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benzylidene compounds - chemistry (251) 251
benzylidene compounds - pharmacology (230) 230
science & technology (225) 225
benzylidene compounds - chemical synthesis (212) 212
animals (177) 177
humans (167) 167
chemistry (162) 162
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structure-activity relationship (119) 119
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male (65) 65
rats (63) 63
chemistry, medicinal (60) 60
stereoisomerism (60) 60
organic chemistry (58) 58
antineoplastic agents - chemical synthesis (57) 57
analysis (56) 56
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models, molecular (51) 51
biochemistry & molecular biology (50) 50
dose-response relationship, drug (50) 50
female (48) 48
exact sciences and technology (45) 45
chemistry, organic (44) 44
cell proliferation - drug effects (39) 39
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catalysis (37) 37
chemistry, multidisciplinary (37) 37
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synthesis (37) 37
microbial sensitivity tests (33) 33
molecular conformation (33) 33
drug design (32) 32
cancer (30) 30
drug screening assays, antitumor (30) 30
glycosylation (30) 30
preparations and properties (30) 30
apoptosis - drug effects (29) 29
enzyme inhibitors - pharmacology (29) 29
general aspects (29) 29
cell survival - drug effects (28) 28
crystallography, x-ray (28) 28
piperidones - pharmacology (27) 27
cell biology (26) 26
inhibitory concentration 50 (25) 25
apoptosis (24) 24
benzylidene compounds - therapeutic use (24) 24
chemical properties (24) 24
molecular docking simulation (24) 24
antibiotics. antiinfectious agents. antiparasitic agents (23) 23
chemical phenomena (23) 23
enzyme inhibitors - chemical synthesis (23) 23
heterocyclic compounds (23) 23
ligands (22) 22
oncology (22) 22
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cell line (21) 21
cytotoxicity (21) 21
drug discovery (19) 19
enzyme inhibitors - chemistry (19) 19
proteins (19) 19
research (19) 19
technology (19) 19
oxidation-reduction (18) 18
benzylidene (17) 17
signal transduction - drug effects (17) 17
anti-bacterial agents - pharmacology (16) 16
benzylidene compounds - metabolism (16) 16
binding sites (16) 16
chemistry, physical (16) 16
aniline compounds - pharmacology (15) 15
anti-bacterial agents - chemical synthesis (15) 15
bacteria - drug effects (15) 15
benzylidene compounds (15) 15
care and treatment (15) 15
chemical synthesis (15) 15
hydrazines - chemical synthesis (15) 15
medicine (15) 15
phosphorylation (15) 15
physical chemistry (15) 15
science & technology - other topics (15) 15
applied sciences (14) 14
chemical compounds (14) 14
cyclization (14) 14
fungi - drug effects (14) 14
hela cells (14) 14
hydrazines - pharmacology (14) 14
hydrogen bonding (14) 14
inorganic chemistry (14) 14
research article (14) 14
structure (14) 14
acetals - chemistry (13) 13
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1. Full Text The discovery of oxazolones-grafted spirooxindoles via three-component diversity oriented synthesis and their preliminary biological evaluation
by Dong, Hui and Song, Sicheng and Li, Jingjing and Xu, Chunyun and Zhang, Haowei and Ouyang, Liang
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 09/2015, Volume 25, Issue 17, pp. 3585 - 3591
1,3-Dipolar cycloaddition | Spirooxindole derivatives | Multi-component reactions | Azomethine ylides | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Indoles - chemical synthesis | Benzylidene Compounds - chemistry | Pyrrolidines - pharmacology | Azo Compounds - chemistry | Thiosemicarbazones - chemistry | Spiro Compounds - chemical synthesis | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Thiosemicarbazones - pharmacology | Azo Compounds - pharmacology | Spiro Compounds - chemistry | Models, Molecular | Thiosemicarbazones - chemical synthesis | Azo Compounds - chemical synthesis | Oxazolone - chemistry | Benzylidene Compounds - chemical synthesis | Antineoplastic Agents - chemistry | Cycloaddition Reaction | Drug Discovery | Pyrrolidines - chemistry | Neoplasms - drug therapy | Oxazolone - analogs & derivatives | Benzylidene Compounds - pharmacology | Oxazolone - chemical synthesis | Pyrrolidines - chemical synthesis | Cell Line, Tumor | Indoles - chemistry | Oxazolone - pharmacology | Spiro Compounds - pharmacology | Index Medicus
