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Hepatology, ISSN 0270-9139, 09/2012, Volume 56, Issue 3, pp. 1034 - 1043
Journal Article
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2017, Volume 58, Issue 1, pp. 267 - 278
As neurons die, cholesterol is released in the central nervous system (CNS); hence, this sterol and its metabolites may represent a biomarker of... 
Cytochrome p450 | Brain lipids | Cholestenoic acids | Nuclear receptors/lxr | Oxysterols | Mass spectrometry | Neurodeneneration | Bile acids and salts/biosynthesis | cholestenoic acids | brain lipids | HOMEOSTASIS | bile acids and salts/biosynthesis | LIVER-X RECEPTORS | oxysterols | nuclear receptors/LXR | BIOCHEMISTRY & MOLECULAR BIOLOGY | cytochrome P450 | CEREBROSPINAL-FLUID | BLOOD-BRAIN-BARRIER | MASS-SPECTROMETRY | neurodeneneration | PLASMA | CELL-MIGRATION | NEURONS | 27-HYDROXYCHOLESTEROL | mass spectrometry | Neurons - pathology | Bile Acids and Salts - blood | Central Nervous System - metabolism | Cholesterol - blood | Cholesterol - isolation & purification | Humans | Middle Aged | Central Nervous System - pathology | Male | Amyotrophic Lateral Sclerosis - blood | Bile Acids and Salts - cerebrospinal fluid | Nerve Degeneration - pathology | Nerve Degeneration - cerebrospinal fluid | Lipids - isolation & purification | Amyotrophic Lateral Sclerosis - pathology | Lipids - cerebrospinal fluid | Nerve Degeneration - blood | Amyotrophic Lateral Sclerosis - cerebrospinal fluid | Bile Acids and Salts - isolation & purification | Lipids - blood | Female | Aged | Neurons - metabolism | Cholesterol - cerebrospinal fluid | Neuroprotection | Acids | Metabolites | Sterols | Neurodegeneration | Central nervous system | Amyotrophic lateral sclerosis | Lipid metabolism | Cerebrospinal fluid | Cholesterol | Sclerosis | Bile | Index Medicus | nuclear receptors | Patient-Oriented and Epidemiological Research | LXR | biosynthesis | bile acids and salts
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2015, Volume 62, Issue 6, pp. 1398 - 1404
Graphical abstract 
Gastroenterology and Hepatology | 3-hydroxy-3-methylglutaryl-CoA reductase | Stearoyl-CoA desaturase | Non-alcoholic fatty liver disease | Lipogenesis | FGF19 | 3-hydroxy-3-methylglutaryl- CoA reductase | Ursodeoxycholic Acid - administration & dosage | Oleic Acid - metabolism | Bile Acids and Salts - biosynthesis | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Non-alcoholic Fatty Liver Disease - metabolism | Intra-Abdominal Fat - metabolism | Obesity, Morbid - drug therapy | Non-alcoholic Fatty Liver Disease - drug therapy | Ursodeoxycholic Acid - pharmacology | Stearoyl-CoA Desaturase - biosynthesis | Liver - drug effects | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Lipid Metabolism - drug effects | Intra-Abdominal Fat - drug effects | Obesity, Morbid - metabolism | Physiological aspects | Obesity | Ursodiol | Deoxycholic acid | Index Medicus | BAs, bile acids | nCEH, neutral cholesterol ester hydrolase | ApoB, apolipoprotein B | LDLR, low density lipoprotein receptor | FGF19, fibroblast growth factor 19 | VLDL, very low density lipoproteins | ABC, ATP-binding cassette | TGs, triglycerides | NAFLD, non-alcoholic fatty liver disease | OA, oleic acid | C4, 7α-hydroxy-4-cholesten-3-one | SHP, small heterodimer partner | SREBP1c, sterol regulatory element-binding protein-1c | CA, cholic acid | PA, palmitic acid | FATP1, fatty acid transport protein 1 | UDCA, ursodeoxycholic acid | FAs, fatty acides | HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase | vWAT, visceral white adipose tissue | SCD, stearoyl-Coa desaturase | CYP7A1, cholesterol 7α-hydroxylase | NASH, non-alcoholic steatohepatitis | FXR, farnesoid X receptor | CDCA, chenodeoxycholic acid | MA, myristic acid | FASN, fatty acid synthase | MTTP, microsomal triglyceride transfer protein | SA, stearic acid | NONALCOHOLIC | FATTY LIVER-DISEASE | NUCLEAR RECEPTOR | CHOLESTEROL-METABOLISM | Gastroenterology & Hepatology | TRANSPORT | Endokrinologi och diabetes | FEEDBACK-REGULATION | STEATOHEPATITIS | PLACEBO-CONTROLLED TRIAL | COA DESATURASE | EXPRESSION | Endocrinology and Diabetes | ADIPOSE-TISSUE
Journal Article
Genes and Development, ISSN 0890-9369, 07/2003, Volume 17, Issue 13, pp. 1581 - 1591
The nuclear bile acid receptor FXR has been proposed to play a central role in the feedback repression of the gene encoding cholesterol 7alpha-hydroxylase... 
Fibroblast growth factor | FXR | CYP7A1 | Bile acid | JNK | RAT HEPATOCYTES | bile acid | NEGATIVE FEEDBACK-REGULATION | SALT EXPORT PUMP | N-TERMINAL KINASE | DEVELOPMENTAL BIOLOGY | ORPHAN NUCLEAR RECEPTOR | RESPONSIVE ELEMENT | CELL BIOLOGY | fibroblast growth factor | GENETICS & HEREDITY | RETINOID-X-RECEPTOR | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | TRANSCRIPTIONAL REGULATION | TRANSGENIC MICE | Phosphorylation | Humans | Fibroblast Growth Factors - genetics | Hepatocytes - metabolism | Receptors, Cytoplasmic and Nuclear | DNA-Binding Proteins - metabolism | Fibroblast Growth Factors - metabolism | Transfection | DNA-Binding Proteins - agonists | Chenodeoxycholic Acid - pharmacology | JNK Mitogen-Activated Protein Kinases | Cell Line | Bile Acids and Salts - biosynthesis | Response Elements | Signal Transduction | Cells, Cultured | Gene Expression Regulation | Fibroblast Growth Factors - pharmacology | Recombinant Proteins - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Anthracenes - pharmacology | Isoxazoles - pharmacology | Transcription Factors - metabolism | Cholesterol 7-alpha-Hydroxylase - genetics | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cholesterol 7-alpha-Hydroxylase - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Mice | Transcription Factors - agonists | Enzyme Repression | Mitogen-Activated Protein Kinases - metabolism | Bile acids | Analysis | Physiological aspects | Genetic research | Genetic aspects | Biosynthesis | Gene expression | Growth factors | Cholesterol | Index Medicus | Research Papers
Journal Article