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Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
Journal Article
Nature Neuroscience, ISSN 1097-6256, 03/2005, Volume 8, Issue 3, pp. 354 - 364
Microcircuits composed of principal neuron and interneuron dendrites have an important role in shaping the representation of sensory information in the... 
CALCIUM-CHANNELS | NMDA RECEPTORS | MEMBRANE-POTENTIALS | GABA RELEASE | MITRAL CELLS | DENDRODENDRITIC INHIBITION | GRANULE CELLS | PERIGLOMERULAR CELLS | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | SYNAPTIC ORGANIZATION | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Membrane Potentials - radiation effects | Drug Interactions | Time Factors | Synaptic Transmission - drug effects | Neural Conduction - drug effects | Tetrodotoxin - pharmacology | Nickel - pharmacology | Olfactory Bulb - cytology | Animals, Newborn | Membrane Potentials - drug effects | Dendrites - drug effects | Calcium - pharmacology | Cadmium - pharmacology | Rats | Neural Conduction - physiology | Bicuculline - pharmacology | Chelating Agents - pharmacology | Pyrimidines - pharmacology | Potassium - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Signal Transduction - drug effects | Calcium Signaling - drug effects | Phosphinic Acids - pharmacology | Dihydropyridines - pharmacology | Neurons - radiation effects | Neural Conduction - radiation effects | Synaptic Transmission - physiology | Calcium Signaling - physiology | Neurons - cytology | Nimodipine - pharmacology | Patch-Clamp Techniques - methods | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Neural Inhibition - physiology | Neurons - physiology | Neurons - drug effects | Electric Stimulation - methods | Neural Networks (Computer) | Dendrites - metabolism | Synapses - physiology | Calcium Signaling - radiation effects | Valine - analogs & derivatives | 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester - pharmacology | Calcium Channel Blockers - pharmacology | Membrane Potentials - physiology | Dendrites - radiation effects | Animals | Egtazic Acid - pharmacology | Synaptic Transmission - radiation effects | Calcium Channel Agonists - pharmacology | Signal Transduction - physiology | Valine - pharmacology | In Vitro Techniques | Propanolamines - pharmacology | Neural Inhibition - drug effects | Physiological aspects | Olfactory bulb | Cellular signal transduction | Neural circuitry | Research | Index Medicus
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 12, pp. 3992 - 4003
The NMDAR plays a unique and vital role in subcellular signaling. Calcium influx initiates signaling cascades important for both synaptic plasticity and... 
IN-VITRO | STATE TRANSITIONS | LONG-TERM POTENTIATION | SUBUNIT COMPOSITION | D-ASPARTATE RECEPTOR | HUNTINGTONS-DISEASE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | DIFFERENTIAL ROLES | CELL-DEATH | NUCLEUS-ACCUMBENS | Microfluidic Analytical Techniques - methods | Electric Stimulation | Rats, Wistar | Embryo, Mammalian | Coculture Techniques | Receptors, N-Methyl-D-Aspartate - metabolism | Neurons - cytology | Cerebral Cortex - cytology | Corpus Striatum - cytology | N-Methylaspartate - pharmacology | CREB-Binding Protein - metabolism | Glycine Agents - pharmacology | Transfection - methods | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Tetrodotoxin - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | GABA-A Receptor Antagonists - pharmacology | Nifedipine - pharmacology | Synapses - physiology | Vesicular Glutamate Transport Protein 1 - metabolism | Cells, Cultured | Rats | Sodium Channel Blockers - pharmacology | Strychnine - pharmacology | Bicuculline - pharmacology | Calcium Channel Blockers - pharmacology | Nerve Tissue Proteins - metabolism | Pregnancy | Patch-Clamp Techniques | Animals | Analysis of Variance | Glutamate Decarboxylase - metabolism | Luminescent Proteins - genetics | Signal Transduction - physiology | Luminescent Proteins - metabolism | Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2009, Volume 62, Issue 1, pp. 53 - 71
The molecular mechanisms controlling the termination of cortical interneuron migration are unknown. Here, we demonstrate that, prior to synaptogenesis,... 
