue 6, pp. 896 - 909
Animal host defense against infection requires the expression of defense genes at the right place and the right time. Understanding such tight control of host... 
LIFE-SPAN | IMMUNE-RESPONSE | PATHOGEN INTERACTIONS | CAENORHABDITIS-ELEGANS | DROSOPHILA-MELANOGASTER | AUTOPHAGY GENES | REGULATES AUTOPHAGY | STAPHYLOCOCCUS-AUREUS | IMMUNOLOGY | C. ELEGANS | LYSOSOMAL BIOGENESIS | Pseudomonas aeruginosa - immunology | Caenorhabditis elegans - microbiology | Transcriptional Activation - genetics | Caenorhabditis elegans Proteins - immunology | Salmonella Infections - immunology | Transcriptional Activation - immunology | Autophagy - immunology | Signal Transduction - immunology | RNA Interference | Autophagy - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - immunology | Macrophages - immunology | Enterococcus faecalis - immunology | Basic Helix-Loop-Helix Transcription Factors - genetics | Staphylococcal Infections - immunology | Immunity, Innate | Caenorhabditis elegans - immunology | Pseudomonas Infections - immunology | Animals | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Salmonella enterica - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Staphylococcus aureus - immunology | Mice | RNA, Small Interfering | Caenorhabditis elegans Proteins - genetics | Genetic aspects | Genetic transcription | Analysis | Gastrointestinal diseases | Genes | Genomics | Signal transduction | Transcription factors | Nematodes | Staphylococcus infections | Kinases | Mammals | Gene expression | Experiments | Autophagy | Chemokines | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 563 - 573
Mice lacking junctional adhesion molecule A (JAM-A, encoded by ) exhibit enhanced intestinal epithelial permeability, bacterial translocation, and elevated... 
GROWTH-FACTOR-BETA | INFLAMMATORY-BOWEL-DISEASE | IMMUNOGLOBULIN-A | IN-VIVO | REGULATORY T-CELLS | JUNCTIONAL-ADHESION-MOLECULE | DEFICIENT MICE | E-CADHERIN | IMMUNOLOGY | ORAL ANTIGEN | EXPRESSION | Dextran Sulfate | Cell Adhesion Molecules - genetics | Intestinal Mucosa - metabolism | Colitis - genetics | Immunoglobulin A - genetics | Male | Homeodomain Proteins - immunology | Intestines - metabolism | Cell Adhesion Molecules - immunology | Intestines - immunology | Adaptive Immunity - genetics | CD4-Positive T-Lymphocytes - immunology | Epithelium - immunology | Flow Cytometry | Intestinal Mucosa - immunology | Colitis - chemically induced | Female | Adaptive Immunity - immunology | Colitis - immunology | Transforming Growth Factor beta - immunology | Gene Expression | Bacterial Translocation - genetics | Epithelium - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Bacterial Translocation - immunology | Intestinal Mucosa - microbiology | Permeability | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Cell Surface - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Intestines - microbiology | Transforming Growth Factor beta - genetics | Immunoglobulin A - immunology | Mice | Transforming Growth Factor beta - metabolism | Receptors, Cell Surface - genetics | Disease susceptibility | Colitis | T cells | Transforming growth factors | Immunoglobulin A | Inflammatory bowel disease | Studies | Medical research | Nutrition research | Disease | Antibiotics | Lymphocytes | Rodents | Small intestine | Immune system | Cell adhesion & migration | Index Medicus | Medical and Health Sciences | Homeodomain Proteins/genetics/immunology | Medicin och hälsovetenskap | Cell Surface/genetics/immunology | Colitis/chemically induced/genetics/immunology | CD4-Positive T-Lymphocytes/immunology/metabolism | Bacterial Translocation/genetics/immunology | Receptors | Immunoglobulin A/genetics/immunology | Transforming Growth Factor beta/genetics/immunology/metabolism | Intestinal Mucosa/immunology/metabolism/microbiology | Adaptive Immunity/genetics/immunology | Basic Medicine | Intestines/immunology/metabolism/microbiology | Cell and Molecular Biology | Inbred C57BL | Knockout | Cell Adhesion Molecules/genetics/immunology | Epithelium/immunology/metabolism | Medicinska och farmaceutiska grundvetenskaper | Cell- och molekylärbiologi
Journal Article
Mucosal Immunology, ISSN 1933-0219, 03/2016, Volume 9, Issue 2, pp. 352 - 363
In inflammatory bowel diseases, a breakdown in host microbial interactions accompanies sustained activation of immune cells in the gut. Functional studies... 
