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Organic Letters, ISSN 1523-7060, 06/2019, Volume 21, Issue 11, pp. 3891 - 3894
A new donor (D)-acceptor (A) type naphthalene-based oxazepine-containing fluorophore, OXN-1, is reported, which shows unusually high stability in various... 
CHEMISTRY, ORGANIC | CELLS | BENZOXAZEPINE
Journal Article
Organic Letters, ISSN 1523-7060, 05/2017, Volume 19, Issue 9, pp. 2370 - 2373
An efficient and regioselective synthesis of novel 1,2,3-triazole-fused-1,5-benzoxazocinones through intramolecular cyclization of substituted ethynyl triazoyl... 
ONE-POT | 1,3-DIPOLAR CYCLOADDITION | ALKYLIDENE LACTONES | CHEMISTRY, ORGANIC | BENZODIAZEPINE | ORGANIC AZIDES | ALKYNES | DERIVATIVES | CYCLIZATION | BENZOXAZEPINE | CARBOXYLIC-ACIDS
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 03/2016, Volume 22, Issue 11, pp. 3891 - 3891
The search for efficient fluorination methods, which ideally help to unlock new reactivities, is fueled by the importance of fluorinated molecules. With the... 
hypervalent iodine | fluorination | benzoxazepines | 1,2-aryl shift
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 5, pp. 1892 - 1896
Expansion of the 6-membered ring and subsequent fine-tuning of the newly obtained 7-membered spiropiperidine structure resulted in the discovery of a series of... 
SCD1 inhibitor | Spiropiperidine | Pyridazine | Benzoxazepine
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 12/2018, Volume 83, Issue 23, pp. 14802 - 14810
A practical copper-catalyzed multicomponent reaction has been developed for the synthesis of 1H-[1,2,3]­triazolo­[4,5-c]­quinoline derivatives from... 
TANDEM REACTIONS | CASCADE REACTIONS | DIRECT AMINATION | ONE-POT SYNTHESIS | C-N | CLICK CHEMISTRY | 1,3-DIPOLAR CYCLOADDITION | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | SELECTIVE SYNTHESIS | TRIAZOLO-BENZOXAZEPINE
Journal Article
ORGANIC PROCESS RESEARCH & DEVELOPMENT, ISSN 1083-6160, 05/2019, Volume 23, Issue 5, pp. 775 - 782
Two convergent regioselective routes for the synthesis of the tetracyclic imidazobenzoxazepine triazole 1, a key intermediate toward the synthesis of... 
1,2,4-triazole | benzoxazepine | RING HYDROGENS | CHEMISTRY, ORGANIC | Negishi coupling | amidine | HETEROAROMATIC SYSTEMS | 1,2,4-TRIAZOLES | CHEMISTRY, APPLIED | ISOTOPE-EXCHANGE | alpha-chloro ketone
Journal Article
ARKIVOC, ISSN 1551-7004, 2019, pp. 142 - 151
A versatile and transition metal-free approach for the synthesis of a series of the novel 2,3,5,6-tetrahydro-11bH-[1,3]oxazolo[3,2-d][1,4]benzoxazepines,... 
[1,4]benzoxazepine | CHEMISTRY, ORGANIC | 1,3-oxazinane | hexahydropyrimidine | 2-(2-bromoethoxy) benzaldehyde | HYDROAMINATION | INHIBITORS | 1,3-oxazolidine
Journal Article
Nano Biomedicine and Engineering, ISSN 2150-5578, 2018, Volume 10, Issue 2, pp. 129 - 140
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2015, Volume 71, Issue 39, pp. 7332 - 7338
Two new ring systems, isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine, were conveniently synthesized through cyclization of suitably substituted... 
Isoindolo[1,4]benzoxazinone | Isoindolo[1,5]benzoxazepine | Antiproliferative activity | Isoindole | POTENT | ANALOGS | JL13 | CHEMISTRY, ORGANIC | AGENTS | ANTITUMOR-ACTIVITY | DERIVATIVES | MARINE ALKALOID NORTOPSENTIN
Journal Article
Organic Process Research and Development, ISSN 1083-6160, 2019, Volume 23, Issue 5, pp. 783 - 793
A highly efficient and regioselective manufacturing route for the phosphoinositide 3-kinase beta-sparing inhibitor taselisib was developed. Highlights of the... 
benzoxazepine | amidine | late-stage development | 1,2,4-triazole | Miyaura borylation | Suzuki-Miyaura cross-coupling | PALLADIUM | CONVERSION | SCOPE | CHEMISTRY, ORGANIC | DISCOVERY | CROSS-COUPLING REACTIONS | NITRILES | CHEMISTRY, APPLIED
Journal Article
Chemistry of Heterocyclic Compounds, ISSN 0009-3122, 5/2016, Volume 52, Issue 5, pp. 326 - 330
An efficient and practical method has been developed for the synthesis of 6-aryl-substituted pyrido[2,3-b][1,4]benzoxazepines via a Friedel−Crafts reaction of... 