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2. Full Text One-Step Synthesis of Isocoumarins and 3‑Benzylidenephthalides via Ligandless Pd-Catalyzed Oxidative Coupling of Benzoic Acids and Vinylarenes
by Nandi, Debkumar and Ghosh, Debalina and Chen, Shih-Ji and Kuo, Bing-Chiuan and Wang, Nancy M and Lee, Hon Man
Journal of organic chemistry, ISSN 0022-3263, 04/2013, Volume 78, Issue 7, pp. 3445 - 3451
Vinyl Compounds - chemistry | Oxidation-Reduction | Benzoates - chemistry | Isocoumarins - chemical synthesis | Ligands | Organometallic Compounds - chemistry | Benzylidene Compounds - chemical synthesis | Molecular Structure | Catalysis | Benzylidene Compounds - chemistry | Isocoumarins - chemistry | Palladium - chemistry | Thermal properties | Analysis | Oxidation-reduction reaction | Palladium | Chemical properties | Hydrogen bonding | Index Medicus
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3. Full Text Synthesis of α‑Arylated Cycloalkanones from Congested Trisubstituted Spiro-epoxides: Application of the House–Meinwald Rearrangement for Ring Expansion
by Jeedimalla, Nagalakshmi and Jacquet, Camille and Bahneva, Diana and Youte Tendoung, Jean-Jacques and Roche, Stéphane P
Journal of organic chemistry, ISSN 0022-3263, 10/2018, Volume 83, Issue 20, pp. 12357 - 12373
Styrenes - chemistry | Oxidation-Reduction | Ketones - chemical synthesis | Stereoisomerism | Epoxy Compounds - chemistry | Spiro Compounds - chemical synthesis | Cycloparaffins - chemical synthesis | Molecular Structure | Catalysis | Benzylidene Compounds - chemistry | Palladium - chemistry | Index Medicus
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4. Full Text Synthesis, crystal structures, and urease inhibition of an acetohydroxamate-coordinated oxovanadium(V) complex derived from N′-(3-bromo-2-hydroxybenzylidene)-4-methoxybenzohydrazide
by Qu, Dan and Niu, Fang and Zhao, Xinlu and Yan, Ke-Xiang and Ye, Yu-Ting and Wang, Jia and Zhang, Mei and You, Zhonglu
Bioorganic & medicinal chemistry, ISSN 0968-0896, 05/2015, Volume 23, Issue 9, pp. 1944 - 1949
Urease inhibition | Oxovanadium(V) complex | Benzohydrazone | Crystal structure | Enzyme Inhibitors - pharmacology | Hydroxamic Acids - chemistry | Models, Molecular | Crystallography, X-Ray | Structure-Activity Relationship | Urease - antagonists & inhibitors | Enzyme Inhibitors - chemical synthesis | Vanadates - chemistry | Benzylidene Compounds - chemistry | Hydrazones - chemistry | Dose-Response Relationship, Drug | Helicobacter pylori - enzymology | Organometallic Compounds - chemical synthesis | Enzyme Inhibitors - chemistry | Vanadates - pharmacology | Organometallic Compounds - chemistry | Urease - metabolism | Molecular Structure | Hydroxamic Acids - pharmacology | Organometallic Compounds - pharmacology | Enzymes | Hydrolases | Structure | Crystals | Index Medicus
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5. Full Text Synthesis, spectroscopic, X-ray crystal structure, biological and DNA interaction studies of organotin(IV) complexes of 2-(4-ethoxybenzylidene) butanoic acid
by Tariq, Muhammad and Muhammad, Niaz and Ali, Saqib and Shirazi, Jafir Hussain and Tahir, Muhammad Nawaz and Khalid, Nasir
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, ISSN 1386-1425, 03/2014, Volume 122, pp. 356 - 364
Antitumor activity | Distannoxane | Antimicrobial activity | Cytotoxic activity | Spectroscopy | Technology | Science & Technology | Butyrates - metabolism | Organotin Compounds - chemistry | Organotin Compounds - metabolism | Anti-Infective Agents - pharmacology | Bacteria - drug effects | Benzylidene Compounds - metabolism | Organotin Compounds - toxicity | Crystallography, X-Ray | Male | Spectroscopy, Fourier Transform Infrared | Benzylidene Compounds - chemistry | Viscosity - drug effects | Butyric Acid - chemistry | Microbial Sensitivity Tests | Organotin Compounds - chemical synthesis | Anti-Infective Agents - chemistry | Fishes | Butyric Acid - toxicity | Antineoplastic Agents - pharmacology | Benzylidene Compounds - toxicity | Cell Death - drug effects | Antifungal Agents - pharmacology | Fungi - drug effects | Magnetic Resonance Spectroscopy | Benzylidene Compounds - chemical synthesis | DNA - metabolism | Butyric Acid - chemical synthesis | Butyrates - chemical synthesis | Artemia - drug effects | Animals | Butyric Acid - metabolism | Butyrates - chemistry | Butyrates - toxicity | Ligands | Plant Tumors | Genetic research | Tin compounds | Structure | Saturated fatty acids | DNA | Crystals
