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PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, pp. e107129 - e107129
The global incidence of metabolic and age-related diseases, including type 2 diabetes and Alzheimer's disease, is on the rise. In addition to traditional... 
EXCITOTOXICITY | APOPTOSIS-INDUCING FACTOR | IN-VITRO | COPTIDIS | MULTIDISCIPLINARY SCIENCES | DYSFUNCTION | EXPRESSION | RAT MODEL | K+ CHANNELS | CELL-DEATH | IMPAIRMENT | Neurons - pathology | Receptors, N-Methyl-D-Aspartate - drug effects | Glutamic Acid - pharmacology | Rats, Wistar | Embryo, Mammalian | Humans | Cells, Cultured | Receptors, N-Methyl-D-Aspartate - metabolism | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, N-Methyl-D-Aspartate - genetics | Neurotoxins - pharmacology | Animals | Drug Interactions | HEK293 Cells | Rotenone - pharmacology | Mice | Neurons - metabolism | Berberine - toxicity | Neurons - drug effects | Type 2 diabetes | Brain | Methyl aspartate | Nervous system diseases | Neurons | Alternative medicine | Mitochondrial DNA | Glutamate | Alzheimer's disease | Injuries | Oxidative stress | Neurosciences | Parkinson's disease | Toxicity | Glutamic acid receptors (ionotropic) | Central nervous system | Parkinsons disease | Drug development | Kinases | Caspase-3 | MK-801 | Neurotoxicity | Receptors | Mitochondria | Head injuries | Ischemia | Neurodegeneration | Rodents | Membrane potential | Safety | Drug dosages | Age | Movement disorders | Berberine | Neurodegenerative diseases | Diabetes mellitus | Caspase | N-Methyl-D-aspartic acid receptors | Pharmacology | Bioavailability | Rotenone | Neurological diseases | Bradycardia | Memantine | Antibiotics | Excitotoxicity | Diabetes | Laboratory animals | Alzheimers disease | Brain injury | Acute toxicity | Apoptosis | Index Medicus
Journal Article
Toxicology Letters, ISSN 0378-4274, 05/2013, Volume 219, Issue 2, pp. 178 - 193
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 01/2018, Volume 97, pp. 233 - 239
Hepatotoxicity is one of the major side effects of methotrexate (MTX), which restricts the clinical use of this drug. Berberine (BBR) is a natural compound... 
Antioxidants | Berberine | Rat | Methotrexate | Hepatotoxicity | GENTAMICIN-INDUCED NEPHROTOXICITY | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | OXIDATIVE STRESS | ACID | DAMAGE | INFLAMMATION | ASSAYS | PHARMACOLOGY & PHARMACY | KIDNEY | INDUCED HEPATOTOXICITY | EXTRACT | Superoxide | Phosphatases | Nitric oxide | Liver
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 05/2016, Volume 13, Issue 5, pp. 3953 - 3960
Doxorubicin (DOX), a potent broad-spectrum chemotherapeutic agent used for the treatment of several types of cancer, is largely limited due to its serious side... 
Berberine | Oxidative damage | Doxorubicin | Hepatorenal toxicity | CANCER-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | ACTIVATED PROTEIN-KINASE | oxidative damage | hepatorenal toxicity | DAMAGE | berberine | INDUCED CARDIOTOXICITY | ONCOLOGY | PATHWAY | INDUCED OXIDATIVE STRESS | MICE | doxorubicin | HEPATOTOXICITY | CONGESTIVE-HEART-FAILURE | Index Medicus
Journal Article