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1. Full Text A pump‐free microfluidic 3D perfusion platform for the efficient differentiation of human hepatocyte‐like cells
by Ong, Louis Jun Ye and Chong, Lor Huai and Jin, Lin and Singh, Pawan Kumar and Lee, Poh Seng and Yu, Hanry and Ananthanarayanan, Abhishek and Leo, Hwa Liang and Toh, Yi‐Chin
Biotechnology and bioengineering, ISSN 0006-3592, 10/2017, Volume 114, Issue 10, pp. 2360 - 2370
human stem cells | pump‐free | microfluidics | hepatocytes | 3D perfusion culture | pump-free | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Organ Culture Techniques - methods | Tissue Engineering - methods | Cell Culture Techniques - instrumentation | Perfusion - instrumentation | Humans | Cell Proliferation - physiology | Cells, Cultured | Lab-On-A-Chip Devices | Stem Cells - cytology | Cell Culture Techniques - methods | Equipment Design | Tissue Engineering - instrumentation | Hepatocytes - cytology | Stem Cells - physiology | Organ Culture Techniques - instrumentation | Batch Cell Culture Techniques - instrumentation | Batch Cell Culture Techniques - methods | Cell Differentiation - physiology | Equipment Failure Analysis | Hepatocytes - physiology | Liver | Microfluidics | Stem cells | Cell culture | Animal models | Computer simulation | Maturation | Flow rates | Spheroids | Hepatocytes | Simulation | Perfusion | Rodents | Hydrostatic pressure | Computer applications | Cells (biology) | Particle image velocimetry | Reservoirs | Pressure head | Velocity measurement | Differentiation | In vitro methods and tests | Viability | Index Medicus
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2. Full Text Direct 3D bioprinting of perfusable vascular constructs using a blend bioink
by Jia, Weitao and Gungor-Ozkerim, P. Selcan and Zhang, Yu Shrike and Yue, Kan and Zhu, Kai and Liu, Wanjun and Pi, Qingment and Byambaa, Batzaya and Dokmeci, Mehmet Remzi and Shin, Su Ryon and Khademhosseini, Ali
Biomaterials, ISSN 0142-9612, 2016, Volume 106, pp. 58 - 68
Advanced Basic Science | Dentistry | 3D Bioprinting | Bioink | Endothelial cells | Perfusable hollow tube | Mesenchymal stem cells | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Organ Culture Techniques - methods | Blood Vessels - growth & development | Perfusion - instrumentation | Humans | Cells, Cultured | Ink | Equipment Design | Bioartificial Organs | Blood Vessels - cytology | Tissue Scaffolds | Neovascularization, Physiologic - physiology | Tissue Engineering - instrumentation | Printing, Three-Dimensional - instrumentation | Bioreactors | Endothelial Cells - cytology | Organ Culture Techniques - instrumentation | Batch Cell Culture Techniques - instrumentation | Endothelial Cells - physiology | Transplantation of organs, tissues, etc | Ethylene glycol | Biological products | Biomimetics | Tissue engineering | Stem cells | Index Medicus | Bioengineering | Construction | Blends | Three dimensional printing | Construction engineering | Extrusion | Biomaterials
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3. Full Text Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission – The SPHEROIDS project
by Pietsch, Jessica and Gass, Samuel and Nebuloni, Stefano and Echegoyen, David and Riwaldt, Stefan and Baake, Christin and Bauer, Johann and Corydon, Thomas J and Egli, Marcel and Infanger, Manfred and Grimm, Daniela
Biomaterials, ISSN 0142-9612, 2017, Volume 124, pp. 126 - 156
Advanced Basic Science | Dentistry | Science validation test | International space station | Automated experiment container | Experiment sequence test | Endothelial cells | Biocompatibility test | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Cell Culture Techniques - instrumentation | Humans | Cell Proliferation - physiology | Cells, Cultured | Weightlessness | Robotics - instrumentation | Equipment Design | Tissue Engineering - instrumentation | Printing, Three-Dimensional - instrumentation | Endothelial Cells - cytology | Space Flight - instrumentation | Batch Cell Culture Techniques - instrumentation | Endothelial Cells - physiology | Equipment Failure Analysis | Ketones | Analysis | Space stations | Endothelium | Index Medicus
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4. Full Text Process development of human multipotent stromal cell microcarrier culture using an automated high‐throughput microbioreactor
by Rafiq, Qasim A and Hanga, Mariana P and Heathman, Thomas R. J and Coopman, Karen and Nienow, Alvin W and Williams, David J and Hewitt, Christopher J
Biotechnology and bioengineering, ISSN 0006-3592, 10/2017, Volume 114, Issue 10, pp. 2253 - 2266
bioprocessing | microcarrier | scale down | microbioreactor | cell therapy | human mesenchymal multipotent stromal cell | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cell Culture Techniques - instrumentation | Humans | Cell Proliferation - physiology | Cells, Cultured | Robotics - instrumentation | Cell Culture Techniques - methods | Equipment Design | Culture Media, Serum-Free - metabolism | Microfluidics - instrumentation | Mesenchymal Stromal Cells - cytology | Pilot Projects | Bioreactors | Miniaturization | Batch Cell Culture Techniques - instrumentation | Batch Cell Culture Techniques - methods | Microfluidics - methods | Equipment Failure Analysis | Mesenchymal Stromal Cells - physiology | Cell culture | Automation | Agitation | Mesenchyme | High-throughput screening | Coefficient of variation | Cell density | Serum-free medium | Reproducibility | Lag phase | Stem cells | Cell adhesion | Process parameters | Index Medicus
