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The Journal of Clinical Pharmacology, ISSN 0091-2700, 02/2017, Volume 57, Issue 2, pp. 151 - 160
Journal Article
BioFactors, ISSN 0951-6433, 09/2016, Volume 42, Issue 5, pp. 545 - 555
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 12/2013, Volume 8, Issue 1, pp. 4677 - 4687
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2015, Volume 5, Issue 1, p. 12961
.... In this work, we characterized the chemical constituents in K-601, identified the absorbed compounds and determined their pharmacokinetics in 6 Chinese and African volunteers by liquid chromatography... 
EXTRACTION | LIQUID-CHROMATOGRAPHY | PANAX-GINSENG | DRUG-INTERACTIONS | MULTIDISCIPLINARY SCIENCES | MEDICINES | GINSENOSIDES | IDENTIFICATION | MASS-SPECTROMETRY | GINSENG SAPONINS | CONSTITUENTS | Berberine - administration & dosage | Alkaloids - pharmacokinetics | Humans | Middle Aged | Male | Chromatography, High Pressure Liquid | Healthy Volunteers | Spectrometry, Mass, Electrospray Ionization | Berberine - analogs & derivatives | Benzylisoquinolines - administration & dosage | Aporphines - pharmacokinetics | Aporphines - blood | Adult | Benzylisoquinolines - pharmacokinetics | Berberine - pharmacokinetics | Berberine Alkaloids - administration & dosage | Drugs, Chinese Herbal - administration & dosage | Berberine Alkaloids - blood | Berberine - blood | Aporphines - administration & dosage | Benzylisoquinolines - blood | Drugs, Chinese Herbal - pharmacokinetics | Asian Continental Ancestry Group | Berberine Alkaloids - pharmacokinetics | Alkaloids - blood | Alkaloids - administration & dosage | African Continental Ancestry Group | Berberine | Hydroxylation | Microflora | Ions | Mass spectroscopy | Liquid chromatography | Herbal medicine | Alkaloids | Demethylation | Metabolites | Intestine | Influenza | Biotransformation | Metabolic pathways | Intestinal microflora | Acetylation | Pharmacokinetics | Methylation
Journal Article
Pharmaceutical Biology, ISSN 1388-0209, 01/2017, Volume 55, Issue 1, pp. 510 - 515
...)] that is widely used for the treatment of diabetes, hyperlipidemia and hypertension. However, the pharmacokinetics of berberine in normal rats and type 2 diabetes mellitus (T2DM... 
Berberine | LC-MS/MS | T2DM | Pharmacokinetics | HEPATIC GLUCONEOGENESIS | OXIDATIVE STRESS | MECHANISM | RHIZOMA-COPTIDIS EXTRACT | CANCER | PLANT SCIENCES | PATHWAY | UPLC-MS/MS METHOD | INSULIN-RESISTANCE | PHARMACOLOGY & PHARMACY | MICE | MEDICAL LABORATORY TECHNOLOGY | ALKALOIDS | Berberine - administration & dosage | Diabetes Mellitus, Experimental - drug therapy | Area Under Curve | Streptozocin | Antihypertensive Agents - administration & dosage | Half-Life | Male | Metabolic Clearance Rate | Diabetes Mellitus, Experimental - blood | Hypoglycemic Agents - blood | Tandem Mass Spectrometry | Hypolipidemic Agents - blood | Hypoglycemic Agents - administration & dosage | Diet, High-Fat | Chromatography, Liquid | Berberine - pharmacokinetics | Diabetes Mellitus, Experimental - chemically induced | Hypoglycemic Agents - pharmacokinetics | Reproducibility of Results | Administration, Oral | Berberine - blood | Antihypertensive Agents - pharmacokinetics | Biomarkers - blood | Rats, Sprague-Dawley | Antihypertensive Agents - blood | Blood Glucose - drug effects | Animals | Hypolipidemic Agents - administration & dosage | Blood Glucose - metabolism | Hypolipidemic Agents - pharmacokinetics | Hyperlipidemia | Peripheral blood | Glucose | Diabetes | Diabetes mellitus (non-insulin dependent) | High fat diet
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 03/2018, Volume 9, p. 214
.... In this study, for the first time we describe gut microbiota-regulated pharmacokinetics in beagle dogs after oral administration of BBR by single (50 mg/kg) or multiple doses (50 mg/kg/d) for 7 days... 
GC-MS | Gut microbiota | LC/MS | Berberine | Metabolites | 16S rRNA genes analysis | IT-TOF | Butyrate | butyrate | RATS | EXCRETION | metabolites | gut microbiota | LC/MSn-IT-TOF | berberine | IN-VITRO | PLASMA | CHAIN FATTY-ACIDS | PHARMACOLOGY & PHARMACY | Cell metabolism | Microbiota (Symbiotic organisms) | Observations | Health aspects
Journal Article
Tropical Journal of Pharmaceutical Research, ISSN 1596-5996, 08/2017, Volume 16, Issue 8, pp. 2039 - 2046
Purpose: To study the pharmacokinetics and tissue distribution of N-3-methoxybenzyl-palmitamide (MPM... 
Lepidium meyenii | UPLC-MS/MS | Maca tuber | Tissue distribution | Pharmacokinetics | Macamide | PLASMA | BERBERINE | PHARMACOLOGY & PHARMACY | MICE | TANDEM MASS-SPECTROMETRY | MS/MS
Journal Article