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Toxicology and Applied Pharmacology, ISSN 0041-008X, 01/2014, Volume 274, Issue 2, pp. 328 - 338
Induction of fibrosis during prolonged culture of precision-cut liver slices (PCLS) was reported. In this study, the use of rat PCLS was investigated to... 
Early onset of fibrosis | Precision-cut liver slices | Antifibrotic drugs | Liver fibrosis | Ex vivo model | ROSMARINIC ACID | ANGIOTENSIN-II | ANTI-FIBROTIC DRUGS | IN-VITRO | INHIBITS ACTIVATION | HEPATIC STELLATE CELLS | PHARMACOLOGY & PHARMACY | ENDOPLASMIC-RETICULUM | DERMAL FIBROBLASTS | TOXICOLOGY | GROWTH-FACTOR | IMATINIB MESYLATE | Niacinamide - analogs & derivatives | Rats, Wistar | Transforming Growth Factor beta1 - antagonists & inhibitors | Transforming Growth Factor beta1 - metabolism | Male | Valproic Acid - pharmacology | Depsides - pharmacology | Perindopril - pharmacology | Collagen Type I - genetics | Liver - drug effects | Benzamides - pharmacology | Benzylisoquinolines - pharmacology | Organ Culture Techniques | Liver Cirrhosis - drug therapy | Gene Expression | Collagen Type I - metabolism | Proto-Oncogene Proteins c-sis - genetics | Proto-Oncogene Proteins c-sis - metabolism | Down-Regulation | Liver - metabolism | Rats | Transforming Growth Factor beta1 - genetics | Pyrimidines - pharmacology | Cinnamates - pharmacology | HSP47 Heat-Shock Proteins - genetics | Imatinib Mesylate | Piperazines - pharmacology | Animals | Models, Biological | HSP47 Heat-Shock Proteins - metabolism | Connective Tissue Growth Factor - genetics | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Connective Tissue Growth Factor - metabolism | Pyridones - pharmacology | Proto-Oncogene Proteins c-sis - antagonists & inhibitors | Drugs | Liver diseases | Analysis | Liver | Fibrosis | Gene expression | Growth factors | Index Medicus | FIBROSIS | DRUGS | GENES | LIVER | RATS | 60 APPLIED LIFE SCIENCES | ATP
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 3, pp. 551 - 561
Vomeronasal sensory neurons play a crucial role in detecting pheromones, but the chemoelectrical transduction mechanism remains unclear and controversial. A... 
CALCIUM TRANSIENTS | MOUSE TRANSIENT RECEPTOR | CA2+ ENTRY | CYCLIC-GMP | FATTY-ACIDS | STORE DEPLETION | ION CHANNELS | SENSITIVE CHANNELS | NEUROSCIENCES | RECEPTOR POTENTIAL CHANNEL | SENSORY NEURONS | Electric Stimulation | Ion Channels | Calcium - metabolism | Inositol 1,4,5-Trisphosphate - pharmacology | Electric Conductivity | Sodium - metabolism | Diacylglycerol Kinase - antagonists & inhibitors | Dose-Response Relationship, Drug | Calcium Channels - physiology | Drug Interactions | Diglycerides - pharmacology | Mice, Mutant Strains | Dendrites - physiology | Neurons - physiology | TRPM Cation Channels | Vomeronasal Organ - physiology | Urine - physiology | Neurons - drug effects | Calcium Channels - genetics | Benzylisoquinolines - pharmacology | Membrane Potentials - drug effects | Boron Compounds - pharmacology | Dendrites - drug effects | Alkaloids - pharmacology | Diglycerides - analysis | Signal Transduction | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Vomeronasal Organ - cytology | Pheromones - metabolism | Calcium Channel Blockers - pharmacology | Evoked Potentials - drug effects | Membrane Proteins | Patch-Clamp Techniques | Animals | Diglycerides - chemistry | Arachidonic Acid - pharmacology | Glutamates - pharmacology | Mice | In Vitro Techniques | Studies | Signal transduction | Rodents | Pheromones | Behavior | Glucose | Mammals | Experiments | Index Medicus
Journal Article
Journal Article
Phytomedicine, ISSN 0944-7113, 07/2014, Volume 21, Issue 8-9, pp. 1110 - 1119
Journal Article
Planta Medica, ISSN 0032-0943, 05/2011, Volume 77, Issue 8, pp. 835 - 840
Journal Article
by Wan, J and Liu, T and Mei, L and Li, J and Gong, K and Yu, C and Li, W
British Journal of Cancer, ISSN 0007-0920, 07/2013, Volume 109, Issue 2, pp. 342 - 350
Journal Article
Cancer Letters, ISSN 0304-3835, 11/2017, Volume 409, pp. 91 - 103
Cholesterol is an important modulator of membrane protein function and signaling in endothelial cells, thus making it an emerging target for anti-angiogenic... 
Cholesterol trafficking | Angiogenesis | Tumor | Cepharanthine | Lysosome | MIGRATION | PROTEIN | DRUG DISCOVERY | ITRACONAZOLE | MTOR | LUNG-CANCER | PHASE-II TRIAL | IN-VITRO | THERAPY | ONCOLOGY | INHIBITS ANGIOGENESIS | Neoplasms - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | Neovascularization, Pathologic - pathology | Lysosomes - metabolism | Benzylisoquinolines - administration & dosage | Benzylisoquinolines - pharmacology | Lysosomes - drug effects | Tumor Microenvironment - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Animals, Genetically Modified | Cell Growth Processes - drug effects | Angiogenesis Inhibitors - pharmacology | Neoplasms - blood supply | Zebrafish | Cisplatin - pharmacology | Cholesterol - metabolism | Mice, SCID | Neoplasms - drug therapy | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Neovascularization, Pathologic - drug therapy | Mice, Inbred NOD | Mice | Neovascularization, Pathologic - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | Neoplasms - pathology | Antimitotic agents | Chemotherapy | Growth | Low density lipoproteins | Medical screening | Antineoplastic agents | Drug approval | Cholesterol | Endothelium | Cancer | Tumors | Protein binding | TOR protein | Niemann-Pick disease | Drugs | Lung | Lung cancer | Trafficking | Lysosomes | Metastasis | Kinases | pH effects | Cancer therapies | Cell adhesion & migration | Anticancer properties | Proteins | Antitumor agents | Xenografts | Npc1 protein | Inhibition | Vascular endothelial growth factor | Immunoglobulins | Breast cancer | Pharmacology | Inflammation | Cells | Cisplatin | Endothelial cells | Membrane proteins | Inhibitors | Antitumor activity | Angiogenesis inhibitors | Prostate cancer | Index Medicus | cepharanthine | lysosome | angiogenesis | tumor
Journal Article