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bibenzyls - pharmacology (218) 218
index medicus (216) 216
chemistry, medicinal (208) 208
humans (190) 190
bibenzyls - chemistry (167) 167
pharmacology & pharmacy (160) 160
animals (150) 150
molecular structure (105) 105
structure-activity relationship (89) 89
cell line, tumor (86) 86
antineoplastic agents (82) 82
antineoplastic agents - pharmacology (81) 81
plant sciences (78) 78
biochemistry & molecular biology (71) 71
mice (70) 70
bibenzyls - chemical synthesis (65) 65
bibenzyls - isolation & purification (63) 63
drug screening assays, antitumor (61) 61
cell proliferation - drug effects (58) 58
antineoplastic agents - chemistry (57) 57
antineoplastic agents, phytogenic - pharmacology (57) 57
stilbenes - pharmacology (57) 57
chemistry, organic (56) 56
derivatives (53) 53
cancer (52) 52
analysis (51) 51
bibenzyls (51) 51
antineoplastic agents - chemical synthesis (47) 47
tubulin (46) 46
bibenzyl (44) 44
chemistry, applied (44) 44
stilbenes - chemistry (44) 44
cytotoxicity (42) 42
magnetic resonance spectroscopy (42) 42
stilbenes (42) 42
apoptosis (41) 41
antimitotic agents (40) 40
tubulin - metabolism (40) 40
dendrobium - chemistry (39) 39
rats (39) 39
tubulin modulators - pharmacology (38) 38
chemistry, multidisciplinary (36) 36
dose-response relationship, drug (36) 36
female (36) 36
inhibitory concentration 50 (36) 36
male (35) 35
apoptosis - drug effects (34) 34
cell survival - drug effects (34) 34
oncology (34) 34
bibenzyl derivatives (33) 33
constituents (33) 33
tubulins (32) 32
analogs (31) 31
tubulin modulators - chemistry (31) 31
combretastatin a-4 (30) 30
models, molecular (30) 30
biological evaluation (29) 29
antitumor-activity (28) 28
bryophytes (28) 28
in-vitro (28) 28
polymerization (28) 28
inhibition (27) 27
neoplasms - drug therapy (27) 27
tumor cells, cultured (27) 27
antineoplastic agents, phytogenic - chemistry (26) 26
colchicine (26) 26
combretastatin (26) 26
drug design (26) 26
hepatophyta - chemistry (25) 25
liverwort (25) 25
orchidaceae (25) 25
orchidaceae - chemistry (25) 25
bibenzyls - therapeutic use (24) 24
stilbenes - chemical synthesis (24) 24
tubulin - chemistry (24) 24
a-4 (22) 22
cell line (22) 22
chemical-constituents (22) 22
microbial sensitivity tests (22) 22
molecular conformation (22) 22
plants, medicinal - chemistry (22) 22
tubulin modulators - chemical synthesis (22) 22
tubulin polymerization (22) 22
a4 phosphate (21) 21
liverworts (21) 21
potent (21) 21
chemosystematics (20) 20
phenanthrenes (20) 20
stereoisomerism (20) 20
anti-bacterial agents - pharmacology (19) 19
cells (19) 19
ethers, cyclic - pharmacology (19) 19
inhibitors (19) 19
phenanthrenes - chemistry (19) 19
phenyl ethers - pharmacology (19) 19
plant extracts - chemistry (19) 19
antifungal agents - pharmacology (18) 18
plant extracts - pharmacology (18) 18
stilbenoids (18) 18
angiogenesis (17) 17
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Journal of Natural Products, ISSN 0163-3864, 09/2013, Volume 76, Issue 9, pp. 1668 - 1678
Journal Article
Journal of Natural Products, ISSN 0163-3864, 05/2007, Volume 70, Issue 5, pp. 795 - 801
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2010, Volume 53, Issue 10, pp. 4248 - 4258
A series of 1-aryl-5-(3',4',5'-trimethoxyphenyl) derivatives and their related 1-(3',4',5'-trimethoxyphenyl)5-aryl-1,2,4-triazoles, designed as cis-restricted... 
MEDICINAL CHEMISTRY | CYTOCHROME-C | IN-VITRO | CHEMISTRY, MEDICINAL | COLCHICINE SITE | CANCER CELLS | A-4 ANALOGS | TUBULIN POLYMERIZATION | MICROTUBULE DYNAMICS | A4 PHOSPHATE | CELL-DEATH | Reactive Oxygen Species - metabolism | Triazoles - chemistry | Tubulin Modulators - pharmacology | Antineoplastic Agents - chemical synthesis | Humans | Caspase 3 - metabolism | Structure-Activity Relationship | Membrane Potential, Mitochondrial - drug effects | Bibenzyls - chemistry | G2 Phase - drug effects | Tubulin Modulators - chemical synthesis | Cell Shape | Triazoles - chemical synthesis | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Angiogenesis Inhibitors - chemical synthesis | Colchicine - chemistry | Endothelial Cells - physiology | Tubulin Modulators - chemistry | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Models, Molecular | Mitochondria - drug effects | Antineoplastic Agents - chemistry | Chick Embryo | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Bibenzyls - chemical synthesis | Triazoles - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Endothelial Cells - cytology | Cell Line, Tumor | Protein Binding | Bibenzyls - pharmacology | Enzyme Activation | Mitochondria - physiology | Angiogenesis Inhibitors - chemistry | Apoptosis | Drug Screening Assays, Antitumor | Endothelial Cells - drug effects
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2019, Volume 170, pp. 87 - 98
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2006, Volume 49, Issue 11, pp. 3143 - 3152
We studied the anticancer activity of a series of new combretastatin derivatives with B-ring modifications. The structure-activity relationship (SAR)... 
CHEMISTRY, MEDICINAL | VASCULAR TARGETING AGENTS | PRODRUGS | ANTINEOPLASTIC AGENTS | TUBULIN POLYMERIZATION | BIOLOGICAL EVALUATION | ANTIMITOTIC AGENT | A-4 | CELL-LINES | A4 PHOSPHATE | CANCER-THERAPY | Endothelium, Vascular - cytology | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Bibenzyls - pharmacokinetics | Humans | Stilbenes - chemical synthesis | Benzofurans - pharmacology | Structure-Activity Relationship | Stilbenes - pharmacology | Biopolymers | Benzofurans - pharmacokinetics | Endothelial Cells - ultrastructure | Tubulin - metabolism | Microtubules - drug effects | Microtubules - ultrastructure | Organophosphates - chemical synthesis | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Colchicine - chemistry | Binding, Competitive | Organophosphates - pharmacokinetics | Benzofurans - chemical synthesis | Thiophenes - pharmacology | Cell Nucleus - ultrastructure | Bibenzyls - chemical synthesis | Organophosphates - pharmacology | Xenograft Model Antitumor Assays | Thiophenes - chemical synthesis | Thiophenes - pharmacokinetics | Animals | Prodrugs - pharmacokinetics | Mice, Nude | Cell Line, Tumor | Prodrugs - chemical synthesis | Stilbenes - pharmacokinetics | Bibenzyls - pharmacology | Mice | Cell Nucleus - drug effects | Prodrugs - pharmacology | Endothelial Cells - drug effects
Journal Article
Toxicology Letters, ISSN 0378-4274, 04/2017, Volume 271, pp. 74 - 83
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2009, Volume 17, Issue 22, pp. 7711 - 7722
Journal Article
Journal Article