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The Journal of immunology (1950), ISSN 1550-6606, 06/2011, Volume 186, Issue 11, pp. 6553 - 6561
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 06/2010, Volume 298, Issue 6, pp. 1457 - 1468
TRPA1 is a nonselective cation channel belonging to the transient receptor potential (TRP) family that is expressed in peripheral sensory neurons and may play... 
Gap junction proteins | Sensory neurons | Pain | Pannexins | Transient receptor potential channels | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Meglumine - metabolism | Calcium Channels - metabolism | Cricetulus | Calcium - metabolism | Farnesol - pharmacology | Humans | Benzoxazoles - metabolism | Dose-Response Relationship, Drug | Salicylates - pharmacology | TRPV Cation Channels - metabolism | Transfection | Membrane Transport Modulators - pharmacology | Benzamides - pharmacology | Cell Membrane - metabolism | Transient Receptor Potential Channels - metabolism | Calcium Channels - genetics | Cell Membrane - drug effects | Isothiocyanates - pharmacology | CHO Cells | Carbamates - pharmacology | Quinolinium Compounds - metabolism | Cricetinae | Nerve Tissue Proteins - agonists | TRPV Cation Channels - agonists | Rats | TRPM Cation Channels - agonists | Purinergic P2 Receptor Agonists | Nerve Tissue Proteins - genetics | Transient Receptor Potential Channels - agonists | Nerve Tissue Proteins - metabolism | Receptors, Purinergic P2X7 | Animals | Transient Receptor Potential Channels - genetics | Cell Membrane Permeability - drug effects | Receptors, Purinergic P2 - metabolism | TRPA1 Cation Channel | Dogs | Farnesol - analogs & derivatives | TRPM Cation Channels - metabolism | Kinetics | Ion Channel Gating - drug effects | Physiological aspects | Sensory receptors | Ion channels | Properties | Proteins | Sensory perception | Gene expression | Neurons | Index Medicus
Journal Article
Nature medicine, ISSN 1546-170X, 07/2016, Volume 22, Issue 9, pp. 1002 - 1012
Altered metabolism has been implicated in the pathogenesis of inflammatory diseases... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Benzoxazoles - pharmacology | Metabolomics | Carnitine O-Palmitoyltransferase - genetics | Humans | Immunoblotting | Lipid Metabolism - immunology | DNA-Binding Proteins - metabolism | Calcium-Binding Proteins - immunology | Carnitine O-Palmitoyltransferase - metabolism | Adaptor Proteins, Signal Transducing - immunology | NADPH Oxidases - genetics | Fatty Acids - metabolism | Real-Time Polymerase Chain Reaction | Macrophages - immunology | Cytokines - immunology | Pyrazoles - pharmacology | Calcium-Binding Proteins - metabolism | Apoptosis Regulatory Proteins - immunology | DNA-Binding Proteins - immunology | Oxidation-Reduction | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | NADPH Oxidases - antagonists & inhibitors | NADPH Oxidase 4 | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Streptococcus pneumoniae | Triazoles - pharmacology | Macrophages - metabolism | Animals | NLR Family, Pyrin Domain-Containing 3 Protein - immunology | Inflammasomes - immunology | Lipid Metabolism - drug effects | Lipopolysaccharides - pharmacology | Macrophages - drug effects | Mice | Pyridines - pharmacology | Streptococcal Infections - immunology | Adaptor Proteins, Signal Transducing - metabolism | Oxidases | Transferases | Cellular signal transduction | Genetic aspects | Properties | Enzyme activation | Health aspects | Oxidation | Metabolism | Fatty acids | Cells | Index Medicus
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 02/2010, Volume 30, Issue 6, pp. 2300 - 2310
Emerging evidence suggests that the hypocretinergic system is involved in addictive behavior. In this study, we investigated the role of these hypothalamic... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Benzoxazoles - pharmacology | Nicotine - administration & dosage | Male | Neuropeptides - physiology | Behavior, Addictive - metabolism | Paraventricular Hypothalamic Nucleus - physiopathology | Tobacco Use Disorder - metabolism | Nicotine - pharmacology | Self Administration | Conditioning, Operant - drug effects | Urea - analogs & derivatives | Tobacco Use Disorder - psychology | Neurons - metabolism | Neuropeptides - genetics | Behavior, Addictive - physiopathology | Anxiety - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Orexins | Mice, Inbred C57BL | Anxiety - psychology | Receptors, Neuropeptide - antagonists & inhibitors | Anxiety - physiopathology | Tobacco Use Disorder - physiopathology | Orexin Receptors | Pyrimidines - pharmacology | Corticotropin-Releasing Hormone - metabolism | Mice, Knockout | Paraventricular Hypothalamic Nucleus - drug effects | Pyrroles - pharmacology | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Arginine Vasopressin - metabolism | Extinction, Psychological | Paraventricular Hypothalamic Nucleus - metabolism | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice | Behavior, Addictive - psychology | Intracellular Signaling Peptides and Proteins - physiology | Urea - pharmacology | Index Medicus | Addicció | Efectes fisiològics | Nicotina
