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Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9744, pp. 875 - 885
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 08/2014, Volume 83, pp. 274 - 283
Trypanosomes from the “brucei” complex are pathogenic parasites endemic in sub-Saharan Africa and causative agents of severe diseases in humans and livestock.... 
Nagana | Chalcones | Cinnamides | Trypanosoma brucei brucei | Paullones | Human trypanosomiasis | CHEMISTRY, MEDICINAL | VALIDATION | BRUCEI | HUMAN SERUM | SIDE-CHAINS | TRYPANOTHIONE SYNTHETASE | BLOOD-STREAM | AFFINITY-CHROMATOGRAPHY | DRUG TARGET | IMMOBILIZED AXIN | Cell Line | Humans | Trypanocidal Agents - toxicity | Trypanocidal Agents - chemistry | Structure-Activity Relationship | Benzazepines - pharmacology | Benzazepines - chemical synthesis | Trypanosoma brucei brucei - drug effects | Trypanosoma brucei brucei - physiology | Trypanosomiasis, African - parasitology | Animals | Trypanocidal Agents - pharmacology | Drug Design | Trypanocidal Agents - chemical synthesis | Macrophages - drug effects | Cell Proliferation - drug effects | Mice | Benzazepines - toxicity | Benzazepines - chemistry | Substitution reactions | Antiparasitic agents | Livestock | Trypanocidal Agents/chemistry | Trypanocidal Agents/chemical synthesis | Trypanosoma brucei brucei/drug effects | Trypanocidal Agents/pharmacology | Biochemistry, Molecular Biology | Benzazepines/pharmacology | Trypanosomiasis, African/parasitology | Life Sciences | Benzazepines/toxicity | Macrophages/drug effects | Benzazepines/chemistry | Trypanosoma brucei brucei/physiology | Trypanocidal Agents/toxicity | Cell Proliferation/drug effects | Benzazepines/chemical synthesis
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 12, pp. 1091 - 1099
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9744, pp. 886 - 894
Summary Background Raised resting heart rate is a marker of cardiovascular risk. We postulated that heart rate is also a risk factor for cardiovascular events... 
Internal Medicine | RATE REDUCTION | HUMAN MYOCARDIUM | MEDICINE, GENERAL & INTERNAL | SYSTOLIC DYSFUNCTION BEAUTIFUL | CARDIOVASCULAR-DISEASE | DOUBLE-BLIND | ATHEROSCLEROSIS | CORONARY-ARTERY-DISEASE | BETA-BLOCKER | IVABRADINE | LEFT-VENTRICULAR FUNCTION | Benzazepines - adverse effects | Humans | Middle Aged | Heart Failure - physiopathology | Male | Sinoatrial Node - drug effects | Heart Rate - drug effects | Electrocardiography | Adult | Female | Heart Failure - mortality | Severity of Illness Index | Heart Failure - complications | Cardiovascular Agents - administration & dosage | Double-Blind Method | Risk Factors | Kaplan-Meier Estimate | Treatment Outcome | Heart Failure - drug therapy | Cardiovascular Agents - therapeutic use | Benzazepines - therapeutic use | Aged | Benzazepines - administration & dosage | Cardiovascular Agents - adverse effects | Chronic Disease | Heart failure | Prevention | Heart beat | Dosage and administration | Drug therapy | Health aspects | Risk factors | Cardiovascular agents | Studies | Heart rate | Cardiovascular disease | Mortality | Cardiovascular diseases | use | Sinoatrial Node/drug effects | Heart Failure/complications/drug therapy/mortality/physiopathology | Kardiologi | Cardiac and Cardiovascular Systems | Benzazepines/administration & dosage/adverse effects/therapeutic use | Heart Rate/drug effects | Cardiovascular Agents/administration & dosage/adverse effects/therapeutic | Kaplan-Meiers Estimate
Journal Article
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 05/2016, Volume 2016, Issue 5, p. CD006103
Background Nicotine receptor partial agonists may help people to stop smoking by a combination of maintaining moderate levels of dopamine to counteract... 
Smoking [drug therapy] | Varenicline | Humans | RANDOMIZED CONTROLLED-TRIAL | Quinolizines [therapeutic use] | PSYCHIATRIC ADVERSE EVENTS | TOBACCO-DEPENDENCE TREATMENT | Quinoxalines [therapeutic use] | MEDICINE, GENERAL & INTERNAL | Bupropion [therapeutic use] | Nicotine [adverse effects; antagonists & inhibitors] | REPLACEMENT THERAPY | SUSTAINED-RELEASE BUPROPION | Smoking Cessation [methods] | Counseling [methods] | VARENICLINE TREATMENT | METHADONE-MAINTAINED SMOKERS | Randomized Controlled Trials as Topic | Azepines [therapeutic use] | DOUBLE-BLIND PLACEBO | Alkaloids [therapeutic use] | Nicotinic Agonists [adverse effects; therapeutic use] | Azocines [therapeutic use] | LONG-TERM SAFETY | Benzazepines [therapeutic use] | PLACEBO-CONTROLLED TRIAL | Substance Withdrawal Syndrome [prevention & control] | Heterocyclic Compounds with 4 or More Rings [therapeutic use] | Quinolizines - therapeutic use | Azepines - adverse effects | Azocines - therapeutic use | Azocines - adverse effects | Substance Withdrawal Syndrome - prevention & control | Alkaloids - adverse effects | Benzazepines - adverse effects | Smoking - drug therapy | Heterocyclic Compounds, 4 or More Rings - adverse effects | Nicotinic Agonists - therapeutic use | Nicotine - antagonists & inhibitors | Smoking Cessation - methods | Azepines - therapeutic use | Nicotine - adverse effects | Nicotinic Agonists - adverse effects | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Benzazepines - therapeutic use | Counseling - methods | Alkaloids - therapeutic use | Quinolizines - adverse effects | Varenicline - therapeutic use | Bupropion - therapeutic use
Journal Article