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Journal Article
Environment International, ISSN 0160-4120, 2011, Volume 37, Issue 1, pp. 226 - 247
A broad spectrum of organic chemicals is essential to modern society. Once discharged from industrial, domestic and urban sources into the urban wastewater... 
Polychlorinated alkanes | Polychlorinated naphthalenes | Perfluorochemicals | Phthalate acid esters | Hormones | Sewage sludge | Biosolids | Triclocarban | Bisphenol A | Polybrominated diphenyl ethers | Quaternary ammonium compounds | Antibiotics | Organotins | Triclosan | Synthetics musks | Polydimethylsiloxanes | Land application | Pharmaceuticals | Benzothiazoles | Steroids | WASTE-WATER TREATMENT | ENDOCRINE DISRUPTING COMPOUNDS | SOLID-PHASE EXTRACTION | SEWAGE-TREATMENT PLANTS | ENVIRONMENTAL RISK-ASSESSMENT | PHTHALIC-ACID ESTERS | POLYCHLORINATED N-ALKANES | TANDEM MASS-SPECTROMETRY | ENVIRONMENTAL SCIENCES | FLUOROQUINOLONE ANTIBACTERIAL AGENTS | Naphthalenes - chemistry | Sewage - chemistry | Environmental Monitoring | Organotin Compounds - chemistry | Benzhydryl Compounds | Naphthalenes - analysis | Dimethylpolysiloxanes - analysis | Waste Disposal, Fluid | Halogenated Diphenyl Ethers - chemistry | Halogenated Diphenyl Ethers - analysis | Soil Pollutants - analysis | Organic Chemicals - analysis | Phenols - analysis | Environmental Pollution - statistics & numerical data | Internationality | Organotin Compounds - analysis | Pharmaceutical Preparations - chemistry | Phenols - chemistry | Agriculture | Dimethylpolysiloxanes - chemistry | Recycling | Pharmaceutical Preparations - analysis | Human | Priorities | Toxicity | Contaminants | Assessments | Sludge | Monitoring | Waste water | Farming | Index Medicus
Journal Article
Nature Biotechnology, ISSN 1087-0156, 01/2010, Volume 28, Issue 1, pp. 63 - 70
Phosphodiesterase 4 (PDE4), the primary cAMP-hydrolyzing enzyme in cells, is a promising drug target for a wide range of conditions. Here we present seven... 
CAMP-SPECIFIC PHOSPHODIESTERASE | PHOSPHORYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN-KINASE | GENE COMPOSER | SUNCUS-MURINUS | AMP-SPECIFIC PHOSPHODIESTERASE | INHIBITORS | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE | ROLIPRAM BINDING | ANTIDEPRESSANT DRUGS | Phosphodiesterase Inhibitors - therapeutic use | Phosphodiesterase Inhibitors - adverse effects | Humans | Molecular Sequence Data | Crystallography, X-Ray | Structure-Activity Relationship | Benzhydryl Compounds - chemistry | Benzhydryl Compounds - adverse effects | Phenylurea Compounds - adverse effects | Phenylurea Compounds - chemistry | Drug Design | Phosphodiesterase 4 Inhibitors | Behavior, Animal - drug effects | Biological Assay | Phosphodiesterase Inhibitors - chemistry | Benzhydryl Compounds - therapeutic use | Cyclic Nucleotide Phosphodiesterases, Type 4 - chemistry | Disease Models, Animal | Allosteric Regulation - drug effects | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Catalytic Domain | Models, Molecular | Phenylurea Compounds - therapeutic use | Phosphodiesterase Inhibitors - pharmacology | Vomiting - drug therapy | Cognition - drug effects | Animals | Benzhydryl Compounds - pharmacology | Mice | Phenylurea Compounds - pharmacology | Kinetics | Care and treatment | Schizophrenia | Physiological aspects | Genetic aspects | Cellular signal transduction | Cyclic adenylic acid | Research | Phosphodiesterases | Enzymes | Biotechnology | Cellular biology | Molecular biology | Cognitive ability | Crystal structure | Index Medicus
Journal Article
Journal Article