Journal Article
Biochimica et biophysica acta. Molecular cell research, ISSN 0167-4889, 12/2016, Volume 1863, Issue 12, pp. 3096 - 3105
Differentiation of embryonic stem (ES) cells may be regulated by mechanical strain. Herein, signaling molecules underlying mechanical stimulation of... 
Reactive oxygen species | Vasculogenesis | Intracellular calcium | Embryonic stem cells | Mechanical strain | Nitric oxide | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Benzoxazoles - pharmacology | RNA, Small Interfering - genetics | Reactive Oxygen Species - metabolism | Calcium - metabolism | Embryo, Mammalian | Neuropilin-1 - metabolism | Mouse Embryonic Stem Cells - cytology | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Mouse Embryonic Stem Cells - drug effects | Reactive Oxygen Species - agonists | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Embryoid Bodies - metabolism | Embryoid Bodies - cytology | Cell Differentiation | Semaphorins - genetics | Fibroblasts - metabolism | Calcium - agonists | Signal Transduction | Semaphorins - metabolism | Ephrin-B2 - metabolism | Embryoid Bodies - drug effects | Ephrin-B2 - genetics | Biomechanical Phenomena | Myocytes, Cardiac - drug effects | Fibroblast Growth Factor 2 - genetics | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - cytology | Mice | Receptors, Immunologic - genetics | RNA, Small Interfering - metabolism | Receptors, Cell Surface - genetics | Neuropilin-1 - genetics | Neovascularization, Physiologic - drug effects | Mouse Embryonic Stem Cells - metabolism | Neuropilin-1 - antagonists & inhibitors | Receptor, EphB4 - genetics | Ephrin-B2 - antagonists & inhibitors | Egtazic Acid - analogs & derivatives | Fibroblast Growth Factor 2 - metabolism | NG-Nitroarginine Methyl Ester - pharmacology | Nerve Tissue Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-sis - genetics | Myocytes, Cardiac - cytology | Proto-Oncogene Proteins c-sis - metabolism | Neovascularization, Physiologic - genetics | Gene Expression Regulation | Receptors, Cell Surface - metabolism | Nerve Tissue Proteins - genetics | Receptor, EphB4 - metabolism | Nitric Oxide - agonists | Nerve Tissue Proteins - metabolism | Triazoles - pharmacology | Animals | Egtazic Acid - pharmacology | Nitric Oxide - metabolism | Receptors, Immunologic - metabolism
Journal Article
Nature (London), ISSN 1476-4687, 02/2012, Volume 485, Issue 7396, pp. 55 - 61
... proliferation, metabolism and invasion. We extend these findings by functionally characterizing a class of translationally controlled pro-invasion messenger RNAs that we show direct prostate cancer invasion and metastasis downstream... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Benzoxazoles - pharmacology | Protein Biosynthesis | TOR Serine-Threonine Kinases - metabolism | Humans | Genome - genetics | Eukaryotic Initiation Factor-4E - metabolism | Male | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Cell Movement - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Prostatic Neoplasms - genetics | Neoplasm Metastasis - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Prostatic Neoplasms - drug therapy | Repressor Proteins - metabolism | Eukaryotic Initiation Factors - metabolism | Prostatic Neoplasms - pathology | Signal Transduction | Mice, Inbred C57BL | RNA, Messenger - genetics | Pyrimidines - pharmacology | Cell Movement - drug effects | Neoplasm Metastasis - genetics | Animals | Cell Line, Tumor | Mice | Adaptor Proteins, Signal Transducing - metabolism | Neoplasm Invasiveness - genetics | Physiological aspects | Rapamycin | Genetic aspects | Research | Metastasis | Genetic translation | Health aspects | Cancer | Phosphorylation | Protein synthesis | Rodents | Genomes | Kinases | Gene expression | Prostate cancer | Index Medicus
Journal Article
Psychopharmacology (Berlin, Germany), ISSN 1432-2072, 03/2012, Volume 226, Issue 4, pp. 687 - 698
Glutamate and orexin/hypocretin systems are involved in Pavlovian cue-triggered drug seeking.Here, we asked whether orexin and glutamate interact within... 