Chemistry | tricyclic compounds | Friedel−Crafts cyclization | Pharmacy | 2-phenoxypyridin-3-amine | pyrido[2,3- b ][1,4]benzoxazepine | Organic Chemistry | pyrido[2,3-b][1,4]benzoxazepine | Friedel-Crafts cyclization | Pyrido[2,3-b][1,4]benzoxazepine | Tricyclic compounds | CHEMISTRY, ORGANIC | Substitution reactions | Drug discovery
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 01/2013
A new series of pyrazole, isoxazole, benzoxazepine, benzothiazepine and benzodiazepine derivatives were prepared by the multi-component cyclo-condensation... 
Isoxazole | Anti-inflammatory | Pyrazole | Benzodiazepine | Benzothiazepine | Benzoxazepine
Journal Article
Molecular Diversity, ISSN 1381-1991, 05/2016, Volume 20, Issue 2, pp. 483 - 495
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2017, Volume 23, Issue 57, p. n/a
Modular access to a range of tailored heterocyclic scaffolds with diverse 3D‐complexity is provided by a novel cascade one‐pot methodology based on... 
benzoxazepines | Pictet–Spengler reaction | diversity oriented synthesis | aza-Michael addition | stereoselective synthesis
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 07/2017, Volume 54, Issue 4, pp. 2393 - 2396
A versatile and transition metal‐free approach for the synthesis of new 7‐methylene‐6,7‐dihyrobenzo[f]benzo[4,5]imidazo[1,2‐d][1,4]oxazepines were developed by... 
ALKENES | AMINES | CHEMISTRY, ORGANIC | OLEFINS | AGENTS | BENZOXAZEPINE DERIVATIVES | ALKYNES | PHARMACOLOGICAL EVALUATION | EFFICIENT | Carbonates
Journal Article
Synthesis, ISSN 0039-7881, 09/2019, Volume 51, Issue 18, pp. 3485 - 3490
Abstract The reaction between N -tosyl- N -[6-(2-cyclopenten-1-yl)phenyl]glycine ( syn / anti atropisomeric mixture) and molecular iodine is studied. Along... 
paper | atropisomers | X-ray crystal structure analysis | RING-CLOSING METATHESIS | glycine | CHEMISTRY, ORGANIC | benzoxazepines | halolactonization | BENZOXAZOCINES | DERIVATIVES | DISCOVERY
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 04/2017, Volume 58, Issue 16, pp. 1640 - 1643
A series of compounds containing the benzoxazepine-isoquinoline scaffold was synthesized in a one-pot procedure via an Ugi reaction followed by tautomerization... 
Isoquinoline | Multicomponent reaction | Nucleophilic substitution reaction | One-pot operation | Benzoxazepine | ENTRY | ONE-POT | ARYLATION | UDC STRATEGY | CHEMISTRY, ORGANIC | MULTICOMPONENT REACTIONS | CHEMISTRY | INHIBITORS | SCAFFOLDS | FACILE | WATER | Alkaloids | Synthesis | Organic compounds
Journal Article
Journal of the Chilean Chemical Society, ISSN 0717-9324, 2018, Volume 63, Issue 2, pp. 3983 - 3987
In the present study a series of novel benzoxazepine (5a-h) derivatives were synthesized by the thermal cyclization reaction of various pyrazole-chalcones... 
Microwave irradiation | Basic alumina | Chalcone | Pyrazole | Benzoxazepine | ASSISTED SYNTHESIS | CELLS | MICROWAVE | JL13 | benzoxazepine | CHEMISTRY, MULTIDISCIPLINARY | ANTIOXIDANT | microwave irradiation | AGENTS | basic alumina | ANTIMICROBIAL ACTIVITY
Journal Article
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