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Nature (London), ISSN 1476-4687, 2018, Volume 556, Issue 7699, pp. 103 - 107
A challenge in the treatment of Staphylococcus aureus infections is the high prevalence of methicillin-resistant S. aureus (MRSA) strains and the formation of... 
SYSTEM | IN-VITRO | ST1926 | MULTIDISCIPLINARY SCIENCES | CD437 | RESISTANCE | GRARS | AGENTS | ENDOCARDITIS | Caenorhabditis elegans - microbiology | Naphthols - toxicity | Benzoates - therapeutic use | Benzoates - chemistry | Humans | Naphthols - chemistry | Methicillin-Resistant Staphylococcus aureus - cytology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Retinoids - therapeutic use | Gentamicins - pharmacology | Retinoids - chemistry | Anti-Bacterial Agents - adverse effects | Staphylococcal Infections - microbiology | Cell Death - drug effects | Drug Evaluation, Preclinical | Methicillin-Resistant Staphylococcus aureus - genetics | Disease Models, Animal | Cell Line | Staphylococcal Infections - drug therapy | Gentamicins - therapeutic use | Naphthols - therapeutic use | Retinoids - toxicity | Methicillin-Resistant Staphylococcus aureus - drug effects | Naphthols - pharmacology | Molecular Dynamics Simulation | Drug Synergism | Methicillin-Resistant Staphylococcus aureus - growth & development | Animals | Anti-Bacterial Agents - classification | Benzoates - toxicity | Caenorhabditis elegans - drug effects | Benzoates - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Lipid Bilayers - chemistry | Mutation | Retinoids - pharmacology | Dosage and administration | Retinoids | Antibiotics | Drug therapy | Staphylococcus aureus infections | Membranes | Toxicity | Gentamicin | Chronic infection | Gram-positive bacteria | Molecular dynamics | Cytotoxicity | Lipids | Infections | Drug resistance | Synergism | Optimization | Lipid bilayers | Ovarian cancer | Methicillin | Signal transduction | Bacteria | Subpopulations | Bacterial infections | Computer simulation | Staphylococcus infections | Antimicrobial agents | New classes
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2008, Volume 359, Issue 12, pp. 1225 - 1237
In a multicenter trial, 20,332 patients who had recently had an ischemic stroke were randomly assigned to receive either telmisartan or placebo. All patients... 
MORTALITY | HIGH-RISK PATIENTS | DESIGN | RAMIPRIL | RATIONALE | DOUBLE-BLIND | VASCULAR EVENTS | COMBINATION | UMCG Approved | BLOOD-PRESSURE | RANDOMIZED TRIAL | TRIAL | MEDICINE, GENERAL & INTERNAL | MORBIDITY | Benzoates - adverse effects | Myocardial Infarction - epidemiology | Benzoates - therapeutic use | Follow-Up Studies | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | Secondary Prevention | Heart Failure - prevention & control | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Treatment Failure | Angiotensin-Converting Enzyme Inhibitors - adverse effects | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Blood Pressure - drug effects | Benzimidazoles - adverse effects | Heart Failure - epidemiology | Benzimidazoles - therapeutic use | Stroke - prevention & control | Kaplan-Meier Estimate | Stroke - drug therapy | Diabetes Mellitus - epidemiology | Creatinine - blood | Potassium - blood | Aged | Myocardial Infarction - prevention & control | Stroke (Disease) | Prevention | Usage | Health aspects | Telmisartan | Medical research | Stroke | Blood pressure | Index Medicus | Abridged Index Medicus | Blood Pressure | Creatinine | Recurrence | Benzimidazoles | Cardiovascular Diseases | Benzoates | Diabetes Mellitus | Geriatry and gerontology | Life Sciences | Human health and pathology | Myocardial Infarction | Angiotensin-Converting Enzyme Inhibitors | Heart Failure | Potassium | Cardiology and cardiovascular system | Original | Benzimidazoles/adverse effects/therapeutic use | Diabetes Mellitus/epidemiology | Angiotensin-Converting Enzyme Inhibitors/adverse effects/therapeutic use | Recurrence/prevention & control | Stroke/drug therapy/prevention & control | MEDICIN OCH HÄLSOVETENSKAP | Creatinine/blood | Potassium/blood | Blood Pressure/drug effects | Cardiovascular Diseases/epidemiology/mortality/prevention & control | Benzoates/adverse effects/therapeutic use | Myocardial Infarction/epidemiology/prevention & control | Kaplan-Meiers Estimate | MEDICAL AND HEALTH SCIENCES | Heart Failure/epidemiology/prevention & control
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2008, Volume 359, Issue 12, pp. 1238 - 1251
In this large clinical trial, aspirin plus extended-release dipyridamole was found to have an efficacy similar to that of clopidogrel in the prevention of... 
