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Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 09/2015, Volume 25, Issue 17, pp. 3585 - 3591
1,3-Dipolar cycloaddition | Spirooxindole derivatives | Multi-component reactions | Azomethine ylides | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Humans | Indoles - chemical synthesis | Benzylidene Compounds - chemistry | Pyrrolidines - pharmacology | Azo Compounds - chemistry | Thiosemicarbazones - chemistry | Spiro Compounds - chemical synthesis | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Thiosemicarbazones - pharmacology | Azo Compounds - pharmacology | Spiro Compounds - chemistry | Models, Molecular | Thiosemicarbazones - chemical synthesis | Azo Compounds - chemical synthesis | Oxazolone - chemistry | Benzylidene Compounds - chemical synthesis | Antineoplastic Agents - chemistry | Cycloaddition Reaction | Drug Discovery | Pyrrolidines - chemistry | Neoplasms - drug therapy | Oxazolone - analogs & derivatives | Benzylidene Compounds - pharmacology | Oxazolone - chemical synthesis | Pyrrolidines - chemical synthesis | Cell Line, Tumor | Indoles - chemistry | Oxazolone - pharmacology | Spiro Compounds - pharmacology | Index Medicus
Journal Article
Journal of organic chemistry, ISSN 0022-3263, 04/2013, Volume 78, Issue 7, pp. 3445 - 3451
Vinyl Compounds - chemistry | Oxidation-Reduction | Benzoates - chemistry | Isocoumarins - chemical synthesis | Ligands | Organometallic Compounds - chemistry | Benzylidene Compounds - chemical synthesis | Molecular Structure | Catalysis | Benzylidene Compounds - chemistry | Isocoumarins - chemistry | Palladium - chemistry | Thermal properties | Analysis | Oxidation-reduction reaction | Palladium | Chemical properties | Hydrogen bonding | Index Medicus
Journal Article
Journal of organic chemistry, ISSN 0022-3263, 10/2018, Volume 83, Issue 20, pp. 12357 - 12373
Styrenes - chemistry | Oxidation-Reduction | Ketones - chemical synthesis | Stereoisomerism | Epoxy Compounds - chemistry | Spiro Compounds - chemical synthesis | Cycloparaffins - chemical synthesis | Molecular Structure | Catalysis | Benzylidene Compounds - chemistry | Palladium - chemistry | Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 05/2015, Volume 23, Issue 9, pp. 1944 - 1949
Urease inhibition | Oxovanadium(V) complex | Benzohydrazone | Crystal structure | Enzyme Inhibitors - pharmacology | Hydroxamic Acids - chemistry | Models, Molecular | Crystallography, X-Ray | Structure-Activity Relationship | Urease - antagonists & inhibitors | Enzyme Inhibitors - chemical synthesis | Vanadates - chemistry | Benzylidene Compounds - chemistry | Hydrazones - chemistry | Dose-Response Relationship, Drug | Helicobacter pylori - enzymology | Organometallic Compounds - chemical synthesis | Enzyme Inhibitors - chemistry | Vanadates - pharmacology | Organometallic Compounds - chemistry | Urease - metabolism | Molecular Structure | Hydroxamic Acids - pharmacology | Organometallic Compounds - pharmacology | Enzymes | Hydrolases | Structure | Crystals | Index Medicus
Journal Article
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, ISSN 1386-1425, 03/2014, Volume 122, pp. 356 - 364
Antitumor activity | Distannoxane | Antimicrobial activity | Cytotoxic activity | Spectroscopy | Technology | Science & Technology | Butyrates - metabolism | Organotin Compounds - chemistry | Organotin Compounds - metabolism | Anti-Infective Agents - pharmacology | Bacteria - drug effects | Benzylidene Compounds - metabolism | Organotin Compounds - toxicity | Crystallography, X-Ray | Male | Spectroscopy, Fourier Transform Infrared | Benzylidene Compounds - chemistry | Viscosity - drug effects | Butyric Acid - chemistry | Microbial Sensitivity Tests | Organotin Compounds - chemical synthesis | Anti-Infective Agents - chemistry | Fishes | Butyric Acid - toxicity | Antineoplastic Agents - pharmacology | Benzylidene Compounds - toxicity | Cell Death - drug effects | Antifungal Agents - pharmacology | Fungi - drug effects | Magnetic Resonance Spectroscopy | Benzylidene Compounds - chemical synthesis | DNA - metabolism | Butyric Acid - chemical synthesis | Butyrates - chemical synthesis | Artemia - drug effects | Animals | Butyric Acid - metabolism | Butyrates - chemistry | Butyrates - toxicity | Ligands | Plant Tumors | Genetic research | Tin compounds | Structure | Saturated fatty acids | DNA | Crystals
