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1. Full Text Glycal-Derived δ‑Hydroxy α,β-Unsaturated Aldehydes (Perlin Aldehydes): Versatile Building Blocks in Organic Synthesis
by Reddy, L. Vijaya Raghava and Kumar, Vikas and Sagar, Ram and Shaw, Arun K
Chemical reviews, ISSN 0009-2665, 05/2013, Volume 113, Issue 5, pp. 3605 - 3631
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Quinolines - chemical synthesis | Biological Products - chemical synthesis | Nucleosides - chemical synthesis | Benzodiazepines - chemical synthesis | Aldehydes - chemical synthesis | Pyridines - chemical synthesis | Alcohols - chemical synthesis | Lactams - chemical synthesis | Furans - chemical synthesis | Aldehydes - chemistry | Chemistry Techniques, Synthetic - methods | Usage | Research | Chemical properties | Chemical synthesis | Aldehydes | Glycosylation | Organic chemicals | Index Medicus | Glycols | Synthesis
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2. Full Text Synthesis of DNA-Interactive Pyrrolo[2,1-c][1,4]benzodiazepines (PBDs)
by Antonow, Dyeison and Thurston, David E
Chemical reviews, ISSN 0009-2665, 04/2011, Volume 111, Issue 4, pp. 2815 - 2864
Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Pyrroles - pharmacology | Animals | Benzodiazepines - pharmacology | Pyrroles - chemical synthesis | Benzodiazepines - chemical synthesis | Humans | Benzodiazepines - chemistry | Models, Molecular | Pyrroles - chemistry | DNA - metabolism | Analysis | Benzene | Pyrrole | DNA synthesis | Oxidation-reduction reaction | Chemical properties | Ring formation (Chemistry) | Structure | Deoxyribonucleic acid--DNA | Chemicals | Synthesis | Index Medicus
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3. Full Text Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepines
by Gerratana, Barbara
Medicinal research reviews, ISSN 0198-6325, 03/2012, Volume 32, Issue 2, pp. 254 - 293
sibiromycin | tomaymycin | lincomycin | biosynthesis | DNA alkylation | pyrrolobenzodiazepines | anthramycin | SJG‐136 | DSB‐120 | anticancer | Pyrrolobenzodiazepines | DSB-120 | Lincomycin | Tomaymycin | Biosynthesis | Anticancer | Anthramycin | Sibiromycin | SJG-136 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Pyrroles - metabolism | Multigene Family | Antineoplastic Agents, Alkylating - chemical synthesis | Benzodiazepines - pharmacology | Benzodiazepines - chemical synthesis | Models, Molecular | Antineoplastic Agents, Alkylating - pharmacology | Structure-Activity Relationship | DNA - metabolism | Pyrroles - pharmacology | Pyrroles - chemical synthesis | Anthramycin - biosynthesis | Actinobacteria - genetics | Actinobacteria - metabolism | Aminoglycosides - biosynthesis | Benzodiazepines - metabolism | Antineoplastic Agents, Alkylating - metabolism | Index Medicus
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4. Full Text A robotic platform for flow synthesis of organic compounds informed by AI planning
by Coley, Connor W and Thomas, Dale A and Lummiss, Justin A. M and Jaworski, Jonathan N and Breen, Christopher P and Schultz, Victor and Hart, Travis and Fishman, Joshua S and Rogers, Luke and Gao, Hanyu and Hicklin, Robert W and Plehiers, Pieter P and Byington, Joshua and Piotti, John S and Green, William H and Hart, A. John and Jamison, Timothy F and Jensen, Klavs F
Science (American Association for the Advancement of Science), ISSN 0036-8075, 08/2019, Volume 365, Issue 6453, p. 557
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Intervention | Stoichiometry | Robotics | Complexity | Reactors | Chemists | Configurations | Chemical synthesis | Diazepam | Organic compounds | Solvents | Platforms | Automation | Warfarin | Integration | Aspirin | Antiinflammatory agents | Configuration management | Chemical reactions | Inflammation | Celecoxib | Separators | Secnidazole | Benzodiazepines | Continuous flow | Substrates | Flow | Computer programs | Inlets | User requirements | Organic chemistry | Robot arms | Chemistry | Algorithms | Computer applications | Reagents | Recipes | Software | Lidocaine | Protocol (computers) | Artificial intelligence | Investment | Index Medicus
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5. Full Text (Z)‑Stereoselective Synthesis of Mono- and Bis-heterocyclic Benzimidazol-2-ones via Cascade Processes Coupled with the Ugi Multicomponent Reaction
