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Expert Review of Anti-Infective Therapy, ISSN 1478-7210, 2014, Volume 12, Issue 7, pp. 763 - 773
About 2% of the world's population is estimated to be chronically infected with hepatitis C virus (HCV). These chronic carriers are at risk of developing liver... 
Daclatasvir | MK-8742 | Ombitasvir | Interferon-free | Ledipasvir | MK-5172 | Asunaprevir | ABT-450 | Sofosbuvir | Dasabuvir | CONTROLLED-TRIAL | PLUS RIBAVIRIN | LIVER-TRANSPLANTATION | ombitasvir | asunaprevir | HCV INFECTION | daclatasvir | interferon-free | ledipasvir | sofosbuvir | SUSTAINED VIROLOGICAL RESPONSE | PROTEASE INHIBITOR | TREATMENT OPTIONS | GENOTYPE 1 INFECTION | PHARMACOLOGY & PHARMACY | dasabuvir | CHRONIC VIRAL-HEPATITIS | DISEASE PROGRESSION | Uridine Monophosphate - administration & dosage | Quinoxalines - adverse effects | Anilides - therapeutic use | Isoquinolines - adverse effects | Hepatitis C - drug therapy | Anilides - adverse effects | Humans | Imidazoles - administration & dosage | Benzofurans - administration & dosage | Carbamates - administration & dosage | Uracil - administration & dosage | Ribavirin - administration & dosage | Uridine Monophosphate - adverse effects | Imidazoles - therapeutic use | Hepatitis C - prevention & control | Quinoxalines - therapeutic use | Uridine Monophosphate - therapeutic use | Disease Eradication | Benzofurans - therapeutic use | Quinoxalines - administration & dosage | Antiviral Agents - therapeutic use | Imidazoles - adverse effects | Ribavirin - therapeutic use | Uracil - therapeutic use | Clinical Trials as Topic | Macrocyclic Compounds - adverse effects | Antiviral Agents - administration & dosage | Benzofurans - adverse effects | Macrocyclic Compounds - therapeutic use | Uracil - adverse effects | Anilides - administration & dosage | Sulfonamides - therapeutic use | Ribavirin - adverse effects | Antiviral Agents - adverse effects | Uridine Monophosphate - analogs & derivatives | Isoquinolines - therapeutic use | Sulfonamides - adverse effects | Carbamates - adverse effects | Macrocyclic Compounds - administration & dosage | Carbamates - therapeutic use | Hepacivirus | Isoquinolines - administration & dosage | Drug Combinations | Sulfonamides - administration & dosage | Uracil - analogs & derivatives
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 03/2013, Volume 48, Issue 4-5, pp. 595 - 603
The aim of this study was to develop novel multiple agents loaded poly ( , -lactide-co-glycolide acid) (PLGA) nanoparticles (NPs) and evaluate their potential... 
Nanoparticles | PLGA | Brain delivery | Inner ear administration | NERVOUS-SYSTEM | DRUG-DELIVERY | FOCAL CEREBRAL-ISCHEMIA | GUINEA-PIGS | RAT MODEL | FREE-RADICALS | ISCHEMIA-REPERFUSION INJURY | SALVIANOLIC ACID-B | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | BLOOD | Ginsenosides - cerebrospinal fluid | Carotid Arteries | Nanoparticles - chemistry | Reperfusion Injury - drug therapy | Drug Carriers - administration & dosage | Benzofurans - administration & dosage | Male | Diterpenes, Abietane - administration & dosage | Diterpenes, Abietane - pharmacokinetics | Drug Carriers - chemistry | Benzofurans - pharmacokinetics | Brain - metabolism | Diterpenes, Abietane - cerebrospinal fluid | Neuroprotective Agents - pharmacokinetics | Benzofurans - cerebrospinal fluid | Ginsenosides - administration & dosage | Neuroprotective Agents - cerebrospinal fluid | Neuroprotective Agents - administration & dosage | Lactic Acid - administration & dosage | Reperfusion Injury - metabolism | Polyglycolic Acid - administration & dosage | Drug Administration Routes | Guinea Pigs | Lactic Acid - chemistry | Ear, Inner | Panax notoginseng | Particle Size | Animals | Polyglycolic Acid - chemistry | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Ginsenosides - pharmacokinetics | Drugs | Drug delivery systems | Surface active agents | Nitric oxide | Drugstores | Superoxide | Sulfates | Vehicles
Journal Article
Cancer, ISSN 0008-543X, 04/2015, Volume 121, Issue 8, pp. 1223 - 1230
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 01/2016, Volume 62, Issue 1, pp. 32 - 36
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9973, pp. 1075 - 1086
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 29, pp. 13075 - 13080
Activation of the B-cell antigen receptor (BCR) signaling pathway contributes to the initiation and maintenance of B-cell malignancies and autoimmune diseases.... 