ACTIVE CONTROLLED-TRIALS | HIGH-RISK PATIENTS | TICLOPIDINE | TRANSIENT ISCHEMIC ATTACK | DOUBLE-BLIND | PREVENTION | RANDOMIZED CONTROLLED-TRIAL | ARTERIAL ORIGIN ESPRIT | CEREBRAL-ISCHEMIA | UMCG Approved | NON-INFERIORITY TRIALS | ISSUES | MEDICINE, GENERAL & INTERNAL | PLACEBO | DESIGN | WARFARIN | REGIMENS | Myocardial Infarction - epidemiology | Benzoates - therapeutic use | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Risk | Secondary Prevention | Aspirin - administration & dosage | Vascular Diseases - mortality | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - adverse effects | Dipyridamole - adverse effects | Female | Stroke - epidemiology | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Dipyridamole - therapeutic use | Benzimidazoles - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Brain Ischemia - epidemiology | Stroke - prevention & control | Double-Blind Method | Kaplan-Meier Estimate | Proportional Hazards Models | Brain Ischemia - prevention & control | Factor Analysis, Statistical | Stroke - drug therapy | Ticlopidine - analogs & derivatives | Aged | Hemorrhage - chemically induced | Delayed-Action Preparations | Stroke (Disease) | Aspirin | Usage | Care and treatment | Dipyridamole | Clopidogrel | Health aspects | Stroke | Index Medicus | Abridged Index Medicus | Recurrence | Brain Ischemia | Benzimidazoles | Follow-Up Studies | Neurons and Cognition | Cognition | Hemorrhage | Drug Delivery Systems | Life Sciences | Angiotensin II Type 1 Receptor Blockers | Angiotensin-Converting Enzyme Inhibitors | Vascular Diseases | Mental Status Schedule | Retrospective Studies | Severity of Illness Index | Disability Evaluation | Benzoates | Drug Administration Schedule | International Cooperation | Ticlopidine | Myocardial Infarction | Platelet Aggregation Inhibitors | Santé publique et épidémiologie | Original | Dipyridamole/adverse effects/therapeutic use | Angiotensin-Converting Enzyme Inhibitors/therapeutic use | Recurrence/prevention & control | Benzoates/therapeutic use | Brain Ischemia/epidemiology/prevention & control | MEDICIN OCH HÄLSOVETENSKAP | Platelet Aggregation Inhibitors/administration & dosage/adverse | Combination | MEDICAL AND HEALTH SCIENCES | Aspirin/administration & dosage/adverse effects | Myocardial Infarction/epidemiology | Factor Analysis | Benzimidazoles/therapeutic use | Drug Therapy | Ticlopidine/adverse effects/analogs & derivatives/therapeutic use | effects/therapeutic use | Vascular Diseases/mortality | Hemorrhage/chemically induced | Stroke/drug therapy/epidemiology/prevention & control | Statistical | Kaplan-Meiers Estimate
Journal Article
Nature chemical biology, ISSN 1552-4469, 2015, Volume 11, Issue 10, pp. 793 - 798
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 386, Issue 10004, pp. 1649 - 1658
Journal Article
Blood, ISSN 1528-0020, 2014, Volume 123, Issue 12, pp. 1818 - 1825
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2008, Volume 372, Issue 9638, pp. 547 - 553
Summary Background Angiotensin receptor blockers (ARB) and angiotensin converting enzyme (ACE) inhibitors are known to reduce proteinuria. Their combination... 
Internal Medicine | COOPERATE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | RENIN-ANGIOTENSIN SYSTEM | DISEASE | PROTEINURIA | CONVERTING ENZYME-INHIBITORS | COMBINATION | NEPHROPATHY | II RECEPTOR BLOCKERS | PROGRESSION | Benzoates - adverse effects | Angiotensin II Type 1 Receptor Blockers - adverse effects | Benzoates - therapeutic use | Follow-Up Studies | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Cardiovascular Diseases - drug therapy | Humans | Middle Aged | Ramipril - administration & dosage | Proteinuria - chemically induced | Cardiovascular Diseases - complications | Glomerular Filtration Rate - drug effects | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Benzimidazoles - administration & dosage | Angiotensin-Converting Enzyme Inhibitors - adverse effects | Ramipril - therapeutic use | Benzimidazoles - adverse effects | Drug Therapy, Combination | Ramipril - adverse effects | Angiotensin II Type 1 Receptor Blockers - administration & dosage | Benzimidazoles - therapeutic use | Kidney - drug effects | Double-Blind Method | Diabetes Mellitus - drug therapy | Proteinuria - metabolism | Angiotensin-Converting Enzyme Inhibitors - administration & dosage | Creatinine - urine | Benzoates - administration & dosage | Creatinine - blood | Aged | Urine | Drugs | Studies | Kidneys | Disease | Clinical trials | Risk | ACE inhibitors | Index Medicus | Abridged Index Medicus
Journal Article