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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 11/2012, Volume 32, Issue 11, pp. 2711 - 2720
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 36, pp. 24035 - 24048
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need... 
GENE | LEUCINE-RICH PROTEOGLYCANS | CASPASE-1 | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE IMMUNE-RESPONSE | HYALURONAN | IL-1-BETA | SECRETION | ATP | NALP3 INFLAMMASOME | Toll-Like Receptor 2 - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Immunity, Innate - genetics | Extracellular Matrix - metabolism | Caspase 1 - metabolism | Male | Ureteral Obstruction - metabolism | Interleukin-1beta - genetics | Inflammation - metabolism | Kidney - metabolism | Carrier Proteins - immunology | Signal Transduction | Proteoglycans - immunology | Extracellular Matrix Proteins - genetics | Proteoglycans - metabolism | Toll-Like Receptor 4 - genetics | Biglycan | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Ureteral Obstruction - immunology | Macrophages - metabolism | Receptors, Purinergic P2 - metabolism | Toll-Like Receptor 2 - immunology | Mice | Proteoglycans - genetics | Extracellular Matrix - immunology | Kidney - immunology | Caspase 1 - immunology | Extracellular Matrix - genetics | Receptors, Purinergic P2 - genetics | Ureteral Obstruction - genetics | Interleukin-1beta - biosynthesis | Lung - metabolism | Receptors, Purinergic P2 - immunology | Extracellular Matrix Proteins - metabolism | Macrophages - immunology | Carrier Proteins - biosynthesis | Interleukin-1beta - immunology | Inflammation - immunology | Protein Structure, Tertiary - genetics | Receptors, Purinergic P2X7 | Carrier Proteins - genetics | Immunity, Innate - immunology | Animals | Caspase 1 - genetics | Extracellular Matrix Proteins - immunology | Receptors, Purinergic P2X4 | Inflammation - genetics | Lung - immunology | Animal models | Reactive oxygen species | Oligomerization | Proteoglycans | Transcription | Lung | Inflammation | Macrophages | Kidney | Stress | Caspase-1 | Purine P2X receptors | Signal transduction | Cell activation | TLR2 protein | Interleukin 1 | Toll-like receptors | Extracellular matrix | Sepsis | Cooperativity | Injuries | Glycobiology and Extracellular Matrices
Journal Article
The FEBS Journal, ISSN 1742-464X, 01/2017, Volume 284, Issue 1, pp. 10 - 26
Inflammation and autophagy have emerged as prominent issues in the context of proteoglycan signaling. In particular, two small, leucine‐rich proteoglycans,... 
microtubule‐associated protein light chain 3 | receptor tyrosine kinase | biglycan | decorin | small leucine‐rich proteoglycans | Toll‐like receptors | Toll-like receptors | small leucine-rich proteoglycans | microtubule-associated protein light chain 3 | TGF-BETA | TUMOR PROGRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | VEGF EXPRESSION | BINDING-PROTEIN | GROWTH-FACTOR RECEPTOR | TOLL-LIKE | LEUCINE-RICH PROTEOGLYCANS | ENDOTHELIAL-CELLS | GENE-EXPRESSION | EXTRACELLULAR-MATRIX | Neoplasms - metabolism | Proto-Oncogene Proteins c-met - metabolism | Receptor, Epidermal Growth Factor - genetics | Neoplastic Cells, Circulating - pathology | Humans | Gene Expression Regulation, Neoplastic | Extracellular Matrix - metabolism | Neoplastic Cells, Circulating - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Autophagy | Neovascularization, Pathologic - pathology | Receptor, Epidermal Growth Factor - metabolism | Neoplasms - genetics | Cytokines - genetics | Decorin - genetics | Cytokines - metabolism | Signal Transduction | Endothelial Cells - metabolism | Biglycan - metabolism | Inflammation | Proto-Oncogene Proteins c-met - genetics | Neovascularization, Pathologic - genetics | Neovascularization, Pathologic - metabolism | Endothelial Cells - pathology | Neoplasms - pathology | Decorin - metabolism | Development and progression | Cancer | Signaling | Decorin | Proteoglycans | Extracellular matrix | Biology | Leucine | Phagocytosis | Small leucine-rich proteoglycans | LC3
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2005, Volume 115, Issue 8, pp. 2223 - 2233
Biglycan, a small leucine-rich proteoglycan, is a ubiquitous ECM component; however, its biological role has not been elucidated in detail. Here we show that... 
FACTOR-ALPHA INTERACTS | MEDICINE, RESEARCH & EXPERIMENTAL | DECORIN | SMALL PROTEOGLYCANS | DERMATAN SULFATE | DENDRITIC CELLS | RECOGNITION | INDUCED PULMONARY-FIBROSIS | GROWTH | MICE | EXPRESSION | Toll-Like Receptor 2 | Macrophages, Alveolar - pathology | Toll-Like Receptor 4 | Membrane Glycoproteins - metabolism | Extracellular Matrix - metabolism | NF-kappa B - metabolism | Extracellular Matrix - genetics | Toll-Like Receptors | Inflammation - metabolism | Sepsis - pathology | Extracellular Matrix Proteins | Sepsis - metabolism | Antigens, Differentiation - metabolism | Lung - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Lung - pathology | Lipopolysaccharides - toxicity | Proteoglycans - metabolism | Receptors, Cell Surface - metabolism | Biglycan | Signal Transduction - genetics | Myeloid Differentiation Factor 88 | Membrane Glycoproteins - genetics | Mice, Knockout | Adaptor Proteins, Signal Transducing | Animals | Sepsis - chemically induced | Signal Transduction - drug effects | Inflammation - genetics | Zymosan - toxicity | Antigens, Differentiation - genetics | Mice | Macrophages, Alveolar - metabolism | Receptors, Immunologic - genetics | Tumor Necrosis Factor-alpha - biosynthesis | Proteoglycans - genetics | Receptors, Immunologic - metabolism | Receptors, Cell Surface - genetics
Journal Article
The FEBS Journal, ISSN 1742-464X, 05/2013, Volume 280, Issue 10, pp. 2165 - 2179
Journal Article
Journal Article
PloS one, 2017, Volume 12, Issue 8, p. e0184028
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 1, pp. 237 - 250
Journal Article