T lymphocytes | Animal models | Disease models | Gels | B lymphocytes | B cell lymphoma | Arthritis | Mice | Autoimmune diseases | Tumors | X-linked agammaglobulinemia | Lymphoma | COLLAGEN-INDUCED ARTHRITIS | THERAPY | RITUXIMAB | MULTIDISCIPLINARY SCIENCES | lymphoma | DOGS | FAMILY KINASES | BTK | RECEPTOR | DEPLETION | MICE | Arthritis, Experimental - drug therapy | Pyrazoles - therapeutic use | Humans | Benzofurans - administration & dosage | Benzofurans - pharmacology | Autoantibodies - biosynthesis | Pyrimidines - chemistry | Benzofurans - chemistry | Protein Kinase Inhibitors - chemistry | Pyrazoles - chemistry | Lymphoma, B-Cell - enzymology | Autoimmune Diseases - drug therapy | Disease Models, Animal | Lymphoma, B-Cell - drug therapy | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Benzofurans - therapeutic use | Autoimmune Diseases - enzymology | Administration, Oral | Pyrimidines - administration & dosage | Treatment Outcome | Pyrimidines - pharmacology | Receptors, Antigen, B-Cell - immunology | B-Lymphocytes - drug effects | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | B-Lymphocytes - immunology | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Dogs | Protein Kinase Inhibitors - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Cell receptors | Models | Lymphomas | Research | Properties | Biological Sciences
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2013, Volume 49, Issue 13, pp. 2791 - 2797
Journal Article
Gut, ISSN 0017-5749, 09/2017, Volume 66, Issue 9, pp. 1611 - 1622
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 04/2017, Volume 35, Issue 11, pp. 1231 - 1238
Purpose This phase I trial evaluated epigenetic modulation of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor by using a histone... 
HYDROXAMIC ACID | TRIAL | ONCOLOGY | SUNITINIB | LYMPHOMA | SORAFENIB | RECHALLENGE | Kidney Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Epigenesis, Genetic | Humans | Middle Aged | Histone Deacetylase Inhibitors - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Carcinoma, Renal Cell - genetics | Benzofurans - administration & dosage | Male | Alanine Transaminase - blood | Benzofurans - blood | Fatigue - chemically induced | Vascular Endothelial Growth Factor A - genetics | Histone Deacetylase Inhibitors - blood | Benzofurans - pharmacokinetics | Young Adult | Histone Deacetylase Inhibitors - pharmacokinetics | Angiogenesis Inhibitors - administration & dosage | Angiogenesis Inhibitors - therapeutic use | Hydroxamic Acids - administration & dosage | Adult | Female | Acetylation | Carcinoma, Renal Cell - drug therapy | Neutropenia - chemically induced | Drug Resistance | Histone Deacetylase 2 - genetics | Hydroxamic Acids - blood | Gene Expression | Pyrimidines - administration & dosage | Vascular Endothelial Growth Factor A - blood | Treatment Outcome | Thrombocytopenia - chemically induced | Disease Progression | Hydroxamic Acids - pharmacokinetics | Disease-Free Survival | Maximum Tolerated Dose | Aspartate Aminotransferases - blood | Aged | Histones - metabolism | Kidney Neoplasms - drug therapy | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | Index Medicus | ORIGINAL REPORTS
Journal Article
Journal Article
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9973, pp. 1087 - 1097
Journal Article