X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (8602) 8602
Newsletter (7) 7
Book Chapter (4) 4
Book / eBook (2) 2
Dissertation (2) 2
Reference (2) 2
Conference Proceeding (1) 1
Journal / eJournal (1) 1
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (4092) 4092
benzoates - pharmacology (3331) 3331
humans (2787) 2787
male (2487) 2487
rats (1955) 1955
benzoates - metabolism (1946) 1946
female (1510) 1510
mice (1164) 1164
pharmacology & pharmacy (1033) 1033
biochemistry & molecular biology (953) 953
benzoates (935) 935
benzoates - therapeutic use (877) 877
benzoic acid (849) 849
kinetics (815) 815
benzoates - chemistry (728) 728
metabolism (687) 687
microbiology (624) 624
time factors (613) 613
research (569) 569
in vitro techniques (550) 550
dose-response relationship, drug (546) 546
analysis (530) 530
expression (505) 505
adult (502) 502
benzimidazoles - pharmacology (495) 495
benzoates - administration & dosage (492) 492
cells, cultured (448) 448
rats, sprague-dawley (441) 441
telmisartan (426) 426
hydrogen-ion concentration (422) 422
neurosciences (417) 417
middle aged (416) 416
oxidation-reduction (396) 396
research article (387) 387
liver - metabolism (386) 386
biotechnology & applied microbiology (382) 382
physiological aspects (370) 370
rats, wistar (360) 360
enzymes (352) 352
structure-activity relationship (332) 332
benzimidazoles - therapeutic use (330) 330
benzoate (322) 322
endocrinology & metabolism (319) 319
protein binding (316) 316
molecular sequence data (311) 311
binding sites (308) 308
biodegradation, environmental (308) 308
activation (305) 305
disease models, animal (303) 303
inhibition (302) 302
proteins (296) 296
cell biology (292) 292
chemistry, medicinal (292) 292
degradation (291) 291
oxidative stress (289) 289
chemistry (282) 282
benzoates - pharmacokinetics (281) 281
mice, inbred c57bl (278) 278
nitric oxide (278) 278
aged (276) 276
angiotensin ii type 1 receptor blockers - pharmacology (276) 276
apoptosis (275) 275
cell line (272) 272
carbon isotopes (270) 270
imidazoles - pharmacology (265) 265
toxicology (262) 262
bacteria (258) 258
glycine - analogs & derivatives (256) 256
sodium benzoate (256) 256
cell line, tumor (255) 255
biodegradation (254) 254
enzyme inhibitors - pharmacology (253) 253
gene expression (253) 253
hematology (252) 252
glycine - pharmacology (251) 251
hypertension (247) 247
nitric oxide - metabolism (240) 240
molecular structure (237) 237
cells (236) 236
physiology (235) 235
genes (234) 234
signal transduction - drug effects (230) 230
oncology (227) 227
rabbits (226) 226
apoptosis - drug effects (224) 224
identification (223) 223
metabolites (222) 222
inflammation (221) 221
acid (215) 215
spectrophotometry (215) 215
ligands (214) 214
mutation (212) 212
treatment outcome (210) 210
benzoates - adverse effects (208) 208
peripheral vascular disease (206) 206
rna, messenger - metabolism (205) 205
in-vitro (203) 203
multidisciplinary sciences (202) 202
benzoates - urine (199) 199
hypertension - drug therapy (198) 198
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (8269) 8269
Japanese (161) 161
German (156) 156
Chinese (74) 74
Russian (65) 65
French (61) 61
Italian (21) 21
Spanish (11) 11
Czech (7) 7
Dutch (4) 4
Hungarian (3) 3
Polish (3) 3
Portuguese (3) 3
Ukrainian (3) 3
Danish (1) 1
Korean (1) 1
Norwegian (1) 1
Romanian (1) 1
Slovak (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Drug metabolism and disposition, ISSN 1521-009X, 2012, Volume 40, Issue 9, pp. 1744 - 1756
.... Active uptake clearance (CLactive, (u)), bidirectional passive diffusion (P-diff), intracellular binding, and metabolism were estimated for bosentan, pitavastatin... 