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6. Full Text Synthesis of the Marine Myxobacterial Antibiotic Enhygrolide A
by Muddala, Ramesh and Acosta, Jaime A. M and Barbosa, Luiz C. A and Boukouvalas, John
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 07/2017, Volume 80, Issue 7, pp. 2166 - 2169
Stereoisomerism | 4-Butyrolactone - pharmacology | 4-Butyrolactone - chemical synthesis | Benzylidene Compounds - chemical synthesis | Benzylidene Compounds - chemistry | Alkylation | Anti-Bacterial Agents - chemical synthesis | Marine Biology | Myxococcales - chemistry | Benzylidene Compounds - pharmacology | Anti-Bacterial Agents - chemistry | 4-Butyrolactone - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Structure | 4-Butyrolactone - analogs & derivatives | Catalysis | Aldehydes - chemistry | Index Medicus
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7. Full Text Synthesis, characterization, DNA interactions, DNA cleavage, radical scavenging activity, antibacterial, anti-proliferative and docking studies of new transition metal complexes
by Chennam, Kishan Prasad and Chennam, Kishan Prasad and Ravi, Mudavath and Ravi, Mudavath and Ushaiah, B and Ushaiah, B and Srinu, V and Srinu, V and Eslavath, Ravi Kumar and Eslavath, Ravi Kumar and Devi, Ch Sarala and Devi, Ch Sarala
Journal of fluorescence, ISSN 1053-0509, 1/2016, Volume 26, Issue 1, pp. 189 - 205
Biochemistry, general | Biotechnology | Docking studies | Analytical Chemistry | Biomedicine | DNA interactions | Anti- proliferative activity | Biophysics and Biological Physics | DNA nuclease activity | Anti-bacterial activity | Biomedicine general | Radical scavenging | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Chemistry, Physical | Science & Technology | Free Radical Scavengers - pharmacology | Free Radical Scavengers - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Structure-Activity Relationship | Benzylidene Compounds - chemistry | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Naphthyridines - chemical synthesis | MCF-7 Cells | Metals - chemistry | Cattle | Anti-Bacterial Agents - chemistry | Free Radical Scavengers - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Cell Survival - drug effects | Naphthyridines - chemistry | Spectrometry, Fluorescence | Benzylidene Compounds - chemical synthesis | Antineoplastic Agents - chemistry | Plasmids - metabolism | Anti-Bacterial Agents - chemical synthesis | DNA - chemistry | Animals | Benzylidene Compounds - pharmacology | Organometallic Compounds - chemical synthesis | Organometallic Compounds - chemistry | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Molecular Docking Simulation | HeLa Cells | Spectrophotometry | DNA Cleavage | Naphthyridines - pharmacology | Organometallic Compounds - pharmacology | Drug Screening Assays, Antitumor | Metals - pharmacology | Antioxidants | Transition metal compounds | DNA | Genetic research | Chemical properties | Cobalt | Antibacterial agents | Index Medicus
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8. Full Text 2-Heteroarylimino-5-benzylidene-4-thiazolidinones analogues of 2-thiazolylimino-5-benzylidene-4-thiazolidinones with antimicrobial activity: Synthesis and structure–activity relationship
by Vicini, Paola and Geronikaki, Athina and Incerti, Matteo and Zani, Franca and Dearden, John and Hewitt, Mark
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2008, Volume 16, Issue 7, pp. 3714 - 3724