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5. Full Text Advantages and challenges of microfluidic cell culture in polydimethylsiloxane devices
by Halldorsson, Skarphedinn and Lucumi, Edinson and Gómez-Sjöberg, Rafael and Fleming, Ronan M.T
Biosensors & bioelectronics, ISSN 0956-5663, 01/2015, Volume 63, pp. 218 - 231
Cell culture | Polydimethylsiloxane | Microfluidic | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Life Sciences & Biomedicine | Electrochemistry | Science & Technology - Other Topics | Biophysics | Chemistry, Analytical | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Biological and medical sciences | Animals | Biocompatible Materials - chemistry | Humans | Cells, Cultured | Microfluidic Analytical Techniques - instrumentation | Dimethylpolysiloxanes - chemistry | Batch Cell Culture Techniques - instrumentation | Equipment Design | Equipment Failure Analysis | Analysis | Cells | Dimethylpolysiloxane | Index Medicus | Polystyrene resins | Cellular | Silicone resins | Biosensors | Devices | Microfluidics | Culture
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6. Full Text Coaxial nozzle-assisted 3D bioprinting with built-in microchannels for nutrients delivery
by Gao, Qing and He, Yong and Fu, Jian-zhong and Liu, An and Ma, Liang
Biomaterials, ISSN 0142-9612, 2015, Volume 61, pp. 203 - 215
Advanced Basic Science | Dentistry | Cell viability | 3D bioprinting | Coaxial nozzle | Filament fusion | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Flow Cytometry - instrumentation | Cell Line | Fibroblasts - physiology | Cell Proliferation - physiology | Lab-On-A-Chip Devices | Equipment Design | Tissue Engineering - instrumentation | Culture Media - pharmacokinetics | Animals | Printing, Three-Dimensional - instrumentation | Flow Injection Analysis - instrumentation | Fibroblasts - cytology | Mice | Culture Media - chemistry | Batch Cell Culture Techniques - instrumentation | Cell Survival - physiology | Equipment Failure Analysis | Crosslinked polymers | Index Medicus | Bioengineering | Platforms | Three dimensional printing | Filaments | Crosslinking | Viability | Three dimensional | Microchannels
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7. Full Text Comparison of spectroscopy technologies for improved monitoring of cell culture processes in miniature bioreactors
by Rowland‐Jones, Ruth C and van den Berg, Frans and Racher, Andrew J and Martin, Elaine B and Jaques, Colin
Biotechnology progress, ISSN 8756-7938, 03/2017, Volume 33, Issue 2, pp. 337 - 346
process analytical technology (PAT) | near‐infrared spectroscopy | Raman spectroscopy | 2D‐fluorescence | design of experiments | near-infrared spectroscopy | 2D-fluorescence | Food Science & Technology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Reproducibility of Results | Cell Culture Techniques - instrumentation | Cricetulus | Gene Expression Profiling - methods | Cell Culture Techniques - methods | Gene Expression Profiling - instrumentation | Spectrum Analysis - instrumentation | Animals | CHO Cells - metabolism | Bioreactors | Models, Biological | Spectrum Analysis - methods | Computer Simulation | Sensitivity and Specificity | Monitoring, Physiologic - methods | Monitoring, Physiologic - instrumentation | Miniaturization | Batch Cell Culture Techniques - instrumentation | Batch Cell Culture Techniques - methods | Lactates | Usage | Metabolites | Fluorescence | Information management | Comparative analysis | Index Medicus | Sensing, Identification, and Control of Cell‐based Processes | Special Section
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8. Full Text Fed‐batch and perfusion culture processes: Economic, environmental, and operational feasibility under uncertainty
by Pollock, James and Ho, Sa V and Farid, Suzanne S
Biotechnology and bioengineering, ISSN 0006-3592, 01/2013, Volume 110, Issue 1, pp. 206 - 219
fed‐batch | perfusion | stochastic discrete‐event simulation | MySQL database | cell culture | biopharmaceutical manufacture | antibody production | process economics | Cell culture | Biopharmaceutical manufacture | Antibody production | Perfusion | Process economics | Fed-batch | Stochastic discrete-event simulation | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cells, Cultured | Biotechnology - methods | Stochastic Processes | Bioreactors | Models, Biological | Computer Simulation | Biotechnology - economics | Antibodies, Monoclonal - metabolism | Batch Cell Culture Techniques - instrumentation | Batch Cell Culture Techniques - methods | Monte Carlo Method | Batch Cell Culture Techniques - economics | Biotechnology - instrumentation | Monoclonal antibodies | Monte Carlo method | Sustainable development | Analysis | Decision making | Risk assessment | Monte Carlo simulation | Index Medicus
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