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Biochemistry (Easton), ISSN 0006-2960, 05/2017, Volume 56, Issue 17, pp. 2294 - 2303
The toxicities of azole pollutants that have widespread agricultural and industrial uses are either poorly understood or unknown, particularly with respect to... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Benzimidazoles - toxicity | Triazoles - chemistry | Imidazoles - chemistry | Fungicides, Industrial - toxicity | Isoenzymes - chemistry | Environmental Pollutants - metabolism | Benzimidazoles - chemistry | Recombinant Fusion Proteins - metabolism | Fungicides, Industrial - metabolism | Peroxidases - antagonists & inhibitors | Triazoles - toxicity | Isoenzymes - metabolism | Peroxidases - chemistry | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Peroxidases - metabolism | Imidazoles - toxicity | Environmental Pollutants - toxicity | Pesticides - metabolism | Polychaeta - enzymology | Imidazoles - metabolism | Recombinant Proteins - metabolism | Catalytic Domain | Indazoles - chemistry | Enzyme Inhibitors - metabolism | Computational Biology | Hemoglobins - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Indazoles - metabolism | Recombinant Fusion Proteins - chemistry | Fungicides, Industrial - chemistry | Amino Acid Motifs | Triazoles - metabolism | Hemoglobins - antagonists & inhibitors | Hemoglobins - chemistry | Animals | Environmental Pollutants - chemistry | Hydrogen Bonding | Pesticides - toxicity | Benzimidazoles - metabolism | Indazoles - toxicity | Hydrophobic and Hydrophilic Interactions | Pesticides - chemistry | Ligands | Kinetics | Isoenzymes - antagonists & inhibitors | Azoles (Class of compounds) | Computational chemistry | Usage | Chemical properties | X-ray spectroscopy | Research | Index Medicus
Journal Article
Journal Article
Chemical Society reviews, ISSN 1460-4744, 2013, Volume 42, Issue 19, pp. 7747 - 7762
Journal Article
Current medicinal chemistry, ISSN 0929-8673, 2018, Volume 25, Issue 34, pp. 4432 - 4456
SIRT1 is a nicotinamide adenosine dinucleotide (NAD(+))-dependent deacetylase, which removes acetyl groups from many target proteins, such as histone proteins,... 
NAD | cardioprotection | STACs | activators | SIRT1 | deacetylation | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Sirtuin 1 - metabolism | Cardiotonic Agents - metabolism | Cardiovascular Diseases - drug therapy | Humans | Resveratrol - metabolism | Ginsenosides - metabolism | Resveratrol - therapeutic use | Benzimidazoles - chemistry | Cardiovascular Diseases - pathology | Ginsenosides - therapeutic use | Lignans - therapeutic use | Cardiotonic Agents - therapeutic use | Resveratrol - chemistry | Heterocyclic Compounds, 4 or More Rings - therapeutic use | Sirtuin 1 - chemistry | Polycyclic Compounds - metabolism | Benzimidazoles - therapeutic use | Polycyclic Compounds - chemistry | Lignans - chemistry | Heterocyclic Compounds, 4 or More Rings - chemistry | Cyclooctanes - metabolism | Cardiotonic Agents - chemistry | Lignans - metabolism | Cyclooctanes - therapeutic use | Benzimidazoles - metabolism | Heterocyclic Compounds, 4 or More Rings - metabolism | Cyclooctanes - chemistry | Polycyclic Compounds - therapeutic use | Ginsenosides - chemistry | Cardiovascular system | Adenosine | Transcription factors | Nutrient deficiency | Therapeutic applications | Metabolism | SIRT1 protein | Cofactors | Biological activity | Proteins | Life span | Deacetylation | Nicotinamide | Cardiovascular diseases | Heart diseases
Journal Article
Nature (London), ISSN 1476-4687, 04/2017, Volume 545, Issue 7652, pp. 112 - 115
Protease-activated receptors ( PARs) are a family of G-proteincoupled receptors ( GPCRs) that are irreversibly activated by proteolytic cleavage of the N... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Allosteric Site - drug effects | Humans | Receptor, PAR-2 - metabolism | Imidazoles - chemistry | Models, Molecular | Crystallography, X-Ray | Antibodies, Blocking - pharmacology | Imidazoles - pharmacology | Benzimidazoles - chemistry | Receptor, PAR-2 - chemistry | Immunoglobulin Fab Fragments - pharmacology | Receptor, PAR-2 - antagonists & inhibitors | Signal Transduction - drug effects | Antibodies, Blocking - chemistry | Immunoglobulin Fab Fragments - chemistry | Benzyl Alcohols - pharmacology | Benzimidazoles - pharmacology | Ligands | Benzodioxoles - chemistry | Kinetics | Benzodioxoles - pharmacology | Physiological aspects | Cell receptors | Allosteric proteins | Cytochrome | Residues | G protein-coupled receptors | Peptides | Molecular structure | Hydrogen | Homology | Antagonists | Hydrophobicity | Hydrogen bonding | Optimization | Proteins | Lipophilic | Allosteric properties | Imidazole | Cleavage | Inhibition | Thromboembolism | Lysozyme | Hydrogen ion concentration | Deoxyribonucleic acid--DNA | Cultivation | Architecture | Fab | Crystals | Crystallization | Pharmacology | Inflammation | Glycosylation | Computer programs | Chemistry | Diffraction | Antagonist drugs | Lysine | Isoforms | Computer applications | Mutation | Internet | Receptor mechanisms | Binding sites | Glutamine | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 10/2002, Volume 99, Issue 22, pp. 14071 - 14076
Journal Article
Environmental science and pollution research international, ISSN 0944-1344, 9/2014, Volume 21, Issue 18, pp. 10830 - 10839
Pharmaceuticals and other anthropogenic trace contaminants reach wastewaters and are often not satisfactorily eliminated in sewage treatment plants. These... 
Environmental Health | Ecotoxicology | Ecotoxicity | Elimination | Environment, general | Risk assessment | Environment | Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution | Mixture toxicity | Environmental Chemistry | Atmospheric Protection/Air Quality Control/Air Pollution | Monitoring | Pharmaceuticals | Environmental Sciences & Ecology | Life Sciences & Biomedicine | Science & Technology | Environmental Sciences | Valsartan | Waste Water - chemistry | Antihypertensive Agents - analysis | Imidazoles - chemistry | Benzimidazoles - chemistry | Valine - analysis | Acrylates - analysis | Valine - chemistry | Tetrazoles - chemistry | Mass Spectrometry | Chromatography, Liquid | Thiophenes - analysis | Molecular Structure | Tetrazoles - analysis | Biphenyl Compounds - chemistry | Angiotensin II Type 1 Receptor Blockers - analysis | Biodegradation, Environmental | Angiotensin II Type 1 Receptor Blockers - chemistry | Acrylates - chemistry | Valine - analogs & derivatives | Environmental Monitoring - methods | Water Pollutants, Chemical - chemistry | Water Pollutants, Chemical - analysis | Benzimidazoles - analysis | Biphenyl Compounds - analysis | Antihypertensive Agents - chemistry | Waste Disposal, Fluid - methods | Rivers - chemistry | Environmental Monitoring - statistics & numerical data | Imidazoles - analysis | Thiophenes - chemistry | Germany | Antihypertensive drugs | Water, Underground | Sewage | Purification | Water treatment plants | Drugs | Drinking water | Water treatment | Antihypertensives | Surface water | Effluents | Sewage treatment plants | Beta blockers | Chromatography | Index Medicus | Sewage treatment | Risk | Water pollution | Waste water
Journal Article