CELLBIO | DEVBIO | MOLNEURO | NEURONAL MIGRATION | CHLORIDE HOMEOSTASIS | DOWN-REGULATION | GABAERGIC INTERNEURONS | GENE-EXPRESSION | CL-COTRANSPORTER KCC2 | TANGENTIAL MIGRATION | DEVELOPING CEREBRAL-CORTEX | NEUROSCIENCES | MEDIAL GANGLIONIC EMINENCE | INTERMEDIATE ZONE | Interneurons - physiology | Muscimol - pharmacology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Sequence Deletion | Age Factors | Calcium - metabolism | Embryo, Mammalian | Microtubule-Associated Proteins - metabolism | Green Fluorescent Proteins - genetics | Cerebral Cortex - cytology | Cell Movement - physiology | Quinoxalines - pharmacology | omega-Conotoxin GVIA - pharmacology | Symporters - antagonists & inhibitors | Female | Organ Culture Techniques | Bicuculline - analogs & derivatives | Animals, Newborn | Membrane Potentials - drug effects | Nifedipine - pharmacology | Glutamic Acid - pharmacology | RNA, Small Interfering - pharmacology | Valine - analogs & derivatives | gamma-Aminobutyric Acid - pharmacology | Calcium Channels, L-Type - physiology | Mice, Transgenic | Bicuculline - pharmacology | Calcium Channel Blockers - pharmacology | Electroporation - methods | Membrane Potentials - physiology | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Symporters - metabolism | Gene Expression Regulation - drug effects | Pregnancy | Cell Movement - drug effects | GABA Agents - pharmacology | Animals | Models, Biological | Symporters - genetics | LIM-Homeodomain Proteins | Mice | Mice, Inbred BALB C | Transcription Factors | Valine - pharmacology | GABA | Methyl aspartate | Calcium channels | Neurosciences | Glutamate | Membrane potentials | Brain | Motility | Microscopy | Neurons | Rodents | Migration | Colleges & universities | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2010, Volume 30, Issue 20, pp. 6999 - 7016
Whole-cell recordings were obtained from tyrosine hydroxylase-expressing (TH+) neurons in striatal slices from bacterial artificial chromosome transgenic mice... 
AMINO-ACID DECARBOXYLASE | IMMUNOREACTIVE NEURONS | RAT NEOSTRIATAL NEURONS | SLICE PREPARATION | BASAL GANGLIA | ELECTRICAL MEMBRANE-PROPERTIES | GABAERGIC INTERNEURONS | SPINY PROJECTION NEURONS | DOPAMINERGIC-NEURONS | NEUROSCIENCES | PARKINSONS-DISEASE | Colchicine - pharmacology | Tyrosine 3-Monooxygenase - metabolism | Flufenamic Acid - pharmacology | Vesicular Monoamine Transport Proteins - metabolism | Tubulin Modulators - pharmacology | Neurons - cytology | Green Fluorescent Proteins - genetics | Nimodipine - pharmacology | Corpus Striatum - cytology | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Neurons - classification | Time Factors | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Synaptic Transmission - drug effects | Lysine - metabolism | Electric Stimulation - methods | Action Potentials - drug effects | Lysine - analogs & derivatives | Anti-Inflammatory Agents - pharmacology | Synapses - physiology | Mice, Transgenic | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Pyrimidines - pharmacology | Calcium Channel Blockers - pharmacology | Cardiovascular Agents - pharmacology | GABA Antagonists - pharmacology | Action Potentials - physiology | Tyrosine 3-Monooxygenase - genetics | Animals | Cell Count - methods | Analysis of Variance | Vesicular Monoamine Transport Proteins - genetics | Corpus Striatum - drug effects | Mice | In Vitro Techniques | Index Medicus
Journal Article
Learning and Memory, ISSN 1072-0502, 04/2010, Volume 17, Issue 4, pp. 168 - 175
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 6, pp. 803 - 815
Hippocampal activity influences neurogenesis in the adult dentate gyrus; however, little is known about the involvement of the hippocampal circuitry in this... 