Journal Article
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 07/2017, Volume 80, Issue 7, pp. 2166 - 2169
Stereoisomerism | 4-Butyrolactone - pharmacology | 4-Butyrolactone - chemical synthesis | Benzylidene Compounds - chemical synthesis | Benzylidene Compounds - chemistry | Alkylation | Anti-Bacterial Agents - chemical synthesis | Marine Biology | Myxococcales - chemistry | Benzylidene Compounds - pharmacology | Anti-Bacterial Agents - chemistry | 4-Butyrolactone - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Structure | 4-Butyrolactone - analogs & derivatives | Catalysis | Aldehydes - chemistry | Index Medicus
Journal Article
Journal of fluorescence, ISSN 1053-0509, 1/2016, Volume 26, Issue 1, pp. 189 - 205
Biochemistry, general | Biotechnology | Docking studies | Analytical Chemistry | Biomedicine | DNA interactions | Anti- proliferative activity | Biophysics and Biological Physics | DNA nuclease activity | Anti-bacterial activity | Biomedicine general | Radical scavenging | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Chemistry, Physical | Science & Technology | Free Radical Scavengers - pharmacology | Free Radical Scavengers - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Bacteria - drug effects | Structure-Activity Relationship | Benzylidene Compounds - chemistry | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Naphthyridines - chemical synthesis | MCF-7 Cells | Metals - chemistry | Cattle | Anti-Bacterial Agents - chemistry | Free Radical Scavengers - chemical synthesis | Antineoplastic Agents - pharmacology | Molecular Structure | Cell Survival - drug effects | Naphthyridines - chemistry | Spectrometry, Fluorescence | Benzylidene Compounds - chemical synthesis | Antineoplastic Agents - chemistry | Plasmids - metabolism | Anti-Bacterial Agents - chemical synthesis | DNA - chemistry | Animals | Benzylidene Compounds - pharmacology | Organometallic Compounds - chemical synthesis | Organometallic Compounds - chemistry | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Molecular Docking Simulation | HeLa Cells | Spectrophotometry | DNA Cleavage | Naphthyridines - pharmacology | Organometallic Compounds - pharmacology | Drug Screening Assays, Antitumor | Metals - pharmacology | Antioxidants | Transition metal compounds | DNA | Genetic research | Chemical properties | Cobalt | Antibacterial agents | Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 2008, Volume 16, Issue 7, pp. 3714 - 3724
DEREK | 4-Thiazolidinone derivatives | QSAR | Antibacterial activity/antifungal activity | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | General aspects | Pharmacology. Drug treatments | Antifungal agents | Biological and medical sciences | Medical sciences | Antibacterial agents | Antibiotics. Antiinfectious agents. Antiparasitic agents | Thiazolidines - chemical synthesis | Microbial Viability - drug effects | Benzylidene Compounds - chemical synthesis | Structure-Activity Relationship | Benzylidene Compounds - chemistry | Anti-Bacterial Agents - chemical synthesis | Benzylidene Compounds - pharmacology | Anti-Bacterial Agents - chemistry | Drug Design | Anti-Bacterial Agents - pharmacology | Molecular Structure | Thiazolidines - pharmacology | Thiazolidines - chemistry | Heterocyclic compounds | Pharmacy | Index Medicus
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 2010, Volume 45, Issue 10, pp. 4539 - 4544
Cytotoxicity | Sulforhodamine B assay | 5-benzylidene-2,4-thiazolidinediones | Knoevenagel condensation | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Antineoplastic Agents - chemical synthesis | Humans | Leukemia - drug therapy | Benzylidene Compounds - chemical synthesis | Thiazolidinediones - chemistry | Antineoplastic Agents - chemistry | Benzylidene Compounds - chemistry | Breast Neoplasms - drug therapy | Benzylidene Compounds - pharmacology | Thiazolidinediones - chemical synthesis | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Thiazolidinediones - pharmacology | Drug Screening Assays, Antitumor | Cell research | Analysis | Leukemia | Index Medicus
