X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2147) 2147
Publication (116) 116
Book Review (72) 72
Magazine Article (8) 8
Book Chapter (5) 5
Conference Proceeding (2) 2
Government Document (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1753) 1753
animals (1121) 1121
benzophenanthridines (1053) 1053
alkaloids (882) 882
phenanthridines - pharmacology (673) 673
humans (666) 666
protein kinase c - antagonists & inhibitors (579) 579
male (550) 550
benzophenanthridines - pharmacology (542) 542
rats (519) 519
enzyme inhibitors - pharmacology (518) 518
protein kinase c - metabolism (452) 452
sanguinarine (353) 353
pharmacology & pharmacy (319) 319
isoquinolines (302) 302
benzophenanthridine alkaloids (297) 297
alkaloids - pharmacology (290) 290
biochemistry & molecular biology (272) 272
mice (269) 269
protein kinase c (266) 266
chelerythrine (262) 262
protein-kinase-c (248) 248
female (243) 243
activation (238) 238
cells, cultured (225) 225
dose-response relationship, drug (222) 222
isoquinolines - pharmacology (210) 210
apoptosis (203) 203
phosphorylation (200) 200
rats, sprague-dawley (199) 199
in vitro techniques (188) 188
cell biology (169) 169
benzophenanthridines - chemistry (163) 163
cells (157) 157
tetradecanoylphorbol acetate - pharmacology (157) 157
physiology (156) 156
calcium - metabolism (153) 153
chemistry, medicinal (150) 150
apoptosis - drug effects (148) 148
signal transduction (148) 148
cell line, tumor (142) 142
rats, wistar (137) 137
dentistry (135) 135
expression (135) 135
plant sciences (132) 132
time factors (130) 130
signal transduction - drug effects (129) 129
inhibition (128) 128
neurosciences (128) 128
protein kinases (127) 127
protein kinase c - physiology (124) 124
alkaloids - chemistry (119) 119
analysis (113) 113
molecular structure (113) 113
research (113) 113
antineoplastic agents - pharmacology (110) 110
cardiac & cardiovascular systems (107) 107
in-vitro (106) 106
cell line (105) 105
proteins (102) 102
chemistry, organic (101) 101
enzyme activation (101) 101
alkaloids - therapeutic use (100) 100
physiological aspects (99) 99
oncology (98) 98
indoles - pharmacology (95) 95
cell survival - drug effects (91) 91
myocardium - metabolism (91) 91
isoquinolines - chemistry (90) 90
kinetics (88) 88
cancer (86) 86
rabbits (86) 86
enzyme activation - drug effects (83) 83
kinases (82) 82
adult (81) 81
inhibitor (81) 81
toxicology (78) 78
calcium (77) 77
blotting, western (76) 76
benzophenanthridine (75) 75
patch-clamp techniques (75) 75
staurosporine - pharmacology (75) 75
cell proliferation - drug effects (74) 74
chemistry, multidisciplinary (72) 72
papaveraceae (72) 72
protein kinase inhibitors - pharmacology (72) 72
signal transduction - physiology (72) 72
tumor cells, cultured (71) 71
peripheral vascular disease (70) 70
binding (68) 68
dna (68) 68
dental plaque - prevention & control (67) 67
isoenzymes - metabolism (67) 67
naphthalenes - pharmacology (67) 67
plant extracts - pharmacology (65) 65
biophysics (62) 62
chemistry, analytical (62) 62
down-regulation (62) 62
induction (62) 62
receptor (61) 61
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2041) 2041
Chinese (46) 46
Russian (19) 19
German (12) 12
French (9) 9
Czech (7) 7
Japanese (6) 6
Italian (4) 4
Spanish (4) 4
Ukrainian (4) 4
Slovak (2) 2
Hungarian (1) 1
Polish (1) 1
Portuguese (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


British Journal of Pharmacology, ISSN 0007-1188, 08/2016, Volume 173, Issue 16, pp. 2543 - 2554
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1591 - 1602
The mechanistic target of rapamycin (mTOR) is hyperactivated in many types of cancer, rendering it a compelling drug-target; however, the impact of mTOR... 