DRUG TRANSPORTERS | IN-VITRO CLEARANCE | CRYOPRESERVED HUMAN HEPATOCYTES | HMG-COA REDUCTASE | PHARMACOLOGY & PHARMACY | ANION TRANSPORTING POLYPEPTIDES | HEPATIC-UPTAKE | HEALTHY-VOLUNTEERS | METABOLIC ENZYMES | RECEPTOR ANTAGONIST | PREDICTION | Antihypertensive Agents - pharmacology | Tetrazoles - pharmacology | Species Specificity | Valsartan | Hypoglycemic Agents - metabolism | Benzoates - metabolism | Humans | Antihypertensive Agents - metabolism | Hepatocytes - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Angiotensin II Type 1 Receptor Blockers - metabolism | Organic Anion Transporters - metabolism | Pyrimidines - metabolism | Quinolines - pharmacology | Tetrazoles - metabolism | Carbamates - metabolism | Dose-Response Relationship, Drug | Fluorobenzenes - pharmacology | Drug Interactions | Hydroxymethylglutaryl-CoA Reductase Inhibitors - metabolism | Biological Transport | Piperidines - pharmacology | Hepatocytes - drug effects | Carbamates - pharmacology | Pravastatin - pharmacology | Fluorobenzenes - metabolism | Piperidines - metabolism | Pravastatin - metabolism | Valine - analogs & derivatives | Rats | Rosuvastatin Calcium | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Hypoglycemic Agents - pharmacology | Quinolines - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Valine - metabolism | Models, Biological | Benzimidazoles - metabolism | Sulfonamides - metabolism | Benzoates - pharmacology | Benzimidazoles - pharmacology | Kinetics | Valine - pharmacology | Organic Anion Transporters - drug effects
Journal Article
Journal Article
Cell metabolism, ISSN 1550-4131, 2008, Volume 8, Issue 6, pp. 468 - 481
Obesity and nutrient homeostasis are linked by mechanisms that are not fully elucidated. Here we describe a secreted protein, adropin, encoded by a gene,... 
HUMDISEASE | PATHOGENESIS | OBESITY | INSULIN-RESISTANCE | FOOD-INTAKE | GLUCOSE | LIVER | ENDOCRINOLOGY & METABOLISM | RECEPTOR | MICE | ADIPOSE-TISSUE | MELANOCORTIN SYSTEM | CELL BIOLOGY | RNA, Small Interfering - genetics | Peptides | Benzoates - chemistry | Benzoates - metabolism | Humans | Leptin - metabolism | Adipose Tissue, White - metabolism | Molecular Sequence Data | Male | RNA, Messenger - metabolism | Obesity - genetics | Benzylamines - metabolism | DNA-Binding Proteins - metabolism | DNA-Binding Proteins - agonists | Proteins - secretion | RNA Interference | Blood Proteins - genetics | Base Sequence | Liver X Receptors | Female | Orphan Nuclear Receptors | Amino Acid Sequence | Proteins - physiology | Fasting | Fatty Liver - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Blood Proteins - secretion | Lipid Metabolism | Mice, Transgenic | Receptors, Cytoplasmic and Nuclear - agonists | Obesity - metabolism | Proteins - genetics | Benzylamines - chemistry | Animals | Energy Metabolism | Blood Proteins - physiology | Adipose Tissue, Brown - metabolism | Mice | RNA, Small Interfering - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Obesity | Physiological aspects | Homeostasis | Biological apparatus and supplies | Insulin resistance | Neuropeptides | Glucose | Diabetes | Universities and colleges | Dextrose
Journal Article
PloS one, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, p. e0145467
Alzheimer's disease (AD) is the major cause of dementia worldwide. The pharmacological activation of nuclear receptors (Liver X receptors: LXRs or Retinoid X... 
WILD-TYPE | AMYLOID BETA-PEPTIDE | ADULT NEUROGENESIS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | SUBVENTRICULAR ZONE | TRANSGENIC MODEL | DENTATE GYRUS | HIPPOCAMPAL NEUROGENESIS | APOLIPOPROTEIN-E | Benzoates - therapeutic use | Cerebral Cortex - pathology | tau Proteins - metabolism | Cognition Disorders - metabolism | Male | Hippocampus - drug effects | Orphan Nuclear Receptors - metabolism | Apolipoproteins E - metabolism | Excitatory Postsynaptic Potentials - drug effects | ATP Binding Cassette Transporter 1 - metabolism | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Gliosis - pathology | Dentate Gyrus - drug effects | Long-Term Potentiation - drug effects | Liver X Receptors | Amyloid beta-Peptides - metabolism | Female | Cerebral Cortex - drug effects | Biomarkers - metabolism | Alzheimer Disease - physiopathology | Cognition Disorders - physiopathology | Dentate Gyrus - metabolism | Orphan Nuclear Receptors - agonists | Neural Stem Cells - drug effects | Alzheimer Disease - drug therapy | Mice, Transgenic | Nuclear Proteins - metabolism | Hippocampus - pathology | Cognition Disorders - drug therapy | Gliosis - complications | Nerve Tissue Proteins - metabolism | Nestin - metabolism | Up-Regulation - drug effects | Hippocampus - metabolism | Cognition Disorders - complications | Animals | Alzheimer Disease - metabolism | Fluorescent Antibody Technique | Benzoates - pharmacology | Protein Biosynthesis - drug effects | Cell Proliferation - drug effects | Benzylamines - pharmacology | Benzylamines - therapeutic use | Dentate Gyrus - pathology | Neural Stem Cells - metabolism | Brain | Advertising executives | Cognition | Apolipoproteins | Alzheimer's disease | Liver | Amyloidogenesis | Peptides | Cognitive ability | Proteins | Receptors | Neurodegeneration | Physiology | Chemical synthesis | Neurodegenerative diseases | Protein biosynthesis | Behavioral sciences | Metabolism | Retinoid X receptors | Nuclear receptors | Dentate gyrus | Gliosis | Molecular modelling | Tau protein | Protein synthesis | Stem cells | Ligands | ATP-binding protein | Hippocampus | Animal models | Cerebral cortex | Lipids | Kinases | Neurogenesis | ABCA1 protein | Reduction | Metabolites | Apolipoprotein E | Rodents | Synaptic plasticity | Dementia disorders | Liver X receptors | Neurons | Pharmacology | Furchgott, Robert F | Cholesterol | Cortex (entorhinal) | Presenilin 1 | Laboratory animals | Alzheimers disease | Animal cognition
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 2, pp. 536 - 541
Soluble epoxide hydrolase (sEH) is an emerging therapeutic target in a number of diseases that have inflammation as a common underlying cause. sEH limits... 