RAT DENTATE GYRUS | TEMPORAL-LOBE EPILEPSY | POSTNATAL MOUSE-BRAIN | PROLIFERATING CELLS | GENERATED GRANULE CELLS | CORTICAL CIRCUIT FORMATION | BEHAVING RAT | GAMMA OSCILLATIONS | PSA-NCAM | PRECURSOR CELLS | NEUROSCIENCES | Calcium - metabolism | gamma-Aminobutyric Acid - metabolism | Ki-67 Antigen - metabolism | N-Methylaspartate - pharmacology | Calbindins | Drug Interactions | Neurons - ultrastructure | Basic Helix-Loop-Helix Transcription Factors - metabolism | Neurons - metabolism | Tetrodotoxin - pharmacology | Microscopy, Immunoelectron - methods | Nickel - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | Membrane Potentials - drug effects | Sialic Acids - metabolism | gamma-Aminobutyric Acid - pharmacology | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Bicuculline - pharmacology | GABA Antagonists - pharmacology | Immunohistochemistry - methods | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Glycine - pharmacology | Green Fluorescent Proteins - biosynthesis | Mice | Nestin | Phosphopyruvate Hydratase - metabolism | Sodium-Potassium-Chloride Symporters - metabolism | Patch-Clamp Techniques - methods | Neurons - classification | Intermediate Filament Proteins - genetics | Bromodeoxyuridine - metabolism | Neural Cell Adhesion Molecule L1 - metabolism | Neurons - drug effects | Cell Differentiation - physiology | Electric Stimulation - methods | History, Ancient | Hippocampus - cytology | Membrane Potentials - physiology | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | S100 Calcium Binding Protein G - metabolism | Animals | Cell Count - methods | Solute Carrier Family 12, Member 2 | Cell Differentiation - drug effects | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Stem Cells - drug effects | In Vitro Techniques | GABA | Neurons | Cell research | Studies | Brain | Neurotransmitters | Microscopy | Neurogenesis | Rodents | Index Medicus
Journal Article
NEUROPSYCHOPHARMACOLOGY, ISSN 0893-133X, 01/2004, Volume 29, Issue 1, pp. 45 - 58
Intense or chronic stress can produce pathophysiological alterations in the systems involved in the stress response. The amygdala is a key component of the... 
GLUCOCORTICOID RECEPTOR | stress | amygdala | alpha adrenoceptors | NUCLEUS-TRACTUS-SOLITARIUS | BENZODIAZEPINE RECEPTORS | PSYCHIATRY | inhibitory synaptic transmission | ALPHA-ADRENOCEPTOR SUBTYPES | RECEPTOR MESSENGER-RNA | CYCLIC-AMP RESPONSE | GABA release | NOREPINEPHRINE RELEASE | NEUROSCIENCES | TRANSDUCTION PATHWAYS | RAT SENSORIMOTOR CORTEX | norepinelphrine | SYSTEM IN-VITRO | PHARMACOLOGY & PHARMACY | Receptors, Adrenergic, alpha-1 - metabolism | Amygdala - physiopathology | Norepinephrine - pharmacology | Amygdala - drug effects | Body Weight | gamma-Aminobutyric Acid - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Male | Adrenergic alpha-Antagonists - pharmacology | Anesthetics, Local - pharmacology | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Adrenergic beta-Antagonists - pharmacology | Propranolol - pharmacology | Drug Interactions | Time Factors | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Restraint, Physical - methods | Stress, Physiological - metabolism | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Aging | Tetrodotoxin - pharmacology | Neurons - drug effects | Animals, Newborn | Isoquinolines - metabolism | Membrane Potentials - drug effects | Amygdala - metabolism | Morpholines - pharmacology | Phosphodiesterase Inhibitors - pharmacology | Rats | Amygdala - cytology | Imidazoles - pharmacology | Bicuculline - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Animals | Tetrahydronaphthalenes - pharmacology | In Vitro Techniques | Excitatory Amino Acid Antagonists | Neural Inhibition - drug effects | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 5/2008, Volume 197, Issue 4, pp. 591 - 600
Tiagabine is an anticonvulsant drug which may also have sleep-enhancing properties. It acts by inhibiting reuptake at the gamma-aminobutyric acid (GABA)... 
