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Journal of Immunology, ISSN 0022-1767, 06/2011, Volume 186, Issue 11, pp. 6553 - 6561
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2016, Volume 22, Issue 9, pp. 1002 - 1012
Altered metabolism has been implicated in the pathogenesis of inflammatory diseases. NADPH oxidase 4 (NOX4), a source of cellular superoxide anions, has... 
MEDICINE, RESEARCH & EXPERIMENTAL | CARNITINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PALMITOYLTRANSFERASE-I | CELL BIOLOGY | DIABETES-MELLITUS | NAD(P)H OXIDASE | METABOLISM | INSULIN-RESISTANCE | DISEASE | NOX4 | BETA-CELL | STRESS | Benzoxazoles - pharmacology | Metabolomics | Carnitine O-Palmitoyltransferase - genetics | Humans | Immunoblotting | Lipid Metabolism - immunology | DNA-Binding Proteins - metabolism | Calcium-Binding Proteins - immunology | Carnitine O-Palmitoyltransferase - metabolism | Adaptor Proteins, Signal Transducing - immunology | NADPH Oxidases - genetics | Fatty Acids - metabolism | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Cytokines - immunology | Pyrazoles - pharmacology | Calcium-Binding Proteins - metabolism | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Oxidation-Reduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | NADPH Oxidases - antagonists & inhibitors | NADPH Oxidase 4 | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Streptococcus pneumoniae | Triazoles - pharmacology | Macrophages - metabolism | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Inflammasomes - immunology | Lipid Metabolism - drug effects | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Pyridines - pharmacology | Streptococcal Infections - immunology | Adaptor Proteins, Signal Transducing - metabolism | Oxidases | Transferases | Cellular signal transduction | Genetic aspects | Properties | Enzyme activation | Health aspects | Oxidation | Metabolism | Fatty acids | Cells
Journal Article
Diabetes, ISSN 0012-1797, 01/2015, Volume 64, Issue 1, pp. 226 - 235
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 01/2016, Volume 94, Issue 1, pp. 15 - 26
Alzheimer's disease (AD) is the most common type of dementia among the elderly. Neurofibrillary tangles (NFTs), a major pathological hallmark of AD, are... 
WAVE1 | tau | ATRA | Alzheimer's disease | CRMP2 | neurofibrillary tangle | Tau | Neurofibrillary tangle | NEUROFIBRILLARY TANGLES | RESPONSE MEDIATOR PROTEIN-2 | ACTIN POLYMERIZATION | DYSTROPHIC NEURITES | NEUROSCIENCES | MOUSE MODEL | IN-VIVO | A-BETA | NEURONS | CYCLIN-DEPENDENT KINASE-5 | BRAIN | Phosphorylation - physiology | Aniline Compounds - metabolism | Humans | Benzoxazoles - metabolism | tau Proteins - metabolism | Hippocampus - drug effects | Glial Fibrillary Acidic Protein - metabolism | Alzheimer Disease - pathology | Intercellular Signaling Peptides and Proteins - metabolism | tau Proteins - genetics | Antipsychotic Agents - therapeutic use | Microfilament Proteins - metabolism | Neurons - metabolism | Calcium-Binding Proteins - metabolism | Wiskott-Aldrich Syndrome Protein Family - metabolism | Gene Expression Regulation - genetics | Alzheimer Disease - drug therapy | Presenilin-1 - genetics | Mice, Transgenic | Hippocampus - pathology | Neurites - metabolism | Cyclin-Dependent Kinase 5 - metabolism | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Neurites - pathology | Amyloid beta-Protein Precursor - genetics | Animals | Tretinoin - therapeutic use | Alzheimer Disease - metabolism | Mice | Alzheimer Disease - genetics | Proteins | Genetic engineering | Synthesis | Glycogen | Analysis
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7396, pp. 55 - 61
The mammalian target of rapamycin (mTOR) kinase is a master regulator of protein synthesis that couples nutrient sensing to cell growth and cancer. However,... 