Omega-3-derived epoxides | Obesity | Inflammation | Autophagy | Soluble epoxide hydrolase | PATHWAYS | autophagy | ER STRESS | OMEGA-3-FATTY-ACIDS | MULTIDISCIPLINARY SCIENCES | FATTY-ACIDS | soluble epoxide hydrolase | INDUCED INSULIN-RESISTANCE | EPOXYEICOSANOIDS | inflammation | DOCOSAHEXAENOIC ACID | EICOSAPENTAENOIC ACID | obesity | omega-3-derived epoxides | Epoxy Compounds - metabolism | Inflammation - pathology | Liver - pathology | Cadherins - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Autophagy - physiology | Cytochrome P-450 CYP2E1 - metabolism | Adipose Tissue - metabolism | Inflammation - metabolism | Liver - drug effects | Mice, Mutant Strains | Female | Cadherins - genetics | Fatty Acid Desaturases - genetics | Fatty Acids, Omega-3 - metabolism | Fatty Acid Desaturases - metabolism | Liver - metabolism | Mice, Inbred C57BL | Adipose Tissue - pathology | Enzyme Inhibitors - pharmacology | Mice, Transgenic | 3T3-L1 Cells | Cytochrome P-450 CYP1A1 - metabolism | Obesity - metabolism | Obesity - pathology | Animals | Benzoates - pharmacology | Mice | Phenylurea Compounds - pharmacology | Adipose Tissue - drug effects | Epoxide Hydrolases - antagonists & inhibitors | Adipose tissues | Autophagy (Cytology) | Medical research | Liver | Epoxy compounds | Medicine, Experimental | Research | Health aspects | Obesitat | Liver diseases | Àcids grassos insaturats | Inflamació | Unsaturated fatty acids | Àcids grassos omega-3 | Teixit adipós | Malalties del fetge | Autofàgia | Omega-3 fatty acids | Biological Sciences | omega-3–derived epoxides
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 05/2008, Volume 21, Issue 5, pp. 576 - 581
..., and the most abundant isoform in adipose tissue. PPAR-γ plays a critical role in regulating carbohydrate and lipid metabolisms. In addition, PPAR-γ ligands have modest... 
METABOLIC SYNDROME | NITRIC-OXIDE PRODUCTION | ENDOTHELIAL DYSFUNCTION | LIGANDS | RECEPTOR BLOCKERS | CARDIAC-PERFORMANCE | TROGLITAZONE | PERIPHERAL VASCULAR DISEASE | ANGIOTENSIN-II | EPLERENONE | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Benzoates - therapeutic use | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Transforming Growth Factor beta1 - metabolism | NADPH Oxidases - metabolism | Hypertension - drug therapy | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | PPAR gamma - metabolism | Angiotensin II Type 1 Receptor Blockers - pharmacology | Plasminogen Activator Inhibitor 1 - metabolism | rho-Associated Kinases - metabolism | Protein Kinase C - metabolism | Hypertension - chemically induced | Myocardium - metabolism | Superoxides - metabolism | Rats, Inbred Dahl | Benzimidazoles - therapeutic use | Disease Models, Animal | Collagen Type I - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Hypertrophy, Left Ventricular - etiology | Hypertrophy, Left Ventricular - metabolism | Hypertrophy, Left Ventricular - prevention & control | Sodium Chloride, Dietary - adverse effects | Nitric Oxide Synthase Type III | Rats | Hypertension - metabolism | Myocardium - enzymology | Animals | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | PPAR gamma - agonists | Benzoates - pharmacology | Hypertension - complications | Benzimidazoles - pharmacology | Protein Kinase Inhibitors - pharmacology | Hypertrophy, Left Ventricular - physiopathology | Oxidative Stress - drug effects | Research Design | Ventricular Remodeling - drug effects | Nitric Oxide Synthase Type II - metabolism | Hypertension | Physiological aspects | Drug therapy | Cardiotonic agents | Telmisartan | Cardiac glycosides | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e108994
Background and Objective: Sodium glucose cotransporter 2 (SGLT2) is the main luminal glucose transporter in the kidney. SGLT2 inhibition results in glycosuria... 
