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Nature (London), ISSN 1476-4687, 2010, Volume 463, Issue 7282, pp. 769 - 774
.... Addictive drugs increase the levels of dopamine and also trigger long-lasting synaptic adaptations in the mesolimbic reward system that ultimately may induce the pathological behaviour... 
CELLS | EVOKED SYNAPTIC PLASTICITY | ACID | RAT | ABUSE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GABA(B) RECEPTORS | MIDBRAIN DOPAMINERGIC-NEURONS | MODULATION | VENTRAL TEGMENTAL AREA | gamma-Aminobutyric Acid - metabolism | Midazolam - administration & dosage | Neuronal Plasticity - drug effects | Substrate Specificity | Electric Conductivity | Ventral Tegmental Area - cytology | Receptors, GABA-A - deficiency | Midazolam - adverse effects | Neurons - metabolism | Behavior, Addictive - physiopathology | Neurons - drug effects | Action Potentials - drug effects | Dopamine - metabolism | Receptors, AMPA - metabolism | Ventral Tegmental Area - drug effects | Behavior, Addictive - pathology | Benzodiazepines - pharmacology | Morphine - pharmacology | Administration, Oral | Mice, Inbred C57BL | Interneurons - drug effects | Inhibitory Postsynaptic Potentials - physiology | Organ Specificity | Animals | Interneurons - metabolism | Behavior, Addictive - chemically induced | Models, Biological | Receptors, GABA-A - genetics | Ventral Tegmental Area - metabolism | Benzodiazepines - administration & dosage | Benzodiazepines - adverse effects | Glutamic Acid - metabolism | Mice | Receptors, GABA-A - metabolism | In Vitro Techniques | Midazolam - pharmacology | Inhibitory Postsynaptic Potentials - drug effects | Usage | Receptors | Neurons | Analysis | GABA | Research | Ventral tegmental area | Benzodiazepines | Proteins | Drugs | Addictions | Polyamines | Addictive behaviors
Journal Article
Journal Article
Journal Article
Addiction (Abingdon, England), ISSN 0965-2140, 2012, Volume 107, Issue 1, pp. 27 - 38
Journal Article
Annual review of pharmacology and toxicology, ISSN 1545-4304, 2009, Volume 49, Issue 1, pp. 57 - 71
Journal Article
Neuron, ISSN 0896-6273, 2008, Volume 59, Issue 3, pp. 486 - 496
.... To test the role of NMDAR-dependent plasticity in addictive behavior, we genetically inactivated functional NMDAR signaling exclusively in DA neurons (KO mice... 
SYSNEURO | HUMDISEASE | AMPA RECEPTORS | SENSITIZATION | IN-VIVO | MIDBRAIN DOPAMINE | GENE-EXPRESSION | SYNAPTIC PLASTICITY | NEUROSCIENCES | GABAERGIC NEURONS | VENTRAL TEGMENTAL AREA | COCAINE-INDUCED POTENTIATION | NUCLEUS-ACCUMBENS | Tyrosine 3-Monooxygenase - metabolism | Locomotion - genetics | Membrane Potentials - radiation effects | Ventral Tegmental Area - cytology | Psychomotor Performance - physiology | N-Methylaspartate - pharmacology | Behavior, Animal | Dopamine - deficiency | Exploratory Behavior - physiology | Neuronal Plasticity - physiology | Exploratory Behavior - drug effects | Neurons - physiology | Behavior, Addictive - physiopathology | Dopamine - metabolism | Locomotion - drug effects | Membrane Potentials - drug effects | Behavior, Addictive - genetics | Mice, Transgenic | Membrane Potentials - physiology | Dopamine Plasma Membrane Transport Proteins - genetics | Nerve Tissue Proteins - genetics | Receptors, N-Methyl-D-Aspartate - physiology | Carrier Proteins - genetics | Cocaine - pharmacology | Patch-Clamp Techniques | Animals | Behavior, Addictive - chemically induced | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Luminescent Proteins - genetics | Mice | In Vitro Techniques | Luminescent Proteins - metabolism | Methyl aspartate | Neurons | Dopamine | Electrodes | Neurosciences | Rodents | Addictive behaviors | Cocaine | Behavior | Addictions | Acquisitions & mergers
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