CD103(+)CD11B(+) DENDRITIC CELLS | TISSUE MACROPHAGES | ANTIGEN-PRESENTING CELLS | LY6C(HI) MONOCYTES | MEDIATED COLITIS | IMMUNOLOGY | DEPENDENT MECHANISM | IMMUNE DEFENSE | T-CELLS | AUTOIMMUNE ENCEPHALOMYELITIS | BOWEL-DISEASE | Colitis - genetics | Dendritic Cells - immunology | Basic-Leucine Zipper Transcription Factors - immunology | Colon - immunology | Gene Expression Profiling | Monocytes - immunology | Antigens, CD - genetics | CD11c Antigen - immunology | Helicobacter Infections - pathology | Interleukin-23 - genetics | Receptors, IgG - genetics | CD11c Antigen - genetics | Intestinal Mucosa - immunology | Integrin alpha Chains - immunology | Monocytes - pathology | Macrophages - microbiology | Monocytes - microbiology | Macrophages - pathology | Signal Transduction | Colon - pathology | Repressor Proteins - genetics | Epithelial Cells - pathology | Mice, Transgenic | Helicobacter Infections - immunology | Intestinal Mucosa - microbiology | Receptors, IgG - immunology | Helicobacter Infections - genetics | Interleukin-23 - immunology | Colitis - microbiology | Histocompatibility Antigens Class II - immunology | Epithelial Cells - microbiology | Repressor Proteins - immunology | Dendritic Cells - microbiology | Mice | Receptors, Immunologic - genetics | Chronic Disease | Helicobacter Infections - microbiology | Intestinal Mucosa - pathology | Antigens, CD - immunology | Lectins, C-Type - immunology | Dendritic Cells - pathology | Colitis - pathology | Lectins, C-Type - genetics | Receptors, Immunologic - immunology | Colitis - immunology | Macrophages - immunology | Helicobacter hepaticus - immunology | Gene Expression Regulation | Basic-Leucine Zipper Transcription Factors - genetics | Animals | Epithelial Cells - immunology | Histocompatibility Antigens Class II - genetics | Integrin alpha Chains - genetics | Index Medicus
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 20, pp. 2457 - 2464
Highlights • We developed and tested a new oral ETEC vaccine in mice, alone and with an adjuvant. • The vaccine contains E. coli overexpressing CFA/I, CS3, CS5... 
Allergy and Immunology | Vaccine | Mucosal immunity | Immune responses | ETEC | dmLT | Colonization factors | DmLT | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNITY | DIARRHEA | PREVENTION | IMMUNOLOGY | VIBRIO-CHOLERAE | CELL CHOLERA VACCINE | TRAVELERS | CONSTRUCTION | ENTEROTOXIGENIC ESCHERICHIA-COLI | INTRANASAL IMMUNIZATION | ANTIBODY-RESPONSES | Immunity, Mucosal - immunology | Adjuvants, Immunologic - administration & dosage | Immunoglobulin G - blood | Escherichia coli Infections - prevention & control | Antigens, Bacterial - immunology | Antigens, Bacterial - genetics | Intestines - immunology | Enterotoxins - immunology | Escherichia coli Proteins - administration & dosage | Immunoglobulin G - immunology | Cholera Toxin - immunology | Bacterial Toxins - genetics | Female | Escherichia coli Proteins - immunology | Immunoglobulin G - analysis | Mutant Proteins - immunology | Fimbriae Proteins - immunology | Cholera Toxin - administration & dosage | Antibody Formation - immunology | Vaccines, Inactivated - genetics | Administration, Oral | Bacterial Toxins - immunology | Escherichia coli Infections - microbiology | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Mutant Proteins - administration & dosage | Enterotoxins - administration & dosage | Vaccines, Inactivated - adverse effects | Enterotoxins - genetics | Vaccines, Inactivated - immunology | Animals | Escherichia coli Vaccines - adverse effects | Fimbriae Proteins - genetics | Vaccines, Inactivated - administration & dosage | Cholera Toxin - genetics | Immunoglobulin A - immunology | Escherichia coli Proteins - genetics | Immunoglobulin A - blood | Bacterial Toxins - administration & dosage | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Mice | Mice, Inbred BALB C | Escherichia coli Vaccines - immunology | Immunoglobulin A - analysis | Antigens | Safety and security measures | Analysis | Escherichia coli | Bacteria | Vaccines | Contamination | Proteins | Studies | Immunology | E coli | Rodents | Index Medicus | Basic Medicine | Medicinska grundvetenskaper
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2016, Volume 17, Issue 6, pp. 626 - 635
Innate lymphoid cells (ILCs) are critical mediators of mucosal immunity, and group 1 ILCs (ILC1 cells) and group 3 ILCs (ILC3 cells) have been shown to be... 