Drug discrimination | Indiplon | Rat | Gabapentin | Tiagabine | Biomedicine | Gaboxadol | Bicuculline methochloride | Baclofen | GABA | Pharmacology/Toxicology | Psychiatry | Bicuculline | bicuculline methochloride | rat | GABAPENTIN NEURONTIN | PSYCHIATRY | tiagabine | GABA UPTAKE INHIBITOR | PHARMACOLOGICAL CHARACTERIZATION | ANTICONVULSANT | indiplon | baclofen | GAMMA-HYDROXYBUTYRATE | NEUROSCIENCES | A RECEPTORS | drug discrimination | gabapentin | bicuculline | IN-VIVO | PHARMACOLOGY & PHARMACY | RECEPTOR AGONIST | gaboxadol | BRAIN | Azabicyclo Compounds - pharmacology | Male | Anticonvulsants - pharmacology | Dose-Response Relationship, Drug | Discrimination Learning - drug effects | Nipecotic Acids - pharmacology | Bicuculline - analogs & derivatives | Baclofen - pharmacology | Benzodiazepines - pharmacology | Administration, Oral | GABA Plasma Membrane Transport Proteins - drug effects | Injections, Intraperitoneal | Rats | Thiophenes - pharmacology | gamma-Aminobutyric Acid - pharmacology | Bicuculline - pharmacology | Piperazines - pharmacology | GABA Antagonists - pharmacology | Brain - drug effects | Isoxazoles - pharmacology | GABA Agents - pharmacology | Animals | Cyclohexanecarboxylic Acids - pharmacology | GABA Agonists - pharmacology | Hypnotics and Sedatives - pharmacology | Pyridines - pharmacology | Amines - pharmacology | Generalization, Stimulus - drug effects | Neurology | Neurotransmitters | Biochemistry | Pharmacology | Inhibitor drugs | Rodents | Index Medicus
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 12/2005, Volume 94, Issue 6, pp. 4131 - 4144
The effects of pregnenolone sulfate (PREGS), a putative neurosteroid, on the transmission of perforant path–granule cell synapses were investigated with an... 
TRANSMITTER RELEASE | PHYSIOLOGY | GLUTAMATE RELEASE | CALCIUM-CHANNELS | LINKED-IMMUNOSORBENT-ASSAY | NICOTINIC ACETYLCHOLINE-RECEPTOR | INCREASES HIPPOCAMPAL ACETYLCHOLINE | RAT-BRAIN | ALPHA-BUNGAROTOXIN | AGED RATS | NEUROSCIENCES | METHYL-D-ASPARTATE | Excitatory Postsynaptic Potentials - radiation effects | Synaptic Transmission - physiology | Rats, Wistar | Calcium - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Kainic Acid - analogs & derivatives | Male | Nicotinic Antagonists - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Drug Interactions | Time Factors | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Pregnenolone - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Haloperidol - pharmacology | Nicotinic Agonists - pharmacology | Calcium - pharmacology | Presynaptic Terminals - drug effects | Kainic Acid - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Hippocampus - cytology | Ethylenediamines - pharmacology | GABA Antagonists - pharmacology | Animals | Benzylidene Compounds - pharmacology | Analysis of Variance | Dopamine Antagonists - pharmacology | Pyridines - pharmacology | In Vitro Techniques | Bungarotoxins - pharmacology | Index Medicus
Journal Article