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 04/2011, Volume 54, Issue 7, pp. 2060 - 2068
Gene Expression Regulation, Enzymologic - drug effects | Arthritis, Experimental - drug therapy | Dinoprostone - biosynthesis | Humans | Nitric Oxide Synthase Type II - chemistry | Thiazolidinediones - toxicity | Male | Dose-Response Relationship, Drug | Inflammation - metabolism | Thiazolidinediones - therapeutic use | Inflammation - drug therapy | Carrageenan - pharmacology | Anti-Inflammatory Agents - therapeutic use | Inhibitory Concentration 50 | Female | Benzylidene Compounds - toxicity | Thiazolidinediones - pharmacology | Cell Line | Nitric Oxide - biosynthesis | Anti-Inflammatory Agents - pharmacology | Anti-Inflammatory Agents - toxicity | Models, Molecular | Rats | Benzylidene Compounds - chemical synthesis | Edema - drug therapy | Animals | Benzylidene Compounds - pharmacology | Thiazolidinediones - chemical synthesis | Benzylidene Compounds - therapeutic use | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Protein Conformation | Anti-Inflammatory Agents - chemical synthesis | Mice | Edema - chemically induced | Inflammation - enzymology | Nitric Oxide Synthase Type II - metabolism | Index Medicus
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 10/2012, Volume 55, Issue 19, pp. 8483 - 8492
Antioxidants - chemistry | Humans | Isoenzymes - chemistry | Structure-Activity Relationship | Amyloid - chemistry | Monoamine Oxidase Inhibitors - chemical synthesis | Zinc - chemistry | Benzylidene Compounds - chemistry | Monoamine Oxidase - chemistry | Copper - chemistry | Indans - chemistry | Iron - chemistry | Chelating Agents - chemistry | Alzheimer Disease - drug therapy | Recombinant Proteins - chemistry | Benzylidene Compounds - chemical synthesis | Antioxidants - chemical synthesis | Peptide Fragments - chemistry | Cations, Divalent | Indans - chemical synthesis | Molecular Docking Simulation | Monoamine Oxidase Inhibitors - chemistry | Amyloid beta-Peptides - chemistry | Chelating Agents - chemical synthesis | Isoenzymes - antagonists & inhibitors | Monoamine Oxidase - metabolism | Index Medicus
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 05/2007, Volume 50, Issue 11, pp. 2665 - 2675
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Antiparasitic agents | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Plasmodium falciparum - enzymology | Quinazolines - chemical synthesis | Rhodanine - chemical synthesis | Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) - antagonists & inhibitors | Furans - pharmacology | Humans | Crystallography, X-Ray | Structure-Activity Relationship | Plasmodium falciparum - drug effects | Quinolines - pharmacology | Rhodanine - analogs & derivatives | Rhodanine - pharmacology | Antimalarials - chemical synthesis | Drug Resistance | Models, Molecular | Benzylidene Compounds - chemical synthesis | Antimalarials - pharmacology | Enoyl-(Acyl-Carrier-Protein) Reductase (NADH) - chemistry | Erythrocytes - drug effects | Triclosan - chemistry | Quinolines - chemical synthesis | Animals | Benzylidene Compounds - pharmacology | Furans - chemical synthesis | Kinetics | Erythrocytes - parasitology | In Vitro Techniques | Quinazolines - pharmacology | Index Medicus
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 2009, Volume 44, Issue 12, pp. 4954 - 4959
Drugs | N-Acylhydrazones | Pyrazine | Antimycobacterial activity | Biological and medical sciences | Medical sciences | Antibacterial agents | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Antitubercular Agents - chemical synthesis | Hydrazines - pharmacology | Cell Survival | Humans | Antitubercular Agents - pharmacology | Benzylidene Compounds - chemical synthesis | Benzylidene Compounds - chemistry | Mycobacterium tuberculosis - drug effects | Pyrazinamide - chemistry | Anti-Bacterial Agents - chemical synthesis | Microbial Sensitivity Tests | Hydrazines - chemistry | Pyrazinamide - pharmacology | Hydrazines - chemical synthesis | Benzylidene Compounds - pharmacology | Pyrazinamide - chemical synthesis | Drug Design | Macrophages - drug effects | Anti-Bacterial Agents - pharmacology | Molecular Structure | Pyrazinamide | Index Medicus
