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Current Medicinal Chemistry, ISSN 0929-8673, 09/2011, Volume 18, Issue 26, pp. 4019 - 4028
Hepatitis C virus (HCV) infection is a significant world health threat with frequently ineffective problem existed in the present treatment, thus representing... 
3D-QSAR | Molecular dynamics | Benzothiadiazine scaffold-based inhibitors | HCV NS5B | Molecular docking | CoMFA | CoMSIA | NONNUCLEOSIDE INHIBITORS | PLUS RIBAVIRIN | CHEMISTRY, MEDICINAL | DEPENDENT RNA-POLYMERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HCVNS5B POLYMERASE | molecular dynamics | ALLOSTERIC INHIBITORS | SIMILARITY INDEXES | benzothiadiazine scaffold-based inhibitors | molecular docking | ANALYSIS COMSIA | PHARMACOLOGY & PHARMACY | PART 1 | FIELD ANALYSIS COMFA | VIRAL-HEPATITIS | Hepatitis C - drug therapy | Humans | Hepacivirus - genetics | Hepacivirus - chemistry | Molecular Targeted Therapy | Hepacivirus - metabolism | Viral Nonstructural Proteins - chemistry | Enzyme Inhibitors - chemistry | Hepatitis C - epidemiology | Drug Design | Inhibitory Concentration 50 | Drug Evaluation, Preclinical | Binding Sites | Quantitative Structure-Activity Relationship | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Models, Molecular | Hepatitis C - genetics | Benzothiadiazines - pharmacology | Drug Discovery | Enzyme Inhibitors - therapeutic use | Benzothiadiazines - therapeutic use | Molecular Dynamics Simulation | Hepacivirus - enzymology | Animals | Small Molecule Libraries | Benzothiadiazines - chemistry | Protein Binding | Benzothiadiazines - metabolism | Viral Nonstructural Proteins - metabolism | Viral Nonstructural Proteins - antagonists & inhibitors
Journal Article
Acta biomaterialia, ISSN 1742-7061, 2017, Volume 58, pp. 421 - 431
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 2014, Volume 36, Issue 12, pp. 2047 - 2063.e3
Journal Article
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2007, Volume 51, Issue 12, pp. 4290 - 4296
Journal Article
The international journal of neuropsychopharmacology, ISSN 1461-1457, 08/2014, Volume 17, Issue 8, pp. 1321 - 1326
Several lines of evidence indicate that ketamine has a rapid antidepressant-like effect in rodents and humans, but underlying mechanisms are unclear. In the... 
Ketamine | AMPA receptors | Serotonin | nicotinic acetylcholine receptors | Dorsal raphe nucleus | α 4 β 2 -nicotinic acetylcholine receptors | α 4 β 2-nicotinic acetylcholine receptors | Key words AMPA receptors | PSYCHIATRY | DORSAL RAPHE | MECHANISMS | NEUROSCIENCES | CLINICAL NEUROLOGY | alphabeta-nicotinic acetylcholine receptors | NUCLEUS | 5-HT NEURONAL-ACTIVITY | PHARMACOLOGY & PHARMACY | PROJECTIONS | BLOCKADE | Nicotinic Antagonists - administration & dosage | Dihydro-beta-Erythroidine - pharmacology | Male | Ketamine - antagonists & inhibitors | Nicotinic Antagonists - pharmacology | Ketamine - administration & dosage | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Prefrontal Cortex - drug effects | Injections, Subcutaneous | Antidepressive Agents - pharmacology | Receptors, AMPA - metabolism | Spermine - analogs & derivatives | Receptors, Nicotinic - metabolism | Microinjections | Quinoxalines - administration & dosage | Spermine - administration & dosage | Rats | Benzothiadiazines - pharmacology | Animals | Dorsal Raphe Nucleus - metabolism | Microdialysis | Spermine - pharmacology | Receptors, AMPA - agonists | Dorsal Raphe Nucleus - drug effects | Prefrontal Cortex - secretion | Antidepressive Agents - administration & dosage | Serotonin - secretion | Benzothiadiazines - administration & dosage | Ketamine - pharmacology | Dihydro-beta-Erythroidine - administration & dosage | Receptors, AMPA - antagonists & inhibitors
Journal Article
Journal Article