RAPAMYCIN | STEM-CELLS | COMPLEX | PHOSPHORYLATION | PATHWAY | TOP MESSENGER-RNAS | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | IN-VIVO | PROTEIN-SYNTHESIS | PROMOTES | Benzoxazoles - pharmacology | Protein Biosynthesis | TOR Serine-Threonine Kinases - metabolism | Humans | Genome - genetics | Eukaryotic Initiation Factor-4E - metabolism | Male | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Cell Movement - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Prostatic Neoplasms - genetics | Neoplasm Metastasis - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Prostatic Neoplasms - drug therapy | Repressor Proteins - metabolism | Eukaryotic Initiation Factors - metabolism | Prostatic Neoplasms - pathology | Signal Transduction | Mice, Inbred C57BL | RNA, Messenger - genetics | Pyrimidines - pharmacology | Cell Movement - drug effects | Neoplasm Metastasis - genetics | Animals | Cell Line, Tumor | Mice | Adaptor Proteins, Signal Transducing - metabolism | Neoplasm Invasiveness - genetics | Physiological aspects | Rapamycin | Genetic aspects | Research | Metastasis | Genetic translation | Health aspects | Cancer | Phosphorylation | Protein synthesis | Rodents | Genomes | Kinases | Gene expression | Prostate cancer
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2014, Volume 130, Issue 4, pp. 526 - 540
Journal Article
Biochimica et biophysica acta, ISSN 0006-3002, 12/2016, Volume 1863, Issue 12, p. 3096
Differentiation of embryonic stem (ES) cells may be regulated by mechanical strain. Herein, signaling molecules underlying mechanical stimulation of... 
Benzoxazoles - pharmacology | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Calcium - metabolism | Embryo, Mammalian | Neuropilin-1 - metabolism | Mouse Embryonic Stem Cells - cytology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Mouse Embryonic Stem Cells - drug effects | Reactive Oxygen Species - agonists | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Cell Differentiation | Semaphorins - genetics | Fibroblasts - metabolism | Calcium - agonists | Signal Transduction | Semaphorins - metabolism | Ephrin-B2 - metabolism | Embryoid Bodies - drug effects | Ephrin-B2 - genetics | Biomechanical Phenomena | Myocytes, Cardiac - drug effects | Fibroblast Growth Factor 2 - genetics | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Receptors, Immunologic - genetics | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Neuropilin-1 - genetics | Neovascularization, Physiologic - drug effects | Mouse Embryonic Stem Cells - metabolism | Neuropilin-1 - antagonists & inhibitors | Receptor, EphB4 - genetics | Ephrin-B2 - antagonists & inhibitors | Egtazic Acid - analogs & derivatives | Fibroblast Growth Factor 2 - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-sis - genetics | Myocytes, Cardiac - cytology | Proto-Oncogene Proteins c-sis - metabolism | Neovascularization, Physiologic - genetics | Gene Expression Regulation | Receptors, Cell Surface - metabolism | Nerve Tissue Proteins - genetics | Receptor, EphB4 - metabolism | Nitric Oxide - agonists | Nerve Tissue Proteins - metabolism | Triazoles - pharmacology | Animals | Egtazic Acid - pharmacology | Nitric Oxide - metabolism | Receptors, Immunologic - metabolism
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2010, Volume 298, Issue 6, pp. 1457 - 1468
TRPA1 is a nonselective cation channel belonging to the transient receptor potential (TRP) family that is expressed in peripheral sensory neurons and may play... 
Gap junction proteins | Sensory neurons | Pain | Pannexins | Transient receptor potential channels | CELLS | pain | ACTIVATION | PHYSIOLOGY | ION-CHANNEL TRPA1 | CALCIUM-IONS | ACID | pannexins | FLEXIBILITY | transient receptor potential channels | gap junction proteins | sensory neurons | TRPV1 | CELL BIOLOGY | INHIBITION | P2X RECEPTOR | COVALENT MODIFICATION | Meglumine - metabolism | Calcium Channels - metabolism | Cricetulus | Calcium - metabolism | Farnesol - pharmacology | Humans | Benzoxazoles - metabolism | Dose-Response Relationship, Drug | Salicylates - pharmacology | TRPV Cation Channels - metabolism | Transfection | Membrane Transport Modulators - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | Transient Receptor Potential Channels - metabolism | Calcium Channels - genetics | Cell Membrane - drug effects | Isothiocyanates - pharmacology | CHO Cells | Carbamates - pharmacology | Quinolinium Compounds - metabolism | Cricetinae | Nerve Tissue Proteins - agonists | TRPV Cation Channels - agonists | Rats | TRPM Cation Channels - agonists | Purinergic P2 Receptor Agonists | Nerve Tissue Proteins - genetics | Transient Receptor Potential Channels - agonists | Nerve Tissue Proteins - metabolism | Receptors, Purinergic P2X7 | Animals | Transient Receptor Potential Channels - genetics | Cell Membrane Permeability - drug effects | Receptors, Purinergic P2 - metabolism | TRPA1 Cation Channel | Dogs | Farnesol - analogs & derivatives | TRPM Cation Channels - metabolism | Kinetics | Ion Channel Gating - drug effects | Physiological aspects | Sensory receptors | Ion channels | Properties
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2012, Volume 18, Issue 9, pp. 2603 - 2612
Journal Article
Neurotoxicity Research, ISSN 1029-8428, 05/2018, Volume 33, Issue 4, pp. 768 - 780
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2018, Volume 838, pp. 78 - 84
Journal Article