BET | PATHOGENESIS | NATURAL-KILLER-CELLS | CYTOKINES | PROGENITOR | ROR-GAMMA-T | TRANSCRIPTION FACTOR GATA3 | INFECTION | DIFFERENTIATION | IMMUNOLOGY | TYPE-1 | GATA3 Transcription Factor - genetics | Smoking - adverse effects | Humans | Middle Aged | Male | Th2 Cells - immunology | Cell Plasticity - immunology | Th1 Cells - immunology | Lymphocytes - immunology | Inflammation Mediators - metabolism | Female | Influenza A virus - immunology | Cell Differentiation | GATA3 Transcription Factor - metabolism | Cytokines - metabolism | Staphylococcal Infections - immunology | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Immunity, Innate | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Mice, Knockout | Phenotype | Animals | Haemophilus influenzae - immunology | Staphylococcus aureus - immunology | Aged | Mice | Haemophilus Infections - immunology | Pulmonary Disease, Chronic Obstructive - immunology | Lung - immunology | Orthomyxoviridae Infections - immunology | Physiological aspects | Phenotypic plasticity | Development and progression | Lung diseases, Obstructive | Lymphoid tissue | Health aspects | Index Medicus | Basic Medicine | Immunologi inom det medicinska området | Medical and Health Sciences | Medicin och hälsovetenskap | Immunology in the medical area | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7377, pp. 336 - 343
Variable regions 1 and 2 (V1/V2) of human immunodeficiency virus-1 (HIV-1) gp120 envelope glycoprotein are critical for viral evasion of antibody... 
SYSTEM | POTENT NEUTRALIZATION | DEXTRAN SULFATE | EPITOPE | MULTIDISCIPLINARY SCIENCES | IMMUNODEFICIENCY-VIRUS TYPE-1 | ENVELOPE GLYCOPROTEIN | RECEPTOR | BINDING | T-CELLS | SOFTWARE | AIDS Vaccines - immunology | Glycopeptides - chemistry | Molecular Sequence Data | Antibody Affinity - immunology | Crystallography, X-Ray | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antibodies, Neutralizing - immunology | Glycopeptides - immunology | Antibody Specificity - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | Protein Structure, Quaternary | Conserved Sequence | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Binding Sites, Antibody - immunology | Models, Molecular | Glycosylation | Polysaccharides - immunology | HIV Antibodies - chemistry | AIDS Vaccines - chemistry | Amino Acid Motifs | HIV-1 - immunology | Immune Evasion | Hydrogen Bonding | Antigen-Antibody Complex - chemistry | Antibodies, Neutralizing - chemistry | Epitopes - chemistry | Antigen-Antibody Complex - immunology | Viral envelopes | Genetic aspects | Research | HIV (Viruses) | Structure | Binding sites (Biochemistry) | Proteins | Crystals | Vaccines | Index Medicus | ANTIBODIES | AIDS VIRUS | BASIC BIOLOGICAL SCIENCES | AFFINITY | BIOLOGY | GLYCOPROTEINS | VULNERABILITY | ANTIGENS | IMMUNOLOGY | 60 APPLIED LIFE SCIENCES
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2015, Volume 16, Issue 8, pp. 838 - 849
Interferon-gamma (IFN-gamma) primes macrophages for enhanced microbial killing and inflammatory activation by Toll-like receptors (TLRs), but little is known... 
BACTERIAL PATHOGENS | DENDRITIC CELLS | PATHWAY | IMMUNE-RESPONSES | KINASE | IMMUNOLOGY | POLARIZATION | EXPRESSION | TRYPTOPHAN CATABOLISM | MTOR | I INTERFERON | Toll-Like Receptor 2 - genetics | TOR Serine-Threonine Kinases - metabolism | Homeodomain Proteins - metabolism | Humans | Protein Biosynthesis - immunology | Eukaryotic Initiation Factor-4E - metabolism | Multiprotein Complexes - genetics | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | Base Sequence | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Macrophage Activation - immunology | Signal Transduction - genetics | Toll-Like Receptor 2 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - metabolism | Signal Transduction - drug effects | Toll-Like Receptor 2 - immunology | Protein Biosynthesis - drug effects | MicroRNAs - genetics | Multiprotein Complexes - immunology | RNA, Messenger - immunology | Transcription Factor HES-1 | Macrophage Activation - genetics | Intracellular Signaling Peptides and Proteins - immunology | Homeodomain Proteins - immunology | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | Eukaryotic Initiation Factor-4E - immunology | Protein Biosynthesis - genetics | Eukaryotic Initiation Factor-4E - genetics | Macrophages - immunology | RNA, Messenger - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Homeodomain Proteins - genetics | TOR Serine-Threonine Kinases - immunology | Interferon-gamma - immunology | Basic Helix-Loop-Helix Transcription Factors - immunology | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Macrophage Activation - drug effects | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Index Medicus
Journal Article