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Biomaterials, ISSN 0142-9612, 2016, Volume 86, pp. 42 - 55
Journal Article
Nature, ISSN 0028-0836, 04/2011, Volume 472, Issue 7341, pp. 57 - 65
Metabolomics studies hold promise for the discovery of pathways linked to disease processes. Cardiovascular disease (CVD) represents the leading cause of death... 
CHLAMYDIA-PNEUMONIAE | TRIMETHYLAMINE-N-OXIDE | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | MURINE MACROPHAGES | MOUSE | GENE-EXPRESSION | ATHEROSCLEROSIS | MICE | CORONARY-HEART-DISEASE | MASS-SPECTROMETRY | Choline - metabolism | Dietary Fats - metabolism | Metabolomics | Liver - enzymology | Diet - adverse effects | Atherosclerosis - genetics | Betaine - metabolism | Humans | Phosphatidylcholines - administration & dosage | Phosphatidylcholines - metabolism | Choline - blood | Dietary Fats - pharmacology | Oxygenases - metabolism | Cardiovascular Diseases - blood | Female | Atherosclerosis - microbiology | Betaine - blood | Methylamines - pharmacology | Cardiovascular Diseases - diagnosis | Methylamines - metabolism | Receptors, Scavenger - metabolism | Biomarkers - metabolism | Phosphatidylcholines - blood | Cardiovascular Diseases - metabolism | Risk Assessment | Atherosclerosis - chemically induced | Mice, Inbred C57BL | Phosphatidylcholines - pharmacology | Gene Expression Regulation | Methylamines - blood | Gastrointestinal Tract - microbiology | Biomarkers - blood | Dietary Fats - blood | Atherosclerosis - metabolism | Gastrointestinal Tract - metabolism | Cardiovascular Diseases - microbiology | Macrophages - metabolism | Phenotype | Animals | Choline - administration & dosage | Choline - pharmacology | Germ-Free Life | Cholesterol, HDL - blood | Mice | Oxygenases - genetics | Lecithin | Microbiota (Symbiotic organisms) | Physiological aspects | Research | Cardiovascular diseases | Metabolism | Health aspects | Risk factors | Plasma | Nuclear magnetic resonance--NMR | Heart attacks | Pathogenesis | Lipids | Cardiovascular disease | Probiotics | Metabolites | Diet | Atherosclerosis | Bacteria | Insulin resistance | Mass spectrometry | atherosclerosis | intestinal microbiota | choline | diet | phospholipid | metabolomics
Journal Article
Journal Article
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 06/2016, Volume 143, pp. 246 - 253
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 2000, Volume 279, Issue 3, pp. F584 - F591
L-Carnitine is essential for the translocation of acyl-carnitine into the mitochondria for beta-oxidation of long-chain fatty acids. It is taken up into the... 
Carnitine transport | Pharmacology | Human sodium-driven organic cation transporter 2 | Secondary carnitine deficiency | Tetraethylammonium - pharmacology | Protein Synthesis Inhibitors - chemistry | Emetine - pharmacology | Humans | Amino Acids - chemistry | Tritium | Sodium - metabolism | Valproic Acid - pharmacology | Amino Acids - pharmacology | Solute Carrier Family 22 Member 5 | Carnitine - deficiency | Enzyme Inhibitors - chemistry | Pentanoic Acids - chemistry | Pentanoic Acids - pharmacology | Carrier Proteins - chemistry | Biological Transport - drug effects | Membrane Proteins - metabolism | Protein Synthesis Inhibitors - pharmacology | Valproic Acid - chemistry | Membrane Potentials - drug effects | Tetraethylammonium - chemistry | RNA, Complementary - pharmacology | Lipotropic Agents - chemistry | Emetine - chemistry | Microinjections | Membrane Proteins - genetics | Xenopus laevis | Enzyme Inhibitors - pharmacology | Organic Cation Transport Proteins | Carnitine - chemistry | Betaine - pharmacology | Membrane Potentials - physiology | Betaine - chemistry | Carrier Proteins - genetics | Patch-Clamp Techniques | Animals | Carrier Proteins - metabolism | Oocytes - physiology | Membrane Proteins - chemistry | Lipotropic Agents - pharmacology | Biological Transport - physiology | Carnitine - pharmacokinetics | Hydrogen-Ion Concentration
Journal Article
Advanced Healthcare Materials, ISSN 2192-2640, 06/2017, Volume 6, Issue 11, pp. 1601428 - n/a
Polymer–protein conjugation has been extensively explored toward a better protein drug with improved pharmacokinetics. However, a major problem with... 
protein–polymer conjugation | insulin modification | zwitterion | bioactivity | NANOPARTICLES | MATERIALS SCIENCE, BIOMATERIALS | CIRCULAR-DICHROISM | ACID | PHARMACOKINETICS | ENGINEERING, BIOMEDICAL | STABILITY | NANOSCIENCE & NANOTECHNOLOGY | ACCUMULATION | LIPOSOMES | PEGYLATION | DELIVERY | Insulin - pharmacology | Diabetes Mellitus, Experimental - drug therapy | Immobilized Proteins - chemistry | Delayed-Action Preparations - chemistry | Betaine - pharmacology | Betaine - pharmacokinetics | Diabetes Mellitus, Experimental - blood | Betaine - chemistry | Immobilized Proteins - pharmacokinetics | Animals | Insulin - chemistry | Delayed-Action Preparations - pharmacology | Immobilized Proteins - pharmacology | Delayed-Action Preparations - pharmacokinetics | Polymers - pharmacokinetics | Polymers - pharmacology | Polymers - chemistry | Mice | Insulin - pharmacokinetics | Surface active agents | Polymers | Blood sugar | Insulin | Surgical implants | Conjugates | Separation | Biochemistry | Glucose | Blood | LITAF protein | Proteins | PCB compounds | Biomedical materials | Biocompatibility | Manufacturing | Coupling | Chemical synthesis | Pharmacology | Chemical compounds | Chromatography | Biological activity | PCB | Chemistry | Isoforms | Polychlorinated biphenyls | Conjugation | Pharmacokinetics | In vitro methods and tests
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 09/2000, Volume 279, Issue 3, pp. 584 - 591
l-Carnitine is essential for the translocation of acyl-carnitine into the mitochondria for β-oxidation of long-chain fatty acids. It is taken up into the cells... 
secondary carnitine deficiency | CELLS | PHYSIOLOGY | CATION/CARNITINE TRANSPORTER | ACID | SPECIFICITY | RAT-KIDNEY | DEFICIENCY | human sodium-driven organic cation transporter 2 | ORGANIC CATION TRANSPORTERS | BORDER-MEMBRANE-VESICLES | pharmacology | UROLOGY & NEPHROLOGY | MOLECULAR-CLONING | carnitine transport | OCTN2
Journal Article