by Xu, Zhigang and Martinez-Ariza, Guillermo and Cappelli, Alexandra P and Roberts, Sue A and Hulme, Christopher
Journal of organic chemistry, ISSN 0022-3263, 09/2015, Volume 80, Issue 18, pp. 9007 - 9015
Physical Sciences | Chemistry | Chemistry, Organic | Science & Technology | Cyclization | Heterocyclic Compounds - chemistry | Stereoisomerism | Benzimidazoles - chemical synthesis | Crystallography, X-Ray | Heterocyclic Compounds - chemical synthesis | Molecular Structure | Benzimidazoles - chemistry | X-ray crystallography | Usage | Research | Chemical properties | Chemical synthesis | Structure | Benzodiazepines | Index Medicus
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6. Full Text Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing ‘click’ chemistry: DNA-binding affinity and anticancer activity
by Kamal, Ahmed and Shankaraiah, N and Devaiah, V and Laxma Reddy, K and Juvekar, Aarti and Sen, Subrata and Kurian, Nisha and Zingde, Surekha
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2008, Volume 18, Issue 4, pp. 1468 - 1473
1,2,3-Triazoles | DNA-binding affinity | Pyrrolo[2,1- c][1,4]benzodiazepines | Anticancer activity | Pyrrolo[2,1-c][1,4]benzodiazepines | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Benzodiazepines - pharmacology | Benzodiazepines - chemical synthesis | Triazoles - chemistry | Antineoplastic Agents - chemical synthesis | Humans | DNA - metabolism | Antineoplastic Agents - chemistry | Neoplasms - drug therapy | Triazoles - pharmacology | DNA - chemistry | Pyrroles - pharmacology | Pyrroles - chemical synthesis | Neoplasms - genetics | Benzodiazepines - chemistry | Cell Line, Tumor | Pyrroles - chemistry | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | Kinetics | Care and treatment | Benzodiazepines | Cancer | Index Medicus
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7. Full Text Synthesis of [125I]iodoDPA-713: A new probe for imaging inflammation
by Wang, Haofan and Pullambhatla, Mrudula and Guilarte, Tomas R and Mease, Ronnie C and Pomper, Martin G
Biochemical and biophysical research communications, ISSN 0006-291X, 11/2009, Volume 389, Issue 1, pp. 80 - 83
Peripheral benzodiazepine receptor | Autoradiography | Small animal imaging | Pyrazolopyrimidine | Translocator protein | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Brain - diagnostic imaging | Pyrazoles - chemical synthesis | Pyrimidines - chemical synthesis | Radiopharmaceuticals - chemical synthesis | Pyrimidines - chemistry | Acetamides - chemical synthesis | Pyrazoles - chemistry | Molecular Probes - pharmacokinetics | Female | Inflammation - diagnostic imaging | Pyrazoles - pharmacokinetics | Receptors, GABA - analysis | Radiopharmaceuticals - chemistry | Radiopharmaceuticals - pharmacokinetics | Acetamides - pharmacokinetics | Rats | Molecular Probes - chemical synthesis | Mice, Inbred Strains | Molecular Probes - chemistry | Acetamides - chemistry | Animals | Receptors, GABA - metabolism | Pyrimidines - pharmacokinetics | Mice | Pneumonia - diagnostic imaging | Tomography, Emission-Computed | Amides | Diagnostic imaging | Inflammation | Investigations | Benzodiazepines | Index Medicus | ACETAMIDE | LUNGS | RATS | IN VIVO | IMPURITIES | IODINE 125 | RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS | RADIOPHARMACEUTICALS | RADIOCHEMISTRY | IN VITRO | INFLAMMATION | SYNTHESIS | RADIOLOGY AND NUCLEAR MEDICINE | RADIOACTIVITY | RECEPTORS | AUTORADIOGRAPHY | SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY | peripheral benzodiazepine receptor | small animal imaging | translocator protein | autoradiography | pyrazolopyrimidine
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8. Full Text Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole–pyrrolo[2,1- c][1,4]benzodiazepine conjugates
by Kamal, Ahmed and Reddy, K. Srinivasa and Khan, M. Naseer A and Shetti, Rajesh V.C.R.N.C and Ramaiah, M. Janaki and Pushpavalli, S.N.C.V.L and Srinivas, Chatla and Pal-Bhadra, Manika and Chourasia, Mukesh and Sastry, G. Narahari and Juvekar, Aarti and Zingde, Surekha and Barkume, Madan
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2010, Volume 18, Issue 13, pp. 4747 - 4761
Benzoxazole, DNA-binding affinity | Molecular modelling |