DEREK | 4-Thiazolidinone derivatives | QSAR | Antibacterial activity/antifungal activity | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | General aspects | Pharmacology. Drug treatments | Antifungal agents | Biological and medical sciences | Medical sciences | Antibacterial agents | Antibiotics. Antiinfectious agents. Antiparasitic agents | Thiazolidines - chemical synthesis | Microbial Viability - drug effects | Benzylidene Compounds - chemical synthesis | Structure-Activity Relationship | Benzylidene Compounds - chemistry | Anti-Bacterial Agents - chemical synthesis | Benzylidene Compounds - pharmacology | Anti-Bacterial Agents - chemistry | Drug Design | Anti-Bacterial Agents - pharmacology | Molecular Structure | Thiazolidines - pharmacology | Thiazolidines - chemistry | Heterocyclic compounds | Pharmacy | Index Medicus
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9. Full Text Synthesis and primary cytotoxicity evaluation of new 5-benzylidene-2,4-thiazolidinedione derivatives
by Patil, Vijay and Tilekar, Kalpana and Mehendale-Munj, Sonali and Mohan, Rhea and Ramaa, C.S
European journal of medicinal chemistry, ISSN 0223-5234, 2010, Volume 45, Issue 10, pp. 4539 - 4544
Cytotoxicity | Sulforhodamine B assay | 5-benzylidene-2,4-thiazolidinediones | Knoevenagel condensation | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Antineoplastic Agents - chemical synthesis | Humans | Leukemia - drug therapy | Benzylidene Compounds - chemical synthesis | Thiazolidinediones - chemistry | Antineoplastic Agents - chemistry | Benzylidene Compounds - chemistry | Breast Neoplasms - drug therapy | Benzylidene Compounds - pharmacology | Thiazolidinediones - chemical synthesis | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Thiazolidinediones - pharmacology | Drug Screening Assays, Antitumor | Cell research | Analysis | Leukemia | Index Medicus
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10. Full Text Synthesis and Biological Evaluation of Novel 5-Benzylidenethiazolidine-2,4-dione Derivatives for the Treatment of Inflammatory Diseases
by Ma, Liang and Xie, Caifeng and Ma, Yinghua and Liu, Juan and Xiang, Mingli and Ye, Xia and Zheng, Hao and Chen, Zhizhi and Xu, Qinyuan and Chen, Tao and Chen, Jinying and Yang, Jincheng and Qiu, Neng and Wang, Guangcheng and Liang, Xiaolin and Peng, Aihua and Yang, Shengyong and Wei, Yuquan and Chen, Lijuan
Journal of medicinal chemistry, ISSN 0022-2623, 04/2011, Volume 54, Issue 7, pp. 2060 - 2068
Gene Expression Regulation, Enzymologic - drug effects | Arthritis, Experimental - drug therapy | Dinoprostone - biosynthesis | Humans | Nitric Oxide Synthase Type II - chemistry | Thiazolidinediones - toxicity | Male | Dose-Response Relationship, Drug | Inflammation - metabolism | Thiazolidinediones - therapeutic use | Inflammation - drug therapy | Carrageenan - pharmacology | Anti-Inflammatory Agents - therapeutic use | Inhibitory Concentration 50 | Female | Benzylidene Compounds - toxicity | Thiazolidinediones - pharmacology | Cell Line | Nitric Oxide - biosynthesis | Anti-Inflammatory Agents - pharmacology | Anti-Inflammatory Agents - toxicity | Models, Molecular | Rats | Benzylidene Compounds - chemical synthesis | Edema - drug therapy | Animals | Benzylidene Compounds - pharmacology | Thiazolidinediones - chemical synthesis | Benzylidene Compounds - therapeutic use | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Protein Conformation | Anti-Inflammatory Agents - chemical synthesis | Mice | Edema - chemically induced | Inflammation - enzymology | Nitric Oxide Synthase Type II - metabolism | Index Medicus
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11. Full Text Multitarget-Directed Benzylideneindanone Derivatives: Anti-β-Amyloid (Aβ) Aggregation, Antioxidant, Metal Chelation, and Monoamine Oxidase B (MAO-B) Inhibition Properties against Alzheimer’s Disease
by Huang, Ling and Lu, Chuanjun and Sun, Yang and Mao, Fei and Luo, Zonghua and Su, Tao and Jiang, Huailei and Shan, Wenjun and Li, Xingshu
Journal of medicinal chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 19, pp. 8483 - 8492