Self-administration | Neurosciences | Relapse | AMPA | Glutamate | Hypocretin | Biomedicine | Addiction | Conditioned | NMDA | Cocaine | Pharmacology/Toxicology | Psychiatry | Ventral tegmental area | Pharmacology & Pharmacy | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Benzoxazoles - pharmacology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Receptors, G-Protein-Coupled - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Receptors, Neuropeptide - drug effects | Male | Receptors, Neuropeptide - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Dose-Response Relationship, Drug | Drug-Seeking Behavior | Self Administration | Urea - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, G-Protein-Coupled - drug effects | Cues | Orexins | Signal Transduction | Rats | Neuropeptides - metabolism | Orexin Receptors | Rats, Sprague-Dawley | 6-Cyano-7-nitroquinoxaline-2,3-dione - administration & dosage | Cocaine - administration & dosage | Animals | Ventral Tegmental Area - metabolism | 2-Amino-5-phosphonovalerate - administration & dosage | Glutamic Acid - metabolism | Urea - pharmacology | Receptors, AMPA - antagonists & inhibitors | Brain | Neurotransmitters | Animal behavior | Rodents | Addictive behaviors | Index Medicus
Journal Article
International journal of molecular medicine, ISSN 1107-3756, 2014, Volume 34, Issue 1, pp. 153 - 159
Orexin A and B are multifunctional neuropeptides that are involved in the regulation of food intake, energy metabolism, glucose regulation and wakefulness... 
Forkhead box O1 | Mammalian target of rapamycin 1 | Orexin A | Orexin receptor 1 | Cell apoptosis | PI3K/AKT | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Benzoxazoles - pharmacology | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Male | Multiprotein Complexes - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Multiprotein Complexes - metabolism | TOR Serine-Threonine Kinases - genetics | Forkhead Transcription Factors - metabolism | Neuropeptides - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Everolimus | Intracellular Signaling Peptides and Proteins - genetics | Orexin Receptor Antagonists | Rats | Neuropeptides - metabolism | Pyrimidines - pharmacology | Rats, Sprague-Dawley | Signal Transduction - drug effects | Urea - pharmacology | Intracellular Signaling Peptides and Proteins - pharmacology | Culture Media, Serum-Free | Phosphatidylinositol 3-Kinases - metabolism | Quinolones - pharmacology | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | Dose-Response Relationship, Drug | TOR Serine-Threonine Kinases - antagonists & inhibitors | Hepatocytes - cytology | Urea - analogs & derivatives | Orexin Receptors - genetics | Forkhead Transcription Factors - antagonists & inhibitors | Neuropeptides - genetics | Hepatocytes - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Orexin Receptors - metabolism | Sirolimus - analogs & derivatives | Orexins | Gene Expression Regulation | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Sirolimus - pharmacology | Nerve Tissue Proteins - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Primary Cell Culture | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Pyridones - pharmacology
Journal Article