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 06/2015, Volume 97, pp. 181 - 189
Docking study | Acetylcholinesterase | Alzheimer's disease | Chroman-4-one | Homoisoflavonoids | Amines - chemistry | Catalytic Domain | Cholinesterase Inhibitors - chemistry | Models, Molecular | Benzylidene Compounds - chemical synthesis | Cholinesterase Inhibitors - chemical synthesis | Amines - chemical synthesis | Benzylidene Compounds - chemistry | Chromones - chemistry | Benzylidene Compounds - pharmacology | Cholinesterase Inhibitors - pharmacology | Cyclization | Drug Design | Inhibitory Concentration 50 | Chromones - pharmacology | Amines - pharmacology | Chromones - chemical synthesis | Drugstores | Amines | Pharmacy | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2006, Volume 16, Issue 19, pp. 5036 - 5040
Antitumor activity | 1,3,4-Oxadiazole derivatives | Synthesis | 3,4,5-Trimethoxybenzohydrazide | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Cell Survival - drug effects | Oxadiazoles - chemical synthesis | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Benzylidene Compounds - chemical synthesis | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Benzylidene Compounds - chemistry | Neoplasms - drug therapy | Benzylidene Compounds - pharmacology | Oxadiazoles - pharmacology | Cell Line, Tumor | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Molecular Structure | Neoplasms - pathology | Oxadiazoles - chemistry | Spectrum Analysis | Drug Screening Assays, Antitumor | Prevention | Cell research | Acetic anhydride | Cancer | Index Medicus
Journal Article
Bioorganic & medicinal chemistry, ISSN 0968-0896, 09/2016, Volume 24, Issue 18, pp. 4144 - 4151
NADPH oxidase (NOX) | Thiohydantoin | Benzylidene | Aluminum chloride | Cell Line | Thiohydantoins - pharmacology | Humans | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | NADPH Oxidases - metabolism | Benzylidene Compounds - chemical synthesis | NADPH Oxidase 4 | Enzyme Inhibitors - chemical synthesis | Thiohydantoins - chemical synthesis | Benzylidene Compounds - chemistry | NADPH Oxidase 1 | Animals | Benzylidene Compounds - pharmacology | Enzyme Inhibitors - chemistry | Methylation | Thiohydantoins - chemistry | Oxidases | Analysis | Drugstores | Pharmacy | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2010, Volume 20, Issue 24, pp. 7349 - 7353
Cyclooxygenase | Amino/methylsufonylphenyl | Anti-inflammatory agents | Indolin-2-one derivatives | 5-Lipoxygenase | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | Medical sciences | Neuropharmacology | Analgesics | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Analgesics - pharmacology | Indoles - chemical synthesis | Male | Structure-Activity Relationship | Cyclooxygenase 2 Inhibitors - chemistry | Benzylidene Compounds - chemistry | Lipoxygenase Inhibitors - chemical synthesis | Lipoxygenase Inhibitors - chemistry | Analgesics - chemical synthesis | Arachidonate 5-Lipoxygenase - chemistry | Cyclooxygenase 1 - chemistry | Indoles - pharmacology | Cyclooxygenase 2 Inhibitors - chemical synthesis | Arachidonate 5-Lipoxygenase - metabolism | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Cyclooxygenase 2 - chemistry | Rats | Benzylidene Compounds - chemical synthesis | Cyclooxygenase Inhibitors - chemistry | Cyclooxygenase Inhibitors - pharmacology | Animals | Anti-Inflammatory Agents - chemistry | Benzylidene Compounds - pharmacology | Analgesics - chemistry | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Anti-Inflammatory Agents - chemical synthesis | Mice | Cyclooxygenase 1 - metabolism | Indoles - chemistry | Lipoxygenase Inhibitors - pharmacology | Index Medicus
Journal Article