Antioxidants - chemistry | Humans | Isoenzymes - chemistry | Structure-Activity Relationship | Amyloid - chemistry | Monoamine Oxidase Inhibitors - chemical synthesis | Zinc - chemistry | Benzylidene Compounds - chemistry | Monoamine Oxidase - chemistry | Copper - chemistry | Indans - chemistry | Iron - chemistry | Chelating Agents - chemistry | Alzheimer Disease - drug therapy | Recombinant Proteins - chemistry | Benzylidene Compounds - chemical synthesis | Antioxidants - chemical synthesis | Peptide Fragments - chemistry | Cations, Divalent | Indans - chemical synthesis | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Amyloid beta-Peptides - chemistry | Chelating Agents - chemical synthesis | Isoenzymes - antagonists & inhibitors | Monoamine Oxidase - metabolism | Index Medicus
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12. Full Text Discovery of a Rhodanine Class of Compounds as Inhibitors of Plasmodium falciparum Enoyl-Acyl Carrier Protein Reductase
by Kumar, Gyanendra and Parasuraman, Prasanna and Sharma, Shailendra Kumar and Banerjee, Tanushree and Karmodiya, Krishanpal and Surolia, Namita and Surolia, Avadhesha
Journal of medicinal chemistry, ISSN 0022-2623, 05/2007, Volume 50, Issue 11, pp. 2665 - 2675
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Antiparasitic agents | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Plasmodium falciparum - enzymology | Quinazolines - chemical synthesis | Rhodanine - chemical synthesis | Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) - antagonists & inhibitors | Furans - pharmacology | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Quinolines - pharmacology | Rhodanine - analogs & derivatives | Rhodanine - pharmacology | Antimalarials - chemical synthesis | Drug Resistance | Models, Molecular | Benzylidene Compounds - chemical synthesis | Antimalarials - pharmacology | Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) - chemistry | Erythrocytes - drug effects | Triclosan - chemistry | Quinolines - chemical synthesis | Animals | Benzylidene Compounds - pharmacology | Furans - chemical synthesis | Kinetics | Erythrocytes - parasitology | In Vitro Techniques | Quinazolines - pharmacology | Index Medicus
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13. Full Text Synthesis and antimycobacterial activity of N′-[( E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives
by Vergara, Fátima M.F and Lima, Camilo H. da S and Henriques, Maria das Graças M. de O and Candéa, André L.P and Lourenço, Maria C.S and Ferreira, Marcelle de L and Kaiser, Carlos R and de Souza, Marcus V.N
European journal of medicinal chemistry, ISSN 0223-5234, 2009, Volume 44, Issue 12, pp. 4954 - 4959
Drugs | N-Acylhydrazones | Pyrazine | Antimycobacterial activity | Biological and medical sciences | Medical sciences | Antibacterial agents | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Antitubercular Agents - chemical synthesis | Hydrazines - pharmacology | Cell Survival | Humans | Antitubercular Agents - pharmacology | Benzylidene Compounds - chemical synthesis | Benzylidene Compounds - chemistry | Mycobacterium tuberculosis - drug effects | Pyrazinamide - chemistry | Anti-Bacterial Agents - chemical synthesis | Microbial Sensitivity Tests | Hydrazines - chemistry | Pyrazinamide - pharmacology | Hydrazines - chemical synthesis | Benzylidene Compounds - pharmacology | Pyrazinamide - chemical synthesis | Drug Design | Macrophages - drug effects | Anti-Bacterial Agents - pharmacology | Molecular Structure | Pyrazinamide | Index Medicus
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14. Full Text Design, synthesis and anticholinesterase activity of novel benzylidenechroman-4-ones bearing cyclic amine side chain
by Pourshojaei, Yaghoub and Gouranourimi, Ali and Hekmat, Shohre and Asadipour, Ali and Rahmani-Nezhad, Samira and Moradi, Alireza and Nadri, Hamid and Moghadam, Farshad Homayouni and Emami, Saeed and Foroumadi, Alireza and Shafiee, Abbas
European journal of medicinal chemistry, ISSN 0223-5234, 06/2015, Volume 97, pp. 181 - 189
