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Statistics in Medicine, ISSN 0277-6715, 11/2018, Volume 37, Issue 25, pp. 3557 - 3572
Journal Article
Surgical Oncology Clinics of North America, ISSN 1055-3207, 10/2017, Volume 26, Issue 4, pp. 791 - 797
Journal Article
Journal Article
CANCER JOURNAL, ISSN 1528-9117, 07/2019, Volume 25, Issue 4, pp. 245 - 253
Journal Article
TRIALS, ISSN 1745-6215, 09/2019, Volume 20, Issue 1, pp. 1 - 10
Background Master protocols, classified as basket trials, umbrella trials, and platform trials, are novel designs that investigate multiple hypotheses through... 
TARGETED THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | Platform trials | Multi-arm | Basket trials | PHASE-II | OPEN-LABEL | CELECOXIB | PLUS HORMONE-THERAPY | DISEASE | STAMPEDE | MULTISTAGE | Master protocols | Umbrella trials | multi-stage design | ADAPTIVE RANDOMIZATION | MULTIARM | Literacy programs | Multi-arm, multi-stage design
Journal Article
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 10/2016, Volume 11, Issue 1, pp. 1 - 5
Journal Article
Statistics in Medicine, ISSN 0277-6715, 12/2019, Volume 38, Issue 29, pp. 5470 - 5485
As biomarker information from early‐phase trials can be unreliable due to high variability, it is logical to take a prospective two‐stage approach when... 
O'Brien‐Fleming boundary | basket design | biomarker adaptive enrichment | population selection | ascending design
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 04/2019, Volume 25, Issue 7, pp. 2049 - 2057
The 2018 Accelerating Anticancer Agent Development ( AAADV) Workshop assembled a panel of experts for an in-depth discussion session to present "Challenges... 
CELL LUNG-CANCER | BASKET TRIALS | PEMBROLIZUMAB | BIOMARKER | ONCOLOGY | THERAPIES | ACCELERATED APPROVAL | NIVOLUMAB | TUMORS | DOCETAXEL
Journal Article
Molecular Oncology, ISSN 1574-7891, 03/2019, Volume 13, Issue 3, pp. 549 - 557
Journal Article
Cancer Treatment Reviews, ISSN 0305-7372, 02/2019, Volume 73, pp. 20 - 30
•Precision medicine stands to substantially improve oncology.•Developing such approaches necessitates a new breed of clinical trial designs.•So far, 30 basket... 
Biomarker | Precision medicine | Basket trial | Umbrella trial | SURROGATE END-POINTS | MULTICENTER | RANDOMIZED-TRIALS | UMBRELLA TRIALS | CHALLENGES | BREAST-CANCER | PUBLICATIONS | MASTER PROTOCOLS | BASKET TRIALS | THERAPY | ONCOLOGY | Clinical trials | Medical colleges
Journal Article
Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 30, pp. 21383 - 21395
Investigating targeted therapies can be challenging due to diverse tumor mutations and slow patient accrual for clinical studies. The Signature Program is a... 
Mutations | Clinical trial design | Basket trial | Tissue agnostic | Signature
Journal Article
CANCER JOURNAL, ISSN 1528-9117, 07/2019, Volume 25, Issue 4, pp. 282 - 286
Precision medicine incorporates information regarding tumor biology involved in patients' carcinogenesis and individualized treatment of patients using drugs... 
SURVIVAL | genomic profiling | targeted therapy | ADVANCED CANCER | Basket trials | BRAF | personalized medicine | LUNG-CANCER | INHIBITION | ONCOLOGY | precision medicine | MUTATIONS | PROGRAM
Journal Article