CELLS | HYPERGLYCEMIA | SGLT2 | TRANSPORTERS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | INJURY | PPAR-GAMMA AGONISTS | TRANSFORMING GROWTH FACTOR-BETA | PROGRESSION | Benzoates - therapeutic use | Toll-Like Receptor 2 - genetics | Diabetic Nephropathies - etiology | Transforming Growth Factor beta1 - metabolism | Glucose Transporter Type 1 - metabolism | Male | RNA, Messenger - metabolism | Nitric Oxide Synthase Type III - deficiency | Glucosides - therapeutic use | Chemokine CCL2 - metabolism | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - complications | Diabetes Mellitus, Experimental - metabolism | Benzhydryl Compounds - therapeutic use | Diabetic Nephropathies - prevention & control | Benzimidazoles - therapeutic use | Sodium-Glucose Transporter 2 - genetics | Hypoglycemic Agents - therapeutic use | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Albuminuria - etiology | Blood Glucose - analysis | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Chemokine CCL2 - genetics | Transforming Growth Factor beta1 - genetics | Toll-Like Receptor 2 - metabolism | Nitric Oxide Synthase Type III - genetics | Fibronectins - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | Mice, Knockout | Animals | Glucose Transporter Type 1 - genetics | Kidney Tubules, Proximal - metabolism | Benzoates - pharmacology | Benzimidazoles - pharmacology | Benzhydryl Compounds - pharmacology | Fibronectins - genetics | Mice | Streptozocin - toxicity | Blood Glucose - metabolism | Kidney Tubules, Proximal - drug effects | Drugs | Transcription | Syngeneic grafts | Streptozocin | Genomics | Transforming growth factor | Glucose | Macrophages | Blood | Fibronectin | Proteins | Atrophy | Hyperglycemia | Rodents | Toll-like receptors | Physiology | Inhibition | Protein transport | Immune system | Creatinine | Glucose transporter | Medical research | Kidneys | Cytokines | Diabetes mellitus | Reabsorption | Histology | Inflammation | Metabolism | Gene expression | Nephropathy | Sodium | Nitric oxide | Fibrosis | Angiotensin | Insulin resistance | Research design | Kidney diseases | Diabetes | Transporter | Monocyte chemoattractant protein 1 | Kidney transplantation | Best practice
Journal Article
Nature (London), ISSN 1476-4687, 2019, Volume 567, Issue 7746, pp. 123 - 126
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 2136 - 2145.e7
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2010, Volume 285, Issue 2, pp. 1333 - 1342
The biology of the α subunits of hypoxia-inducible factors (HIFα) has expanded from their role in angiogenesis to their current position in the self-renewal... 
IN-VITRO | EMBRYONIC-DEVELOPMENT | FACTOR-1-ALPHA | ADULT SPINAL-CORD | BIOCHEMISTRY & MOLECULAR BIOLOGY | LOWERED OXYGEN | IDENTIFICATION | TUMOR-GROWTH | EXPRESSION | CANCER | PROLYL HYDROXYLASES | Embryonic Stem Cells - metabolism | Transcription, Genetic - drug effects | Cell Hypoxia - physiology | Embryonic Stem Cells - cytology | Benzoates - metabolism | Homeodomain Proteins - metabolism | Humans | Benzamides - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Male | SOXB1 Transcription Factors - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Ependyma - cytology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Response Elements - physiology | Transforming Growth Factor alpha - metabolism | Adult Stem Cells - cytology | Cell Hypoxia - drug effects | Nanog Homeobox Protein | Gene Expression Regulation - physiology | Rats | Ependyma - metabolism | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | Rats, Sprague-Dawley | Gene Expression Regulation - drug effects | p300-CBP Transcription Factors - metabolism | Acetylation - drug effects | Adult Stem Cells - metabolism | Transcription, Genetic - physiology | Animals | Cell Differentiation - drug effects | Octamer Transcription Factor-3 - metabolism | Pharmaceutical Preparations | HeLa Cells | Histones - metabolism | Molecular Basis of Cell and Developmental Biology | Neurological | Oxygen | Stem Cell | Diseases | Stem Cells | Development Differentiation | Histones | Acetylase | Hypoxia | Differentiation | Cell | Neural
Journal Article