Docking study | Acetylcholinesterase | Alzheimer's disease | Chroman-4-one | Homoisoflavonoids | Amines - chemistry | Catalytic Domain | Cholinesterase Inhibitors - chemistry | Models, Molecular | Benzylidene Compounds - chemical synthesis | Cholinesterase Inhibitors - chemical synthesis | Amines - chemical synthesis | Benzylidene Compounds - chemistry | Chromones - chemistry | Benzylidene Compounds - pharmacology | Cholinesterase Inhibitors - pharmacology | Cyclization | Drug Design | Inhibitory Concentration 50 | Chromones - pharmacology | Amines - pharmacology | Chromones - chemical synthesis | Drugstores | Amines | Pharmacy | Index Medicus
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15. Full Text Synthesis, structure, and bioactivity of N′-substituted benzylidene-3,4,5-trimethoxybenzohydrazide and 3-acetyl-2-substituted phenyl-5-(3,4,5-trimethoxyphenyl)-2,3-dihydro-1,3,4-oxadiazole derivatives
by Jin, Linhong and Chen, Jiang and Song, Baoan and Chen, Zhuo and Yang, Song and Li, Qianzhu and Hu, Deyu and Xu, Ruiqing
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2006, Volume 16, Issue 19, pp. 5036 - 5040
Antitumor activity | 1,3,4-Oxadiazole derivatives | Synthesis | 3,4,5-Trimethoxybenzohydrazide | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Cell Survival - drug effects | Oxadiazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Benzylidene Compounds - chemical synthesis | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Benzylidene Compounds - chemistry | Neoplasms - drug therapy | Benzylidene Compounds - pharmacology | Oxadiazoles - pharmacology | Cell Line, Tumor | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Neoplasms - pathology | Oxadiazoles - chemistry | Spectrum Analysis | Drug Screening Assays, Antitumor | Prevention | Cell research | Acetic anhydride | Cancer | Index Medicus
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16. Full Text Synthesis and biological evaluation of 3-substituted 5-benzylidene-1-methyl-2-thiohydantoins as potent NADPH oxidase (NOX) inhibitors
by Bae, Yun Soo and Choi, Sun and Park, Jung Jae and Joo, Jung Hee and Cui, Minghua and Cho, Hyunsung and Lee, Won Jae and Lee, Sang Hyup
Bioorganic & medicinal chemistry, ISSN 0968-0896, 09/2016, Volume 24, Issue 18, pp. 4144 - 4151
NADPH oxidase (NOX) | Thiohydantoin | Benzylidene | Aluminum chloride | Cell Line | Thiohydantoins - pharmacology | Humans | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | NADPH Oxidases - metabolism | Benzylidene Compounds - chemical synthesis | NADPH Oxidase 4 | Enzyme Inhibitors - chemical synthesis | Thiohydantoins - chemical synthesis | Benzylidene Compounds - chemistry | NADPH Oxidase 1 | Animals | Benzylidene Compounds - pharmacology | Enzyme Inhibitors - chemistry | Methylation | Thiohydantoins - chemistry | Oxidases | Analysis | Drugstores | Pharmacy | Index Medicus
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17. Full Text Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors
by Lai, Yisheng and Ma, Lin and Huang, Wenxing and Yu, Xing and Zhang, Yihua and Ji, Hui and Tian, Jide
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2010, Volume 20, Issue 24, pp. 7349 - 7353
Cyclooxygenase | Amino/methylsufonylphenyl | Anti-inflammatory agents | Indolin-2-one derivatives | 5-Lipoxygenase | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Medical sciences | Neuropharmacology | Analgesics | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Analgesics - pharmacology | Indoles - chemical synthesis | Male | Structure-Activity Relationship | Cyclooxygenase 2 Inhibitors - chemistry | Benzylidene Compounds - chemistry | Lipoxygenase Inhibitors - chemical synthesis | Lipoxygenase Inhibitors - chemistry | Analgesics - chemical synthesis | Arachidonate 5-Lipoxygenase - chemistry | Cyclooxygenase 1 - chemistry | Indoles - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Arachidonate 5-Lipoxygenase - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Cyclooxygenase 2 - chemistry | Rats | Benzylidene Compounds - chemical synthesis | Cyclooxygenase Inhibitors - chemistry | Cyclooxygenase Inhibitors - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Benzylidene Compounds - pharmacology | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Anti-Inflammatory Agents - chemical synthesis | Mice | Cyclooxygenase 1 - metabolism | Indoles - chemistry | Lipoxygenase Inhibitors - pharmacology | Index Medicus
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