RAPAMYCIN | MEDICINE, RESEARCH & EXPERIMENTAL | PATHWAY | MUTATION | KINASE INHIBITORS | PROLIFERATION | CELL-GROWTH | PTEN-DEFICIENT | CANCER | CONTRIBUTES | Gas Chromatography-Mass Spectrometry | Humans | Glutamine - metabolism | Male | Neoplasm Proteins - antagonists & inhibitors | Purines - administration & dosage | Indoles - administration & dosage | Benzophenanthridines - therapeutic use | Glioblastoma - metabolism | Purines - therapeutic use | Neoplasm Proteins - genetics | Glutaminase - biosynthesis | Magnetic Resonance Spectroscopy | Benzophenanthridines - administration & dosage | Brain Neoplasms - drug therapy | Benzophenanthridines - pharmacology | Drug Synergism | Energy Metabolism | Signal Transduction - drug effects | Mice, Nude | Glioblastoma - pathology | Cell Line, Tumor | Indoles - therapeutic use | Mice | Mice, Inbred BALB C | Glioblastoma - drug therapy | Glutaminase - physiology | Neoplasm Proteins - physiology | Brain Neoplasms - pathology | Molecular Targeted Therapy | Brain Neoplasms - metabolism | TOR Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Ketoglutaric Acids - metabolism | Neoplasm Proteins - biosynthesis | Purines - pharmacology | RNA, Small Interfering - pharmacology | Temporal Lobe - metabolism | Glutaminase - antagonists & inhibitors | Citric Acid Cycle | Xenograft Model Antitumor Assays | Rotarod Performance Test | Animals | Metabolome - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Glycolysis | Signal Transduction - physiology | Aged | Glutamic Acid - metabolism | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - physiology | Glutaminase - genetics | Pharmacology, Experimental | Oncology, Experimental | Glutamine metabolism | Research | Drug therapy | Drug resistance | Health aspects | Glioblastoma multiforme | Cancer | Medical research | Enzymes | Brain cancer | Neurosurgery | Glucose | Kinases | Metabolism | Carbon | Cancer therapies | Medicine | Cell growth | Brain research | Laboratory animals | Tumors | University graduates | Index Medicus | Abridged Index Medicus | Oncology
Journal Article
Organic Letters, ISSN 1523-7060, 12/2015, Volume 17, Issue 24, pp. 6078 - 6081
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2014, Volume 90, Issue 3, pp. 226 - 234
Basal-like breast cancer (BLBC) remains a great challenge because of its clinically aggressive nature and lack of effective targeted therapy. We analyzed the... 
Dihydrofolate reductase (DHFR) | Mice | Sanguinarine | Basal-like breast cancer | STAT3 | Apoptosis | CARCINOMA-CELLS | SUBTYPE | ACTIVATION | BENZOPHENANTHRIDINE ALKALOID SANGUINARINE | PHOSPHORYLATION | PHENOTYPE | TUMOR-CELLS | PHARMACOLOGY & PHARMACY | CYCLIN-D1 | EXPRESSION | Methotrexate - pharmacology | Neoplasm Transplantation | Isoquinolines - adverse effects | Tetrahydrofolate Dehydrogenase - chemistry | Apoptosis - drug effects | Humans | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Necrosis | Folic Acid Antagonists - therapeutic use | Breast Neoplasms - enzymology | Isoquinolines - pharmacology | Benzophenanthridines - therapeutic use | Neoplasms, Basal Cell - enzymology | Female | Neoplasms, Basal Cell - drug therapy | Antineoplastic Agents, Phytogenic - therapeutic use | Folic Acid Antagonists - adverse effects | Antineoplastic Agents, Phytogenic - adverse effects | Cell Survival - drug effects | Benzophenanthridines - adverse effects | Neoplasms, Basal Cell - pathology | Random Allocation | Mice, Inbred Strains | Breast Neoplasms - drug therapy | Benzophenanthridines - pharmacology | Tetrahydrofolate Dehydrogenase - metabolism | Cell Movement - drug effects | Animals | Tumor Burden - drug effects | Breast Neoplasms - pathology | Cell Line, Tumor | Isoquinolines - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Folic Acid Antagonists - pharmacology | Breast cancer | Dihydrofolate reductase | Index Medicus
Journal Article
Journal Article
Journal Article